JP2007093356A5 - - Google Patents

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JP2007093356A5
JP2007093356A5 JP2005282291A JP2005282291A JP2007093356A5 JP 2007093356 A5 JP2007093356 A5 JP 2007093356A5 JP 2005282291 A JP2005282291 A JP 2005282291A JP 2005282291 A JP2005282291 A JP 2005282291A JP 2007093356 A5 JP2007093356 A5 JP 2007093356A5
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blood
imaging
possibility
abnormal
specimen
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Priority to US11/528,757 priority patent/US7796797B2/en
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検体の血液標本の血液像を撮像する撮像部と、
前記検体中における異常細胞の出現の可能性を示す異常細胞情報を含む血液分析情報を取得する取得手段と、
前記取得手段によって取得された前記血液分析情報が、異常細胞の出現の可能性を示していない場合には第１撮像条件で撮像し、異常細胞の出現の可能性を示している場合には第２撮像条件で撮像するように前記撮像部を制御する制御部と、
を備えた血液撮像装置。 An imaging unit for imaging a blood image of a blood sample of the specimen;
Acquisition means for acquiring blood analysis information including abnormal cell information indicating the possibility of appearance of abnormal cells in the specimen;
When the blood analysis information acquired by the acquisition means does not indicate the possibility of the appearance of abnormal cells, it is imaged under the first imaging condition, and when the blood analysis information indicates the possibility of the appearance of abnormal cells, A control unit that controls the imaging unit to perform imaging under two imaging conditions;
A blood imaging apparatus comprising: 前記取得手段は、有核異常血球の出現の可能性を示す有核異常血球情報を含む血液分析情報を取得するものである請求項１記載の血液撮像装置。   The blood imaging apparatus according to claim 1, wherein the acquisition unit acquires blood analysis information including nucleated abnormal blood cell information indicating a possibility of appearance of abnormal nucleated blood cells. 前記有核異常血球情報が、幼若白血球の出現の可能性を示す幼若白血球情報、異型リンパ球の出現の可能性を示す異型リンパ球情報、及び有核赤血球の出現の可能性を示す有核赤血球情報から少なくとも１つ選択される請求項２記載の血液撮像装置。   The nucleated abnormal blood cell information includes immature leukocyte information indicating the possibility of appearance of immature leukocytes, atypical lymphocyte information indicating the possibility of appearance of atypical lymphocytes, and presence of nucleated red blood cells. The blood imaging apparatus according to claim 2, wherein at least one is selected from nuclear red blood cell information. 前記撮像条件は、前記血液像の撮像枚数を示す血球カウント数を含み、
第２撮像条件では、第１撮像条件よりも血球カウント数が多い請求項２又は３記載の血液撮像装置。 The imaging condition includes a blood cell count indicating the number of images of the blood image,
The blood imaging apparatus according to claim 2 or 3, wherein the second imaging condition has a larger blood cell count than the first imaging condition. 撮像された血液像に基づいて前記検体の血液の少なくとも白血球成分を分類するための分類手段を更に備えている請求項１〜３のいずれかに記載の血液撮像装置。   The blood imaging apparatus according to any one of claims 1 to 3, further comprising classification means for classifying at least a white blood cell component of blood of the specimen based on the imaged blood image. 前記撮像条件は、前記血液像の撮像枚数を示す血液カウント数を含み、
第１撮像条件では、所定の第１血液カウント数で撮像し、
第２撮像条件では、前記分類手段の分類結果に少なくとも１個の有核異常血球が含まれるまで撮像する請求項５記載の血液撮像装置。 The imaging condition includes a blood count indicating the number of images of the blood image,
In the first imaging condition, imaging is performed with a predetermined first blood count.
The blood imaging apparatus according to claim 5, wherein, under the second imaging condition, imaging is performed until at least one abnormal nucleated blood cell is included in the classification result of the classification unit. 前記第２撮像条件では、前記分類手段の分類結果に有核異常血球が含まれていなくても、所定の第２血液カウント数に達した場合には撮像を停止する請求項６記載の血液撮像装置。   7. The blood imaging according to claim 6, wherein, under the second imaging condition, imaging is stopped when a predetermined second blood count is reached even if nucleated abnormal blood cells are not included in the classification result of the classification means. apparatus. 前記第２血液カウント数は前記第１血液カウント数よりも多い請求項７記載の血液撮像装置。   The blood imaging apparatus according to claim 7, wherein the second blood count is greater than the first blood count. 前記有核異常血球は、幼若白血球、異型リンパ球及び有核赤血球から少なくとも１つ選択される請求項６〜８のいずれかに記載の血液撮像装置。 The nucleated abnormal blood cells, blood imaging device according to any one of immature leukocytes, claims 6-8 are at least one selected from atypical lymphocytes and nucleated red blood cells. 前記取得手段は、前記検体中における血小板凝集の出現の可能性を示す血小板凝集情報を含む血液分析情報を取得するものである請求項１記載の血液撮像装置。   The blood imaging apparatus according to claim 1, wherein the acquiring unit acquires blood analysis information including platelet aggregation information indicating a possibility of appearance of platelet aggregation in the specimen. 前記撮像条件は、血液標本を撮像する位置を含み、
前記第２撮像条件では、第１撮像条件の撮像位置よりも血小板凝集が存在する可能性の高い位置を撮像する請求項１０記載の血液撮像装置。 The imaging condition includes a position for imaging a blood sample,
The blood imaging apparatus according to claim 10, wherein the second imaging condition is used to image a position where platelet aggregation is more likely to exist than the imaging position of the first imaging condition. 前記第１撮像条件では、前記血液標本の中央部又は中央部付近を撮像し、
前記第２撮像条件では、前記血液標本の周縁部を撮像する請求項１１記載の血液撮像装置。 In the first imaging condition, the central portion of the blood sample or the vicinity of the central portion is imaged,
The blood imaging apparatus according to claim 11, wherein the second imaging condition images a peripheral portion of the blood sample. 前記取得手段は、前記検体中における異常細胞の出現の可能性を示す異常細胞情報を含む血液分析情報を出力する血液分析装置、及び／又は前記血液分析情報が蓄積された記憶部を有するコンピュータから前記血液分析情報を取得する請求項１〜１２のいずれかに記載の血液撮像装置。   The acquisition means includes: a blood analyzer that outputs blood analysis information including abnormal cell information indicating the possibility of abnormal cells appearing in the sample; and / or a computer having a storage unit in which the blood analysis information is stored. The blood imaging apparatus according to claim 1, wherein the blood analysis information is acquired. 前記血液標本は、前記検体中における異常細胞の出現の可能性を示す異常細胞情報を含む血液分析情報の標本記憶部を備えた標本担持体によって担持され、
前記取得手段は、前記標本記憶部から前記血液分析情報を取得する請求項１〜１２のいずれかに記載の血液撮像装置。 The blood specimen is carried by a specimen carrier having a specimen storage unit for blood analysis information including abnormal cell information indicating the possibility of appearance of abnormal cells in the specimen,
The blood imaging apparatus according to claim 1, wherein the acquisition unit acquires the blood analysis information from the specimen storage unit. 前記標本記憶部は、前記標本担持体に付された２次元コードである請求項１４記載の血液撮像装置。 The blood imaging apparatus according to claim 14, wherein the specimen storage unit is a two-dimensional code attached to the specimen carrier. 前記検体中の血液の血球成分を分析して前記検体中における異常細胞の出現の可能性を示す異常細胞情報を含む血液分析情報を出力する血液分析装置によって、前記検体中における異常細胞の出現の可能性を示す異常細胞情報を含む血液分析情報を生成するステップ、
前記血液分析情報が、検体中における異常細胞の出現の可能性を示している場合には、異常細胞の出現の可能性を示していない場合とは異なる撮像条件によって血液標本の撮像を行うステップ、
を含むことを特徴とする血液撮像方法。 By analyzing a blood cell component of blood in the sample and outputting blood analysis information including abnormal cell information indicating the possibility of appearance of abnormal cells in the sample, the appearance of abnormal cells in the sample Generating blood analysis information including abnormal cell information indicating the possibility,
When the blood analysis information indicates the possibility of the appearance of abnormal cells in the specimen, the step of imaging the blood sample under different imaging conditions from the case where the abnormal cells do not indicate the possibility of appearance,
A blood imaging method comprising: 検体の血液標本の血液像を撮像する撮像装置における撮像条件を設定するための処理装置であって、
前記検体中における異常細胞の出現の可能性を示す異常細胞情報を含む血液分析情報を取得する取得手段と、
前記血液分析情報が、検体中における異常細胞の出現の可能性を示している場合には、異常細胞の出現の可能性を示していない場合とは異なる撮像条件を設定する撮像条件設定手段と、
を備えている処理装置。 A processing device for setting imaging conditions in an imaging device that images a blood image of a blood sample of a specimen,
Acquisition means for acquiring blood analysis information including abnormal cell information indicating the possibility of appearance of abnormal cells in the specimen;
When the blood analysis information indicates the possibility of the appearance of abnormal cells in the sample, an imaging condition setting means for setting an imaging condition different from the case where the blood analysis information does not indicate the possibility of the appearance of abnormal cells;
A processing apparatus comprising: 検体の血液標本の血液像を撮像する撮像本体装置であって、
検体の血液標本の血液像を撮像する撮像部と、
請求項１７記載の処理装置によって設定された前記撮像条件を受け取って、当該撮像条件に従って前記撮像部を制御する制御部と、
を備えている撮像本体装置。 An imaging body device for imaging a blood image of a blood sample of a specimen,
An imaging unit for imaging a blood image of a blood sample of the specimen;
A control unit that receives the imaging condition set by the processing device according to claim 17 and controls the imaging unit according to the imaging condition;
An imaging main body apparatus comprising:
JP2005282291A 2005-09-28 2005-09-28 Blood imaging apparatus, blood imaging method, processing apparatus, and imaging main body apparatus Expired - Fee Related JP4690163B2 (en)

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JP2005282291A JP4690163B2 (en) 2005-09-28 2005-09-28 Blood imaging apparatus, blood imaging method, processing apparatus, and imaging main body apparatus
US11/528,757 US7796797B2 (en) 2005-09-28 2006-09-28 Apparatus for obtaining an image of a blood cell and method for obtaining an image of a blood cell

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JP4690165B2 (en) * 2005-09-29 2011-06-01 シスメックス株式会社 Blood imaging apparatus, blood imaging method, processing apparatus, and imaging main body apparatus
JP5423671B2 (en) * 2008-04-30 2014-02-19 コニカミノルタ株式会社 Blood aggregating capacity measuring device
JP5452058B2 (en) * 2009-03-31 2014-03-26 シスメックス株式会社 Blood analyzer
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CN107533047B (en) * 2015-03-31 2020-11-10 希森美康株式会社 Urine analysis system, imaging device, cell imaging device, urine analysis method, management device, and information processing method
JP7005176B2 (en) 2017-05-31 2022-01-21 シスメックス株式会社 Sample preparation device, sample preparation system, sample preparation method and particle analyzer
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