JP2007502638A5 - - Google Patents
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- Publication number
- JP2007502638A5 JP2007502638A5 JP2006523682A JP2006523682A JP2007502638A5 JP 2007502638 A5 JP2007502638 A5 JP 2007502638A5 JP 2006523682 A JP2006523682 A JP 2006523682A JP 2006523682 A JP2006523682 A JP 2006523682A JP 2007502638 A5 JP2007502638 A5 JP 2007502638A5
- Authority
- JP
- Japan
- Prior art keywords
- coating
- compound
- carrier
- ratio
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 18
- 239000011248 coating agent Substances 0.000 claims 15
- 238000000576 coating method Methods 0.000 claims 15
- 239000008199 coating composition Substances 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 9
- 238000000034 method Methods 0.000 claims 6
- 239000013543 active substance Substances 0.000 claims 4
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 3
- 229960003957 dexamethasone Drugs 0.000 claims 3
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 claims 3
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 claims 3
- 229960002930 sirolimus Drugs 0.000 claims 3
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims 2
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical group CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims 2
- 125000003342 alkenyl group Chemical group 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000000304 alkynyl group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- CBECDWUDYQOTSW-UHFFFAOYSA-N 2-ethylbut-3-enal Chemical group CCC(C=C)C=O CBECDWUDYQOTSW-UHFFFAOYSA-N 0.000 claims 1
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical group OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 claims 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical group C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 1
- 125000004036 acetal group Chemical group 0.000 claims 1
- 229960005309 estradiol Drugs 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 229920006002 poly(vinyl butyral-co-vinyl alcohol-co-vinyl acetate) Polymers 0.000 claims 1
- 229940074982 poly(vinylpyrrolidone-co-vinyl-acetate) Drugs 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0319461A GB0319461D0 (en) | 2003-08-19 | 2003-08-19 | Polymers for controlled drug release |
| GB0319461.0 | 2003-08-19 | ||
| GB0325060A GB0325060D0 (en) | 2003-10-27 | 2003-10-27 | Drug release system |
| GB0325060.2 | 2003-10-27 | ||
| PCT/GB2004/003547 WO2005018696A1 (en) | 2003-08-19 | 2004-08-18 | Polymeric drug release system for medical devices |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007502638A JP2007502638A (ja) | 2007-02-15 |
| JP2007502638A5 true JP2007502638A5 (enExample) | 2007-10-11 |
| JP4732346B2 JP4732346B2 (ja) | 2011-07-27 |
Family
ID=34219617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006523682A Expired - Fee Related JP4732346B2 (ja) | 2003-08-19 | 2004-08-18 | 医療機器用の高分子薬剤溶出システム |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060286139A1 (enExample) |
| EP (1) | EP1656165B1 (enExample) |
| JP (1) | JP4732346B2 (enExample) |
| AT (1) | ATE417637T1 (enExample) |
| AU (1) | AU2004266484B2 (enExample) |
| CA (1) | CA2534039A1 (enExample) |
| DE (1) | DE602004018509D1 (enExample) |
| WO (1) | WO2005018696A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090062909A1 (en) | 2005-07-15 | 2009-03-05 | Micell Technologies, Inc. | Stent with polymer coating containing amorphous rapamycin |
| GB0607189D0 (en) * | 2006-04-10 | 2006-05-17 | Polybiomed Ltd | interleukin IL 1ra composition |
| KR101226256B1 (ko) * | 2006-07-03 | 2013-01-25 | 헤모텍 아게 | 혈관의 영구 개방을 위한 활성 물질 방출용 의료 제품, 그의 제조 방법 및 용도 |
| CN101711137B (zh) | 2007-01-08 | 2014-10-22 | 米歇尔技术公司 | 具有可生物降解层的支架 |
| US11426494B2 (en) | 2007-01-08 | 2022-08-30 | MT Acquisition Holdings LLC | Stents having biodegradable layers |
| EP2121106A2 (en) | 2007-01-30 | 2009-11-25 | Boston Scientific Limited | Local delivery of therapeutic agent to heart valves |
| US20090074831A1 (en) * | 2007-09-18 | 2009-03-19 | Robert Falotico | LOCAL VASCULAR DELIVERY OF mTOR INHIBITORS IN COMBINATION WITH PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR STIMULATORS |
| FR2927813B1 (fr) * | 2008-02-21 | 2017-07-21 | Hexacath | Dispositif medical implantable sur une couche de protection/retention d'un agent actif ou medicament, notamment hydrosoluble |
| EA020655B1 (ru) | 2008-04-17 | 2014-12-30 | Миселл Текнолоджиз, Инк. | Стенты, имеющие биорассасывающиеся слои |
| CA2730995C (en) | 2008-07-17 | 2016-11-22 | Micell Technologies, Inc. | Drug delivery medical device |
| US9510856B2 (en) | 2008-07-17 | 2016-12-06 | Micell Technologies, Inc. | Drug delivery medical device |
| DE102008034826A1 (de) * | 2008-07-22 | 2010-01-28 | Alexander Rübben | Verfahren zur Erzeugung einer bioaktiven Oberfläche auf dem Ballon eines Ballonkatheters |
| WO2010075298A2 (en) * | 2008-12-23 | 2010-07-01 | Surmodics Pharmaceuticals, Inc. | Implantable composites and compositions comprising releasable bioactive agents |
| CN102481195B (zh) | 2009-04-01 | 2015-03-25 | 米歇尔技术公司 | 涂覆支架 |
| EP2335745B1 (de) * | 2009-12-21 | 2017-11-22 | Biotronik VI Patent AG | Implantat mit Beschichtung |
| EP2531140B1 (en) | 2010-02-02 | 2017-11-01 | Micell Technologies, Inc. | Stent and stent delivery system with improved deliverability |
| EP2560576B1 (en) | 2010-04-22 | 2018-07-18 | Micell Technologies, Inc. | Stents and other devices having extracellular matrix coating |
| CA2805631C (en) | 2010-07-16 | 2018-07-31 | Micell Technologies, Inc. | Drug delivery medical device |
| WO2013012689A1 (en) | 2011-07-15 | 2013-01-24 | Micell Technologies, Inc. | Drug delivery medical device |
| US10188772B2 (en) | 2011-10-18 | 2019-01-29 | Micell Technologies, Inc. | Drug delivery medical device |
| US11039943B2 (en) | 2013-03-12 | 2021-06-22 | Micell Technologies, Inc. | Bioabsorbable biomedical implants |
| CA2912387C (en) | 2013-05-15 | 2019-04-16 | Micell Technologies, Inc. | Bioabsorbable biomedical implants |
| KR102387358B1 (ko) * | 2018-05-17 | 2022-04-14 | 히타치 긴조쿠 가부시키가이샤 | 케이블 및 의료용 중공관 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU190619B (en) * | 1983-11-11 | 1986-09-29 | Bezzegh,Denes,Hu | Process for producing tablets with controlled dissolution of active ingredients |
| CA1229354A (en) * | 1984-03-01 | 1987-11-17 | David C. Greenspan | Biologically active glass compositions for bonding to alloys |
| USRE34990E (en) * | 1986-08-07 | 1995-07-04 | Ciba-Geigy Corporation | Oral therapeutic system having systemic action |
| US5026771A (en) * | 1989-08-03 | 1991-06-25 | Monsanto Company | Coating compositions containing ethylenically unsaturated carbamates |
| US5324615A (en) * | 1993-08-13 | 1994-06-28 | Xerox Corporation | Method of making electrostatographic imaging members containing vanadyl phthalocyanine |
| US5637113A (en) * | 1994-12-13 | 1997-06-10 | Advanced Cardiovascular Systems, Inc. | Polymer film for wrapping a stent structure |
| DE69625799T2 (de) * | 1995-02-01 | 2003-10-23 | Schneider (Usa) Inc., Plymouth | Verfahren zur hydrophilisierung von hydrophoben polymeren |
| US5674513A (en) * | 1996-02-20 | 1997-10-07 | Viro-Kote, Inc. | Anti-bacterial/anti-viral coatings, coating process and parameters thereof |
| GB2325934A (en) * | 1997-06-03 | 1998-12-09 | Polybiomed Ltd | Treating metal surfaces to enhance bio-compatibility and/or physical characteristics |
| US6110483A (en) * | 1997-06-23 | 2000-08-29 | Sts Biopolymers, Inc. | Adherent, flexible hydrogel and medicated coatings |
| US8029561B1 (en) * | 2000-05-12 | 2011-10-04 | Cordis Corporation | Drug combination useful for prevention of restenosis |
| US6254634B1 (en) * | 1998-06-10 | 2001-07-03 | Surmodics, Inc. | Coating compositions |
| US20020087184A1 (en) * | 1998-06-18 | 2002-07-04 | Eder Joseph C. | Water-soluble coating for bioactive devices |
| US6340465B1 (en) * | 1999-04-12 | 2002-01-22 | Edwards Lifesciences Corp. | Lubricious coatings for medical devices |
| US6613082B2 (en) * | 2000-03-13 | 2003-09-02 | Jun Yang | Stent having cover with drug delivery capability |
| ES2391763T3 (es) * | 2000-04-07 | 2012-11-29 | Collagen Matrix, Inc. | Dispositivo de embolización |
| US6746773B2 (en) * | 2000-09-29 | 2004-06-08 | Ethicon, Inc. | Coatings for medical devices |
| GB0100760D0 (en) * | 2001-01-11 | 2001-02-21 | Biocompatibles Ltd | Drug delivery from stents |
| DE10107795B4 (de) * | 2001-02-13 | 2014-05-15 | Berlex Ag | Gefäßstütze mit einem Grundkörper, Verfahren zur Herstellung der Gefäßstütze, Vorrichtung zur Beschichtung der Gefäßstütze |
| WO2002074194A2 (en) * | 2001-03-16 | 2002-09-26 | Sts Biopolymers, Inc. | Stent with medicated multi-layer hydrid polymer coating |
| US6676987B2 (en) * | 2001-07-02 | 2004-01-13 | Scimed Life Systems, Inc. | Coating a medical appliance with a bubble jet printing head |
| GB0122393D0 (en) * | 2001-09-17 | 2001-11-07 | Polybiomed Ltd | Treating metal surfaces to enhance bio-compatibility |
| US7294329B1 (en) * | 2002-07-18 | 2007-11-13 | Advanced Cardiovascular Systems, Inc. | Poly(vinyl acetal) coatings for implantable medical devices |
| EP1594397B1 (en) * | 2003-02-20 | 2011-10-26 | Cook Medical Technologies LLC | Medical device with adherent coating and method for preparing same |
| AU2004237774B2 (en) * | 2003-05-02 | 2009-09-10 | Surmodics, Inc. | Implantable controlled release bioactive agent delivery device |
-
2004
- 2004-08-18 DE DE602004018509T patent/DE602004018509D1/de not_active Expired - Lifetime
- 2004-08-18 CA CA002534039A patent/CA2534039A1/en not_active Abandoned
- 2004-08-18 AU AU2004266484A patent/AU2004266484B2/en not_active Ceased
- 2004-08-18 US US10/567,979 patent/US20060286139A1/en not_active Abandoned
- 2004-08-18 EP EP04768107A patent/EP1656165B1/en not_active Expired - Lifetime
- 2004-08-18 JP JP2006523682A patent/JP4732346B2/ja not_active Expired - Fee Related
- 2004-08-18 WO PCT/GB2004/003547 patent/WO2005018696A1/en not_active Ceased
- 2004-08-18 AT AT04768107T patent/ATE417637T1/de not_active IP Right Cessation
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