JP2006111604A5 - - Google Patents

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JP2006111604A5
JP2006111604A5 JP2004308046A JP2004308046A JP2006111604A5 JP 2006111604 A5 JP2006111604 A5 JP 2006111604A5 JP 2004308046 A JP2004308046 A JP 2004308046A JP 2004308046 A JP2004308046 A JP 2004308046A JP 2006111604 A5 JP2006111604 A5 JP 2006111604A5
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Japan
Prior art keywords
activated carbon
spherical activated
adsorbent
oral administration
modified spherical
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JP2004308046A
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Japanese (ja)
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JP4382629B2 (en
JP2006111604A (en
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Priority claimed from JP2004308046A external-priority patent/JP4382629B2/en
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Publication of JP2006111604A5 publication Critical patent/JP2006111604A5/ja
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Description

本発明の好ましい態様においては、前記表面改質球状活性炭の原料が熱溶融性樹脂である。
本発明の別の好ましい態様においては、前記表面改質球状活性炭の原料が熱不溶融性樹脂である。
本発明の更に別の好ましい態様においては、前記表面改質球状活性炭の原料がピッチである。
本発明の更に別の好ましい態様においては、前記表面改質球状活性炭が、球状活性炭を３００℃〜８００℃で酸化処理し、更に８００℃〜１２００℃で還元処理を行うことにより調製した表面改質球状活性炭である。
更に、本発明は、前記の経口投与用吸着剤のいずれかを有効成分とする、腎疾患治療又は予防剤、あるいは肝疾患治療又は予防剤にも関する。 In a preferred embodiment of the present invention, the raw material for the surface-modified spherical activated carbon is a hot-melt resin.
In another preferred embodiment of the present invention, the raw material of the surface-modified spherical activated carbon is a heat infusible resin.
In still another preferred embodiment of the present invention, the raw material of the surface-modified spherical activated carbon is pitch.
In still another preferred embodiment of the present invention, the surface-modified spherical activated carbon is a surface modified powder prepared by oxidizing spherical activated carbon at 300 ° C. to 800 ° C. and further reducing at 800 ° C. to 1200 ° C. Spherical activated carbon.
Furthermore, the present invention also relates to a renal disease treatment or prevention agent, or a liver disease treatment or prevention agent comprising any one of the above-mentioned adsorbents for oral administration as an active ingredient.

Claims (7)

平均粒子径が０．０１〜１ｍｍであり、ＢＥＴ法により求められる比表面積が７００ｍ２／ｇ以上であり、細孔直径７．５〜１５０００ｎｍの細孔容積が０．２５ｍＬ／ｇ〜１．０ｍＬ／ｇであり、全酸性基が０．３０ｍｅｑ／ｇ〜１．２０ｍｅｑ／ｇであり、そして全塩基性基が０．２０ｍｅｑ／ｇ〜０．７ｍｅｑ／ｇである表面改質球状活性炭からなることを特徴とする、経口投与用吸着剤。 The average particle diameter is 0.01 to 1 mm, the specific surface area determined by the BET method is 700 m 2 / g or more, and the pore volume with a pore diameter of 7.5 to 15000 nm is 0.25 mL / g to 1.0 mL. A surface-modified spherical activated carbon having a total acidic group of 0.30 meq / g to 1.20 meq / g and a total basic group of 0.20 meq / g to 0.7 meq / g. An adsorbent for oral administration, characterized by 前記表面改質球状活性炭の原料が熱溶融性樹脂である、請求項１記載の経口投与用吸着剤。  The adsorbent for oral administration according to claim 1, wherein the raw material of the surface-modified spherical activated carbon is a heat-meltable resin. 前記表面改質球状活性炭の原料が熱不溶融性樹脂である、請求項１記載の経口投与用吸着剤。  The adsorbent for oral administration according to claim 1, wherein the raw material of the surface-modified spherical activated carbon is a heat infusible resin. 前記表面改質球状活性炭の原料がピッチである、請求項１記載の経口投与用吸着剤。  The adsorbent for oral administration according to claim 1, wherein the raw material of the surface-modified spherical activated carbon is pitch. 前記表面改質球状活性炭が、球状活性炭を３００℃〜８００℃で酸化処理し、更に８００℃〜１２００℃で還元処理を行うことにより調製した表面改質球状活性炭である、請求項１記載の経口投与用吸着剤。  The oral surface according to claim 1, wherein the surface-modified spherical activated carbon is a surface-modified spherical activated carbon prepared by oxidizing spherical activated carbon at 300 ° C to 800 ° C and further performing reduction treatment at 800 ° C to 1200 ° C. Adsorbent for administration. 請求項１〜５のいずれか一項に記載の経口投与用吸着剤を有効成分とする、腎疾患治療又は予防剤。 A therapeutic or prophylactic agent for renal diseases, comprising the adsorbent for oral administration according to any one of claims 1 to 5 as an active ingredient. 請求項１〜５のいずれか一項に記載の経口投与用吸着剤を有効成分とする、肝疾患治療又は予防剤。 The liver disease treatment or prevention agent which uses the adsorption agent for oral administration as described in any one of Claims 1-5 as an active ingredient.
JP2004308046A 2003-10-22 2004-10-22 Oral adsorbent, renal disease treatment or prevention agent, and liver disease treatment or prevention agent Expired - Fee Related JP4382629B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2004308046A JP4382629B2 (en) 2003-10-22 2004-10-22 Oral adsorbent, renal disease treatment or prevention agent, and liver disease treatment or prevention agent

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2003362498 2003-10-22
JP2004266198 2004-09-14
JP2004308046A JP4382629B2 (en) 2003-10-22 2004-10-22 Oral adsorbent, renal disease treatment or prevention agent, and liver disease treatment or prevention agent

Publications (3)

Publication Number Publication Date
JP2006111604A JP2006111604A (en) 2006-04-27
JP2006111604A5 true JP2006111604A5 (en) 2007-11-29
JP4382629B2 JP4382629B2 (en) 2009-12-16

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JP2004308046A Expired - Fee Related JP4382629B2 (en) 2003-10-22 2004-10-22 Oral adsorbent, renal disease treatment or prevention agent, and liver disease treatment or prevention agent

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Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2006123618A1 (en) * 2005-05-16 2008-12-25 株式会社クレハ Oxidative stress inhibitor
JP5376592B2 (en) * 2009-10-15 2013-12-25 産協企業有限股▲ふん▼公司 Spherical activated carbon and manufacturing method thereof
JP5765649B2 (en) * 2010-03-10 2015-08-19 株式会社ダステック Adsorbed charcoal and adsorbent
JP2012051870A (en) 2010-08-02 2012-03-15 Asahi Organic Chemicals Industry Co Ltd Adsorbent for oral administration, method for manufacturing the same, and drug using the same
JP5985027B2 (en) * 2010-10-12 2016-09-06 フタムラ化学株式会社 Method for producing pharmaceutical adsorbent for oral administration
JP5984352B2 (en) * 2010-10-12 2016-09-06 フタムラ化学株式会社 Method for producing pharmaceutical adsorbent for oral administration
GB201204696D0 (en) * 2012-03-16 2012-05-02 Ucl Business Plc Therapy
JP5781992B2 (en) * 2012-08-09 2015-09-24 関西熱化学株式会社 Parenteral adsorbent provided with basic functional group and method for producing the same
JP6749117B2 (en) * 2016-03-28 2020-09-02 株式会社アドール Method for producing activated carbon containing at least one of a simple metal and a metal compound

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