JP2006116170A - Injection apparatus for medical use, plunger member for the same, and movement restricting mechanism for plunger member - Google Patents

Injection apparatus for medical use, plunger member for the same, and movement restricting mechanism for plunger member Download PDF

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JP2006116170A
JP2006116170A JP2004309231A JP2004309231A JP2006116170A JP 2006116170 A JP2006116170 A JP 2006116170A JP 2004309231 A JP2004309231 A JP 2004309231A JP 2004309231 A JP2004309231 A JP 2004309231A JP 2006116170 A JP2006116170 A JP 2006116170A
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outer cylinder
plunger member
plunger
injection
medical injector
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Tadashi Okiyama
忠 沖山
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JMS Co Ltd
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JMS Co Ltd
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Abstract

<P>PROBLEM TO BE SOLVED: To provide an injection apparatus which is operated with small force even in the case of high injection resistance, has a simple structure so as to be inexpensively produced, and has a simple cylindrical shape so as to be operated by one hand, to provide a syringe type injection apparatus for medical use having a simple structure to solve the above problems by simple component exchange in a normal disposable syringe, and to provide a component to be used for the component exchange. <P>SOLUTION: The injection apparatus for medical use comprises an outer cylinder 4 having a small diameter part (cylinder tip end part) 1 for pushing out an injection material at the distal end part and a large diameter part to which a plunger member is inserted from a rear end opening part; the plunger member 3 with a screw part formed on the front surface, which is inserted to the large diameter part of the outer cylinder from the rear end opening part of the outer cylinder; and a nut member 5 screwing the screw part of the plunger member outside the outer cylinder and having a screw part on the inner peripheral surface, which slides the plunger member in a front and rear direction in the large diameter part of the outer cylinder by rotating the plunger member. The nut member is attached/detached to/from the outer cylinder. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

本発明は特に大きな押出圧力を必要とする分野に使用する注射器型の医療用注入器、例えば硬膜外に麻酔剤を注入する際や高粘度の骨充填材を患部へ注入する場合の使用に適した注射器型の医療用注入器に関する。   The present invention is a syringe-type medical injector used in a field requiring a particularly high extrusion pressure, for example, when injecting an anesthetic agent into the epidural or injecting a highly viscous bone filler into an affected area. The present invention relates to a suitable syringe-type medical injector.

大きな押出圧力を必要とする分野に使用する注射器型の医療用注入器においては、例えば硬膜外麻酔において硬膜外に麻酔剤を注入する際には麻酔剤が充填されたシリンジにカテーテルを接続してシリンジのプランジャー部材を手で押して注入操作を行っているが、該注入器に接続したカテーテルが細いため注入抵抗が高くプランジャー部材を押す操作に多大の労力を要するという問題がある。また、骨欠損部の補修，補填などを目的としてペースト状等（流動状）の骨充填材を患部へプランジャー部材を手で押して注入操作を行っているが、このペースト状の骨充填剤をシリンジで骨肉に注入する場合にも注入抵抗が高いため、同様にプランジャー部材を押す操作に多大の労力を要するという問題があった。
前記大きな押出圧力を必要とする分野に使用する注射器型の医療用注入器において、注入する際の押出圧力をより小さくしプランジャー部材を押す操作の労力を軽減し、例えば片手操作により円滑確実に押出操作ができる注射器型の医療用注入器が望まれていた。前記問題点を解決するため、特開２００３―１０２７４０号公報に示される器具が考案されている。しかし、この器具は、構造が複雑で高価といった問題がある。 In a syringe-type medical injector used in a field that requires a large extrusion pressure, for example, when injecting an anesthetic agent outside the epidural in an epidural anesthesia, a catheter is connected to a syringe filled with the anesthetic agent. Then, the injection operation is performed by manually pushing the plunger member of the syringe. However, since the catheter connected to the injector is thin, the injection resistance is high, and there is a problem that the operation of pressing the plunger member requires a lot of labor. In addition, for the purpose of repairing and repairing bone defects, a paste-like (fluid) bone filler is injected into the affected area by manually pushing the plunger member into the affected area. In the case of injecting into the bone meat with a syringe, the injection resistance is high, so that there is a problem that a large amount of labor is required for the operation of pushing the plunger member.
In a syringe-type medical injector used in a field that requires a large extrusion pressure, the extrusion pressure during injection is reduced to reduce the effort of pushing the plunger member. A syringe-type medical injector capable of extrusion operation has been desired. In order to solve the above problems, an instrument disclosed in Japanese Patent Application Laid-Open No. 2003-102740 has been devised. However, this device has a problem that the structure is complicated and expensive.

特開２００３―１０２７４０号公報JP 2003-102740 A

本発明は、前記問題を解決し、注入抵抗が高い場合でも、軽い力で操作できるとともに、構造が単純で安価に製造でき、かつシンプルな円筒形状で片手操作が可能な注入器具の提供をその解決すべき技術課題とする。
また、本発明は通常のディスポシリンジを簡単な部品交換で前記課題を解決することができる構造の注射器型の医療用注入器、およびその部品交換に使用する部品の提供を目的とする。 The present invention solves the above problems and provides an injection device that can be operated with a light force even when the injection resistance is high, can be manufactured with a simple structure at low cost, and can be operated with a simple cylinder in one hand. Technical issues to be solved.
It is another object of the present invention to provide a syringe-type medical injector having a structure capable of solving the above-mentioned problems by simply exchanging a conventional disposable syringe, and components used for exchanging the components.

本発明は、先端部に注入材料を押出し可能な径小部（筒先部）および後端開口部からプランジャー部材が挿入可能な径大部を有する外筒と、前記外筒の後端開口部から前記外筒の径大部内に挿入可能で、その表面にネジ部が形成されたプランジャー部材とを少なくとも有して構成され、かつ注入時の注入材料の注入に必要とする圧力（注入圧力）に応じて外筒内のプランジャー部材の移動を、プランジャー部材の押引操作とプランジャー部材の回転操作のどちらかを選択して行うことを可能とする手段（プランジャー部材の移動規制機構）を備えていることを特徴とする医療用注入器、前記プランジャー部材および前記プランジャー部材の移動規制機構を提供することにより前記課題を解決することができた。   The present invention includes an outer cylinder having a small-diameter part (cylinder tip part) from which a pouring material can be extruded at a tip part and a large-diameter part into which a plunger member can be inserted from a rear end opening part, and a rear end opening part of the outer cylinder A pressure member (injection pressure) required to inject an injection material at the time of injection, and at least a plunger member having a threaded portion formed on the surface thereof. ) In accordance with (), a means that allows the plunger member to be moved by selecting either the plunger member push-pull operation or the plunger member rotation operation (plunger member movement restriction). By providing a medical injector, a plunger member, and a movement restricting mechanism for the plunger member, the above problem can be solved.

本発明の前記医療用注入器は、例えば１）人体に流動体を注入するための注入経路を設定する工程、２）前記注入経路に流動体の入った注入器を接続する工程、３）前記接続した注入器から人体に流動体を注入する工程、を含む流動体注入方法で使用できる。   The medical injector of the present invention includes, for example, 1) a step of setting an injection path for injecting a fluid into a human body, 2) a step of connecting an injector containing a fluid to the injection path, and 3) the above The method can be used in a fluid injection method including a step of injecting a fluid into a human body from a connected injector.

本発明の医療用注入器において、前記外筒は通常のディスポシリンジの外筒として入手可能なものの中から選択できる。また、外筒の先端部に形成された径小部（筒先部）は上述のように薬液や骨充填材等を押出し可能なものであればよく、またその使用目的、例えば上述のように骨充填材等を押出しや注射針を接続して薬液を注入する場合等に応じて適宜その形状や大きさを変更してもよい。   In the medical injector of the present invention, the outer cylinder can be selected from those available as an outer cylinder of a normal disposable syringe. Moreover, the small diameter part (cylinder tip part) formed in the front-end | tip part of an outer cylinder should just be a thing which can extrude a chemical | medical solution, a bone filler, etc. as mentioned above, and the use purpose, for example, bone as mentioned above The shape and size of the filler may be appropriately changed according to the case of extruding a filler or the like and injecting a chemical solution by connecting an injection needle.

前記プランジャー部材の移動規制機構としては、たとえば前記プランジャー部材のネジ部と外筒外で螺合するネジ部、および外筒の径大部の後端部に通常形成されているフランジ部に挿入可能な穴部あるいは溝部をその内周面に有し、かつ外筒と脱着可能に装着されるナット部材が挙げられる。   Examples of the movement restricting mechanism of the plunger member include a screw portion that is screwed with the screw portion of the plunger member outside the outer cylinder, and a flange portion that is normally formed at the rear end portion of the large diameter portion of the outer cylinder. A nut member that has an insertable hole or groove on its inner peripheral surface and is detachably attached to the outer cylinder.

該ナット部材はそれを外筒に装着した状態、例えば前記ナット部材のフランジ部に外筒のフランジ部を挿入し、かつ前記プランジャー部材のネジ部とナット部材のネジ部とを螺合した状態ではプランジャー部材の押引操作ではなくプランジャーの回転操作により大きな注入圧力を必要とする場合であっても、該プランジャーを押引操作に行う場合に比較して少ない力で外筒内を前後方向に移動させることができる。また、大きな注入圧力を必要としない場合には、プランジャー部材の移動規制機構である前記ナット部材を外筒から取外し、従来の押引操作を行う医療用注入器と同様の注入および吸引操作を行うことができる。   The nut member is mounted on the outer cylinder, for example, the flange part of the outer cylinder is inserted into the flange part of the nut member, and the screw part of the plunger member and the screw part of the nut member are screwed together Then, even when a large injection pressure is required not by the plunger pulling operation but by the plunger rotation operation, the inside of the outer cylinder can be moved with less force than when the plunger is used for the pushing operation. It can be moved back and forth. When a large injection pressure is not required, the nut member, which is a plunger member movement restricting mechanism, is removed from the outer cylinder, and injection and suction operations similar to those of a conventional medical injector that performs a push-pull operation are performed. It can be carried out.

プランジャー部材の移動規制機構である前記ナット部材は、上述のように外筒に装着された状態で外筒から簡単に取外しができ、かつ装着が可能であることが好ましいが、前記ナット部材を外筒のフランジ部に装着する場合、該フランジ部に簡単に装着でき、かつ装着した状態から容易に取外しが出来るように円形ではなくその一部が開放された円弧形状のもの（以下、Ｃ型ナット部材という）が好ましい。このＣ型ナット部材の形状、大きさ等は前記フランジ部の形状、大きさ等を考慮して適宜設定することができる。
ただし、本発明のプランジャー部材の移動規制機構は、外筒内のプランジャー部材の移動を、プランジャー部材の押引操作とプランジャー部材の回転操作のどちらかを選択して行うことを可能とするものであれば前記ナット部材には限定されない。 The nut member, which is a plunger member movement restricting mechanism, can be easily detached from the outer cylinder while being attached to the outer cylinder as described above, and is preferably attachable. When attached to the flange part of the outer cylinder, it is not circular but partly open in an arc shape so that it can be easily attached to the flange part and easily removed from the attached state (hereinafter referred to as C type) Nut member) is preferable. The shape, size, etc. of the C-type nut member can be appropriately set in consideration of the shape, size, etc. of the flange portion.
However, the plunger member movement restricting mechanism of the present invention can move the plunger member in the outer cylinder by selecting either the plunger member push-pull operation or the plunger member rotation operation. If it is, it will not be limited to the said nut member.

本発明の医療用注入器のプランジャー部材としては、例えばその表面に前記ナット部材の内周面に形成されたネジ部と螺合可能なネジ部が形成されたものが挙げられ、通常のディスポシリンジのプランジャー部材にネジを形成することにより容易に入手できる。また同様に本発明の医療用注入器の外筒も通常のディスポシリンジの外筒として入手可能なものの中から選択できる。   The plunger member of the medical injector of the present invention includes, for example, a member in which a screw portion that can be screwed with a screw portion formed on the inner peripheral surface of the nut member is formed on the surface thereof. It can be easily obtained by forming a screw on the plunger member of the syringe. Similarly, the outer cylinder of the medical injector of the present invention can be selected from those available as an outer cylinder of a normal disposable syringe.

以下、本発明の実施態様を図に基づいて説明する。
本実施態様の医療用注入器は図１に示すように先端部に硬膜外に麻酔剤を注入可能で注射針を接続可能な径小部（筒先部）１および後端開口部からプランジャー部材３が挿入可能な径大部９を有する透明なポリプロピレン製の外筒４と、前記外筒４の後端開口部から前記外筒４の径大部９内に挿入可能で、かつその表面にオスネジ部１０が形成され、先端部にガスケットが形成されたプランジャー部材３と、前記プランジャー部材３のオスネジ部１０と外筒外で螺合し、プランジャー部材３を回転することにより該プランジャー部材３を前記外筒４の径大部９内で前後方向にスライド可能なメスネジ部８をその内周面に有するＣナット部材５とを少なくとも有して構成される。なお、前記透明な外筒４としては、ポリプロピレン以外にポリカーボネート、環状ポリオレフィン、ポリエチレン、硝子などで構成されてもよい。前記ナット部材５は図１および図２の（ａ）に示すようにその穴部７にプランジャー部材３の後端部に形成されたフランジ部７を挿入するとともに、その内周面に形成されたメスネジ部８と前記プランジャー部材３の表面に形成されたオスネジ部１０と外筒外で螺合することにより、外筒４と脱着可能に装着され、また、図２の（ｂ）に示すように前記Ｃナット部材５は外筒４から取外しが可能なものである。 Hereinafter, embodiments of the present invention will be described with reference to the drawings.
As shown in FIG. 1, the medical injector according to the present embodiment includes a plunger from a small diameter portion (cylinder tip portion) 1 that can inject an anesthetic agent into the epidural epithelium and to which an injection needle can be connected and a rear end opening. A transparent polypropylene outer cylinder 4 having a large-diameter portion 9 into which the member 3 can be inserted, and a surface of the outer cylinder 4 that can be inserted into the large-diameter portion 9 of the outer cylinder 4 from the rear end opening of the outer cylinder 4. The plunger member 3 is formed with a male screw portion 10 and a gasket is formed at the tip thereof. The plunger member 3 is threadedly engaged with the male screw portion 10 of the plunger member 3 outside the outer cylinder, and the plunger member 3 is rotated to rotate the plunger member 3. The plunger member 3 is configured to have at least a C nut member 5 having a female screw portion 8 on its inner peripheral surface capable of sliding in the front-rear direction within the large-diameter portion 9 of the outer cylinder 4. The transparent outer cylinder 4 may be made of polycarbonate, cyclic polyolefin, polyethylene, glass or the like in addition to polypropylene. As shown in FIG. 1 and FIG. 2 (a), the nut member 5 has a flange portion 7 formed at the rear end portion of the plunger member 3 inserted into the hole portion 7 and is formed on the inner peripheral surface thereof. The external thread 4 is detachably mounted by screwing the female thread 8 and the male thread 10 formed on the surface of the plunger member 3 outside the external cylinder, and also shown in FIG. Thus, the C nut member 5 can be removed from the outer cylinder 4.

本発明の医療用注入器は、前記Ｃ形ナット部材を外筒に装着した状態でＣ形ナット部材のネジ部とプランジャー部材のネジ部が螺合し、プランジャー部材の回転操作によりプランジャー部材は外筒の径大部内を前後方向に自由にスライド可能であるので、注入抵抗が高い場合でもプランジャー部材の回転操作により軽い操作力で注入材料の注入操作を行うことができ、かつ外筒は単純な円筒形状であるので外筒は手で持ち易く、片手で外筒を保持した状態でも、その手でブランジャを回転することが可能である。   In the medical injector according to the present invention, the screw portion of the C-shaped nut member and the screw portion of the plunger member are screwed in a state where the C-shaped nut member is mounted on the outer cylinder, and the plunger is rotated by rotating the plunger member. Since the member can slide freely in the front-rear direction within the large diameter part of the outer cylinder, even when the injection resistance is high, the injection operation of the injection material can be performed with a light operation force by rotating the plunger member, and the outside Since the cylinder has a simple cylindrical shape, the outer cylinder is easy to hold by hand, and even when the outer cylinder is held with one hand, the hand can be rotated with that hand.

また、前記Ｃ形ナット部材は外筒への取付けおよび取外しが容易であるので、前記Ｃ形ナットを外筒から取外し外すという簡単な操作で必要な場合には汎用のディスボシリンジと同様の薬液充填、及び注入操作を行うために使用ができる。
さらに前記Ｃ形ナット部材は単純形状の１部品で構成されているので安価で、かつ再利用可能であり、また、上述のように前記Ｃ形ナット部材が取付けられる外筒部分は通常のディスポシリンジが有するフランジ部分をそのまま使用でき、さらにネジ部をその表面に有するガスケット付きプランジャー部材も通常のディスポシリンジのプランジャー部材表面に単にネジ部を形成したものであるので、本発明によると、注入抵抗が高い薬液の注入操作に使用可能な医療用注入器が、通常のディスポシリンジと同様の低コストで、あるいは簡単な部品交換で製造できる。
さらに、本発明の医療用注入器は単純な構造であるため、不具合が発生する危険性が低いといった、医療用具として重要な効果が得られる。 Further, since the C-shaped nut member can be easily attached to and detached from the outer cylinder, the chemical solution similar to that of a general-purpose disco syringe can be used by a simple operation of removing and removing the C-shaped nut from the outer cylinder. Can be used to perform filling and injection operations.
Furthermore, since the C-shaped nut member is composed of a single part having a simple shape, the C-shaped nut member is inexpensive and reusable. As described above, the outer cylinder portion to which the C-shaped nut member is attached is a normal disposable syringe. The flange part of the gasket can be used as it is, and the plunger member with a gasket having a screw part on its surface is also a simple screw part formed on the plunger member surface of a normal disposable syringe. A medical injector that can be used for the injection operation of a highly resistant chemical solution can be manufactured at the same low cost as a normal disposable syringe or by simple component replacement.
Furthermore, since the medical injector of the present invention has a simple structure, it is possible to obtain an important effect as a medical device such that the risk of occurrence of a malfunction is low.

本発明の医療用注入器の側面図である。It is a side view of the medical injector of the present invention. 図１のＩ−Ｉ′の断面図である（ネジ部は不図示）。It is sectional drawing of II 'of FIG. 1 (a screw part is not shown).

符号の説明Explanation of symbols

１ 注射針が接続可能な外筒の径小部（筒先部）
２ ガスケット
３ プランジャー部材
４ 外筒
５ Ｃ型ナット
６ 後端開口部からプランジャー部材が挿入可能な透明な外筒の径大部
７ 外筒のフランジ部が挿入可能なＣ型ナットの穴部
８ Ｃ型ナットの内周面に形成された雌ネジ
９ 後端開口部からプランジャー部材が挿入可能な外筒の径大部
１０ プランジャー部材３の外周面に形成された雄ネジ
1 Small diameter part (cylinder tip) of the outer cylinder to which the injection needle can be connected
2 Gasket 3 Plunger member 4 Outer cylinder 5 C-type nut 6 Large diameter portion of transparent outer cylinder into which plunger member can be inserted from rear end opening 7 Hole of C-type nut into which flange of outer cylinder can be inserted 8 Female screw 9 formed on the inner peripheral surface of the C-type nut 9 Large diameter portion 10 of the outer cylinder into which the plunger member can be inserted from the rear end opening 10 Male screw formed on the outer peripheral surface of the plunger member 3

Claims (12)

先端部に注入材料を押出し可能な径小部（筒先部）および後端開口部からプランジャー部材が挿入可能な径大部を有する外筒と、前記外筒の後端開口部から前記外筒の径大部内に挿入可能で、その表面にネジ部が形成されたプランジャー部材とを少なくとも有して構成され、かつ注入時の注入材料の注入に必要とする圧力（注入圧力）に応じて外筒内のプランジャー部材の移動を、プランジャー部材の押引操作とプランジャー部材の回転操作のどちらかを選択して行うことを可能とする手段（プランジャー部材の移動規制機構）を備えていることを特徴とする医療用注入器。 An outer cylinder having a small-diameter part (cylinder tip part) from which the injection material can be extruded at the front end part and a large-diameter part into which a plunger member can be inserted from the rear end opening part, and the outer cylinder from the rear end opening part of the outer cylinder The plunger member can be inserted into the large-diameter portion, and has at least a plunger member having a threaded portion formed on the surface thereof, and according to the pressure (injection pressure) required for injection of the injection material at the time of injection Provided with means (plunger member movement restriction mechanism) that enables the plunger member to move within the outer cylinder by selecting either the plunger member push-pull operation or the plunger member rotation operation. A medical injector characterized by that. プランジャー部材の移動規制機構が前記プランジャー部材のネジ部と外筒外で螺合するネジ部をその内周面に有するナット部材であることを特徴とする請求項１に記載の医療用注入器。 2. The medical injection according to claim 1, wherein the movement restricting mechanism of the plunger member is a nut member having a screw portion screwed on the outer periphery of the screw portion of the plunger member on an inner peripheral surface thereof. vessel. ナット部材が外筒のフランジ部に脱着可能なものであることを特徴とする請求項２に記載の医療用注入器。 The medical injector according to claim 2, wherein the nut member is detachable from a flange portion of the outer cylinder. プランジャー部材の外周表面に雄ネジ、またナット部材の内周面に雌ネジが形成されたものであることを特徴とする請求項２または３に記載の医療用注入器。 The medical injector according to claim 2 or 3, wherein a male screw is formed on the outer peripheral surface of the plunger member and a female screw is formed on the inner peripheral surface of the nut member. ナット部材が該ナット部材を外筒に脱着可能に装着するための装着部を有することを特徴とする請求項２〜４のいずれかに記載の医療用注入器。 The medical injector according to any one of claims 2 to 4, wherein the nut member has an attachment portion for detachably attaching the nut member to the outer cylinder. 装着部が外筒の後端部に形成されているフランジ部に挿入可能な穴部あるいは溝部であることを特徴とする請求項５に記載の医療用注入器。 6. The medical injector according to claim 5, wherein the mounting portion is a hole portion or a groove portion that can be inserted into a flange portion formed at a rear end portion of the outer cylinder. ナット部材がその一部が開放された形状のもの（以下、Ｃ型ナットという）であることを特徴とする請求項２〜６のいずれかに記載の記載の医療用注入器。 The medical injector according to any one of claims 2 to 6, wherein the nut member has a shape in which a part thereof is opened (hereinafter referred to as a C-type nut). 医療用注入器の外筒内に挿入されたネジ部を表面部に有するプランジャー部材の前記ネジ部と螺合し、プランジャー部材を回転することにより該プランジャー部材が前記外筒内を前後方向にスライド可能とするネジ部をその内周面に有するとともに、前記外筒に脱着自在に装着可能なナット部材。 A screw portion inserted into the outer cylinder of the medical injector is screwed with the screw portion of the plunger member having a surface portion thereof, and the plunger member is rotated back and forth in the outer cylinder by rotating the plunger member. A nut member that has a screw portion that is slidable in a direction on its inner peripheral surface and that can be detachably attached to the outer cylinder. ナット部材がＣ型であることを特徴とする請求項８に記載のナット部材。 The nut member according to claim 8, wherein the nut member is C-shaped. ネジ部を表面部に有し、医療用注入器の外筒内に挿入されるプランジャー部材であって、前記ネジ部が外筒に脱着自在に装着されるナット部材の内周面に形成されたネジ部と螺合し、かつ該プランジャー部材を回転することにより前記外筒内を前後方向にスライド可能であることを特徴とするプランジャー部材。 A plunger member having a screw portion on a surface portion and inserted into an outer cylinder of a medical injector, wherein the screw portion is formed on an inner peripheral surface of a nut member that is detachably attached to the outer cylinder. A plunger member, wherein the plunger member is slidable in the front-rear direction in the outer cylinder by being screwed with the threaded portion and rotating the plunger member. 請求項８または９に記載のナット部材と請求項１０に記載のプランジャー部材よりなる医療用注入器の構成部材。 A component of a medical injector comprising the nut member according to claim 8 or 9 and the plunger member according to claim 10. １） 人体に流動体を注入するための注入経路を設定する工程、２） 前記注入経路に流動体の入った注入器を接続する工程、３） 前記接続した注入器から人体に流動体を注入する工程、を含む流動体注入方法で使用する前記注入器であって、流動体流出口、プランジャーを挿通する開口部を有する外筒と、前記開口部から挿通されたプランジャーとからなり、プランジャーは回転操作によって進退可能に構成されている医療用注入器。 1) a step of setting an injection path for injecting a fluid into the human body, 2) a step of connecting an injector containing the fluid to the injection path, and 3) injecting a fluid from the connected injector into the human body. A fluid injecting method comprising a fluid outlet, a fluid outlet, an outer cylinder having an opening through which the plunger is inserted, and a plunger inserted through the opening, The plunger is a medical injector that can be moved forward and backward by rotating operation.
JP2004309231A 2004-10-25 2004-10-25 Injection apparatus for medical use, plunger member for the same, and movement restricting mechanism for plunger member Pending JP2006116170A (en)

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