JP2007260038A - Measuring method of number of hair strands and evaluation method of effect of hair growing agent - Google Patents
Measuring method of number of hair strands and evaluation method of effect of hair growing agent Download PDFInfo
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- JP2007260038A JP2007260038A JP2006087528A JP2006087528A JP2007260038A JP 2007260038 A JP2007260038 A JP 2007260038A JP 2006087528 A JP2006087528 A JP 2006087528A JP 2006087528 A JP2006087528 A JP 2006087528A JP 2007260038 A JP2007260038 A JP 2007260038A
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- 210000004209 hair Anatomy 0.000 title claims abstract description 109
- 238000000034 method Methods 0.000 title claims abstract description 40
- 238000011156 evaluation Methods 0.000 title claims abstract description 6
- 238000005259 measurement Methods 0.000 claims abstract description 58
- 230000003779 hair growth Effects 0.000 claims description 25
- 238000000691 measurement method Methods 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 description 21
- 210000003128 head Anatomy 0.000 description 8
- 210000004761 scalp Anatomy 0.000 description 5
- 239000000049 pigment Substances 0.000 description 4
- ZFMITUMMTDLWHR-UHFFFAOYSA-N Minoxidil Chemical compound NC1=[N+]([O-])C(N)=CC(N2CCCCC2)=N1 ZFMITUMMTDLWHR-UHFFFAOYSA-N 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000006210 lotion Substances 0.000 description 3
- 229960003632 minoxidil Drugs 0.000 description 3
- 201000004384 Alopecia Diseases 0.000 description 2
- 231100000360 alopecia Toxicity 0.000 description 2
- 210000004709 eyebrow Anatomy 0.000 description 2
- 238000010191 image analysis Methods 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 238000009966 trimming Methods 0.000 description 1
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Abstract
Description
本発明は、発毛剤の効果を評価する際などに有用な毛髪数の計測方法および発毛剤の効果の評価方法に関する。 The present invention relates to a method for measuring the number of hairs useful for evaluating the effect of a hair growth agent, and a method for evaluating the effect of a hair growth agent.
従来、発毛剤の効果を評価する際などに行われる毛髪数の計測方法としては、例えば、非特許文献１に記載されている下記の（１）〜（７）の工程を順次実行するようなものが知られている。
（１）計測対象者の頭部の選定部位に１．２ｃｍ×１．２ｃｍの四角形の穴の開いたプレートをあて、開口部からはみ出た選定部位に生えている毛髪を適当な長さに必要に応じてカットする工程
（２）プレートを外して毛髪をさらに０．５ｍｍ〜１ｍｍの長さにトリミングする工程
（３）トリミングの済んだ選定部位に１ｃｍ×１ｃｍの四角形の穴の開いたプレートをあて、対角線上の２点を頭皮に入れ墨する工程
（４）マクロレンズを装着したカメラで選定部位を撮影する工程
（５）写真を拡大プリントし、その上に透明なフィルムシートを載せ、写っている入れ墨の２点を対角とした四角形を描く工程
（６）描いた四角形（即ち面積が１ｃｍ２の計測部位）の中にある色素を有する毛髪を非軟毛としてその根元に油状のマジックでドットを打ってドットマップを作成する工程
（７）作成したドットマップのドットの数を画像解析・計測ソフトウェアを用いて自動集計する工程
Conventionally, as a method for measuring the number of hairs performed when evaluating the effect of a hair growth agent, for example, the following steps (1) to (7) described in Non-Patent Document 1 are sequentially performed. What is known.
(1) A plate with a 1.2cm x 1.2cm square hole is applied to the selected part of the measurement subject's head, and the hair growing on the selected part protruding from the opening is required to have an appropriate length. (2) Removing the plate and trimming the hair to a length of 0.5 mm to 1 mm (3) A plate having a 1 cm × 1 cm square hole at the trimmed selected part The process of tattooing two points on the diagonal line on the scalp (4) The process of photographing the selected part with a camera equipped with a macro lens (5) The photograph is enlarged and a transparent film sheet is placed on it dot oil magic hair with a dye to the root as a non-fluff which is in the process of drawing a rectangle with diagonal two points (6) drawn rectangle (i.e. measurement site area 1 cm 2) of the tattoo are A step of rolled using a number of dots of the step (7) dot map created to create a dot map hit the image analysis and measurement software
しかしながら、上記のような毛髪数の計測方法は、手間がかかるものであり、また、色素の有無を判断しなければならないことから計測実行者の主観的意思が計測結果に反映されてしまうことで客観性に欠ける場合が否定できず、さらに、計測対象者に頭皮に入れ墨を入れるといった負担をかけてしまうことになる。
そこで本発明は、簡易であり正確かつ客観的で、計測対象者に肉体的な負担をかけるといったことがない毛髪数の計測方法および発毛剤の効果の評価方法を提供することを目的とする。 Therefore, an object of the present invention is to provide a method for measuring the number of hairs and a method for evaluating the effect of a hair growth agent that are simple, accurate and objective, and do not impose a physical burden on the measurement subject. .
上記の点に鑑みてなされた本発明の毛髪数の計測方法は、請求項１記載の通り、下記の（１）〜（５）の工程を順次実行することを特徴とする。
（１）計測対象者の頭部に対して計測部位とする部位を含む部位を選定する工程
（２）選定部位に生えている毛髪を０．５ｍｍ〜３ｍｍの長さに必要に応じてカットする工程
（３）選定部位をデジタルカメラで撮影することで、その画像データを取得する工程
（４）画像データをコンピュータに取り込んで画面上に表示し、画面上に表示した画像の中から所定面積の計測部位を決定し、画面上で計測部位に生えている毛髪１本一本に対してタグマークを付与する工程
（５）画面上に付与したタグマークを自動集計することで毛髪数の計測を行う工程
また、請求項２記載の計測方法は、請求項１記載の計測方法において、基準太さの寸法の画像を計測部位の画像と同じ倍率で画面上に表示し、計測部位に生えている毛髪の太さを基準太さと比較し、基準太さよりも細い場合と同じ太さ以上の場合とで付与するタグマークの種類を変え、異なるタグマークを別々に自動集計することで、毛髪の種類を太さによって２種類に分類し、それぞれの毛髪数の計測を別々に行うことを特徴とする。
また、請求項３記載の計測方法は、請求項２記載の計測方法において、基準太さを４０μｍに設定し、基準太さよりも細い毛髪を軟毛、基準太さと同じ太さ以上の毛髪を非軟毛に分類し、それぞれに対して付与したタグマークを別々に自動集計することで、軟毛の毛髪数の計測と非軟毛の毛髪数の計測を別々に行うことを特徴とする。
また、請求項４記載の計測方法は、請求項１乃至３のいずれかに記載の計測方法において、計測部位の面積を０．８ｃｍ２〜１．２ｃｍ２とすることを特徴とする。
また、本発明の発毛剤の効果の評価方法は、請求項５記載の通り、発毛剤の投与対象者に対して発毛剤の投与スケジュールのいずれかの１点において下記の（１）〜（５）の工程を順次実行することで毛髪数の計測を行った後、先に毛髪数の計測を行った計測部位の毛髪数の計数を再び行い、両者の計測結果によって明らかになった毛髪数の変化の程度に基づいて効果判断を行うことを特徴とする。
（１）発毛剤の投与対象者の頭部に対して計測部位とする部位を含む部位を選定する工程
（２）選定部位に生えている毛髪を０．５ｍｍ〜３ｍｍの長さに必要に応じてカットする工程
（３）選定部位をデジタルカメラで撮影することで、その画像データを取得する工程
（４）画像データをコンピュータに取り込んで画面上に表示し、画面上に表示した画像の中から所定面積の計測部位を決定し、画面上で計測部位に生えている毛髪１本一本に対してタグマークを付与する工程
（５）画面上に付与したタグマークを自動集計することで毛髪数の計測を行う工程
The method for measuring the number of hairs of the present invention made in view of the above points is characterized in that the following steps (1) to (5) are sequentially executed as described in claim 1.
(1) Step of selecting a part including a part to be measured with respect to the measurement subject's head (2) Cutting hair growing on the selected part to a length of 0.5 mm to 3 mm as necessary Step (3) Step (4) Acquire the image data by photographing the selected part with a digital camera. (4) Capture the image data into a computer and display it on the screen. From the image displayed on the screen, a predetermined area is obtained. The measurement part is decided, and the tag mark is given to each hair that grows on the measurement part on the screen. (5) The number of hairs is measured by automatically counting the tag marks given on the screen. The measuring method according to claim 2 is the measuring method according to claim 1, wherein the image of the reference thickness is displayed on the screen at the same magnification as the image of the measurement part and grows on the measurement part. Compare hair thickness with standard thickness However, by changing the type of tag mark to be applied depending on whether it is thinner than the standard thickness or the same thickness or more, and automatically counting different tag marks separately, the hair types are classified into two types according to the thickness. The number of hairs is measured separately.
Further, the measurement method according to claim 3 is the measurement method according to claim 2, wherein the reference thickness is set to 40 μm, the hair thinner than the reference thickness is soft hair, and the hair having the same thickness as the reference thickness is non-soft hair The number of soft hairs and the number of non-soft hairs are measured separately by automatically counting the tag marks assigned to each of them and separately counting them.
Also, measurement method of claim 4, wherein, in the measuring method according to any one of claims 1 to 3, the area of the measurement portion, characterized in that a 0.8cm 2 ~1.2cm 2.
Moreover, the evaluation method of the effect of the hair growth agent of this invention is the following (1) in any one of the administration schedules of a hair growth agent with respect to the subject of hair growth agent administration as described in Claim 5. After the number of hairs was measured by sequentially executing the steps (5) to (5), the number of hairs at the measurement site where the number of hairs was previously measured was counted again, and the results of both measurements revealed the results. The effect is judged based on the degree of change in the number of hairs.
(1) A step of selecting a site including a site to be measured with respect to the head of a person to whom a hair growth agent is administered (2) The hair growing on the selected site is required to have a length of 0.5 mm to 3 mm (3) Step of obtaining the image data by photographing the selected portion with a digital camera (4) Image data is captured on the computer and displayed on the screen, and the image displayed on the screen The measurement part of a predetermined area is determined from the step, and a tag mark is given to each hair that grows on the measurement part on the screen. (5) Hair is automatically counted by adding the tag marks given on the screen. The process of measuring the number
本発明によれば、簡易であり正確かつ客観的で、計測対象者に肉体的な負担をかけるといったことがない毛髪数の計測方法および発毛剤の効果の評価方法が提供される。 According to the present invention, there are provided a method for measuring the number of hairs and a method for evaluating the effects of hair growth agents, which are simple, accurate and objective, and do not impose a physical burden on the measurement subject.
以下、本発明の毛髪数の計測方法を工程毎に順を追って説明する。 Hereinafter, the method for measuring the number of hairs of the present invention will be described step by step.
工程（１）
まず、計測対象者の頭部に対して計測部位とする部位を含む部位を選定する。この工程は、発毛剤の効果を評価する際などにおいては、例えば、計測対象者（発毛剤の投与対象者）の頭部の脱毛部と有毛部の境界部分から行えばよい。
Process (1)
First, a part including a part to be measured with respect to the head of the measurement target is selected. This step may be performed, for example, from the boundary between the hair removal part and the hair part of the head of the measurement subject (the subject to whom the hair growth agent is administered) when evaluating the effect of the hair growth agent.
工程（２）
次に、選定部位に生えている毛髪を０．５ｍｍ〜３ｍｍの長さに必要に応じてカットする。この工程は、毛髪数の計測を正確に行うために重要な工程であり、例えば、計測部位の面積を０．８ｃｍ２〜１．２ｃｍ２とする場合、選定部位に１．５ｃｍ×１．５ｃｍ程度の四角形の穴の開いたプレートをあて、開口部からはみ出た毛髪をカットすることにより行えばよい。毛髪は１ｍｍ〜２ｍｍの長さにカットすることが望ましい。
Step (2)
Next, the hair growing on the selected part is cut to a length of 0.5 mm to 3 mm as necessary. This step is an important step in order to perform accurate measurements of the number of hairs, for example, if the area of the measurement portion and 0.8cm 2 ~1.2cm 2, 1.5cm × 1.5cm to selected sites What is necessary is just to cut the hair which protruded from the opening part by applying the plate with the hole of about a square. It is desirable to cut the hair to a length of 1 mm to 2 mm.
工程（３）
次に、選定部位をデジタルカメラで撮影することで、その画像データを取得する。この工程は、例えば、市販のマイクロスコープ（ＭＯＲＩＴＥＸ社製のコンピュータ一体型ＣＣＤカメラ付マイクロスコープシステムＭＳ−２０００ＲＳなど）を用い、一定倍率（１０倍〜２０倍が望ましい）で拡大撮影することにより行うことが望ましい。この際、カメラレンズと頭皮の距離を常に一定にするため、カメラの先端に接触ドームを接続し、接触ドームの先端を頭皮に垂直にあてた場合にカメラのピントがあうように設定して撮影することが望ましい（図１参照）。
Process (3)
Next, the selected part is imaged with a digital camera to acquire the image data. This step is performed, for example, by using a commercially available microscope (such as a microscope system MS-2000RS with a computer-integrated CCD camera manufactured by MORITEX, Inc.) at a constant magnification (preferably 10 to 20 times). It is desirable. At this time, in order to keep the distance between the camera lens and the scalp constant, a contact dome is connected to the tip of the camera, and the camera is set to focus when the tip of the contact dome is perpendicular to the scalp. It is desirable to do so (see FIG. 1).
工程（４）
次に、選定部位の画像データをコンピュータに取り込んで画面上に表示し、画面上に表示した画像の中から所定面積の計測部位を決定する（図２参照）。そして、画面上で計測部位に生えている毛髪１本一本に対してタグマークを付与する。計測効率や毛髪数の変化を正確に捉えることなどを鑑みれば、計測部位の面積は０．８ｃｍ２〜１．２ｃｍ２とすることが望ましい。画面上で計測部位に生えている毛髪１本一本に対してタグマークを付与する際、基準太さの寸法の画像を計測部位の画像と同じ倍率で画面上に表示し、計測部位に生えている毛髪の太さを基準太さと比較し、基準太さよりも細い場合と同じ太さ以上の場合とで付与するタグマークの種類を変え、異なるタグマークを別々に自動集計することで、毛髪の種類を太さによって２種類に分類し、それぞれの毛髪数の計測を別々に行うようにしてもよい（図３参照）。例えば、基準太さを４０μｍに設定し、基準太さよりも細い毛髪を軟毛（ｖｅｌｌｕｓ ｈａｉｒ，毛髪の種類：短くて細く色素のない毛髪である軟毛）、基準太さと同じ太さ以上の毛髪を非軟毛（ｎｏｎ−ｖｅｌｌｕｓ ｈａｉｒ，毛髪の種類：長くて太く色素のある毛髪である硬毛と中間の長さ・太さで色素のある毛髪である中間毛）に分類し、それぞれに対して付与したタグマークを別々に自動集計することで、軟毛の毛髪数の計測と非軟毛の毛髪数の計測を別々に行うことができる。なお、画像データをコンピュータに取り込む際には、デジタルカメラから直接取り込むようにしてもよいし、いったん画像データをＣＤ−Ｒなどの記録媒体に保存し、記録媒体から取り込むようにしてもよい。
Step (4)
Next, the image data of the selected part is taken into a computer and displayed on the screen, and a measurement part having a predetermined area is determined from the image displayed on the screen (see FIG. 2). Then, a tag mark is given to each hair growing on the measurement site on the screen. In view of such accurately grasp that the change in the measurement efficiency and speed hair, the area of the measurement region is preferably set to 0.8cm 2 ~1.2cm 2. When a tag mark is attached to each hair that grows on the measurement site on the screen, an image of the size of the reference thickness is displayed on the screen at the same magnification as the image of the measurement site, and grows on the measurement site. By comparing the thickness of the hair being compared with the reference thickness, changing the type of tag mark to be applied depending on whether it is thinner than the reference thickness or the same thickness or more, and automatically counting different tag marks separately, the hair May be classified into two types according to thickness, and the number of hairs may be measured separately (see FIG. 3). For example, if the reference thickness is set to 40 μm, hair thinner than the reference thickness is soft (vellus hair, hair type: soft hair that is short, thin, and has no pigment), and hair that is equal to or larger than the reference thickness is not covered Classified into soft hair (non-bell hair, type of hair: long and thick hair with pigment, and intermediate hair with pigment in the middle length and thickness) and applied to each By automatically counting the tag marks separately, the number of soft hairs and the number of non-soft hairs can be measured separately. When capturing image data into a computer, the image data may be directly captured from a digital camera, or the image data may be once stored in a recording medium such as a CD-R and captured from the recording medium.
工程（５）
最後に、画面上に付与したタグマークを自動集計することで毛髪数の計測を行う。タグマークの自動集計は、例えば、市販の画像解析・計測ソフトウェア（Ｍｅｄｉａ Ｃｙｂｅｒｎｅｔｉｃｓ社製のＩｍａｇｅ−Ｐｒｏ−ＰＬＵＳ ｖｅｒ．４．０Ｊなど）を用いて行えばよい。
Process (5)
Finally, the number of hairs is measured by automatically counting the tag marks assigned on the screen. The automatic counting of tag marks may be performed using, for example, commercially available image analysis / measurement software (such as Image-Pro-PLUS ver. 4.0J manufactured by Media Cybernetics).
本発明の毛髪数の計測方法は、例えば、脱毛症の患者に対する既存発毛剤の効果を評価する場合や、新規な開発発毛剤の効果を評価する場合などに有用である。発毛剤の効果の評価は、まず、発毛剤の投与対象者に対して発毛剤の投与スケジュールのいずれかの１点（例えば発毛剤の投与開始時）において上記の（１）〜（５）の工程を順次実行することで毛髪数の計測を行い、その後、先に毛髪数の計測を行った計測部位の毛髪数の計数を再び行い、両者の計測結果によって明らかになった毛髪数の変化の程度に基づいて効果判断を行う。 The method for measuring the number of hairs of the present invention is useful, for example, when evaluating the effects of existing hair growth agents on alopecia patients or when evaluating the effects of newly developed hair growth agents. The evaluation of the effect of the hair growth agent is carried out by first evaluating the above-mentioned (1) to (1) to any one point of the hair growth agent administration schedule (for example, at the start of administration of the hair growth agent). The number of hairs is measured by sequentially executing the process of (5), and then the number of hairs at the measurement site where the number of hairs was previously measured is counted again, and the hair that is clarified by the measurement results of both The effect is judged based on the degree of change in the number.
後に行う先に毛髪数の計測を行った計測部位の毛髪数の計数は、発毛剤の投与対象者の頭部から計測部位を見つけ出して行う必要があるが、これは、例えば、次のようにして行うことができる。
（ａ）先の毛髪数の計測を行った際に計測部位の記録を行っておく。例えば、右耳から計測部位を経て左耳までを紐などで結び、右耳から計測部位までの距離を記録し、さらに、眉毛と眉毛の間の中心から計測部位までを紐などで結び、その距離を記録しておく。また、このような記録に加えて、計測部位が見えるように頭部全体の写真を撮影しておいてもよい。
（ｂ）後の毛髪数の計測を行う際、上記の記録や頭部全体の写真をもとに計測部位の大方の位置を特定する。
（２’）計測部位を含む部位に生えている毛髪を０．５ｍｍ〜３ｍｍの長さに必要に応じてカットする。
（３’）上記の部位をデジタルカメラで撮影することで、その画像データを取得する。
（４’）画像データをコンピュータに取り込んで画面上に表示し、画面上に表示した画像と先の毛髪数の計測を行った際の画像とを比較し、個々の毛髪の生え方や毛根の位置などを見比べてｈａｉｒ ｔｏ ｈａｉｒで一致させて画像の中から計測部位を特定する。その後、画面上で計測部位に生えている毛髪１本一本に対してタグマークを付与する。
（５’）画面上に付与したタグマークを自動集計することで毛髪数の計測を行う。
なお、上記の（２’）〜（５’）の操作は、計測部位の特定を除き、基本的に先に説明した工程（２）〜工程（５）と同様にして行えばよい。
It is necessary to find the measurement site from the head of the person to whom the hair growth agent is administered. Can be done.
(A) When the number of previous hairs is measured, the measurement site is recorded. For example, a string is connected from the right ear through the measurement site to the left ear, the distance from the right ear to the measurement site is recorded, and the center from the center between the eyebrows and the eyebrows to the measurement site is connected with a string. Record the distance. In addition to such recording, a photograph of the entire head may be taken so that the measurement site can be seen.
(B) When the number of subsequent hairs is measured, the position of the majority of the measurement site is specified based on the above-mentioned record and a photograph of the entire head.
(2 ′) The hair growing on the part including the measurement part is cut to a length of 0.5 mm to 3 mm as necessary.
(3 ′) The image data is acquired by photographing the above-described part with a digital camera.
(4 ') The image data is captured on a computer and displayed on the screen. The image displayed on the screen is compared with the image obtained when the number of hairs is measured, and the hair growth and roots of each hair are compared. The measurement part is identified from the image by comparing the position and the like and matching with the hair to hair. After that, a tag mark is given to each hair growing on the measurement site on the screen.
(5 ') The number of hairs is measured by automatically counting the tag marks given on the screen.
The operations (2 ′) to (5 ′) described above may be performed basically in the same manner as the steps (2) to (5) described above, except for specifying the measurement site.
対象として的確な脱毛症の患者を同意取得後に１％ミノキシジル投与群（１ｍｌ中に発毛剤の有効成分であるミノキシジルを１０ｍｇ含有するローション剤：ＴＭＳ群）およびプラセボ投与群（ミノキシジルを含有しないローション剤：ＰＢＯ群）に分け、２種類のローション剤のいずれかを各患者の脱毛している頭皮に１回１ｍｌ、１日２回、２４週間塗布した。
試験開始時および４週間毎に、本発明の手順に従って毛髪数の計測を行った。この際、選定部位に生えている毛髪は１ｍｍ〜２ｍｍの長さにカットした。選定部位の拡大撮影の倍率は１５倍とした。計測部位の面積は１ｃｍ２とした。毛髪数の計測は基準太さを４０μｍに設定し、太さが４０μｍよりも細い毛髪を軟毛、太さが４０μｍ以上の毛髪を非軟毛としてそれぞれの毛髪について行った。
試験開始から２４週間経過後の最終評価時における、試験開始時からの毛髪数の変化を平均値として表１に示した。なお、毛髪数計測データを採用できた患者はＴＭＳ群１２３名、ＰＢＯ群１２２名であった。
表１から明らかなように、本発明の方法によれば、発毛剤の効果を簡易に正確かつ客観的に評価できることがわかった。
1% minoxidil administration group (lotion preparation containing 10 mg of minoxidil, the active ingredient of hair growth agent in 1 ml: TMS group) and placebo administration group (lotion containing no minoxidil) after obtaining consent from patients with accurate alopecia as subjects Agent: PBO group) One of two types of lotions was applied to the scalp of each patient's hair after being applied 1 ml once a day twice a day for 24 weeks.
The number of hairs was measured according to the procedure of the present invention at the start of the test and every 4 weeks. At this time, the hair growing on the selected part was cut to a length of 1 mm to 2 mm. The magnification of the enlarged image of the selected part was 15 times. The area of the measurement site was 1 cm 2 . The number of hairs was measured for each hair with a reference thickness set to 40 μm, with hair thinner than 40 μm soft and hair having thickness of 40 μm or more as non-soft hair.
The change in the number of hairs from the start of the test at the final evaluation 24 weeks after the start of the test is shown in Table 1 as an average value. The number of patients who could adopt the hair count data was 123 in the TMS group and 122 in the PBO group.
As can be seen from Table 1, according to the method of the present invention, it was found that the effect of the hair growth agent can be easily and accurately evaluated objectively.
本発明は、簡易であり正確かつ客観的で、計測対象者に肉体的な負担をかけるといったことがない毛髪数の計測方法および発毛剤の効果の評価方法を提供することができる点において産業上の利用可能性を有する。 The present invention is industrial in that it can provide a method for measuring the number of hairs and a method for evaluating the effects of hair growth agents that are simple, accurate and objective, and do not impose a physical burden on the measurement subject. With the above applicability.
Claims (5)
（１）計測対象者の頭部に対して計測部位とする部位を含む部位を選定する工程
（２）選定部位に生えている毛髪を０．５ｍｍ〜３ｍｍの長さに必要に応じてカットする工程
（３）選定部位をデジタルカメラで撮影することで、その画像データを取得する工程
（４）画像データをコンピュータに取り込んで画面上に表示し、画面上に表示した画像の中から所定面積の計測部位を決定し、画面上で計測部位に生えている毛髪１本一本に対してタグマークを付与する工程
（５）画面上に付与したタグマークを自動集計することで毛髪数の計測を行う工程 A method for measuring the number of hairs, wherein the following steps (1) to (5) are sequentially performed.
(1) Step of selecting a part including a part to be measured with respect to the measurement subject's head (2) Cutting hair growing on the selected part to a length of 0.5 mm to 3 mm as necessary Step (3) Step (4) Acquire the image data by photographing the selected part with a digital camera. (4) Capture the image data into a computer and display it on the screen. From the image displayed on the screen, a predetermined area is obtained. The measurement part is decided, and the tag mark is given to each hair that grows on the measurement part on the screen. (5) The number of hairs is measured by automatically counting the tag marks given on the screen. Process to perform
（１）発毛剤の投与対象者の頭部に対して計測部位とする部位を含む部位を選定する工程
（２）選定部位に生えている毛髪を０．５ｍｍ〜３ｍｍの長さに必要に応じてカットする工程
（３）選定部位をデジタルカメラで撮影することで、その画像データを取得する工程
（４）画像データをコンピュータに取り込んで画面上に表示し、画面上に表示した画像の中から所定面積の計測部位を決定し、画面上で計測部位に生えている毛髪１本一本に対してタグマークを付与する工程
（５）画面上に付与したタグマークを自動集計することで毛髪数の計測を行う工程 A method for evaluating the effect of a hair growth agent, wherein the following steps (1) to (5) are sequentially performed at any one point of the hair growth agent administration schedule for a hair growth agent administration subject: After measuring the number of hairs, the number of hairs at the measurement site where the number of hairs was previously measured is counted again, and the effect is based on the degree of change in the number of hairs revealed by both measurement results. An evaluation method characterized by making a judgment.
(1) A step of selecting a site including a site to be measured with respect to the head of a person to whom a hair growth agent is administered (2) The hair growing on the selected site is required to have a length of 0.5 mm to 3 mm (3) Step of obtaining the image data by photographing the selected portion with a digital camera (4) Image data is captured on the computer and displayed on the screen, and the image displayed on the screen The measurement part of a predetermined area is determined from the step, and a tag mark is given to each hair that grows on the measurement part on the screen. (5) Hair is automatically counted by adding the tag marks given on the screen. The process of measuring the number
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| JP2010501288A (en) * | 2006-08-25 | 2010-01-21 | レストレーション ロボティクス，インク． | System and method for counting hair follicle units |
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| WO2021215749A1 (en) * | 2020-04-21 | 2021-10-28 | (주)에임즈 | Hair information provision method and device, and hair root analysis model generation method therefor |
| KR20210129955A (en) * | 2020-04-21 | 2021-10-29 | (주)에임즈 | Method of analyzing hair condition and apparatus and system of providing hair information |
| US11858154B2 (en) * | 2017-02-20 | 2024-01-02 | Koninklijke Philips N.V. | Operating a personal care device |
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| JP2010501288A (en) * | 2006-08-25 | 2010-01-21 | レストレーション ロボティクス，インク． | System and method for counting hair follicle units |
| JP2011024836A (en) * | 2009-07-27 | 2011-02-10 | Taisho Pharmaceutical Co Ltd | Method and device for specifying measurement or observation part of hair |
| US11858154B2 (en) * | 2017-02-20 | 2024-01-02 | Koninklijke Philips N.V. | Operating a personal care device |
| WO2021215749A1 (en) * | 2020-04-21 | 2021-10-28 | (주)에임즈 | Hair information provision method and device, and hair root analysis model generation method therefor |
| KR20210129955A (en) * | 2020-04-21 | 2021-10-29 | (주)에임즈 | Method of analyzing hair condition and apparatus and system of providing hair information |
| KR102329641B1 (en) * | 2020-04-21 | 2021-11-22 | (주)에임즈 | Method of analyzing hair condition and apparatus and system of providing hair information |
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