JP2006084366A - Automatic analyzer - Google Patents

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JP2006084366A
JP2006084366A JP2004270659A JP2004270659A JP2006084366A JP 2006084366 A JP2006084366 A JP 2006084366A JP 2004270659 A JP2004270659 A JP 2004270659A JP 2004270659 A JP2004270659 A JP 2004270659A JP 2006084366 A JP2006084366 A JP 2006084366A
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reagent
cold air
cooler
automatic analyzer
air
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JP4248470B2 (en
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Koichi Asada
耕一 浅田
Isao Yamazaki
功夫 山崎
Tomoyuki Onomura
知幸 小野村
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Hitachi Science Systems Ltd
Hitachi High Tech Corp
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Hitachi High Technologies Corp
Hitachi Science Systems Ltd
Hitachi High Tech Corp
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Abstract

<P>PROBLEM TO BE SOLVED: To provide an automatic analyze provided with a reagent thermal insulation box capable of preventing water condensed in the reagent thermal insulation box from dripping into a reagent bottle. <P>SOLUTION: In the reagent thermal insulation box of the automatic analyzer, a structure is provided wherein cold air is blown out of every reagent removal opening. The reagent removal opening has a wall partitioning cold air and outside air. A door for reagent removal is installed with a hygroscopic material in a periphery, and it has a drain hole for draining excessive condensation water. By this, dew condensation in the reagent thermal insulation box, and inflow of condensation water can be prevented. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

本発明は、血液,尿等の生体サンプル中に含まれる各種の成分の定性・定量分析する自動分析装置に係り、特に分析のための試薬を入れた試薬ボトルを収納する試薬保冷庫を備えた自動分析装置に関する。   The present invention relates to an automatic analyzer for qualitative / quantitative analysis of various components contained in a biological sample such as blood and urine, and more particularly to a reagent cold storage for storing a reagent bottle containing a reagent for analysis. The present invention relates to an automatic analyzer.

従来の試薬保冷庫は、試薬ボトルを出し入れするための開放部分をもち、その開放部分には冷気が庫外に逃げ出すのを防止するため、カバーが設けられている。そのカバーは一般に保冷庫の上壁部として用いられ、カバーには試薬分注プローブが試薬ボトルから必要量の試薬を分取するための通過部として必要な比較的小さな切り欠きや孔(試薬吸入口)が設けられている。   The conventional reagent cold storage has an open part for taking in and out the reagent bottle, and a cover is provided in the open part to prevent the cold air from escaping outside the container. The cover is generally used as the upper wall of the cold storage, and the cover has relatively small cutouts and holes (reagent inhalation) necessary as a passage for the reagent dispensing probe to dispense a required amount of reagent from the reagent bottle. Mouth).

しかし、その孔から高温多湿な外気が試薬保冷庫内に進入し、カバー裏に接触して露点以下になった場合、カバー裏に結露して生じた水滴が試薬ボトル内に滴下する可能性があった。このような滴下により、試薬の薄まりによる分析精度の低下、あるいは試薬の劣化の恐れがあった。特許文献1では、カバー裏面を傾斜させることにより結露を一箇所に集めることにより、結露が試薬容器に混入するのを防ぐ技術が開示されている。   However, if hot and humid outside air enters the reagent cooler through the hole and contacts the back of the cover and falls below the dew point, water droplets generated by condensation on the back of the cover may drop into the reagent bottle. there were. Due to such dripping, there is a risk that the analytical accuracy may be reduced due to the thinning of the reagent, or the reagent may be deteriorated. Patent Document 1 discloses a technique for preventing condensation from being mixed into a reagent container by collecting condensation in one place by tilting the back surface of the cover.

特開平08−262030号公報JP 08-262030 A

上記従来技術では、カバーの構造が複雑,高価であり、かつ、結果的に高温多湿の外気が庫内に入ってくることを想定しているため、試薬保冷庫内の温度分布に差異が生じてしまう。従って、試薬は結露の影響は受けにくいが、温度による影響を受けやすいため安定性に欠けるという問題がある。   In the above prior art, the cover structure is complicated and expensive, and as a result, it is assumed that high temperature and high humidity outside air enters the cabinet, resulting in a difference in the temperature distribution in the reagent refrigerator. End up. Therefore, the reagent is not easily affected by dew condensation, but has a problem of lacking stability because it is easily affected by temperature.

本発明の目的は、試薬保冷庫の上壁内面に結露した水滴が試薬ボトル内に滴下するのを防止できる試薬保冷庫を備えた自動分析装置を提供することにある。   An object of the present invention is to provide an automatic analyzer having a reagent cooler that can prevent water droplets condensed on the inner surface of the upper wall of the reagent cooler from dropping into the reagent bottle.

上記目的を達成するための本発明の構成は以下の通りである。   The configuration of the present invention for achieving the above object is as follows.

空冷式の保冷庫を用い、試薬ボトル口に対応している試薬取り出し口から冷気が全て吹き出し状態になる保冷庫構造を備えた試薬保冷庫を具備した自動分析装置。   An autoanalyzer equipped with a reagent cooler having an air cooler structure in which all of the cold air is blown out from a reagent outlet corresponding to the reagent bottle mouth using an air-cooled cooler.

具体的には、複数の試薬容器を載置する試薬収容部と、該試薬収容部に隣接し、冷却器からの冷気を導入する冷気導入室と、該冷却器に冷気を戻す冷気排出室を備えた冷気循環部と、該冷気導入室から前記試薬収容部に冷気を導入する冷気導入口と、前記試薬収容部から前記冷気排出室に冷気を排出する冷気排出口と、前記冷気排出室の前記冷却器の近傍に、外気を該冷気排出室に導入する外気導入口と、を備えた試薬保冷庫を具備する自動分析装置である。   Specifically, there are provided a reagent storage unit for placing a plurality of reagent containers, a cool air introduction chamber for introducing cool air from a cooler adjacent to the reagent storage unit, and a cool air discharge chamber for returning cool air to the cooler. A cold air circulation unit, a cold air introduction port for introducing cold air from the cold air introduction chamber to the reagent storage unit, a cold air discharge port for discharging cold air from the reagent storage unit to the cold air discharge chamber, and a cooling air discharge chamber In the vicinity of the cooler, there is provided an automatic analyzer comprising a reagent cooler equipped with an outside air introduction port for introducing outside air into the cold air discharge chamber.

取り出し口の周囲を壁で覆い外気と接触して発生する結露水が庫内に流れ込まない構造とし、試薬取出し用ドアに吸湿材の取付け部を有し、余剰結露水を廃液するドレン孔を有する構造を備えても良い。   Cover the area around the outlet with a wall and contact with the outside air so that the condensed water does not flow into the cabinet, and the reagent removal door has a moisture absorbent mounting part and a drain hole for draining excess condensed water A structure may be provided.

本発明によれば、試薬保冷庫内への結露水の浸入を防止することができる。それゆえ、安定した信頼性の高いデータが得られる。   According to the present invention, it is possible to prevent the entry of condensed water into the reagent cold storage. Therefore, stable and highly reliable data can be obtained.

本発明により、試薬保冷庫内に高温多湿の外気が侵入しないため、試薬ボトルへの結露の滴下を防げる。試薬取り出し口の外で発生する結露水は壁の存在により、試薬庫内に流れ込むことは無い。試薬ボトル交換時に開閉する試薬取出し用ドアに吸湿材を収容しておけば、これが結露水を吸収するため、試薬取出し用ドアを開閉する際に試薬ボトル内に滴下することはない。また、吸収しきれない余剰の結露水が発生した場合は、近くにあけたドレン孔から廃液される。従って、試薬の薄まりや劣化による影響を受けることなく安定したデータが得られる。   According to the present invention, since high temperature and high humidity outside air does not enter the reagent cool box, it is possible to prevent condensation from dripping onto the reagent bottle. Condensed water generated outside the reagent outlet does not flow into the reagent storage due to the presence of the wall. If a moisture absorbing material is accommodated in the reagent removal door that opens and closes when the reagent bottle is replaced, it absorbs condensed water, so that it does not drop into the reagent bottle when the reagent removal door is opened and closed. Moreover, when excessive dew condensation water which cannot be absorbed is generated, it is drained from a drain hole opened nearby. Therefore, stable data can be obtained without being affected by the thinning or deterioration of the reagent.

以下、本発明の実施例を図により説明する。   Embodiments of the present invention will be described below with reference to the drawings.

通常、試薬保冷庫内は5〜15度に保冷されている。そこへ高温多湿の外気が試薬保冷庫カバーの試薬取り出し口1から侵入して冷えたカバー裏に接触すると、その外気の温度が下がり露点以下になると結露して水滴が生じる。図1のような、空冷式保冷庫の密閉された冷気循環では、試薬保冷庫カバー上に設けられた数個の試薬取り出し口1においては、保冷庫内の冷気循環が内周から外周に向けて流れているため、気圧差が生じ内周側と外周側で冷気吹出し側と外気導入側に分かれてしまう。図4に本発明の上面図を示す。上面図から見ると保冷庫は円形をしている。保冷庫は試薬容器を収容する試薬収容部とその下に設けられた内周と外周を隔絶する仕切り壁8を備えた冷気循環部を備える。冷気循環部では冷却器のIN側から導入した冷気が中央のリング外周部の角穴9と中段の仕切り板
10の丸穴11を通過し、仕切り板10の外周側の丸穴12を通過し最下段の外周側から冷気循環のOUT側へ引き込まれる構造になっている。試薬取り出し口1では保冷庫の中央付近では、吹き出しが強く、外周側では、OUT側の引き込みが強く吸込み状態になる。しかし、図2のような、空冷式保冷庫の冷気循環のOUT側の近傍、好ましくは試薬取り出し口1との間に外気導入孔2を設けることで、OUT側の引き込みが弱くなり、試薬取り出し口1での気圧差を軽減でき、冷気循環のIN側から試薬ボトル収納庫3に入ってきた冷気は試薬取り出し口1では、全ては吹き出し状態にできるため、外気侵入により生じる試薬ボトル収納庫3の結露を防止できる。
Usually, the inside of the reagent cooler is kept at 5 to 15 degrees. When hot and humid outside air enters from the reagent take-out port 1 of the reagent cooler cover and contacts the cooled back of the cover, dew condensation occurs when the temperature of the outside air drops and falls below the dew point. As shown in FIG. 1, in an air-cooled refrigerating chamber with closed air circulation, the cold air circulation in the refrigerating chamber is directed from the inner periphery toward the outer periphery at several reagent outlets 1 provided on the reagent refrigerating chamber cover. Therefore, a difference in atmospheric pressure is generated, and the cold air blowing side and the outside air introducing side are divided on the inner peripheral side and the outer peripheral side. FIG. 4 shows a top view of the present invention. From the top view, the cool box is circular. The cool box includes a cold air circulation section including a reagent storage section that stores a reagent container and a partition wall 8 that is provided below and separates an inner periphery and an outer periphery. In the cool air circulation section, the cool air introduced from the IN side of the cooler passes through the square hole 9 in the outer periphery of the center ring and the round hole 11 in the middle partition plate 10 and passes through the round hole 12 on the outer periphery side of the partition plate 10. The structure is drawn from the outer peripheral side of the lowermost stage to the OUT side of the cold air circulation. At the reagent outlet 1, the blowout is strong near the center of the cool box, and the OUT side is strongly drawn on the outer peripheral side and the suction state is established. However, by providing the outside air introduction hole 2 in the vicinity of the OUT side of the cold air circulation of the air-cooled cool box as shown in FIG. 2, preferably between the reagent take-out port 1, the drawing out on the OUT side becomes weak, and the reagent is taken out. The pressure difference at the mouth 1 can be reduced, and all the cold air that has entered the reagent bottle storage 3 from the IN side of the cold air circulation can be blown out at the reagent outlet 1, so that the reagent bottle storage 3 generated by the intrusion of outside air. Condensation can be prevented.

試薬取り出し口1からの吹き出しを全吹き出しにする方法としては、保冷庫の仕切りを円の中央に設置し、OUT側をIN側の180度反対側に配置することでも実現できるが、装置のコンパクト化に影響するためあまり現実的ではない。   As a method for making all the air bubbles from the reagent outlet 1 to be air bubbles, it can be realized by installing the partition of the cold storage in the center of the circle and arranging the OUT side 180 degrees opposite to the IN side. It is not so realistic because it affects

試薬保冷庫カバーの試薬取り出し口1の上面では、外気と接触するために結露が生じる。その対応策として、図3に示す壁4を試薬取り出し口1の周囲に設け、冷気が壁を越えた所で外気と接触し、壁4の外側で結露させて、試薬取り出し口1からの流入を防止した。また、試薬ボトル交換時に試薬取出し用ドア5を開閉する際の結露水の滴下を防止するため、試薬取出し用ドア5の周囲の吸湿材6を設置し、且つ、吸湿材6の自然蒸発の範囲を超えた結露水に関しては、強制的に廃液するためのドレン孔7を設け保冷庫内全体での結露水の発生を防止できる。   On the upper surface of the reagent outlet 1 of the reagent cooler cover, condensation occurs due to contact with the outside air. As a countermeasure, a wall 4 shown in FIG. 3 is provided around the reagent take-out port 1, and the cold air contacts the outside air at a place beyond the wall and is condensed on the outside of the wall 4. Prevented. In addition, in order to prevent the condensation water from dripping when the reagent removal door 5 is opened and closed when the reagent bottle is replaced, a moisture absorbent 6 around the reagent removal door 5 is installed, and the natural evaporation range of the moisture absorbent 6 Condensed water exceeding the range can be provided with a drain hole 7 for forcibly draining liquid to prevent the formation of condensed water in the entire cool box.

従来の試薬保冷庫を用いた場合は、結露水による試薬の薄まりや劣化の影響により、測定値が低下し正しいデータを得ることができない。それに対し、本発明の試薬保冷庫を用いた場合にはそのような影響を受けないため、常に安定したデータを得ることができた。   When a conventional reagent cooler is used, the measured value decreases due to the influence of thinning or deterioration of the reagent due to condensed water, and correct data cannot be obtained. On the other hand, when the reagent cool box of the present invention is used, since it is not affected by this, stable data can always be obtained.

本発明による試薬保冷庫の説明図。Explanatory drawing of the reagent cooler by this invention. 本発明による実施例の説明図。Explanatory drawing of the Example by this invention. 本発明による試薬取り出し口及び試薬取出し用ドアの説明図。Explanatory drawing of the reagent extraction port and reagent extraction door by this invention. 本発明による試薬保冷庫の上面図。The top view of the reagent cooler by this invention.

符号の説明Explanation of symbols

1…試薬取り出し口、2…外気導入孔、3…試薬ボトル収納庫、4…壁、5…試薬取出し用ドア、6…吸湿材、7…ドレン孔、8…仕切り壁、9…中央のリング外周部の角穴、10…中段の仕切り板、11…丸穴、12…外周側の丸穴。

DESCRIPTION OF SYMBOLS 1 ... Reagent extraction port, 2 ... Outside air introduction hole, 3 ... Reagent bottle storage, 4 ... Wall, 5 ... Reagent removal door, 6 ... Hygroscopic material, 7 ... Drain hole, 8 ... Partition wall, 9 ... Center ring Square holes on the outer periphery, 10 ... partition plates in the middle stage, 11 ... round holes, 12 ... round holes on the outer periphery side.

Claims (3)

複数の試薬容器を載置する試薬収容部と、
該試薬収容部に隣接し、冷却器からの冷気を導入する冷気導入室と、該冷却器に冷気を戻す冷気排出室を備えた冷気循環部と、
該冷気導入室から前記試薬収容部に冷気を導入する冷気導入口と、
前記試薬収容部から前記冷気排出室に冷気を排出する冷気排出口と、
前記冷気排出室の前記冷却器の近傍に、外気を該冷気排出室に導入する外気導入口と、
を備えた試薬保冷庫を具備することを特徴とする自動分析装置。
A reagent container for mounting a plurality of reagent containers;
A cool air introduction section that is adjacent to the reagent storage section and that introduces cool air from a cooler; a cold air circulation section that includes a cool air discharge chamber that returns cool air to the cooler;
A cold air inlet for introducing cold air from the cold air introduction chamber into the reagent container;
A cold air outlet for discharging cold air from the reagent container to the cold air discharge chamber;
In the vicinity of the cooler in the cool air discharge chamber, an outside air inlet for introducing outside air into the cool air discharge chamber;
An automatic analyzer comprising a reagent cooler provided with
請求項1記載の自動分析装置において、
前記試薬収容部の上蓋部に設けられた試薬取り出し口の周囲を囲む壁部を備えたことを特徴とする自動分析装置。
The automatic analyzer according to claim 1, wherein
An automatic analyzer comprising a wall portion surrounding a reagent outlet provided in an upper lid portion of the reagent storage portion.
請求項1または2記載の自動分析装置において、
前記試薬収容部の上蓋の試薬取出し用ドアに吸湿材を有し、更に余剰結露水を廃液するドレン孔を有することを特徴とする自動分析装置。
The automatic analyzer according to claim 1 or 2,
An automatic analyzer having a moisture absorbing material in a reagent removal door on an upper lid of the reagent storage unit and further having a drain hole for draining excess condensed water.
JP2004270659A 2004-09-17 2004-09-17 Automatic analyzer Expired - Lifetime JP4248470B2 (en)

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JP2008096201A (en) * 2006-10-10 2008-04-24 Sysmex Corp Analyzer
JP2010091427A (en) * 2008-10-08 2010-04-22 Toshiba Corp Automatic analyzing device, and lid driving method of storage thereof
JP2010230560A (en) * 2009-03-27 2010-10-14 Toshiba Corp Automatic analyzer
JP2010276555A (en) * 2009-05-29 2010-12-09 Toshiba Corp Autoanalyzer
JP2012112730A (en) * 2010-11-22 2012-06-14 Toshiba Corp Autoanalyzer
JP2014002001A (en) * 2012-06-18 2014-01-09 Hitachi High-Technologies Corp Automatic analyzer
JP2014211396A (en) * 2013-04-19 2014-11-13 和光純薬工業株式会社 Water removing device
CN110360795A (en) * 2018-03-26 2019-10-22 成都深迈瑞医疗电子技术研究院有限公司 Reagent pot cover and sample reagent loading attachment

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008096201A (en) * 2006-10-10 2008-04-24 Sysmex Corp Analyzer
JP2010091427A (en) * 2008-10-08 2010-04-22 Toshiba Corp Automatic analyzing device, and lid driving method of storage thereof
JP2010230560A (en) * 2009-03-27 2010-10-14 Toshiba Corp Automatic analyzer
JP2010276555A (en) * 2009-05-29 2010-12-09 Toshiba Corp Autoanalyzer
JP2012112730A (en) * 2010-11-22 2012-06-14 Toshiba Corp Autoanalyzer
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CN110360795A (en) * 2018-03-26 2019-10-22 成都深迈瑞医疗电子技术研究院有限公司 Reagent pot cover and sample reagent loading attachment

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