JP2007534772A - ヒト肝細胞癌細胞を特異的に標的化するための方法および組成物 - Google Patents

ヒト肝細胞癌細胞を特異的に標的化するための方法および組成物 Download PDF

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Publication number
JP2007534772A
JP2007534772A JP2007510987A JP2007510987A JP2007534772A JP 2007534772 A JP2007534772 A JP 2007534772A JP 2007510987 A JP2007510987 A JP 2007510987A JP 2007510987 A JP2007510987 A JP 2007510987A JP 2007534772 A JP2007534772 A JP 2007534772A
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seq
polypeptide
nos
group
antibody
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JP2007510987A
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Japanese (ja)
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JP2007534772A5 (enExample
Inventor
ガリー ローゼンバーグ,
ショーン ピー. イアドナト,
Original Assignee
イルミジェン バイオサイエンシーズ, インコーポレイテッド
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Application filed by イルミジェン バイオサイエンシーズ, インコーポレイテッド filed Critical イルミジェン バイオサイエンシーズ, インコーポレイテッド
Publication of JP2007534772A publication Critical patent/JP2007534772A/ja
Publication of JP2007534772A5 publication Critical patent/JP2007534772A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303Liver or Pancreas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
JP2007510987A 2004-04-27 2005-04-27 ヒト肝細胞癌細胞を特異的に標的化するための方法および組成物 Pending JP2007534772A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56568804P 2004-04-27 2004-04-27
PCT/US2005/014668 WO2005104785A2 (en) 2004-04-27 2005-04-27 Methods and compositions for specifically targeting human hepatocellular carcinoma cells

Publications (2)

Publication Number Publication Date
JP2007534772A true JP2007534772A (ja) 2007-11-29
JP2007534772A5 JP2007534772A5 (enExample) 2008-06-19

Family

ID=35242179

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007510987A Pending JP2007534772A (ja) 2004-04-27 2005-04-27 ヒト肝細胞癌細胞を特異的に標的化するための方法および組成物

Country Status (4)

Country Link
US (1) US20080152650A1 (enExample)
EP (1) EP1755669A4 (enExample)
JP (1) JP2007534772A (enExample)
WO (1) WO2005104785A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020189874A (ja) * 2017-08-25 2020-11-26 ストーク セラピューティクス,インク. 状態および疾患の処置のためのアンチセンスオリゴマー
US12338437B2 (en) 2020-05-11 2025-06-24 Stoke Therapeutics, Inc. OPA1 antisense oligomers for treatment of conditions and diseases

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090038023A1 (en) 2005-03-10 2009-02-05 Verenium Corporation Lyase Enzymes, Nucleic Acids Encoding Them and Methods For Making and Using Them
WO2008118176A2 (en) * 2006-06-02 2008-10-02 Verenium Corporation Lase enzymes, nucleic acids encoding them and methods for making and using them
EP2388338A1 (en) * 2010-04-30 2011-11-23 Medizinische Hochschule Hannover Method for determination of and medicament for influencing the activity of the immune system
CN114935651A (zh) * 2022-04-27 2022-08-23 广州源康生物医药科技有限公司 一种肿瘤生物标志物及应用
WO2024180461A1 (en) * 2023-02-27 2024-09-06 Ebrahiminik Hojat Integrated system for ethanol ablation and radiofrequency ablation of thyroid nodules

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002512524A (ja) * 1997-06-03 2002-04-23 財団法人相模中央化学研究所 膜貫通ドメインを有するヒト蛋白質及びそれをコードするdna
EP1217066A1 (en) * 2000-12-21 2002-06-26 Universiteit Gent Modulation of ATP-binding cassette transporter activity
US20040068096A1 (en) * 2001-09-21 2004-04-08 Zenta Tsuchihashi Human single nucleotide polymorphisms in organic anion transport and multi-drug resistant proteins
US20070166704A1 (en) * 2002-01-18 2007-07-19 Fei Huang Identification of polynucleotides and polypeptide for predicting activity of compounds that interact with protein tyrosine kinases and/or protein tyrosine kinase pathways
WO2003083046A2 (en) * 2002-03-08 2003-10-09 Curagen Corporation Novel proteins and nucleic acids encoding same
AU2003230838A1 (en) * 2002-04-05 2003-10-27 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Methods of diagnosing potential for metastasis or developing hepatocellular carcinoma and of identifying therapeutic targets

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020189874A (ja) * 2017-08-25 2020-11-26 ストーク セラピューティクス,インク. 状態および疾患の処置のためのアンチセンスオリゴマー
JP7420679B2 (ja) 2017-08-25 2024-01-23 ストーク セラピューティクス,インク. 状態および疾患の処置のためのアンチセンスオリゴマー
JP2024045199A (ja) * 2017-08-25 2024-04-02 ストーク セラピューティクス,インク. 状態および疾患の処置のためのアンチセンスオリゴマー
US12338437B2 (en) 2020-05-11 2025-06-24 Stoke Therapeutics, Inc. OPA1 antisense oligomers for treatment of conditions and diseases

Also Published As

Publication number Publication date
WO2005104785A3 (en) 2006-05-26
WO2005104785A2 (en) 2005-11-10
EP1755669A4 (en) 2008-06-25
US20080152650A1 (en) 2008-06-26
EP1755669A2 (en) 2007-02-28

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