JP2007515250A5 - - Google Patents
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- Publication number
- JP2007515250A5 JP2007515250A5 JP2006547035A JP2006547035A JP2007515250A5 JP 2007515250 A5 JP2007515250 A5 JP 2007515250A5 JP 2006547035 A JP2006547035 A JP 2006547035A JP 2006547035 A JP2006547035 A JP 2006547035A JP 2007515250 A5 JP2007515250 A5 JP 2007515250A5
- Authority
- JP
- Japan
- Prior art keywords
- stent
- poly
- agent
- mpa
- tensile strength
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000000463 material Substances 0.000 claims 10
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical group CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims 3
- WHBMMWSBFZVSSR-UHFFFAOYSA-N 3-hydroxybutyric acid Chemical compound CC(O)CC(O)=O WHBMMWSBFZVSSR-UHFFFAOYSA-N 0.000 claims 2
- 102000009123 Fibrin Human genes 0.000 claims 2
- 108010073385 Fibrin Proteins 0.000 claims 2
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 2
- 229920000954 Polyglycolide Polymers 0.000 claims 2
- 239000003146 anticoagulant agent Substances 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229950003499 fibrin Drugs 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 229920001432 poly(L-lactide) Polymers 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- PUDHBTGHUJUUFI-SCTWWAJVSA-N (4r,7s,10s,13r,16s,19r)-10-(4-aminobutyl)-n-[(2s,3r)-1-amino-3-hydroxy-1-oxobutan-2-yl]-19-[[(2r)-2-amino-3-naphthalen-2-ylpropanoyl]amino]-16-[(4-hydroxyphenyl)methyl]-13-(1h-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17-p Chemical compound C([C@H]1C(=O)N[C@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(N[C@@H](CSSC[C@@H](C(=O)N1)NC(=O)[C@H](N)CC=1C=C2C=CC=CC2=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)=O)C(C)C)C1=CC=C(O)C=C1 PUDHBTGHUJUUFI-SCTWWAJVSA-N 0.000 claims 1
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims 1
- 239000005541 ACE inhibitor Substances 0.000 claims 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims 1
- 229940127291 Calcium channel antagonist Drugs 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 1
- 102000007625 Hirudins Human genes 0.000 claims 1
- 108010007267 Hirudins Proteins 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 239000004952 Polyamide Substances 0.000 claims 1
- 229920002732 Polyanhydride Polymers 0.000 claims 1
- 239000004721 Polyphenylene oxide Substances 0.000 claims 1
- 229920000388 Polyphosphate Polymers 0.000 claims 1
- 229920002396 Polyurea Polymers 0.000 claims 1
- 229960001138 acetylsalicylic acid Drugs 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 239000002870 angiogenesis inducing agent Substances 0.000 claims 1
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 230000000340 anti-metabolite Effects 0.000 claims 1
- 230000001028 anti-proliverative effect Effects 0.000 claims 1
- 229940127219 anticoagulant drug Drugs 0.000 claims 1
- 239000002256 antimetabolite Substances 0.000 claims 1
- 229940100197 antimetabolite Drugs 0.000 claims 1
- 239000003080 antimitotic agent Substances 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 229940127218 antiplatelet drug Drugs 0.000 claims 1
- 229960004676 antithrombotic agent Drugs 0.000 claims 1
- 229960002537 betamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 claims 1
- 239000000480 calcium channel blocker Substances 0.000 claims 1
- 239000000801 calcium channel stimulating agent Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 1
- 229960003957 dexamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- 239000003862 glucocorticoid Substances 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 229960002897 heparin Drugs 0.000 claims 1
- 229920000669 heparin Polymers 0.000 claims 1
- 229940006607 hirudin Drugs 0.000 claims 1
- WQPDUTSPKFMPDP-OUMQNGNKSA-N hirudin Chemical compound C([C@@H](C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC(OS(O)(=O)=O)=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]1NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@H](C(NCC(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N2)=O)CSSC1)C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=2C=CC(O)=CC=2)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)C(C)C)[C@@H](C)O)CSSC1)C(C)C)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 WQPDUTSPKFMPDP-OUMQNGNKSA-N 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 229960000448 lactic acid Drugs 0.000 claims 1
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 claims 1
- 229960002437 lanreotide Drugs 0.000 claims 1
- 108010021336 lanreotide Proteins 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- UQGPCEVQKLOLLM-UHFFFAOYSA-N pentaneperoxoic acid Chemical compound CCCCC(=O)OO UQGPCEVQKLOLLM-UHFFFAOYSA-N 0.000 claims 1
- 229920000118 poly(D-lactic acid) Polymers 0.000 claims 1
- 229920000218 poly(hydroxyvalerate) Polymers 0.000 claims 1
- 229920000747 poly(lactic acid) Polymers 0.000 claims 1
- 229920002627 poly(phosphazenes) Polymers 0.000 claims 1
- 229920002647 polyamide Polymers 0.000 claims 1
- 229920000768 polyamine Polymers 0.000 claims 1
- 229920001610 polycaprolactone Polymers 0.000 claims 1
- 239000004632 polycaprolactone Substances 0.000 claims 1
- 229920000728 polyester Polymers 0.000 claims 1
- 229920000570 polyether Polymers 0.000 claims 1
- 229920002959 polymer blend Polymers 0.000 claims 1
- 239000001205 polyphosphate Substances 0.000 claims 1
- 235000011176 polyphosphates Nutrition 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 229920002635 polyurethane Polymers 0.000 claims 1
- 239000004814 polyurethane Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 229960001295 tocopherol Drugs 0.000 claims 1
- 229930003799 tocopherol Natural products 0.000 claims 1
- 235000010384 tocopherol Nutrition 0.000 claims 1
- 239000011732 tocopherol Substances 0.000 claims 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/740,805 US20050149172A1 (en) | 2003-12-22 | 2003-12-22 | Minimal injury resorbable stent |
| PCT/US2004/040369 WO2005065582A1 (en) | 2003-12-22 | 2004-12-02 | Minimal injury resorbable stent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007515250A JP2007515250A (ja) | 2007-06-14 |
| JP2007515250A5 true JP2007515250A5 (https=) | 2008-01-31 |
Family
ID=34710514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006547035A Abandoned JP2007515250A (ja) | 2003-12-22 | 2004-12-02 | 微小損傷性の再吸収性ステント |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20050149172A1 (https=) |
| EP (1) | EP1703860A1 (https=) |
| JP (1) | JP2007515250A (https=) |
| WO (1) | WO2005065582A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005058777A (ja) * | 2003-08-18 | 2005-03-10 | Medtronic Vascular Inc | マルチブロックコポリマーからつくられた高弾性、高強度の膨張バルーン |
| US7731890B2 (en) | 2006-06-15 | 2010-06-08 | Advanced Cardiovascular Systems, Inc. | Methods of fabricating stents with enhanced fracture toughness |
| US9517149B2 (en) | 2004-07-26 | 2016-12-13 | Abbott Cardiovascular Systems Inc. | Biodegradable stent with enhanced fracture toughness |
| US8747878B2 (en) * | 2006-04-28 | 2014-06-10 | Advanced Cardiovascular Systems, Inc. | Method of fabricating an implantable medical device by controlling crystalline structure |
| US8747879B2 (en) | 2006-04-28 | 2014-06-10 | Advanced Cardiovascular Systems, Inc. | Method of fabricating an implantable medical device to reduce chance of late inflammatory response |
| US7971333B2 (en) | 2006-05-30 | 2011-07-05 | Advanced Cardiovascular Systems, Inc. | Manufacturing process for polymetric stents |
| DE602007009045D1 (de) * | 2006-01-05 | 2010-10-21 | Med Inst Inc | Zein-beschichtete medizinische vorrichtung |
| US20070162110A1 (en) * | 2006-01-06 | 2007-07-12 | Vipul Bhupendra Dave | Bioabsorbable drug delivery devices |
| US20070158880A1 (en) * | 2006-01-06 | 2007-07-12 | Vipul Bhupendra Dave | Methods of making bioabsorbable drug delivery devices comprised of solvent cast tubes |
| US20070160672A1 (en) * | 2006-01-06 | 2007-07-12 | Vipul Bhupendra Dave | Methods of making bioabsorbable drug delivery devices comprised of solvent cast films |
| US20070200271A1 (en) * | 2006-02-24 | 2007-08-30 | Vipul Dave | Implantable device prepared from melt processing |
| US20070200268A1 (en) * | 2006-02-24 | 2007-08-30 | Vipul Dave | Implantable device prepared from solution processing |
| AU2007249229B2 (en) * | 2006-05-12 | 2013-05-23 | Cardinal Health 529, Llc | Balloon expandable bioabsorbable drug eluting flexible stent |
| US9173733B1 (en) | 2006-08-21 | 2015-11-03 | Abbott Cardiovascular Systems Inc. | Tracheobronchial implantable medical device and methods of use |
| US20080051702A1 (en) * | 2006-08-24 | 2008-02-28 | Herrmann Robert A | Therapeutic agent delivery for the treatment of asthma via implantable and insertable medical devices |
| EP2214747A2 (en) * | 2007-11-20 | 2010-08-11 | Cook Incorporated | Controlled drug delivery using a zein layer modified with levulinic acid |
| US7972373B2 (en) * | 2007-12-19 | 2011-07-05 | Advanced Technologies And Regenerative Medicine, Llc | Balloon expandable bioabsorbable stent with a single stress concentration region interconnecting adjacent struts |
| US8802126B2 (en) * | 2008-06-30 | 2014-08-12 | Abbott Cardiovascular Systems Inc. | Polyester implantable medical device with controlled in vivo biodegradability |
| DE102008040791A1 (de) * | 2008-07-28 | 2010-02-04 | Biotronik Vi Patent Ag | Endoprothese und Verfahren zur Herstellung derselben |
| US20100244304A1 (en) * | 2009-03-31 | 2010-09-30 | Yunbing Wang | Stents fabricated from a sheet with increased strength, modulus and fracture toughness |
| US8679394B2 (en) | 2010-06-10 | 2014-03-25 | Abbott Cardiovascular Systems Inc. | Laser system and processing conditions for manufacturing bioabsorbable stents |
| WO2013068597A1 (de) * | 2011-11-12 | 2013-05-16 | Anke Domaske | Verfahren zur herstellung eines milchprotein-kunststoffes (mp - kunststoff) |
| GB2512016A (en) | 2012-09-24 | 2014-09-24 | Arterius Ltd | Methods |
| US9717609B2 (en) | 2013-08-01 | 2017-08-01 | Abbott Cardiovascular Systems Inc. | Variable stiffness stent |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3797499A (en) * | 1970-05-13 | 1974-03-19 | Ethicon Inc | Polylactide fabric graphs for surgical implantation |
| US4475972A (en) * | 1981-10-01 | 1984-10-09 | Ontario Research Foundation | Implantable material |
| US5110852A (en) * | 1982-07-16 | 1992-05-05 | Rijksuniversiteit Te Groningen | Filament material polylactide mixtures |
| FI85223C (fi) * | 1988-11-10 | 1992-03-25 | Biocon Oy | Biodegraderande kirurgiska implant och medel. |
| US5545208A (en) * | 1990-02-28 | 1996-08-13 | Medtronic, Inc. | Intralumenal drug eluting prosthesis |
| US5290494A (en) * | 1990-03-05 | 1994-03-01 | Board Of Regents, The University Of Texas System | Process of making a resorbable implantation device |
| US5500013A (en) * | 1991-10-04 | 1996-03-19 | Scimed Life Systems, Inc. | Biodegradable drug delivery vascular stent |
| WO1994021196A2 (en) * | 1993-03-18 | 1994-09-29 | C.R. Bard, Inc. | Endovascular stents |
| US6093200A (en) * | 1994-02-10 | 2000-07-25 | United States Surgical | Composite bioabsorbable materials and surgical articles made therefrom |
| US6245103B1 (en) * | 1997-08-01 | 2001-06-12 | Schneider (Usa) Inc | Bioabsorbable self-expanding stent |
| US6156062A (en) * | 1997-12-03 | 2000-12-05 | Ave Connaught | Helically wrapped interlocking stent |
| US6626939B1 (en) * | 1997-12-18 | 2003-09-30 | Boston Scientific Scimed, Inc. | Stent-graft with bioabsorbable structural support |
| US6147135A (en) * | 1998-12-31 | 2000-11-14 | Ethicon, Inc. | Fabrication of biocompatible polymeric composites |
| US6363697B1 (en) * | 2000-11-30 | 2002-04-02 | Richard Allen Shapiro | Foal weaning gear |
| US6719935B2 (en) * | 2001-01-05 | 2004-04-13 | Howmedica Osteonics Corp. | Process for forming bioabsorbable implants |
| US7572287B2 (en) * | 2001-10-25 | 2009-08-11 | Boston Scientific Scimed, Inc. | Balloon expandable polymer stent with reduced elastic recoil |
-
2003
- 2003-12-22 US US10/740,805 patent/US20050149172A1/en not_active Abandoned
-
2004
- 2004-12-02 JP JP2006547035A patent/JP2007515250A/ja not_active Abandoned
- 2004-12-02 EP EP04812808A patent/EP1703860A1/en not_active Withdrawn
- 2004-12-02 WO PCT/US2004/040369 patent/WO2005065582A1/en not_active Ceased
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