JP2007523650A - 転移を阻害するための方法および組成物 - Google Patents
転移を阻害するための方法および組成物 Download PDFInfo
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
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- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54480704P | 2004-02-13 | 2004-02-13 | |
| US62672604P | 2004-11-10 | 2004-11-10 | |
| US11/056,825 US7271245B2 (en) | 2004-02-13 | 2005-02-11 | Methods and compositions for inhibition of metastasis |
| PCT/US2005/004612 WO2005091805A2 (en) | 2004-02-13 | 2005-02-14 | Methods and compositions for inhibition of metastasis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007523650A true JP2007523650A (ja) | 2007-08-23 |
| JP2007523650A5 JP2007523650A5 (enExample) | 2008-04-03 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006553317A Withdrawn JP2007523650A (ja) | 2004-02-13 | 2005-02-14 | 転移を阻害するための方法および組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7271245B2 (enExample) |
| EP (1) | EP1725111A4 (enExample) |
| JP (1) | JP2007523650A (enExample) |
| CA (1) | CA2559480A1 (enExample) |
| WO (1) | WO2005091805A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011508738A (ja) * | 2007-12-26 | 2011-03-17 | バイオテスト・アクチエンゲゼルシヤフト | Ｃｄ１３８発現腫瘍細胞のターゲティングを向上させる方法及び剤 |
| US9593166B2 (en) | 2013-03-14 | 2017-03-14 | Bayer Healthcare Llc | Monoclonal antibodies against antithrombin β |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004003144A2 (en) * | 2002-07-01 | 2004-01-08 | Human Genome Sciences, Inc. | Antibodies that specifically bind to reg iv |
| AR045563A1 (es) * | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
| RS54984B1 (sr) * | 2005-07-18 | 2016-11-30 | Amgen Inc | Humana anti-b7rp1 neutrališuća antitela |
| EP2082234B1 (en) * | 2006-11-02 | 2012-10-03 | Procognia (Israel) Ltd. | Methods for screening for therapeutic molecules and use of the molecules therefrom |
| US7943728B2 (en) * | 2006-12-26 | 2011-05-17 | National Cheng Kung University | Disintegrin variants and their use in treating osteoporosis-induced bone loss and angiogenesis-related diseases |
| WO2009042917A1 (en) * | 2007-09-28 | 2009-04-02 | The General Hospital Corporation | Methods and compositions for antibody production |
| WO2009070753A2 (en) * | 2007-11-28 | 2009-06-04 | The Scripps Research Institute | Bivalent single chain fv antibody compositions that specifically bind to integrin receptor on a metastatic cell in a mammalian subject |
| WO2009114816A2 (en) * | 2008-03-14 | 2009-09-17 | The Board Of Trustees Of The University Of Illinois | Therapeutic cancer antigens |
| WO2010017083A1 (en) * | 2008-08-04 | 2010-02-11 | Wayne State University | Methods of treating cancer with cd11b antibodies |
| US11180812B2 (en) | 2012-08-17 | 2021-11-23 | Cornell University | Use of DNA in circulating exosomes as a diagnostic marker for metastatic disease |
| PH12022550138A1 (en) | 2013-03-13 | 2023-03-06 | Amgen Inc | Proteins specific for baff and b7rp1 and uses thereof |
| US9458246B2 (en) | 2013-03-13 | 2016-10-04 | Amgen Inc. | Proteins specific for BAFF and B7RP1 |
| WO2015048413A1 (en) * | 2013-09-30 | 2015-04-02 | X-Body Biosciences, Inc. | Antigen receptor screening assay |
| WO2015153732A2 (en) | 2014-04-01 | 2015-10-08 | Cornell University | Use of double-stranded dna in exosomes: a novel biomarker in cancer detection |
| US11397182B2 (en) | 2014-10-07 | 2022-07-26 | Cornell University | Methods for prognosing and preventing metastatic liver disease |
| WO2016172710A2 (en) | 2015-04-24 | 2016-10-27 | Cornell University | Methods and reagents for determination and treatment of organotropic metastasis |
| WO2019241847A1 (en) * | 2018-06-22 | 2019-12-26 | Baker Heart and Diabetes Institute | A therapeutic gpiib/iiia binding-protein drug conjugate and use thereof |
| WO2020176605A1 (en) * | 2019-02-26 | 2020-09-03 | The University Of Vermont And State Agricultural College | Antibodies to neoantigens and uses thereof |
| US11883432B2 (en) | 2020-12-18 | 2024-01-30 | Century Therapeutics, Inc. | Chimeric antigen receptor system with adaptable receptor specificity |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9125979D0 (en) * | 1991-12-06 | 1992-02-05 | Wellcome Found | Antibody |
| DE69322860T2 (de) | 1992-04-03 | 1999-07-01 | Genentech, Inc., South San Francisco, Calif. | Antikörper gegen alpha v beta 3 integrin |
| US5753230A (en) | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
| KR0119887B1 (ko) | 1994-06-08 | 1997-10-30 | 김광호 | 반도체 메모리장치의 웨이퍼 번-인 테스트 회로 |
| US6596850B1 (en) | 1998-01-30 | 2003-07-22 | Ixsys, Incorporated | Anti-αv3β3 recombinant human antibodies, nucleic acids encoding same |
| JP2001521520A (ja) | 1997-04-11 | 2001-11-06 | ジー．ディー．サール アンド カンパニー | 抗α▲下ｖ▼β▲下３▼インテグリン抗体アンタゴニスト |
| WO1998046265A1 (en) | 1997-04-11 | 1998-10-22 | G.D. Searle & Co. | Methods for using antagonistic anti-avb3 integrin antibodies |
| US6406693B1 (en) | 1998-07-13 | 2002-06-18 | Board Of Regents, The University Of Texas System | Cancer treatment methods using antibodies to aminophospholipids |
| NZ511937A (en) | 1998-12-04 | 2004-02-27 | Novartis Ag | Methods and compositions for targeting an activated vitronectin receptor with a ligand comprising adenovirus-2 penton base or fragment thereof |
| US6531580B1 (en) | 1999-06-24 | 2003-03-11 | Ixsys, Inc. | Anti-αvβ3 recombinant human antibodies and nucleic acids encoding same |
| AU2001282977A1 (en) | 2000-07-26 | 2002-02-05 | The Burnham Institute | Screening methods based on superactivated alphavbeta3 integrin |
| AU2002337954C1 (en) | 2001-10-22 | 2008-10-23 | The Scripps Research Institute | Integrin targeting compounds |
| CA2478239A1 (en) | 2002-03-04 | 2003-09-18 | Medimmune, Inc. | The prevention or treatment of cancer using integrin alphavbeta3 antagonists in combination with other agents |
-
2005
- 2005-02-11 US US11/056,825 patent/US7271245B2/en not_active Expired - Fee Related
- 2005-02-14 WO PCT/US2005/004612 patent/WO2005091805A2/en not_active Ceased
- 2005-02-14 JP JP2006553317A patent/JP2007523650A/ja not_active Withdrawn
- 2005-02-14 CA CA002559480A patent/CA2559480A1/en not_active Abandoned
- 2005-02-14 EP EP05760713A patent/EP1725111A4/en not_active Withdrawn
-
2007
- 2007-08-01 US US11/832,570 patent/US20090117096A1/en not_active Abandoned
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011508738A (ja) * | 2007-12-26 | 2011-03-17 | バイオテスト・アクチエンゲゼルシヤフト | Ｃｄ１３８発現腫瘍細胞のターゲティングを向上させる方法及び剤 |
| US9446146B2 (en) | 2007-12-26 | 2016-09-20 | Biotest Ag | Methods and agents for improving targeting of CD138 expressing tumor cells |
| US9593166B2 (en) | 2013-03-14 | 2017-03-14 | Bayer Healthcare Llc | Monoclonal antibodies against antithrombin β |
| US9908942B2 (en) | 2013-03-14 | 2018-03-06 | Bayer Healthcare, Llc | Monoclonal antibodies against antithrombin β |
| US10144784B2 (en) | 2013-03-14 | 2018-12-04 | Bayer Healthcare Llc | Monoclonal antibodies against antithrombin beta |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1725111A4 (en) | 2008-08-06 |
| US7271245B2 (en) | 2007-09-18 |
| CA2559480A1 (en) | 2005-10-06 |
| EP1725111A2 (en) | 2006-11-29 |
| US20090117096A1 (en) | 2009-05-07 |
| WO2005091805A3 (en) | 2006-09-08 |
| WO2005091805A2 (en) | 2005-10-06 |
| US20050255109A1 (en) | 2005-11-17 |
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