JP2006518752A5 - - Google Patents

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Publication number
JP2006518752A5
JP2006518752A5 JP2006503780A JP2006503780A JP2006518752A5 JP 2006518752 A5 JP2006518752 A5 JP 2006518752A5 JP 2006503780 A JP2006503780 A JP 2006503780A JP 2006503780 A JP2006503780 A JP 2006503780A JP 2006518752 A5 JP2006518752 A5 JP 2006518752A5
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JP
Japan
Prior art keywords
compound selected
pharmaceutically acceptable
acceptable salt
group
tables
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JP2006503780A
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English (en)
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JP4648303B2 (ja
JP2006518752A (ja
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Priority claimed from PCT/US2004/005199 external-priority patent/WO2004075840A2/en
Publication of JP2006518752A publication Critical patent/JP2006518752A/ja
Publication of JP2006518752A5 publication Critical patent/JP2006518752A5/ja
Application granted granted Critical
Publication of JP4648303B2 publication Critical patent/JP4648303B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Description

Figure 2006518752
Figure 2006518752
Figure 2006518752
Figure 2006518752
Figure 2006518752
Figure 2006518752
Figure 2006518752
Figure 2006518752
Figure 2006518752
Figure 2006518752
Figure 2006518752

Claims (1)

  1. 下記の群から選択される化合物または下記のいずれかの表から選択されるいずれかの化合物の製薬上許容される塩。
    Figure 2006518752
    Figure 2006518752
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    Figure 2006518752
    Figure 2006518752
    Figure 2006518752
    Figure 2006518752
    Figure 2006518752
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    Figure 2006518752
    Figure 2006518752
    Figure 2006518752
    Figure 2006518752
    Figure 2006518752
    Figure 2006518752
    Figure 2006518752
    Figure 2006518752
    Figure 2006518752
    Figure 2006518752
JP2006503780A 2003-02-25 2004-02-20 選択的非ステロイド系糖質コルチコイド受容体調節剤 Expired - Fee Related JP4648303B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45081103P 2003-02-25 2003-02-25
PCT/US2004/005199 WO2004075840A2 (en) 2003-02-25 2004-02-20 Selective non-steroidal glucocorticoid receptor modulators

Publications (3)

Publication Number Publication Date
JP2006518752A JP2006518752A (ja) 2006-08-17
JP2006518752A5 true JP2006518752A5 (ja) 2010-06-17
JP4648303B2 JP4648303B2 (ja) 2011-03-09

Family

ID=32927681

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006503780A Expired - Fee Related JP4648303B2 (ja) 2003-02-25 2004-02-20 選択的非ステロイド系糖質コルチコイド受容体調節剤

Country Status (8)

Country Link
US (1) US7411073B2 (ja)
EP (1) EP1599201B1 (ja)
JP (1) JP4648303B2 (ja)
AT (1) ATE464296T1 (ja)
AU (1) AU2004216182B2 (ja)
CA (1) CA2516684A1 (ja)
DE (1) DE602004026558D1 (ja)
WO (1) WO2004075840A2 (ja)

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JP4745609B2 (ja) * 2002-01-22 2011-08-10 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア グルココルチコイドレセプターのための非ステロイド性リガンド、その組成物および使用
DE60335869D1 (de) * 2002-04-11 2011-03-10 Merck Sharp & Dohme 1h-benzo(f)indazol-5-yl-derivate als selektive glucocorticoid-rezeptor-modulatoren
EP1617806B1 (en) * 2003-04-23 2009-11-04 Merck & Co., Inc. Selective spirocyclic glucocorticoid receptor modulators
US7888381B2 (en) 2005-06-14 2011-02-15 Bristol-Myers Squibb Company Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity, and use thereof
EP1916896A4 (en) * 2005-08-26 2010-08-11 Univ California NOT STEROID-antiandrogens
CA2667007A1 (en) * 2006-10-23 2008-05-02 Merck & Co., Inc. 2-[1-phenyl-5-hydroxy or methoxy-4alpha-methyl-hexahydrocyclopenta[f]indazol-5-yl]ethyl phenyl derivatives as glucocorticoid receptor ligands
JP2011500804A (ja) * 2007-10-23 2011-01-06 メルク・シャープ・エンド・ドーム・コーポレイション グルココルチコイド受容体リガンドの製造方法
AU2009217493B2 (en) * 2008-02-26 2013-06-13 Merck Sharp & Dohme Corp. Hexahydrocyclopentyl[f]indazole carboxamides and derivatives thereof as selective glucocorticoid receptor modulators
US20120172397A1 (en) * 2009-09-08 2012-07-05 Merck Sharp & Dohme Corp. HEXAHYDROCYCLOPENTA[f]INDAZOLE 5-YL ETHANOLS AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS
TW201118073A (en) * 2009-10-30 2011-06-01 Merck Sharp & Dohme Hexahydrocyclopentyl [F] indazole pyridyl ethanols and derivatives thereof as selective glucocorticoid receptor modulators
EP2493303A4 (en) * 2009-10-30 2013-06-26 Merck Sharp & Dohme 2- [1-PHENYL-5-HYDROXY-4A-SUBSTITUTED HEXAHYDROCYCLOPENTA [F] INDAZOL-5-YL] ETHYLPHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS
TW201422590A (zh) 2012-09-07 2014-06-16 Abbvie Inc 雜環核激素受體調節劑
EP2935284A4 (en) 2012-12-21 2016-04-27 Abbvie Inc HETEROCYCLIC MODULATORS OF HORMONE NUCLEAR RECEPTORS
WO2018191283A1 (en) * 2017-04-11 2018-10-18 Oric Pharmaceuticals, Inc. Glucocorticoid receptor modulators
US10981918B2 (en) * 2018-07-20 2021-04-20 Grünenthal GmbH Further substituted triazolo quinoxaline derivatives
US20220079924A1 (en) * 2018-10-10 2022-03-17 Oric Pharmaceuticals, Inc. Glucocorticoid receptor modulators
CA3123490A1 (en) 2019-01-22 2020-07-30 Akribes Biomedical Gmbh Selective glucocorticoid receptor modifiers for treating impaired skin wound healing

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932388A (en) * 1974-04-22 1976-01-13 Schering Corporation -Azido-4,6-pregnadieno(3,2-c)pyrazoles, processes for their preparation and intermediates useful therein
US4307102A (en) * 1981-02-19 1981-12-22 Sterling Drug Inc. Phenanthro[2,3-c]pyrazole
US4349558A (en) * 1981-02-19 1982-09-14 Sterling Drug Inc. Anti-inflammatory 8H-phenanthro-[2,3-c]pyrazole derivatives
DE3261485D1 (en) 1981-02-19 1985-01-24 Sterling Drug Inc Phenylpyrazole compounds useful as anti-inflammatory agents and preparation thereof
US4349559A (en) * 1981-02-19 1982-09-14 Sterling Drug Inc. Anti-inflammatory spiro-2H-indene-[2,3']-3H-pyrazolo[4",5":7',6']naphtho[2,1-b]pyran-1,3-dione derivatives
JP4745609B2 (ja) * 2002-01-22 2011-08-10 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア グルココルチコイドレセプターのための非ステロイド性リガンド、その組成物および使用
DE60335869D1 (de) 2002-04-11 2011-03-10 Merck Sharp & Dohme 1h-benzo(f)indazol-5-yl-derivate als selektive glucocorticoid-rezeptor-modulatoren
JP4520309B2 (ja) 2002-09-20 2010-08-04 メルク・シャープ・エンド・ドーム・コーポレイション 選択的糖質コルチコイド受容体調節剤としてのオクタヒドロ−２−Ｈ−ナフト［１，２−ｆ］インドール−４−カルボキサミド誘導体

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