JP2007000259A - Specimen collecting needle, and method of filtering specimen by using specimen collecting implement, specimen collecting needle and specimen collecting container - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a specimen collecting needle to eliminate work relating with possibilities of transmission through blood, such as removing a stopper body, to reliably complete filtration in collecting a specimen by a filtering member of a specimen collecting container; and also to provide a method of filtering a specimen by using a specimen collecting implement, a specimen collecting needle, and a specimen collecting container. <P>SOLUTION: The specimen collecting needle 10 is equipped with the first hollow needle 12 with a needlepoint part 12a stuck through the stopper body 5, the second hollow needle 13 with a needlepoint part 13a to collect the specimen, and a hub 14 where the second hollow needle 13 is joined in an air-tight manner at an end part 13b. The first hollow needle 12 is detachably fit in the hub 14 at an end part 12b. The first hollow needle 12 communicates with the second hollow needle 13 through the hub 14. When A stands for the fitting force generated between the first hollow needle 12 and the stopper body 5 after sticking the first needle 12 through the stopper body 5, and B stands for the fitting force generated between the first hollow needle 12 and the hub 14, A is larger than B. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention relates to a sample collecting needle, a sample collecting tool, and a sample filtering method using the sample collecting needle and the sample collecting container used to introduce a liquid sample such as blood into the sample collecting container. .

  Conventionally, various non-centrifugal blood collection tubes configured to collect a blood sample with a vacuum blood collection needle using the reduced pressure in the container and filter the blood with a filter member housed therein have been proposed. Such blood collection tubes are disclosed in, for example, Patent Documents 1 to 5 below.

In a conventional non-centrifugal sample collection container, a stopper is inserted using a vacuum blood collection needle, and blood is collected using reduced pressure. Then, the collected blood is filtered by a filter member disposed in the sample collection container or combined with the sample collection container. In this case, after the blood collection is completed, the vacuum blood collection needle is removed. The collected blood passes through the filter member by using the reduced pressure remaining below the filter member, that is, in the portion where the filtered blood is stored. That is, blood is filtered by the pressure difference between the upper and lower portions of the filter member.
JP 2002-277357 A Japanese Patent No. 3015854 JP 11-290297 A JP-A-4-20856 JP 2001-321365 A

  However, when the upper and lower pressures of the filter member reach equilibrium, the driving force for filtration is lost and the filtration is stopped. For this reason, conventionally, it has been necessary to remove the plug body above the filter member, to create an atmospheric pressure above the filter member, to generate a pressure difference between the lower and upper sides of the filter member, and to proceed with filtration. However, since it is necessary to remove the stopper of the sample collection container from which the blood sample is collected, there is a possibility that the operator is contaminated by the adhesion of blood. In addition, when the stopper is removed from the sample collection container, the space above the filter member is largely released to the outside, and foreign matter may be mixed.

  On the other hand, in the sample collection container described in Patent Document 3 below, the inner tube in which the filter member is disposed below is hermetically inserted into the outer tube, and the inner tube is moved in a direction to be pulled out from the outer tube. The structure which can accelerate | stimulate filtration by making the pressure in the outer tube | pipe under a filter member low is disclosed. However, in this structure, the pressure difference due to the above operation is not sufficient for the driving force of the filtration, and there is a possibility that the filtration stops during the filtration.

  Further, in the sample collection container described in Patent Document 4 below, a filtered sample collection container that is sealed with a stopper in advance and whose inside is decompressed is connected to the sample collection container from which blood is collected and a filter member. In addition, it is configured so as to pass through the blood in the sample collection container and the filter member using the reduced pressure in the filtered sample collection container. Here, the degree of decompression in the sample collection container is relatively high, but there is a possibility that the filtration may stop midway.

  The object of the present invention is to take into account the current state of the prior art described above, when collecting a sample by the filter member of the sample collection container, it is only possible to quickly filter a sample such as blood using the reduced pressure in the container. Sample collection needle, sample collection tool, sample collection needle and sample collection, which can eliminate the work of blood infection such as removing the plug to ensure complete filtration. An object of the present invention is to provide a method for filtering a specimen using a container for use.

  A sample collection needle according to a first aspect of the present invention includes a sample collection unit that stores a collected liquid sample and has an opening, and a sample storage unit that stores a filtered sample. A sample provided with a container, a filter member provided in the sample collection unit for filtering the sample collected in the sample collection unit, and a plug body press-fitted into the opening so as to hermetically seal the opening A sample collection needle for use in a collection container, the first hollow needle having a needle tip portion for piercing the stopper, the second hollow needle having a needle tip portion for collecting the sample, and the needle tip portion And a hub to which the second hollow needle is air-tightly joined at the end opposite to the needle, and the first hollow needle can be removed from the hub at the end opposite to the needle tip portion. The first hollow needle and the second hollow needle communicate with each other via a hub, A> B, where A is the fitting force between the first hollow needle and the plug after the first hollow needle has pierced the plug, and B is the fitting force between the first hollow needle and the hub. It is characterized by being.

  A sample collection needle according to a second aspect of the present invention includes a sample collection unit that stores a collected liquid sample and has an opening, and a sample storage unit that stores a filtered sample. A sample provided with a container, a filter member provided in the sample collection unit for filtering the sample collected in the sample collection unit, and a plug body press-fitted into the opening so as to hermetically seal the opening A sample collection needle for use in a collection container, which is composed of a double needle structure of an inner needle and an outer needle, has a first hollow needle having a needle tip portion that pierces a stopper, and a sample. A second hollow needle having a needle tip portion to be collected and a hub to which the second hollow needle is airtightly joined at an end opposite to the needle tip portion, opposite to the needle tip portion At the end on the side, the inner needle is joined to the hub, and at the end opposite to the needle tip portion, The needle is detachably fitted to the hub, the inner needle and the second hollow needle communicate with each other via the hub, and the outer needle after the first hollow needle has pierced the plug body X> Y, where X is the fitting force with the stopper and Y is the fitting force between the outer needle and the hub.

  A sample collection tool according to the present invention includes a sample collection needle configured according to the present invention, and a holder having an open end into which a sample collection container can be inserted.

  The sample filtration method according to the present invention is a sample filtration method using a sample collection needle and a sample collection container configured according to the present invention, and the sample is introduced into the sample collection unit using the sample collection needle Then, the pressure in the sample collection unit is increased by communicating the sample collection unit with the outside.

  When the sample collection needle according to the first invention pierces the stopper of the sample collection container, the sample collection container is depressurized, and thus a sample such as blood is introduced into the sample collection unit. When a sample such as blood is introduced into the sample collection unit, filtration of the sample such as blood by the filter member proceeds due to a pressure difference between the sample collection unit and the sample storage unit in the container.

  The first hollow needle is detachably fitted to the hub, and the fitting force A between the first hollow needle and the plug body is greater than the fitting force B between the first hollow needle and the hub. When the specimen collection needle is removed from the collection container, the first hollow needle is removed from the hub, and the first hollow needle remains through the plug. Therefore, after the sample collection needle is removed from the plug, the sample collection unit communicates with the outside. Therefore, since the sample collection part is opened to the atmosphere and the pressure is increased, the sample filtration proceeds rapidly only by removing the sample collection needle. By using the specimen collection needle according to the present invention, it is possible to quickly and easily perform the collection from the collection of the specimen to the filtration without requiring another device.

  In the second invention, the first hollow needle is constituted by a double needle structure of an inner needle and an outer needle, and the outer needle is detachably fitted to the hub. Since the fitting force X is greater than the fitting force Y between the outer needle and the hub, when the sample collection needle is removed from the sample collection container, the outer needle is removed from the hub, and the outer needle pierces the plug. It remains as it is. Therefore, after the sample collection needle is removed from the plug, the sample collection unit communicates with the outside. Therefore, since the specimen collection part is opened to the atmosphere and the pressure is increased, the filtration of the specimen can be reliably completed without stopping the filtration halfway. Since filtration can be completed without removing the plug, the operator is less likely to be contaminated by blood adhesion, and foreign matter is less likely to enter the specimen.

  In the present invention, when a sample collection tool including a sample collection needle and a holder having an open end into which a sample collection container can be inserted is used, the holder can be easily grasped with fingers. Therefore, the sample collection needle can be easily removed from the sample collection container.

  In the sample filtering method using the sample collection needle and the sample collection container according to the present invention, the sample is collected by inserting a stopper with the sample collection needle and using the reduced pressure inside the sample collection container. It can be introduced into the sample collection part of the sample collection container. Then, after the sample is introduced, the sample collection unit and the outside are communicated with each other simply by removing the sample collection needle, whereby the pressure in the sample collection unit can be increased compared to the pressure in the sample storage unit. Therefore, using this pressure difference, the liquid sample can be filtered easily and quickly without the need for other members.

  Hereinafter, the present invention will be clarified by describing specific embodiments of the present invention with reference to the drawings.

  FIG. 1 is a schematic perspective view showing a specimen collection container 1 used for filtration of a specimen according to the first embodiment of the present invention.

  The sample collection container 1 has a container 2. The container 2 is a bottomed tubular container having an opening 2a at the upper end.

  The container 2 can be formed of an appropriate rigid material such as synthetic resin or glass. However, since it becomes easy to confirm the state after filtration from the outside, the container 2 is preferably made of a transparent material.

  A filter member 3 is disposed in the container 2. The filter member 3 can be made of an appropriate filter material that can separate blood into blood cell components and plasma or serum. In the present embodiment, the filter member 3 is accommodated in a substantially cylindrical filter holding container 4 having an opening 4a at the upper end.

  The filter member 3 is made of an appropriate filter material that removes solid matter in the specimen. Examples of such a filter material include fiber aggregates and fine particles.

  A plurality of through holes are formed at the bottom of the filter holding container 4. The through-hole has a diameter through which red blood cells do not pass, and thus is configured such that plasma or serum separated by the filter member flows downward and prevents the blood cells from moving downward.

  At the lower end of the filter holding container 4, a sample lower portion 4 b for filtering the filtered sample is formed. The specimen flow lower part 4 b is formed integrally with the filter holding container 4 and is formed so as to protrude downward from the bottom surface of the filter holding container 4. The specimen flow lower portion 4b has a hollow channel for flowing down the filtered specimen.

  The filter holding container 4 can be made of an appropriate material such as a synthetic resin or glass, but is not easily damaged and is made of a transparent synthetic resin in order to facilitate confirmation of filtration from the outside. It is desirable that

  In the sample collection container 1 of the present embodiment, the space inside the filter holding container 4 is the sample collection unit 2A, and the filter member 3 is disposed in the sample collection unit 2A. Samples collected before and during filtration are stored in the sample collection unit 2A. In the sample collection container 1, the space inside the container 2 below the filter member 3 is a sample storage portion 2B. The filtered sample is stored in the sample storage unit 2B.

  A stopper 5 is press-fitted into the opening 2 a of the container 2. The plug body 5 can be made of an elastomer or rubber such as styrene elastomer, ester elastomer, urethane elastomer, butyl rubber, halogenated butyl rubber, or natural rubber.

  The plug body 5 includes a large-diameter portion 5a having a relatively large diameter located outside the container 2, a medium-diameter portion 5b protruding downward from the bottom surface of the large-diameter portion 5a, and a bottom surface of the medium-diameter portion 5b. It has a small diameter part 5c protruding downward. The medium diameter part 5 b is press-fitted into the opening 2 a of the container 2, and the small diameter part 5 c is press-fitted into the opening 4 a of the filter holding container 4. The stopper 5 is press-fitted into the container 2 in a state where the inside of the container 2 is decompressed. In this embodiment, the inside of the container 2 is depressurized in advance to a pressure of 1 to 90 kPa.

  FIG. 2 is a partially cutaway front sectional view showing a main part of a sample collecting tool 11 including the sample collecting needle 10 according to the first embodiment.

  The sample collection needle 10 includes a first hollow needle 12 having a needle tip portion 12a at one end and a second hollow needle 13 having a needle tip portion 13a at one end. In FIG. 2, the second hollow needle 13 is shown to overlap vertically so that the first hollow needle 13 is on the upper side and the first hollow needle 12 is on the lower side. Further, the needle tip portion 13a of the second hollow needle 13 is shown to face upward so that the needle tip portion 12 of the first hollow needle 12 faces downward.

  The second hollow needle 13 is airtightly joined to the hub 14 in the vicinity of the end 13b of the second hollow needle 13 opposite to the needle tip portion 13a. The end 13 b of the second hollow needle 13 is inserted into the hub 14 so as not to reach the lower surface 14 a of the hub 14. Note that the end 13 b of the second hollow needle 13 may reach the lower surface 14 a of the hub 14.

  A fitting member 15 is attached in the vicinity of the end 12b of the first hollow needle 12 opposite to the needle tip portion 12a. On the upper surface 15 a of the fitting member 15, an inverted frustoconical recess 15 b is provided. The end 12 b of the first hollow needle 12 is located on the bottom surface of the recess 15 b of the fitting member 15.

  A hub 14 having a truncated cone shape whose lower end portion is slightly larger than the shape of the recess 15b is press-fitted into the recess 15b of the fitting member 15 from the lower surface 14a, and the first hollow needle 12 is detachably fitted to the hub 14. Are combined. Therefore, the end portion 12 b of the first hollow needle 12 faces the end portion 13 b of the second hollow needle 13 through the hub 14 at a predetermined interval. The first hollow needle 12 and the second hollow needle 13 are communicated with each other via the hub 14, and a flow path 16 for a specimen such as blood is formed. Note that the shape of the lower end portion of the hub 14 and the concave portion 15b of the fitting member 15 may be other than the truncated cone as long as it can be press-fitted and removed.

  In this embodiment, the hub 14 and the fitting member 15 are made of an elastic material such as rubber or elastomer, but may be made of a rigid material such as hard resin or metal.

  A cylindrical holder 17 that can be easily grasped with fingers is attached to the sample collecting needle 11 in the sample collecting tool 11. The inner diameter of the holder 17 is slightly larger than the outer diameter of the container 2 of the sample collection container 1. In order to allow the specimen collection container 1 to be inserted, the lower end 17a of the holder 17 is opened. In the center of the upper surface 17b of the holder 17, the specimen collecting needle 10 is fixed by the hub 14 portion. Accordingly, the first hollow needles 12 are arranged above and below the center of the space inside the holder 17.

  The holder 17 can be formed of an appropriate rigid material such as synthetic resin or glass. However, since it becomes easy to confirm from the outside that the first hollow needle 12 penetrates the plug body 5, the holder 17 is preferably made of a transparent material.

  Next, a sample collection method using the sample collection tool 11 including the sample collection needle 10 and the sample collection container 1 will be described with reference to a partially cutaway front sectional view of FIG.

  When collecting blood, the needle tip portion 13a of the second hollow needle 13 of the sample collecting tool 11 is inserted into the blood vessel of the blood sampled person, and the sample is collected from the lower end 17a of the holder 17 as shown in FIG. Insert the container 1 for use. When the specimen collection container 1 is inserted, the needle tip portion 12a of the first hollow needle 12 penetrates the stopper 5 and reaches the specimen collection section 2A. In the present embodiment, a liquid specimen can be introduced into the specimen collection part 2A using the reduced pressure in the container 2 for blood. That is, blood as a liquid sample passes through the flow path 16 communicated by the second hollow needle 13, the hub 14, and the first hollow needle 12 from the blood vessel of the blood sample, and passes through the first hollow needle 12. It is guided from the needle tip portion 12a to the specimen collecting part 2A in the container 2.

FIG. 4 is a partially cutaway front sectional view showing the state of the sample collection container 1 and the sample collection tool 11 when the sample collection tool 11 is removed from the sample collection container 1 after collecting a sample such as blood.
After the blood is introduced, the holder 17 is grasped with fingers and the sample collection tool 11 is removed from the sample collection container 1. At this time, the fitting force A between the first hollow needle 12 and the plug body 5 is made larger than the fitting force B between the first hollow needle and the hub. Accordingly, when the sample collection tool 11 is removed from the sample collection container 1, the first hollow needle 12 is removed from the hub 5 at the fitting portion of the fitting member 15, and the first hollow needle 12 is plugged into the plug body 5. Remains pierced. The sample collection unit 2A communicates with the outside by the first hollow needle 12 remaining in the stopper 5.

  Therefore, in the sample collection container 1, the pressure in the sample collection unit 2A increases, and blood is quickly filtered by the filter member 3 due to the pressure difference between the sample collection unit 2A and the sample storage unit 2B. Therefore, the pressure difference between the inside of the sample collection unit 2A above the filter member 3 and the inside of the sample storage unit 2B below the filter member 3 becomes high, and the filtration proceeds again. In this way, the filtration by the filter member 3 is reliably completed.

  After the filtration is completed, the grasping portion 5a of the plug body 5 is grasped by hand, and the plug body 5 and the filter holding container 4 are pulled out from the sample collection container 1. In this way, plasma or serum as a sample filtered from the sample storage unit 2B in the container 2 can be obtained. Therefore, the plasma or serum in the sample storage unit 2B can be immediately used for an automatic analyzer, or the plasma or serum in the sample storage unit 2B can be collected with a dropper or pipette.

  In the present embodiment, a recess 15b is provided in the fitting member 15 attached to the first hollow needle 12, and the hub 14 is press-fitted into the recess 15b, whereby the first hollow needle 12, the hub 14 and However, a recess may be provided on the lower surface 14a of the hub 14, and a fitting member may be press-fitted into the recess. Further, the end 12b of the first hollow needle 12 may be directly inserted into the hub 14 without being fitted with a fitting member, so that it can be detachably fitted. In other words, it is only necessary that the first hollow needle 12 remains so as to pass through the plug body 5 when the sample collection tool 11 is removed from the sample collection container 1.

  In the present embodiment, the end portion 12b of the first hollow needle 12 and the end portion 13b of the second hollow needle 13 do not necessarily need to be spaced apart from each other. One hollow needle 12 and the second hollow needle 13 may be communicated with each other.

  FIG. 5 is a partially cutaway front sectional view showing a main part of a collection needle 21 having a sample collection needle 20 according to the second embodiment of the present invention.

  The sample collection needle 20 is composed of a first hollow needle 22 and a second hollow needle 23 having a needle tip portion 23a at one end. The first hollow needle 22 has a double needle structure of an inner needle 22A having a needle tip portion 22Aa at one end and an outer needle 22B having a needle tip portion 22Ba at one end. Here, the diameter of the inner needle 22A and the diameter of the second hollow needle 23 are the same. The inner diameter of the outer needle 22B is slightly larger than the outer diameter of the inner needle 22A. In FIG. 5, the second hollow needle 23 is shown to overlap vertically so that the first hollow needle 22 is on the upper side and the first hollow needle 22 is on the lower side. Further, the needle tip portion 23a of the second hollow needle 23 is shown to face upward so that the needle tip portion 22Aa of the inner needle A and the needle tip portion 22Ba of the outer needle 22B are faced downward.

  The second hollow needle 23 is inserted from the upper surface 24a of the hub 24 at the end 23b opposite to the needle tip portion 23a of the second hollow needle 23 so that the hub 24 and the second hollow needle 23 are hermetically sealed. Are joined together. At the end 22Ab of the inner needle A opposite to the needle tip portion 22Aa, the inner needle 22A is inserted from the lower surface 24b of the hub 24, and the hub 24 and the inner needle 22A are joined. Through the hub 24, the end 22Ab of the inner needle 22A and the end 23b of the second hollow needle face each other at a predetermined interval. The inner needle 22A and the second hollow needle 23 communicate with each other via the hub 24, and a flow path 25 for a specimen such as blood is formed.

  The outer needle 22B is inserted from the lower surface 24a of the hub 24 at the end 22Bb of the outer needle 22B opposite to the needle tip portion 22Ba, and the hub 24 and the outer needle 22B are detachably fitted.

  Similar to the sample collection tool 11, a cylindrical holder 17 is attached to the sample collection tool 21 with a sample collection needle 20. A first hollow needle 22 configured by a double needle structure of an inner needle 22A and an outer needle 22B is disposed above and below the center of the space inside the holder 17.

  Next, a sample collection method using the sample collection tool 21 including the sample collection needle 20 and the sample collection container 1 will be described with reference to a partially cutaway front sectional view of FIG.

  When collecting blood, the needle tip portion 23a of the second hollow needle 23 of the sample collecting tool 21 is inserted into the blood vessel of the blood sampled person, and the sample is collected from the lower end 17a of the holder 17 as shown in FIG. Insert the container 1 for use. When the specimen collection container 1 is inserted, the needle tip portion 22a of the first hollow needle 22 penetrates the stopper 5 and reaches the specimen collection section 2A. In the present embodiment, a liquid specimen can be introduced into the specimen collection part 2A using the reduced pressure in the container 2 for blood. That is, blood as a liquid sample passes through the flow path 25 communicated by the second hollow needle 23, the hub 24, and the inner needle 22 from the blood vessel of the blood sample to be collected from the needle tip portion 22 </ b> Aa of the inner needle 22. 2 is guided to the specimen storage section 2A in the interior.

FIG. 7 is a partially cutaway front sectional view showing the state of the sample collection container 1 and the sample collection tool 21 when the sample collection tool 21 is removed from the sample collection container 1 after introducing a sample such as blood.
After blood is introduced, the holder 17 is grasped with fingers and the sample collection tool 21 is removed from the sample collection container 1. At this time, the fitting force X between the outer needle 22B and the plug 5 is made larger than the fitting force Y between the outer needle 22B and the hub 24. Therefore, when the sample collection tool 21 is removed from the sample collection container 1, the outer needle 22B is removed from the hub 5, and the outer needle 22B remains pierced through the plug body 5. Therefore, the sample collection part 2A and the outside are communicated with each other by the outer needle 22B remaining in the stopper 5.

  Therefore, also in the sample collection tool 21, the filtration can be reliably completed without removing the plug 5 from the tubular container 2. Since it is not necessary to remove the plug 5, there is no possibility that the operator adheres to blood and is contaminated. In addition, since there is no open state where the upper part of the sample collection unit 2A is opened to a large extent, there is no possibility of contamination.

  In this embodiment, the outer needle 22B and the hub 24 are fitted by press-fitting the outer needle 22B into the hub 24, but a fitting member is attached to the end 22Bb of the outer needle 22B to The needle 22B and the hub 24 may be fitted. Alternatively, the outer needle 22B and the hub 24 may be fitted by applying an adhesive or the like to the end 22Bb of the outer needle 22B. That is, it is only necessary that the outer needle 22 </ b> B remains with the stopper 5 being pierced when the sample collection tool 21 is removed from the sample collection container 1.

  Also in the present embodiment, the end portion 22Ab of the inner needle 22A and the end portion 23b of the second hollow needle 23 do not necessarily need to be spaced apart from each other, and are disposed so as to be in contact with the inner needle 22A. The 2nd hollow needle 23 may be connected.

  FIG. 8 is a front sectional view showing the specimen collection needle 10 according to the first embodiment described above. In the specimen collecting needle 10 shown in FIG. 8, the holder 17 shown in FIG. 2 is not provided. FIG. 9 is a front cross-sectional view showing the specimen collection needle 20 according to the second embodiment. The sample collection needle 20 shown in FIG. 9 is not provided with the holder 17 shown in FIG. Thus, in the present invention, the holder 17 is not necessarily essential.

  In the first and second embodiments, blood collection ends when the pressure in the sample collection container 1 and the pressure of the blood vessel become substantially equal. After blood collection is completed, the sample collection tool 111 is pulled out of the sample collection container 1 and the tourniquet is removed. However, if the tourniquet is first removed by mistake, the pressure in the blood vessel suddenly decreases, and thus blood in the sample collection container 1 may flow backward toward the blood vessel. Further, when the position where the sample collection container 1 is arranged is higher than the blood vessel, there is a possibility that backflow may occur due to the potential energy. On the other hand, the sample collection container 1 often contains an anticoagulant or a drug. Therefore, if a backflow occurs, the drug or anticoagulant may migrate to the blood vessel side and have an adverse effect. Therefore, in order to eliminate the risk of blood moving from the sample collection container to the blood vessel side by mistake, the sample collection needle may be provided with a backflow prevention structure in the hub, for example.

  In the first and second embodiments, the double-pipe structure sample collection container 1 is used. However, the sample collection container 1 is characterized by a structure for filtering a sample by a pressure difference as described above. The other structures can be changed as appropriate.

The typical perspective view for demonstrating the container for specimen collection used for filtration of the specimen concerning a 1st embodiment of the present invention. 1 is a partially cutaway front cross-sectional view showing a main part of a sample collecting tool including a sample collecting needle according to a first embodiment of the present invention. FIG. 2 is a partially cutaway front cross-sectional view for explaining the collection of a sample using a sample collection tool including a sample collection needle according to the first embodiment of the present invention and a sample collection container. FIG. 3 is a partially cutaway front cross-sectional view showing a state of a sample collection container and a sample collection needle after a sample collection needle is removed from the sample collection container after collecting a sample such as blood. The partial notch front sectional drawing which shows the principal part of the sample collection tool provided with the needle | hook for sample collection which concerns on the 2nd Embodiment of this invention. FIG. 6 is a partially cutaway front cross-sectional view for explaining the collection of a sample using a sample collection tool including a sample collection needle and a sample collection container according to a second embodiment of the present invention. FIG. 3 is a partially cutaway front cross-sectional view showing a state of the sample collection container after the sample collection tool is removed from the sample collection container after collecting a sample such as blood and the sample collection tool. 1 is a front sectional view showing a specimen collecting needle that is configured in the same manner as in the first embodiment of the present invention. FIG. 6 is a front cross-sectional view showing a specimen collecting needle configured in the same manner as in the second embodiment of the present invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 ... Sample collection container 2 ... Container 2a ... Opening 2A ... Specimen collection part 2B ... Specimen storage part 3 ... Filter member 4 ... Filter holding container 4a ... Opening 4b ... Sample flow-down part 5 ... Plug body 5a ... Grasping part 5b ... Large Diameter portion 5c ... Small diameter portion 10 ... Sample collection needle 11 ... Sample collection device 12 ... First hollow needle 12a ... Needle tip portion 12b ... End portion 13 ... Second hollow needle 13a ... Needle tip portion 13b ... End portion 14 ... Hub 14a ... Lower surface 15 ... Fitting member 15a ... Upper surface 15b ... Recess 16 ... Flow path 17 ... Holder 17a ... Lower end 17b ... Upper surface 20 ... Sample collection needle 21 ... Sample collection tool 22 ... First hollow needle 22A ... Inside Needle 22Aa ... Needle tip portion 22Ab ... End portion 22B ... Outer needle 22Ba ... Needle tip portion 22Bb ... End portion 23 ... Second hollow needle 23a ... Needle tip portion 23b ... End portion 24 ... Hub 24a ... Upper surface 24b ... Lower surface 25 ... Flow A ... fitting force between the first and the hollow needle and the plug fitting force B ... first fitting force between the hollow needle fitting of the hub resultant X ... outer needle and the plug Y ... outer needle and hub

Claims (4)

A sample collecting part for storing the collected liquid sample and having an opening;
A container body having a sample storage section for storing the filtered sample, and a container body whose inside is decompressed in advance;
A filter member provided in the sample collection unit for filtering the sample collected in the sample collection unit;
A sample collection needle for use in a sample collection container comprising a stopper pressed into the opening so as to hermetically seal the opening of the main body,
A first hollow needle having a needle tip portion for piercing the plug;
A second hollow needle having a needle tip portion for collecting a specimen;
A hub to which the second hollow needle is airtightly joined at an end opposite to the needle tip portion,
At the end opposite to the needle tip portion, the first hollow needle is detachably fitted to the hub,
The first hollow needle and the second hollow needle are communicated with each other via the hub,
The fitting force between the first hollow needle and the plug after the first hollow needle has pierced the plug is A, and the fitting force between the first hollow needle and the hub is B. A specimen collecting needle characterized in that sometimes A> B. A sample collecting part for storing the collected liquid sample and having an opening;
A container body having a sample storage section for storing the filtered sample, and a container body whose inside is decompressed in advance;
A filter member provided in the sample collection unit for filtering the sample collected in the sample collection unit;
A sample collection needle for use in a sample collection container comprising a stopper pressed into the opening so as to hermetically seal the opening of the main body,
A first hollow needle that has a double needle structure of an inner needle and an outer needle, and has a needle tip portion that pierces the stopper;
A second hollow needle having a needle tip portion for collecting a specimen;
A hub to which the second hollow needle is airtightly joined at an end opposite to the needle tip portion,
The inner needle is joined to the hub at the end opposite to the needle tip portion,
At the end opposite to the needle tip portion, the outer needle is detachably fitted to the hub,
The inner needle and the second hollow needle communicate with each other via the hub,
X> Y, where X is the fitting force between the outer needle and the plug after the first hollow needle has pierced the plug, and Y is the fitting force between the outer needle and the hub. A needle for collecting a specimen, characterized in that   A sample collection tool comprising the sample collection needle according to claim 1 and a holder having an open end into which the sample collection container can be inserted. A method for filtering a sample using the sample collection needle according to claim 1 or 2 and the sample collection container,
A method for filtering a sample, wherein after the sample is introduced into the sample collection unit using a sample collection needle, the sample collection unit is communicated with the outside to increase the pressure in the sample collection unit.

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