JP2008056641A - External preparation for skin - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an external preparation for skin, containing an unsaturated fatty acid, especially a leave-on type external preparation for skin, which can mask or harmonize the odor of the unsaturated fatty acid, when coated on the skin, can pleasantly be used by users, can leave the pleasant odor for several hours after coated, and can retain the effect for masking the odor of the unsaturated fatty acid for a long time. <P>SOLUTION: This external preparation for skin comprises ingredients (A) and (B). The ingredient (A) : a 14 to a18C unsaturated fatty acid ingredient, and the ingredient (B) : a perfume composition comprising perfume ingredients (b1) and (b2). The ingredient (b1) : a floral perfume, and the ingredient (b2) : a woody or musk perfume. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

The present invention relates to a skin external preparation containing an unsaturated fatty acid.
About.

  Many examples of blending unsaturated fatty acids and their derivatives into a detergent composition as a cosmetic base have been reported (Patent Documents 1 to 3). Patent Document 1 discloses a detergent composition containing a basic amino acid fatty acid salt, Patent Document 2 discloses a liquid detergent composition mainly composed of oleate, and Patent Document 3 discloses oleic acid. A contained body shampoo is disclosed. Various fragrance | flavors are mix | blended with these compositions for the purpose of the masking of a fatty acid, etc.

  However, in the detergent composition that is washed away with water, the unsaturated fatty acid is also washed away, but recently, an example of using the unsaturated fatty acid as a leave-on (not washed away) skin external preparation has been reported (Patent Document 4). ).

  In the leave-on skin external preparation, it is necessary to mask the base odor derived from the unsaturated fatty acid for about the second half day (several hours) from the beginning of use due to the product characteristic of being left on. In addition, if the amount of unsaturated fatty acid remaining on the skin is large, there is a problem that uncomfortable feelings are caused to the user himself and those around him. However, Patent Document 4 also does not report at all about the problem of base odor derived from unsaturated fatty acids and the deodorization of base odor.

Japanese Patent Laid-Open No. 4-183797 JP-A 62-79300 JP 2002-327193 A JP 2005-126426 A

  The present invention provides a skin external preparation containing an unsaturated fatty acid, particularly a leave-on type product, which masks or harmonizes the odor of the unsaturated fatty acid when applied to the skin, can be used comfortably for the user, and is comfortable for several hours after application. An object of the present invention is to provide an external preparation for skin that leaves a scent and can maintain the masking effect of unsaturated fatty acid odor for a long time.

  The present inventor can effectively mask an odor derived from an unsaturated fatty acid by blending a fragrance composition containing a combination of specific fragrance ingredients with a skin external preparation containing an unsaturated fatty acid. It was found that a gentle and warm residual scent was obtained that could not be obtained by using the scent, and that the residual scent lasted effectively for a long time.

The present invention provides a skin external preparation containing components (A) and (B).
Component (A); unsaturated fatty acid component having 14 to 18 carbon atoms (B); fragrance composition containing fragrance components (b1) and (b2) fragrance component (b1): methyl dihydrojasmonate, hexylcinnamic aldehyde, Tetrahydrolinalool, tetrahydrogeraniol, dihydrolinalool, 2-methyl-3- (4-tert-butylphenyl) -propanal, 4- (4-hydroxy-4-methylpentyl) -3-cyclohexene-1-carboxaldehyde, 4 -Methyl-2- (2-methylpropyl) tetrahydro-2H-4-pyranol, p-isobutyl-α-methylhydrocinnamic aldehyde, methyl anthranilate, dihydroeugenol, eugenol, 7-methyl-3,4-dihydro- (2H) -1,5-benzodioxepin-3-one, α-damascone, β-damascone, damacenone, undecylene aldehyde, hexyl salicylate, cis-3-hexenyl salicylate and γ- One or more perfume materials selected from undecalactone. Perfume component (b2): Acetyl cedrene, 7-acetyl-1,2,3,4,5,6,7,8-octahydro-1,1 , 6,7-Tetramethylnaphthalene, 1- (2-tert-butylcyclohexyloxy) -2-butanol, α-ionone, β-ionone, methylionone, 3α, 6,6,9α-tetramethyldodecahydronaphtho [2 , 1-b] furan, 2- (2,4-dimethyl-3-cyclohexen-1-yl) -5-methyl-5- (1-methylpropyl) -1,3-dioxane, 2-methyl-4- (2,2,3-trimethyl-3-cyclopenten-1-yl) -2-buten-1-ol, 2-ethyl-4- (2,2,3-trimethyl-3-cyclopenten-1-yl)- 2-buten-1-ol, patchouli oil, 4,6,6,7,8,8-hexamethyl-1,3,4,6,7,8-hexahydrocyclopentabenzopyran, cyclopentadecanolide, Cyclopentadecenolide, ethylene brassylate, coumarin and vanillic One or more flavoring materials selected from

  For external preparations containing unsaturated fatty acids, especially leave-on products, masking or harmonizing the odor of unsaturated fatty acids when applied to the skin, leaving the scent pleasant for the user for a few hours after application, leaving The masking effect of saturated fatty acid odor can be maintained for a long time.

  In the present invention, “external preparation for skin” refers to a cosmetic preparation, quasi-drug preparation or pharmaceutical preparation for skin, which is not washed off after being applied to the skin. Specific examples of such preparations include antiperspirants, deodorants, lotions, creams, mousses, ointments, liquids, poultices and the like.

  Examples of the unsaturated fatty acid having 14 to 18 carbon atoms of component (A) include myristoleic acid, cis-6-hexadecenoic acid, oleic acid (cis-9-octadecenoic acid), linoleic acid, linolenic acid and the like.

  The unsaturated fatty acid can be used alone or in combination of two or more, and the content thereof is 0.00005 to 20% by mass, more preferably 0.0001 to 10% by mass, particularly 0.001 in the external preparation for skin of the present invention. -5 mass% is preferable.

  The fragrance composition of component (B) uses two groups of fragrance materials, the fragrance component (b1) and the fragrance component (b2).

  The fragrance component (b1) is a floral-type fragrance that masks or harmonizes the odor of unsaturated fatty acid when applied to the skin, and is a component that is gentle and has a flowery scent. Fragrance component (b1) is methyl dihydrojasmonate, hexylcinnamic aldehyde, tetrahydrolinalol, tetrahydrogeraniol, dihydrolinalol, 2-methyl-3- (4-tert-butylphenyl) -propanal (Givaudan trade name: Lilianal) ), 4- (4-hydroxy-4-methylpentyl) -3-cyclohexene-1-carboxaldehyde (trade name: Lilal, IFF), 4-methyl-2- (2-methylpropyl) tetrahydro-2H-4- Pyranol (Quest product name: Florosa), p-isobutyl-α-methylhydrocinnamic aldehyde (Takasago International Corporation product name: Suzaral), methyl anthranilate, dihydroeugenol, eugenol, 7-methyl-3,4-dihydro -(2H) -1,5-benzodioxepin-3-one (Danisco trade name: Calone), α-Damascon, β-Damascon, Damasenone, Undeci Emissions aldehyde, hexyl salicylate, composed of one or more perfume materials selected from cyclohexenyl salicylic cis-3-and γ- undecalactone.

  Fragrance component (b2) is a woody or musk-like fragrance that leaves a pleasant scent for several hours after application and maintains the masking effect of unsaturated fatty acid odor for a long time, mainly warm like wood and vanilla It is a component having The fragrance component (b2) is acetyl cedrene, 7-acetyl-1,2,3,4,5,6,7,8-octahydro-1,1,6,7-tetramethylnaphthalene (IFF trade name: ISOE Super), 1- (2-tert-butylcyclohexyloxy) -2-butanol (Kao Corporation trade name: Ambercore), α-ionone, β-ionone, methylionone, 3α, 6,6,9α-tetramethyl Dodecahydronaphtho [2,1-b] furan (Kao Corporation trade name: Ambroxan), 2- (2,4-dimethyl-3-cyclohexen-1-yl) -5-methyl-5- (1-methylpropyl) ) -1,3-Dioxane (trade name of Quest, caranal), 2-methyl-4- (2,2,3-trimethyl-3-cyclopenten-1-yl) -2-buten-1-ol (Kaosha) Product name: Sandal Mysole Core), 2-ethyl-4- (2,2,3-trimethyl-3-cyclopenten-1-yl) -2-buten-1-ol (IFF product name: Vacdanol), patchouli oil 4,6,6,7,8,8-hexamethyl-1,3,4,6 , 7,8-Hexahydrocyclopentabenzopyran (IFF brand name: Galaxolide), cyclopentadecanolide, cyclopentadecenolide (Firmenich brand name: havanolide), ethylene brassylate, coumarin and vanillin It consists of one or more perfume materials.

  If one or more of these groups are selected and used in a balanced manner, the odor of unsaturated fatty acids can be masked or well harmonized, and a gentle and warm residual scent can be provided. The content of the fragrance component (b1) in the fragrance composition of the component (B) is preferably 0.001 to 90 mass%, more preferably 0.1 to 70 mass%, and particularly preferably 5 to 40 mass%. The content of the fragrance component (b2) in the fragrance composition of the component (B) is preferably 0.001 to 90 mass%, more preferably 0.1 to 60 mass%, and particularly preferably 5 to 30 mass%.

  The mass ratio of the fragrance components (b1) and (b2) can be adjusted as appropriate according to the strength of the fragrance, but is 1: 9 to 9: 1, more preferably 2: 8 to 8: 2. Especially 3: 7-7: 3 is preferable. Moreover, it is preferable that the total ratio of the fragrance | flavor component (b1) and (b2) is 10-100 mass% in a fragrance | flavor composition (B), Furthermore, 30-90 mass%, It is especially 50-80 mass%.

To the fragrance component of the present invention, other fragrance components can be added in order to expand the range of the fragrance tone and increase the refreshingness and brightness. Other perfume ingredients include citral, 2,6-dimethyl-2-heptanol (Givaudan trade name: Dimethol), geranyl nitrile, eucalyptol, ethyl butyrate, ethyl tricyclo [5.2.1.0 ^2,6 ] decane-2 -Il carboxylate (trade name: Kao Fruate), ethyl 2-cyclohexyl propionate (trade name: Kaolein), δ-damascone, ethyl methylphenylglycidate, decylaldehyde, undecylaldehyde, dodecylaldehyde, methylnonyl Acetaldehyde, l-carvone, anethole, cis-3-hexenol, cis-3-hexenyl acetate, 2,4-dimethyl-3-cyclohexenyl carboxaldehyde (IFF company name; tripral, styrylyl acetate, allyl amyl glycolate, acetic acid Isobornyl, benzaldehyde, linalool, vinegar Linalyl, linalool oxide, cis jasmon, phenylethyl alcohol, benzyl acetate, geraniol, citronellol, p-cresol, maltol, lime oil, lavender oil, basil oil, rosemary oil, cumin oil, lemon oil, 3,5,5- Trimethylcyclohexanol, hexyl aldehyde, octyl aldehyde, nonyl aldehyde, allyl caproate, allyl enanthate, 4-methoxybenzaldehyde, 4-isopropyl-5,5-dimethyl-1,3-dioxane, α-pinene, β-pinene, 3-phenyl-1-propen-1-ol, cis-3-hexenyl butyrate, 3,7-dimethyl-2,6-octadienal, 3,7-dimethyl-6-octen-1-ol, dimethyl malonate , Dimethylbenzyl carvinyl acetate, l-menthol, ethyl-2-methyl butyrate, ethyl acetate, ethyl acetoacetate, isobutyric acid , Ethyl maltol, ethyl n-butyrate, ethyl captinate, ethyl propionate, 1,8-cineol, 3,4-methylenedioxybenzaldehyde, hexyl acetate, 7-hydroxy-3,7-dimethyloctane-1-al , Indole, ethyl 2-methylbutyrate, isoamyl acetate, isoamyl n-butyrate, isobutyl acetate, limonene, 3-hydroxy-2-methyl-4H-pyran-4-one, methyl benzoate, 3,7-dimethyl-cis- 2,6-octadien-1-ol, p-cresyl acetate, p-cresyl methyl ether, 2-methylpentyl pentanoate, phenylacetaldehyde, phenylethyl acetate, ethyl 2-cyclohexyl propionate, 2-cyclohexylpropanal, 1 -Phenylethyl acetate, styryl propionate, terpineol, 4-methyl-3-decen-5-ol, 2,2,5,5-tetramethyl-4-isopropyl-1 One and two or more perfume ingredients selected from the group consisting of 3-dioxane.

  The content of the other fragrance components is preferably 0 to 90 mass%, more preferably 10 to 70 mass%, and particularly preferably 20 to 50 mass% in the fragrance composition (B). In addition, in this invention, the calculation of content of a fragrance | flavor component shall not include the solvent and diluent contained in a fragrance | flavor composition.

  The content of the fragrance composition of component (B) is 0.0001 to 5% by mass in the skin external preparation of the present invention, and further 0.001 from the point that both the masking of odors derived from unsaturated fatty acids and the warm residual fragrance can be achieved. -3 mass%, especially 0.01-3 mass% is preferable. When the skin external preparation of the present invention is an antiperspirant or a deodorant, the content of component (B) is preferably 0.0001 to 5% by mass, more preferably 0.001 to 3% by mass, and particularly preferably 0.01 to 1.5% by mass. When the skin external preparation of the present invention is a body lotion, the content of the component (B) is preferably 0.0001 to 2% by mass, more preferably 0.001 to 1% by mass, and particularly preferably 0.01 to 0.7% by mass.

  The skin external preparation of the present invention may further contain a bactericidal agent, an antibacterial agent, an antiperspirant, a chelating agent, a pH adjusting agent, a pigment, a viscosity adjusting agent, a moisturizing agent, etc. Manufactured by the method. Further, these materials may be used after being diluted with a volatile solvent such as water, ethanol, low molecular weight hydrocarbons, liquid LPG gas, dimethyl ether or the like. When the material is dispersed and solubilized in water, a surfactant such as cationic, anionic, nonionic or amphoteric can be added as a solubilizer.

  Examples of the product form of the external preparation for skin of the present invention include direct application type (for example, roll-on type), wiping type, pump spray type, aerosol spray type, capsule type and the like. In addition, the fragrance composition of component (B) may be blended in a fragrance, a deodorant, a fragrance deodorant, a garment detergent, a garment finish, a softener, and the like.

  Antiperspirants (pump spray type) shown in Table 3 were prepared using the fragrance compositions shown in Tables 1 and 2 (Prescription Examples 1 to 7), and the following evaluation experiments were performed. In the following examples, “%” represents “mass%”.

<Evaluation experiment>
An antiperspirant composition (Table 3) was prepared using the prepared perfume ingredients (Formulation Examples 1 to 7; Tables 1 and 2). Spray about 0.5g of antiperspirant composition in a spray vial (Marem Co., No.6) on the left upper arm of a total of 8 specialist panelists, to show the masking effect of unsaturated fatty acid odor and its sustainability Sensory evaluation was performed. The evaluation result was an average value of the evaluation results of eight people.
During the evaluation, subjects were engaged in light work such as document preparation, mainly in a room maintained at room temperature (25 ° C) and humidity of 65%. When going out of the evaluation room, intense exercise accompanied by a large amount of perspiration and exposure to direct sunlight on the antiperspirant application part were avoided.
The evaluation results are shown in Table 4.

<Evaluation criteria for unsaturated fatty acid odor masking effect>
Masked completely and feels comfortable +1
0
I feel uncomfortable with insufficient masking -1

As a result of the evaluation, Example 1 is feminine and high-quality scent, Example 2 is fresh and gentle as a flower, Example 3 is soft and warm and gentle, and Example 4 is refreshing citrus. All of them have masked the odor of unsaturated fatty acids, and have a gentle, warm and pleasant lingering scent.
On the other hand, Comparative Example 1 masked the fatty acid odor well immediately after application and was comfortable, but after 1 hour and 4 hours, masking became insufficient and felt uncomfortable. On the other hand, Comparative Example 2 was comfortable because it masked the fatty acid odor well after 1 hour and after 4 hours, but it felt uncomfortable due to insufficient masking immediately after application. In Comparative Example 3, immediately after application, the remaining scent was insufficiently masked and felt uncomfortable.

Claims (2)

An external preparation for skin containing components (A) and (B).
Component (A): C14-18 unsaturated fatty acid component (B): Perfume composition containing perfume components (b1) and (b2) Perfume component (b1): methyl dihydrojasmonate, hexylcinnamic aldehyde, Tetrahydrolinalool, tetrahydrogeraniol, dihydrolinalool, 2-methyl-3- (4-tert-butylphenyl) -propanal, 4- (4-hydroxy-4-methylpentyl) -3-cyclohexene-1-carboxaldehyde, 4 -Methyl-2- (2-methylpropyl) tetrahydro-2H-4-pyranol, p-isobutyl-α-methylhydrocinnamic aldehyde, methyl anthranilate, dihydroeugenol, eugenol, 7-methyl-3,4-dihydro- (2H) -1,5-benzodioxepin-3-one, α-damascone, β-damascone, damacenone, undecylene aldehyde, hexyl salicylate, cis-3-hexenyl salicylate and γ- One or more perfume materials selected from undecalactone. Perfume component (b2): Acetyl cedrene, 7-acetyl-1,2,3,4,5,6,7,8-octahydro-1,1 , 6,7-Tetramethylnaphthalene, 1- (2-tert-butylcyclohexyloxy) -2-butanol, α-ionone, β-ionone, methylionone, 3α, 6,6,9α-tetramethyldodecahydronaphtho [2 , 1-b] furan, 2- (2,4-dimethyl-3-cyclohexen-1-yl) -5-methyl-5- (1-methylpropyl) -1,3-dioxane, 2-methyl-4- (2,2,3-trimethyl-3-cyclopenten-1-yl) -2-buten-1-ol, 2-ethyl-4- (2,2,3-trimethyl-3-cyclopenten-1-yl)- 2-buten-1-ol, patchouli oil, 4,6,6,7,8,8-hexamethyl-1,3,4,6,7,8-hexahydrocyclopentabenzopyran, cyclopentadecanolide, Cyclopentadecenolide, ethylene brassylate, coumarin and vanillic One or more flavoring materials selected from   The skin external preparation according to claim 1, wherein the component (A) is one or more unsaturated fatty acids selected from myristoleic acid, cis-6-hexadecenoic acid, oleic acid, linoleic acid and linolenic acid.