JP2006006484A - Intraocular lens - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a one-piece type intraocular lens having a new structure, which is a foldable type intraocular lens being integrally formed of a flexible material, stabilizes the deformed shape of a supporting section under an implanted state, and can position and hold an optical section accurately by pressing the optical section to the internal surface on the retina side of a pocket. <P>SOLUTION: Peripheral grooves 28, 30 and 32 which extend circumferentially on the front surface 26 of a supporting section 14 are formed. The supporting section 14 bends at the formed sections of the peripheral grooves 28, 30 and 32 by utilizing the contact reaction force to the internal surface of the pocket at the distal end section of the supporting section 14 under an ophthalmic interposed state. Also, the peripheral grooves 28, 30 and 32 are deformed in the groove width direction just like being crushed, and both wall internal surfaces 46 and 48 in the groove width direction come into contact with each other. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a one-piece type intraocular lens in which an optical part and a support part are integrally formed of a soft material, and can be compacted by being deformed by folding or winding so as to be inserted into the eye. is there.

  Conventionally, in surgery such as cataract, after removing the lens in the capsule through the incision provided in the eye tissue such as cornea (capsular) and anterior lens capsule, the intraocular lens that replaces the lens is removed, A technique of inserting into the eye through the incision and placing it in the sac has been adopted.

  In general, an intraocular lens used in such a cataract surgery is composed of an optical part and a support part. The optical part is substantially circular when viewed from the front, and its central part is a lens region having optical characteristics for providing desired visual acuity. On the other hand, the support portion is formed to extend from the optical portion toward the outer peripheral side, and the tip portion is brought into contact with the inner surface of the outer peripheral portion of the sac under insertion into the eye, thereby It is positioned and held in the sac.

  By the way, when the intraocular lens is inserted into the eye, it is desirable to make the incision portion provided in the eye tissue as small as possible. Therefore, in recent years, ultrasonic lens emulsification and aspiration techniques have been adopted in which the lens is sucked and removed from the sac through a small incision of 2 to 3 mm or less. However, even if the lens can be removed from the small incision, if the larger incision is required when the intraocular lens is subsequently inserted into the sac, the advantage of ultrasonic phacoemulsification cannot be obtained.

  That is, an intraocular lens that is inserted into the eye after removal of the lens generally has an outer diameter of the optical portion of about 6 mm. Therefore, if the intraocular lens is inserted into the eye as it is, It is necessary to widen the incised wound to remove it. Therefore, in recent years, a foldable type eye has been constructed in which an optical part is formed of a soft material that is flexible and easily deformable, and can be inserted into the eye from a small incision while being folded and rolled up to be compact. Inner lenses are being developed and offered.

  However, such a foldable type intraocular lens has a new problem that the optical portion is easily deformed by an external force for positioning applied in an implanted state. That is, as a result of the insertion of the intraocular lens into the sac and the subsequent contraction of the sac, the intraocular lens implanted in the sac is subjected to an external force against the support part abutted against the outer peripheral inner surface of the sac. The abutting reaction force is applied. Further, in the three-piece type foldable type intraocular lens conventionally employed, the rigidity of the support portion is increased as compared with the optical portion. For this reason, the contact reaction force of the support portion against the inner surface of the sac is exerted on the optical portion, and deformation of the optical portion made of a very soft material tends to be a problem.

  Therefore, in recent years, it has been studied to form a whole piece including the optical part and the support part with a soft material to be a one-piece type. Thus, when the whole intraocular lens is integrally formed of a soft material, the manufacture thereof is facilitated, and there is an advantage that the structure is simplified.

  However, when the intraocular lens is integrally formed of a soft material, if the support part is formed of the same material as the soft optical part so that it can be folded and rolled up, it will be transferred to the inner surface of the sac at the distal end in the implanted state. Due to the external force exerted by the contact, the support portion itself is easily deformed irregularly. In particular, since the entire support portion is formed of a soft material and extends outward from the optical portion, deformation when an external force is applied suddenly occurs like buckling, and the position of the deformation It is difficult to predict the degree and mode. Therefore, there is a problem that it is difficult to stably obtain the support form and the support position of the optical part by the support part.

  In order to cope with such problems, it is conceivable to make the support part thick. However, if the rigidity of the support part is increased to such an extent that deformation is prevented, the contact reaction force of the support part on the inner surface of the sac Is directly applied to the optical part. As a result, there is a contradiction that a large deformation occurs in the optical part formed of a soft material, which is not always an effective measure.

  Further, as prior art of the present invention, there are US Pat. No. 5,716,403 (Patent Document 1) and US Patent Publication No. 2003-0204257 (Patent Document 2). In the intraocular lens described in the former (Patent Document 1), an elbow (elbow joint) is provided near the base end side (connecting side with the optical part) of the support part, and the support part is provided at the site. It is easy to bend inward (in the direction of approach to the optical part). The latter (Patent Document 2) proposes an intraocular lens in which a thin part is formed on the base end side of the support part and a thick part is formed outside the thin part.

  In any such U.S. patent structure, a small-strength portion is provided in a part of the support part and the deformation is concentrated on the part, and the deformation position in the support part is specified. It may be possible. However, there is a problem that the degree of deformation at a small strength portion cannot be predicted. In addition, there is a problem in that the contact reaction force of the support portion against the inner surface of the sac is almost absorbed by the small strength portion and hardly acts on the optical portion by deforming at the small strength portion.

  Due to such problems, the intraocular lenses described in Patent Documents 1 and 2 described above have a problem in that it is difficult to stably position the optical unit in the sac when the intraocular lens is implanted. . Particularly in recent years, it has been considered desirable to hold the optical part against the inner surface of the sac on the retina side for the purpose of suppressing the occurrence of secondary cataract. However, in the intraocular lenses having the conventional structure described in Patent Documents 1 and 2, external force is absorbed by deformation of the small strength portion provided in the support portion, and thus it is difficult to reach the optical portion. There is a problem that it is difficult to press against the sac sufficiently strongly.

  On the other hand, Japanese Patent Application Laid-Open No. 8-332194 (Patent Document 3) discloses a structure in which the entire support portion is bent into a bellows shape. However, it is difficult to say that the position and degree of deformation are always stable even if the support portion is bellows-like. In addition, since the support portion is easily deformed so as to expand unpredictably toward either the retinal side or the cornea side, the optical part of the intraocular lens is placed on the inner side of the retinal side of the sac. There is a problem that it is practically impossible to press firmly and stably.

  Furthermore, Japanese Patent Publication No. 9-501856 (Patent Document 4) also discloses an intraocular lens in which an optical part and a support part are integrally formed. However, the intraocular lens disclosed in this gazette is made of a rigid or semi-rigid material, so that the support portion is bent and deformed by utilizing the change in external force accompanying the relaxation of the ciliary muscle, and the optical lens It is only what positively displaced the part in the optical axis direction within the sac. Therefore, such an intraocular lens is completely different from the present invention based on a foldable lens formed of a soft material, and the optical part of the intraocular lens is placed on the inner surface of the retinal side of the sac. Even pressing firmly and firmly is never possible.

US Pat. No. 5,716,403 US Patent Publication No. 2003-0204257 JP-A-8-332194 JP-T 9-501856

  Here, the present invention has been made in the background as described above, and the problem to be solved is a foldable type intraocular lens integrally formed of a soft material, and its support The abutment reaction force against the inner surface of the sac of the support part is effectively applied to the optical part while preventing irregular deformation like buckling in the part, and the optical part is applied to the inner surface of the retinal side of the sac It is an object of the present invention to provide a one-piece type intraocular lens having a novel structure that can be firmly pressed and held stably.

  Hereinafter, the aspect of this invention made | formed in order to solve such a subject is described. In addition, the component employ | adopted in each aspect as described below is employable by arbitrary combinations as much as possible. Further, aspects or technical features of the present invention are not limited to those described below, but are described in the entire specification and drawings, or an invention that can be understood by those skilled in the art from those descriptions. It should be understood that it is recognized based on thought.

  That is, the present invention is characterized in that an optical part that includes a lens region having predetermined optical characteristics and is substantially circular in a front view, and extends from the optical part toward the outer peripheral side to the eye. A support portion that holds the optical portion against the inner surface of the retinal side of the sac by being brought into contact with the inner surface of the outer peripheral portion of the sac under insertion, and is folded or In a one-piece intraocular lens integrally formed of a soft material that can be rolled up, a circumferential groove extending in the circumferential direction of the optical unit is formed on the front surface of the support unit that is positioned on the cornea side in an intraocular insertion state. Then, the support portion bends at the peripheral groove forming portion by utilizing an external force exerted by the distal end portion of the support portion being brought into contact with the inner surface of the outer peripheral portion of the sac under insertion in the eye, and The circumferential groove is in the groove width direction. Deformed walls the inner surface of the groove width direction of the circumferential groove as is the fact that is configured to abut against each other.

  In such an intraocular lens having a structure according to the present invention, the optical part is pressed against the inner surface of the retinal side of the sac in the implanted state mainly due to the following (1) to (3). Thus, the positioning is stable. As a result, the foldable intraocular lens that can be inserted into the eye through a small incision, is effective in suppressing secondary cataracts, is easy to manufacture, and is highly practical. This can be realized by integrally molding the materials.

  (1) Under the implanted state, the external force exerted on the support portion is biased by the reaction force against the inner surface of the sac at the portion where the peripheral groove is formed in the support portion, and a bending moment is generated. As a result, the support portion is reliably bent and deformed in the direction where the circumferential groove is formed at the circumferential groove forming portion. Based on the deformation of the support portion, the optical portion is displaced toward the retina in the sac and pressed.

  (2) Under an implanted state in which the support part is bent and deformed, the external force exerted on the support part by the contact reaction force on the inner surface of the sac is transmitted to the optical part through the mutual contact parts on the inner surfaces of both walls of the circumferential groove. Is done. Therefore, excessive deformation is prevented also at the circumferential groove forming portion, and external force is effectively transmitted from the support portion toward the optical portion, and the optical portion is firmly pressed against the retina in the sac.

  (3) The external force caused by the reaction force of the support portion against the inner surface of the sac is reduced by the deformation of the support portion at the circumferential groove forming portion, and is not exerted directly as a large external force on the optical portion. Therefore, the support part is deformed in a specific direction by the circumferential groove, so that the optical part is surely displaced toward the retina side in the sac and pressed against the inner surface of the sac, but the generation of large stress and strain in the optic part is avoided. And good optical properties are ensured.

  Further, in the one-piece type intraocular lens according to the present invention, the support portion has a substantially constant thickness dimension throughout, and the circumferential groove is formed so as to open to the front surface thereof. Therefore, a configuration in which the thickness dimension of the peripheral groove forming portion is made smaller than other portions of the support portion is suitably employed.

  According to such a configuration, the external force due to the contact reaction force of the support portion on the sac inner surface can be stably transmitted from the contact portion of the support portion to the sac inner surface to the peripheral groove forming portion. Therefore, the planned deformation at the circumferential groove forming portion is more stably generated in the support portion, and the positioning of the optical portion can be realized more stably.

  Further, in the one-piece type intraocular lens according to the present invention, at least a tip part of the support part is inclined toward the front side in the optical axis direction of the optical part, and the tip part is inclined to the front side. A configuration extending from the optical part to the outer peripheral side is preferably employed.

  According to such a configuration, the contact reaction force of the support portion on the inner surface of the sac exerted in a direction substantially orthogonal to the central axis of the optical portion is inclined with respect to the extending direction of the support portion from the optical portion. Acts in the direction. As a result, the contact reaction force on the inner surface of the sac generates a moment in a specific direction with respect to the support part, and the optical part is more actively displaced toward the retina side in the sac by the moment, It can be pressed more efficiently against the inner surface of the sac.

  Further, in the one-piece type intraocular lens according to the present invention, the rear surface of the support portion that is positioned on the retina side in the intraocular insertion state has a smooth line without any broken lines or local unevenness over the entire rear surface. A configuration having a continuous surface made of a flat surface or a curved surface is preferably employed.

  According to such a configuration, when the rear surface of the support portion is in contact with the inner surface of the sac in a region extending from the distal end portion toward the proximal end side (optical portion side) under the implanted state of the intraocular lens. In this case, the rear surface of the support portion smoothly contacts the inner surface of the sac. Thereby, local contact stimulation with respect to the inner surface of the sac of the support portion is avoided, and the contact state of the support portion with the inner surface of the sac is further stabilized, thereby further stabilizing the support state of the optical unit. I can do it. Note that a smooth curved surface without a broken line or local unevenness is a curved surface with a single curvature, a curved surface with a gradually changing curvature, or a plurality of connected tangent lines in the extending direction of the support portion. A curved surface or a combination surface of a curved surface and a flat surface.

  Further, in the one-piece type intraocular lens according to the present invention, the front surface of the support portion is a smooth flat surface having no broken line or local unevenness over substantially the whole area excluding the portion where the circumferential groove is formed. A configuration having a continuous surface made of a curved surface is preferably employed.

  According to such a configuration, irregular deformation at a portion other than the circumferential groove in the support portion can be more advantageously prevented, and the desired deformation mode of the support portion at the formation portion of the circumferential groove can be further stabilized. Can be expressed. In particular, the present configuration desirably employs a combination of a configuration in which the rear surface of the above-described support portion is a continuous flat surface or a curved surface over the entire surface. Can be generated more stably.

  In the one-piece type intraocular lens according to the present invention, a configuration in which the peripheral groove in the support portion is formed on a substantially boundary line between the support portion and the optical portion is preferably employed.

  According to such a configuration, the support portion can be curved on the boundary line between the outer peripheral edge portion of the optical portion and the support portion. Therefore, the adhesion to the inner surface of the sac at the outer peripheral edge of the optical part can be obtained more advantageously without being disturbed by the support part extending outward from the outer peripheral edge of the optical part.

  Further, as described above, when forming a circumferential groove on the boundary line between the optical part and the support part, the thickness dimension of the support part side end located across the circumferential groove is the thickness of the optical part side end. The thickness is larger than the dimension, and the thickness of the peripheral groove forming part is smaller than the thickness of the support part side end and the optical part side end. obtain.

  According to such a configuration, it is possible to fold and roll up the optical part more compactly while suppressing the maximum thickness dimension of the optical part while ensuring the rigidity of the support part to the extent that irregular deformation is prevented. At the same time, it is possible to suppress the deformation of the optical part under the implanted state by suppressing the transmission of stress from the support part to the optical part.

  Further, in the one-piece type intraocular lens according to the present invention, at the boundary portion between the optical unit and the support unit, the optical unit positioned on the retina side under the intraocular insertion state and both rear surfaces of the support unit are provided. The structure connected by the smooth surface which has a common tangent is employ | adopted suitably.

  According to such a configuration, there is no shape fold line portion at the boundary between the optical unit and the support unit, and even when the outer peripheral edge of the optical unit is pressed against the inner surface of the retinal side of the sac, the pressing state against the sac inner surface is further increased. It is stably expressed and reduces irritation and adverse effects on the inner surface of the sac. In this aspect, for example, both rear surfaces of the boundary portion between the optical part and the support part are advantageously provided by a curved surface or a flat surface extending with a constant curvature radius or a gradually changing curvature radius in the direction perpendicular to the axis. Composed.

  In the one-piece type intraocular lens according to the present invention, the circumferential groove in the support part is a circular or arcuate groove extending in the circumferential direction on the same central axis as the optical part. Are preferably employed.

  According to such a configuration, coupled with the fact that the support portion is formed of a soft material, the portion where the circumferential groove that is bent in the support portion is formed on the outer side of the optical portion extends in the entire circumferential direction. It is set at a position that is substantially equally spaced from the peripheral edge. That is, when the support portion is formed of a hard material, it is difficult to produce an effective curve unless the groove extends linearly. However, since the support portion is formed of a soft material, a circular or circular shape is not possible. The circumferential groove extending in the circumferential direction in an arc shape makes it possible to form a portion that is curved in the support portion around a substantially central axis of the optical portion. As a result, the optical part can be positioned and supported more stably in the sac by the support part curved at the site where the circumferential groove is formed. In particular, this configuration is advantageously employed in combination with a configuration in which the support portion has a certain width dimension in the circumferential direction of the optical portion.

  Further, in the one-piece type intraocular lens according to the present invention, it is preferable to employ a configuration in which the circumferential groove in the support portion extends in the circumferential direction with a cross-sectional shape gradually expanding from the bottom toward the opening. Is done.

  According to such a configuration, it is possible to ensure a large contact area between the inner surfaces of both walls of the circumferential groove when it is bent while sufficiently securing the ease of bending at the circumferential groove forming portion. Thereby, the contact state of the inner surfaces of both walls of the circumferential groove can be maintained more stably under the implanted state, and the accuracy and stability of the positioning of the optical unit can be further improved. In this configuration, for example, a circumferential groove having an enlarged cross-sectional shape such as a substantially V shape, a letter shape, or a curved shape that is convex in the groove is advantageously employed.

  In the one-piece intraocular lens according to the present invention, the ratio of the projection area: b in the optical axis direction of the support section to the projection area: a in the optical axis direction of the optical section is set to b. A configuration in which /a=0.3 to 3.0 is preferably employed.

  According to such a configuration, the ease of the operation of inserting the intraocular lens into the sac and the positioning stability of the optical unit under the condition of being implanted in the sac can be achieved in a highly compatible manner. If the value of b / a is smaller than 0.3, it is difficult to ensure the strength of the support portion enough to counter the stress exerted on the support portion as the support portion comes into contact with the inner surface of the sac. As a result, the positioning force of the optical unit may be insufficient, or unstable deformation such as buckling may occur. On the other hand, when the value of b / a is larger than 3.0, the support part spreads widely around the optical part, and the incision when the intraocular lens is made small and inserted into the eye becomes too large. There is.

  Further, in the one-piece type intraocular lens according to the present invention, the thickness dimension at the portion where the peripheral groove is formed in the support part: t (min) with respect to the maximum thickness dimension: t (max) in the support part. A configuration in which the value of the ratio is t (min) / t (max) = 0.5 to 0.8 is preferably employed.

  According to such a configuration, the bending deformation around the circumferential groove of the support portion is expressed to be more stable and more advantageous in the implanted state, and the optical portion is positioned and held in the sac. Can be achieved more effectively. If the value of t (min) / t (max) is less than 0.5, the concentration of stress and strain on the peripheral groove forming portion becomes too large, and the strength and durability at the peripheral groove forming portion are too high. There is a risk of hindering securing. On the other hand, if the value of t (min) / t (max) is greater than 0.8, the concentration of stress and strain at the peripheral groove forming portion becomes difficult to be sufficiently exerted, Stress relaxation based thereon is hardly exerted effectively, and as a result, irregular deformation or buckling occurs in the support portion, and the optical portion may not be positioned stably.

  In the one-piece type intraocular lens according to the present invention, a configuration in which the thickness dimension of the support portion is 0.1 to 0.55 mm is suitably employed.

  According to such a configuration, the operation of folding and winding up the support portion is easily performed while suppressing irregular deformation of the support portion under the embedded state and ensuring the positioning accuracy of the optical portion by the support portion. This makes it easier to insert into the eye.

  In the one-piece type intraocular lens according to the present invention, a configuration in which the outer diameter of the optical unit is 3.2 to 6.0 mm is preferably employed.

  According to such a configuration, the accuracy and stability of the positioning of the optical part by the support part can be further advantageously realized in the state of being implanted in the sac. At the same time, the intraocular lens can be made smaller when inserted into the sac and easily inserted through a small incision. Since the size of the human sac is substantially constant, if the outer diameter dimension of the optical part is smaller than 3.2 mm, the length of the support part that extends outward is increased. It is difficult to ensure the shape stability of the optical part, and the optical part positioning stability by the support part may be lowered. Further, in the dark place, there is also a problem that the outer dimension of the optical part becomes smaller than the iris diameter, and the optical part is slightly displaced and glare is likely to occur. On the other hand, if the outer diameter of the optical part exceeds 6.0 mm, it is difficult to fold or roll it down sufficiently, and not only the incision at the time of insertion into the eye increases, but also the effective length of the support part increases. It becomes small and it becomes difficult to secure a sufficient amount of displacement of the optical part in the back of the sac due to the curvature or inclination of the support part, and the optical part may be insufficiently pressed against the inner surface of the retinal side of the sac.

  In the one-piece type intraocular lens according to the present invention, a configuration in which the maximum thickness of the optical unit is 0.1 to 0.75 mm is suitably employed.

  According to such a configuration, the optical unit can be easily folded and rolled up while ensuring the strength or rigidity of the optical unit necessary to ensure stable optical characteristics in the implanted state. The insertion operation into the eye at the time of insertion is further facilitated.

  Further, in the one-piece type intraocular lens according to the present invention, the pair of support portions are formed substantially independently of each other so as to be opposed to each other across the central axis of the optical portion. A configuration in which the circumferential groove is formed for each of the pair of support portions is preferably employed.

  According to such a configuration, the support performance of the optical unit by the support unit, particularly the support performance on the visual axis of the optical center of the optical unit is based on the positioning force exerted on the optical unit via the pair of support units. It can be advantageously secured. At the same time, since a pair of support portions are independently formed on the circumference of the optical portion, characteristics such as positioning strength of the optical portion by the support portion can be adjusted by appropriately adjusting the shape and size of each support portion. Can be appropriately set with a large degree of freedom.

  In the one-piece intraocular lens according to the present invention, a configuration in which a plurality of the circumferential grooves are formed so as to be separated from each other in the extending direction of the support portion is suitably employed.

  According to such a configuration, the degree of bending of the entire support portion is set large while avoiding the concentration of stress and strain on the formation site of one circumferential groove, or the bending of the entire support portion is reduced. Various shapes can be set more freely. Therefore, for example, the amount of displacement in the optical axis rearward direction of the optical part placed in the intraocular insertion state is set to be larger, or the support part is along the inner surface of the sac in a wider area than the inner surface of the sac. Thus, it is possible to make the contact more stably in a close contact state.

  Therefore, in a one-piece type intraocular lens in which a plurality of circumferential grooves are formed, the support portion is bent at each forming portion of the circumferential grooves formed in a plurality of strips in an intraocular insertion state. A configuration in which the rear surface of the support portion is overlapped with and in contact with the inner surface of the sac in a region having a predetermined length from the distal end portion toward the optical portion is preferably employed.

  In addition, the plurality of circumferential grooves formed in the above-mentioned support part include, for example, (a) a proximal-side circumferential groove located on the optical part side from the center in the extending direction of the support part, and (b) the A distal-side circumferential groove located on the distal end side from the center in the extending direction of the support part, and (c) at least one intermediate circumferential groove located between the proximal-side circumferential groove and the distal-side circumferential groove, Including, advantageously.

  By adopting such a form of a plurality of circumferential grooves, while suppressing the transmission of stress and strain of the optical part from the support part sufficiently small by the base end side circumferential groove, by the distal end side circumferential groove and the intermediate circumferential groove, The distal end portion of the support portion can be bent and deformed relatively large over a predetermined length. For example, the distal end portion of the support portion is overlapped over a relatively long area on the inner surface of the sac, so that it is more stable. It is also possible to abut. The formation position of the intermediate circumferential groove may be anywhere between the proximal end side circumferential groove and the distal end side circumferential groove, and does not mean the center of the support portion.

  In the one-piece type intraocular lens according to the present invention, a configuration in which the soft material has a glass transition temperature of 30 ° C. or lower and a refractive index of 1.51 or higher is preferably employed.

  According to such a configuration, the operation of folding or rolling up the intraocular lens can be easily performed, and further compaction can be achieved, and the insertion operation into the eye during insertion can be facilitated. If the glass transition temperature exceeds 30 ° C. or the refractive index exceeds 1.51, folding or winding becomes difficult, and insertion of an intraocular lens from a small incision becomes difficult.

  Furthermore, the present invention is a positioning structure for a one-piece type intraocular lens having a structure according to the present invention as described above, wherein the distal end portion of the support portion is brought into contact with the inner surface of the outer peripheral portion of the sac under insertion into the eye. The supporting portion is bent and deformed at the portion where the circumferential groove is formed by utilizing an external force exerted by contact, and the circumferential groove is deformed so as to be crushed in the groove width direction. By causing the inner surfaces of the walls to contact each other, the external force exerted on the support portion through the contact portions of the inner surfaces of both walls of the circumferential groove is transmitted in the extending direction of the support portion to act on the optical portion. The positioning structure of the intraocular lens that positions the optical unit so as to press the inner surface of the sac on the retina side is also a feature.

  According to such a positioning structure of the present invention, the support portion can be stably curved and deformed in a predetermined shape under the implanted state even though it is a foldable type intraocular lens that is an integrally molded product of a soft material. At the same time, the contact reaction force of the support portion against the inner surface of the sac is effectively exerted on the optical portion through the support portion. Accordingly, the optical unit can be stably positioned in a state where the optical unit is displaced by a predetermined amount to the retinal side in the sac and the optical unit is pressed against the inner surface of the retinal side of the sac.

  As is clear from the above description, in the one-piece type intraocular lens having a structure according to the present invention, the target portion is formed by the action of the circumferential groove in the implanted state inserted into the eye capsule. Therefore, an appropriate positioning force is exerted on the optical unit. Accordingly, the optical unit can be stably positioned in a state where the optical unit is pressed against the inner surface of the retinal side of the sac.

  Therefore, according to the present invention, a foldable type eye that can be inserted into the eye from a small incision, is effective in suppressing secondary cataracts, is easy to manufacture, and has excellent practicality. The inner lens can be advantageously realized by an integrally molded product of soft material.

  Hereinafter, in order to clarify the present invention more specifically, embodiments of the present invention will be described in detail with reference to the drawings.

  1 and 2 are a front view and a longitudinal sectional view of a foldable type intraocular lens 10 as an embodiment of the present invention. The intraocular lens 10 includes an optical unit 12 and a pair of support units 14 and 14.

  In addition, the intraocular lens 10 having the optical part 12 and the support parts 14 and 14 as described above is excellent in addition to having a visible light transmittance sufficient to give a foldable type intraocular lens. It can be made of various materials with softness and a certain degree of elasticity. Preferably, it is formed of a soft material having a glass transition temperature of 30 ° C. or lower and a refractive index of 1.51 or higher. With such a soft material, the intraocular lens 10 can be easily folded or rolled up at room temperature to be more compact, and can be more easily inserted into the eye during implantation. .

  Specifically, those described in JP-A-10-24097 and JP-A-11-56998 are suitably employed as the molding material for the intraocular lens 10 according to the present invention. Among them, in order to obtain an intraocular lens having excellent shape recoverability, it is desirable to employ a monomer containing one or more (meth) acrylic acid esters as shown in (i) below. Moreover, arbitrary monomers as shown in the following (ii) are appropriately blended. Furthermore, an additive as shown in the following (iii) is added if necessary.

(I) Containing monomer The linear, branched or cyclic alkyl (meth) acrylates as follows:
Methyl (meth) acrylate, ethyl (meth) acrylate, butyl (meth) acrylate, cyclohexyl (meth) acrylate, etc. Hydroxyl group-containing (meth) acrylates as follows:
Hydroxyethyl (meth) acrylate, hydroxybutyl (meth) acrylate, diethylene glycol mono (meth) acrylate, etc. Aromatic ring-containing (meth) acrylates such as the following:
Phenoxyethyl (meth) acrylate, phenyl (meth) acrylate, phenylethyl (meth) acrylate, etc. Silicon-containing (meth) acrylates such as the following:
Trimethylsiloxydimethylsilylmethyl (meth) acrylate, trimethylsiloxydimethylsilylpropyl (meth) acrylate, etc. Note that “(meth) acrylate” is a generic term for the two compounds “... acrylate” and “... methacrylate”. The same applies to other (meth) acrylic derivatives described later.

(Ii) Arbitrary monomer (Meth) acrylamide or a derivative thereof as follows:
(Meth) acrylamide, N, N-dimethyl (meth) acrylamide, etc. N-vinyllactams such as the following:
N-vinylpyrrolidone, etc. Styrene or its derivatives Crosslinkable monomers as follows:
Butanediol di (meth) acrylate, ethylene glycol di (meth) acrylate

(Iii) Additive Thermal polymerization initiator, photopolymerization initiator, photosensitizer, etc. Pigment, etc. Ultraviolet absorber, etc.

  In addition, when the intraocular lens 10 as shown in the figure is integrally molded using such a monomer material, any conventionally known various methods can be employed, for example, a cutting molding method or a molding method. Thus, the target intraocular lens 10 can be obtained. According to the cutting molding method, a predetermined polymerization component composed of the monomer material as described above is polymerized to form a lens blank having an appropriate shape such as a rod shape, a block shape, or a plate shape, and then applied using a lathe or the like. By cutting the lens blank, the intraocular lens 10 having a desired shape can be obtained. Also, according to the molding method, a predetermined polymerization component made of the monomer material as described above is introduced into the molding cavity using a molding die having a molding cavity corresponding to the shape of the target intraocular lens 10. Then, by performing an appropriate polymerization operation there, an intraocular lens 10 having a desired shape can be obtained. In addition, as a polymerization method of the monomer material, a conventionally known thermal polymerization method, photopolymerization method, a polymerization method combining them, or the like is appropriately employed depending on the monomer material.

  In the intraocular lens 10 integrally molded as described above, the optical portion 12 has a substantially disk shape with a circular front view. The central portion of the optical unit 12 or the entire region thereof is a lens region having optical characteristics that perform an alternative function of the crystalline lens of a human eye. The lens surface (front surface 16 and rear surface 18) of the optical unit 12 can have various shapes according to the required optical characteristics, and the shapes of both surfaces 16, 18 can be any combination of concave, convex, flat surfaces, etc. Is set. In the present embodiment, a convex lens-shaped optical unit 12 in which both the front surface 16 and the rear surface 18 are spherical convex surfaces is employed.

  Here, the outer diameter dimension D of the optical unit 12 is preferably 3.2 to 6 mm, and more preferably 3.5 to 4.6 mm. The optical unit 12 needs to have an appropriate size so that it can effectively function as a human crystalline lens. In addition, since the size of the sac of a person inserted with the intraocular lens 10 in the accommodated state is substantially constant, if the outer diameter of the optical part 12 is smaller than 3.2 mm, the support parts 14 and 14 become longer. However, if the outer diameter of the optical part 12 is larger than 6 mm, the support parts 14 and 14 become too short, and the buffering action of the external force described later and the rear displacement amount of the optical part 12 are likely to occur. Etc. may be difficult to obtain.

  Further, it is desirable that the thickness dimension (thickness): T in the optical axis direction (left-right direction in FIG. 2) of the optical unit 12 is a maximum value of 0.1 to 0.75 mm, and more preferably. The maximum value is 0.25 to 0.50 mm. When the maximum thickness value of the optical part 12 is less than 0.1 mm, the shape maintaining performance of the optical part 12 under the embedded state may not be stably exhibited. If the maximum value of the wall thickness dimension exceeds 0.75 mm, it may be difficult to fold or wind up the optical unit 12 sufficiently small during insertion into the sac. In the present embodiment, the optical unit 12 has a biconvex shape, and has a maximum thickness on the optical axis that is the geometric center. The specific value of the maximum wall thickness dimension T is designed in consideration of the characteristics of the material to be used (softness and the like) and the shape and size of the optical unit 12 in a comprehensive manner.

  On the other hand, the pair of support portions 14 and 14 have the same shape and are located on both sides of the optical portion 12 in one radial direction (the vertical direction in FIG. 1). The support portions 14 and 14 are integrally formed with the optical portion 12 so as to extend radially outward from the outer peripheral edge portion of the optical portion 12 toward the outer peripheral side.

  The support portions 14 and 14 are more preferably 8.5 to 13.5 mm so that the distance L between the front end surfaces 19 and 19 in the extending direction of the support portions 14 is preferably 8 to 14 mm. The protrusion length is set in consideration of the outer diameter dimension of the optical unit 12. Accordingly, the size of a general human sac is adapted, and the intraocular lens 10 including the optical unit 12 can be advantageously positioned in the sac.

  Particularly in the present embodiment, each support portion 14 extends as a whole from the outer peripheral edge portion of the optical portion 12 with a slight inclination toward one side in the optical axis direction. The inclination direction is the front surface 16 side with respect to the axis-perpendicular direction line of the optical unit 12, in other words, the surface side that is positioned on the cornea side when the intraocular lens 10 is implanted.

  Moreover, each support part 14 is made into the substantially constant thickness dimension over the whole, and the thickness dimension: t is substantially the same as the thickness dimension of the outer periphery part of the optical part 12. As shown in FIG. Further, the support part 14 extends outward from the outer peripheral edge part of the optical part 12 with a width dimension extending in a predetermined width in the circumferential direction of the optical part 12. The thickness dimension t of the support portion 14 is preferably 0.1 to 0.55 mm, more preferably 0.20 to 0.55 mm, and even more preferably 0.25 to 0.50 mm. If the thickness of the support part 14 is less than 0.1 mm, the optical part 12 may be irregularly deformed in the implanted state, making it difficult to position the optical part 12 stably. If the thickness exceeds 0.55 mm, it may be difficult to fold or roll up the support portion 14 sufficiently small when inserted into the sac.

  In general, the thickness of the support portion 14 is set so that the maximum value does not exceed the maximum thickness of the optical portion 12. In particular, in this embodiment, the maximum thickness of the support portion 14 is set to be equal to or smaller than the thickness of the outer peripheral edge of the optical portion 12. Accordingly, it is possible to relax the transmission of the external force exerted in the implanted state to the optical unit 12 and to position the optical unit 12 advantageously without making the support unit 14 unnecessarily thick. . In addition, the thickness dimension of the outer periphery part of the optical part 12 shall mean the thickness dimension of the part in which the support part 14 is not formed in the outer periphery of the optical part 12. FIG.

  Furthermore, the width dimension of the support part 14 has a length of about a half or less in the circumferential direction of the optical part 12 at the base end part connected to the optical part 12, and the distal end side in the extending direction. The width dimension gradually becomes smaller as it goes to. As shown in FIG. 1, both side surfaces 20, 20 of the support portion 14 in the width direction gradually approach each other with curved surfaces that are slightly convex outward. The front end surface 19 in the extending direction of the support portion 14 is also an arcuate curved surface extending in the circumferential direction on the same central axis as the optical portion 12.

  The size of the support portion 14 is determined at the proximal end portion connected to the optical portion 12 in consideration of the strength and durability at the connection portion with the optical portion 12 and the positioning force in the sac 24 of the optical portion 12. In the circumferential direction of the optical unit 12, it is desirable to set it to 1/12 or more, more preferably 1/6 to 1/2. Further, the distal end surface 19 of the support portion 14 has a width dimension equal to or larger than 1/4 of the outer diameter dimension D of the optical section 12 in order to ensure a sufficient contact area with the inner surface of the sac 24 in the circumferential direction. Desirably, the width dimension is more preferably ½ or more.

In addition, the size of the support portion 14 is desirably set so as to satisfy the following expression with respect to the optical portion 12. However, in the following formula, a is the projected area in the optical axis direction of the optical unit 12, and b is the projected area in the optical axis direction of the entire pair of support units 14 and 14.
0.3 ≦ b / a

  When the value of b / a in the above formula is smaller than 0.3, the external force exerted during insertion is not easily relaxed by deformation of the support part 14 and the optical part 12 is greatly distorted. Or the local distortion of the support part 14 becomes too large, and there is a possibility that the positioning accuracy with respect to the optical part 12 is lowered due to the buckling deformation. More preferably, it is set so as to satisfy 0.4 ≦ b / a. More preferably, it is set so that b / a ≦ 3.0. If the support part 14 becomes too large with respect to the optical part 12, the rigidity of the support part 14 may become too large.

  Furthermore, the rear surface 22 of the support portion 14 has a smooth surface shape that extends from the outer peripheral edge to the tip of the optical portion 12 without having a fold point or a fold line. In addition, the rear surface 22 of the support part 14 means the surface where the intraocular lens 10 is positioned on the retina side in the implanted state where the intraocular lens 10 is inserted into the sac 24 as shown in FIG. In addition to a flat surface, a smooth surface that does not have a break point or a broken line is a spherical surface or an arc-shaped curved surface having a constant curvature radius, or a two-dimensional or three-dimensional curved surface having a curvature radius that changes with a common tangent. including.

  Specifically, the curvature radius and the extending direction of the rear surface 22 of the support portion 14 are set so that both rear surfaces 18 and 22 are connected with a common tangent at the boundary portion between the optical portion 12 and the support portion 14. Yes. For example, if the rear surface 18 of the optical unit 12 is a spherical surface having a certain radius of curvature, the rear surface 22 of the support unit 14 is also preferably formed as a part of a spherical surface having the same center point and curvature radius as the rear surface 18 of the optical unit 12. Is done. Alternatively, the rear surface 22 of the support portion 14 is suitably formed as a part of a frustoconical surface (tapered cylindrical surface) extending in a tangential direction from the outer peripheral edge portion of the rear surface 18 of the optical unit 12 or a flat surface.

  In particular, as shown in the figure, when the rear surface 22 of the support portion 14 is a partial spherical surface, the radius of curvature is preferably 20 to 80 mm. Thereby, under the implantation state of the intraocular lens 10, a favorable contact state with respect to the inner surface of the sac 24 of the support portion 14 is expressed, and more effective positioning and holding can be performed.

  On the other hand, the front surface 26 of the support portion 14 is preferably formed so as to expand in a surface shape substantially similar to the rear surface 22. On the front face 26, three circumferential grooves 28, 30, and 32 are formed. These circumferential grooves are located at a predetermined distance from each other in the extending direction of the support portion 14, and serve as a proximal end side circumferential groove 28, an intermediate circumferential groove 30, and a distal end side circumferential groove 32.

  The proximal-side circumferential groove 28 extends in the circumferential direction along the boundary portion between the optical unit 12 and the support unit 14. The intermediate circumferential groove 30 extends in the circumferential direction at a substantially central portion in the extending direction of the support portion 14. The distal end side circumferential groove 32 extends in the circumferential direction near the distal end edge in the extending direction of the support portion 14. In particular, in the present embodiment, the separation distance between the intermediate circumferential groove 30 and the distal end side circumferential groove 32 is set smaller than the separation distance between the intermediate circumferential groove 30 and the proximal end circumferential groove 28.

  In the present embodiment, the three circumferential grooves 28, 30, and 32 are all formed in a substantially constant cross-sectional shape over the entire length in the width direction of the support portion 14. Each of the circumferential grooves 28, 30, and 32 is formed to be curved in the width direction of the support portion 14 so as to extend on a circumference that is substantially centered on the optical center axis of the optical portion 12.

  Here, the cross-sectional shapes of the circumferential grooves 28, 30, and 32 do not need to be the same, and the sizes may be different from each other. Several specific examples of the cross-sectional shape suitably employed as the circumferential grooves 28, 30, and 32 are shown in FIGS. Each of the circumferential grooves shown in FIGS. 4 to 8 is appropriately used for any of the three circumferential grooves 28, 30, and 32 in the present embodiment. In FIG. 8, each circumferential groove is given a different symbol.

  The circumferential groove 34 shown in FIG. 4 has a rectangular cross section and is formed so that both side walls rise from a flat bottom with a substantially constant groove width dimension and open to the front surface 26 of the support portion 14. Has been.

  Each of the circumferential groove 36 shown in FIG. 5 and the circumferential groove 38 shown in FIG. 6 is substantially wedge-shaped or triangular in cross section, and faces the opening side of the front surface 26 of the support portion 14. It is gradually expanded. In particular, the circumferential groove 36 shown in FIG. 5 has an isosceles triangular cross section that expands equally on both sides from the bottom of the deepest point toward the opening. On the other hand, the circumferential groove 38 shown in FIG. 6 has one side wall extending substantially perpendicularly from the front surface 26 and the other side wall extending obliquely from the deepest bottom to one side toward the opening. It has a right-angled triangular cross section.

  The circumferential groove 40 shown in FIG. 7 and the circumferential groove 42 shown in FIG. 8 are both opened from the bottom of the deepest point so that the groove width dimension gradually increases toward the opening. It has an irregular cross-sectional shape that expands toward the surface. In particular, the circumferential groove 40 shown in FIG. 7 has a curved shape in which the side walls on both sides thereof protrude inward. On the other hand, the circumferential groove 42 shown in FIG. 8 has a curved shape in which one side wall extends linearly and only the other side wall protrudes inward.

  Further, these circumferential grooves 34, 36, 38, 40, 42 have a depth dimension: d of 0.2 to 0.5 times the maximum thickness dimension value of the support portion 14: t (max). It is desirable that As a result, the strength and durability of the support portion 14 are advantageously ensured even at the site where the circumferential groove is formed, and the shape stability and the like of the support portion 14 when an external force is exerted in an implanted state are further advantageous. Secured.

  The intraocular lens 10 having the above-described structure can be reduced in size by being folded or rolled up in an appropriate direction including the optical unit 12 and the support units 14 and 14. The Then, as is well known, a part of the human eye capsule 24 is incised, and after removing the crystalline lens by suction or the like, the reduced size intraocular lens 10 is passed through the incision. Insert into the sac 24. This insertion operation is performed using an appropriate insertion tool as necessary.

  Since the foldable type intraocular lens is formed of a soft material, it easily deforms when an external force is applied during insertion, and it is difficult to insert the foldable type intraocular lens into the sac 24 in a stable shape. There is a case. In this embodiment, for example, the intraocular lens 10 can be easily inserted into the sac 24 by using an insertion tool having a distal end portion that can be hooked in the circumferential grooves 28, 30, and 32. .

  That is, as illustrated in FIG. 9A, the intraocular lens 10 is folded in an appropriate direction, and the distal end portion 45 of the insertion tool 44 is inserted while being hooked on the circumferential groove 32 of the one support portion 14. By operating the tool 44, the support part 14 to which the insertion tool 44 is locked is positioned forward, and the optical part 12 and the other support part 14 are pulled by the support part 14 and pulled into the eye. Can be inserted. As a result, the intraocular lens 10 is inserted into the sac 24 without touching the optical unit 12 while maintaining a predetermined shape while minimizing the deformation of the optical unit 12 and the support units 14 and 14. It becomes possible.

  In addition, it is also possible to employ | adopt the insertion tool provided with the front-end | tip part latched in the circumferential location 28, 30 and 32 with respect to the circumferential grooves 28, 30, and 32 formed in the support part 14 of the intraocular lens 10. FIG. Thereby, the intraocular lens 10 can be inserted into the eye more stably. Specifically, for example, as shown in FIG. 9B, with respect to the circumferential grooves 28 and 28 of the support portions 14 and 14 positioned on the front side and the rear side in the insertion direction of the intraocular lens 10, An insertion tool 47 having a pair of tip portions 45, 45 that are respectively hooked can be employed.

  A treatment method for inserting an intraocular lens into the eye using such a circumferential groove is described later in addition to the intraocular lens 10 having a pair of plate-like support portions 14 and 14 as in the present embodiment. The present invention can be similarly applied to an intraocular lens (see FIG. 12) having an annular support portion. Furthermore, in an intraocular lens (see FIG. 11) provided with a substantially loop-shaped support portion to be described later, the intraocular lens can be inserted into the eye by pushing the optical unit 12 directly from the rear. As described above, the treatment may be performed using an insertion tool hooked in the circumferential groove. In particular, even in the case of an intraocular lens having a substantially loop-shaped support portion, when the connecting portion of the support portion to the optical portion extends over a quarter or more in the circumferential direction of the optical portion, the optical It is difficult to insert the eye part directly into the eye, but even in that case, it can be easily and shaped by inserting it into the eye by pulling the optical part using the insertion tool hooked on the circumferential groove. Treatment can be performed while maintaining stability.

  Thus, as shown in FIG. 3, the intraocular lens 10 implanted so as to be entirely accommodated in the sac 24 has an initial shape based on its own elasticity in the sac 24. Spread to restore. As shown in FIG. 3, the optical unit 12 is expanded with respect to the central axis of the eye optics by expanding and positioning the intraocular lens 10 in the sac 24 using an appropriate instrument as required. The intraocular lens 10 is positioned with respect to the sac 24 so that their optical axes substantially coincide.

  Under such an implanted state of the intraocular lens 10, the distance L between the distal end surfaces 19 and 19 of the support portions 14 and 14 in the intraocular lens 10 is set to be larger than the inner diameter dimension of the sac 24. For this reason, the front end surfaces 19 and 19 of the support portions 14 and 14 are in close contact with and in contact with the outer peripheral inner surface of the sac 24. At this time, the support portions 14 and 14 receive a contact reaction force from the sac 24, and the support portions 14 and 14 are deformed by the contact reaction force.

  Here, each support part 14 is inclined from the beginning toward the front (right side in FIG. 3 corresponding to the cornea side) with respect to the optical part 12 in the initial state shown in FIG. Since the contact reaction force against the sac 24 is exerted in a direction substantially perpendicular to the optical axis of the optical part 12, the support parts 14 and 14 are inclined in a direction in which the inclination angle is further increased with respect to the optical part 12. A bending moment is generated and deformed. That is, by this bending moment, compressive stress is generated on each support portion 14 on the front surface 26 side, while tensile stress is generated on the rear surface 22.

  In particular, the circumferential grooves 28, 30, and 32 are formed on the front surface of each support portion 14, so that even if an axial force is applied in the extending direction of the support portion 14, each circumferential groove 28. , 30, and 32, bending moment is generated by the action of a force that is substantially biased. Therefore, stress concentration is particularly generated at the portions where these circumferential grooves 28, 30, and 32 are formed, and bending deformation in a form that becomes concave on the front surface 26 side and convex on the rear surface 22 side is caused.

  As a result, as shown in an image-like cross-sectional view in FIG. 3, the softness of the support portion 14 itself and the softness of the sac 24 itself are combined, so that the support portions 14 and 14 are extended. Adhering not only to the distal end portion in the outgoing direction but also to a predetermined length region from the distal end edge portion toward the optical portion 12, and further to substantially the entire length as shown in FIG. It will be made to contact | abut in a state.

  In particular, with the increase in the angle of inclination of the support portions 14 and 14 and the deformation of the support portions 14 and 14 in the vicinity of the tip edges of the pair of support portions 14 and 14 where the contact reaction force of the sac 24 is most effectively applied. The force that displaces the optical part 12 toward the rear (the retina side corresponding to the left side in FIG. 3) within the sac 24 is exerted via the support parts 14 and 14.

  As a result, the intraocular lens 10 is positioned in the sac 24 by a locking action or a frictional action associated with the pressing of the support portions 14 and 14 against the inner surface of the sac 24. Moreover, the optical part 12 is pressed against the inner surface of the sac 24 at the outer peripheral edge part and is brought into close contact therewith. In particular, in this embodiment, since the base end side circumferential groove 28 is formed over the entire length of the boundary portion between the optical portion 12 and the support portions 14, 14, the base portion side circumferential groove 28 is bent so as to be broken at the boundary portion. As a result, the outer peripheral edge portion of the optical unit 12 can be pressed in a more advantageous contact state with respect to the inner surface of the sac 24 over the entire circumference, that is, without being disturbed by the support portions 14 and 14.

  Further, the peripheral grooves 28, 30, 32 formed in the support portions 14, 14 are appropriately designed in shape and expansion dimensions, so that the intraocular lens 10 is accommodated in the sac 24. Under the condition, when bent by an external force exerted as a reaction force against the sac 24 of the support portions 14 and 14, as shown in FIGS. The wall surfaces 46 and 48 are in contact with each other. In the circumferential groove 34 having a rectangular cross section as shown in FIG. 4, both side wall surfaces 46 and 48 abut near the opening end of the circumferential groove 34, so that the abutting state can be clearly recognized. Further, in the circumferential grooves 40 and 42 having the inwardly convex curved side walls as shown in FIG. 7 and FIG. 8, the deepest portions of the side wall surfaces 46 and 48 are brought into contact immediately by the slight curvature of the support portion 14. The contact state can be easily recognized. Furthermore, in the circumferential grooves 36 and 38 having a triangular cross section as shown in FIGS. 5 and 6, it is difficult to understand in the drawings, but at the bottom of the circumferential grooves 36 and 38 that become the compression side when the support portion 14 is curved, Since the bottoms of the side wall surfaces 46 and 48, which are a part of the support portion 14 formed of a soft and hardly shrinkable material, bulge into the circumferential grooves 36 and 38 due to compressive stress, the contact state is Easy to understand.

  That is, when the circumferential grooves 28, 30, 32 are formed in the support portion 14 in this manner, the inner wall surfaces 46, 48 of the circumferential grooves 28, 30, 32 are brought into contact with each other when being bent and deformed. At the site where the circumferential grooves 28, 30, and 32 are formed, a large resistance is exerted against further bending deformation. Therefore, the support portion 14 is stably set in the curved position, direction, and shape under the implanted state by the circumferential grooves 28, 30, and 32, and is prevented from irregular deformation. The shape will be stably expressed.

  Moreover, in the formation part where the circumferential grooves 28, 30, and 32 are bent until the both wall inner surfaces 46 and 48 are in contact with each other, the support part 14 passes through the support part 14 to the sac 24 at the distal end portion. The contact reaction force is efficiently transmitted to the optical unit 12. Therefore, the contact reaction force of the support portion 14 with respect to the sac 24 is effectively absorbed and reduced by the deformation at the formation site of each circumferential groove 28, 30, 32, and is caused by excessive transmission of external force to the optical portion 12. Generation of distortion in the optical unit 12 is suppressed. At the same time, the outer peripheral edge of the optical part 12 is pressed against the inner surface of the sac 24 by the contact force of the support part 14 against the sac 24 being effectively exerted on the optical part 12 with an appropriate magnitude. Thus, the effect of preventing secondary cataract can be advantageously exhibited.

  In particular, in the present embodiment, the circumferential grooves in the support portions 14 and 14 have an arc shape extending in the circumferential direction around the substantially central axis of the optical portion 12, and the support portions 14 and 14 are outside the optical portion 12. Since it is connected with a sufficient length with respect to the peripheral portion, the external force exerted through the support portions 14 and 14 is substantially equal to a very wide region over substantially the entire periphery of the outer peripheral portion of the optical portion 12. To act on. Therefore, local stress concentration or the like in the optical unit 12 is more effectively avoided, and the stability of the shape of the optical unit 12 under the implanted state and the stability of the contact state with the sac 24 are both It can be achieved more effectively.

  As mentioned above, although the intraocular lens 10 of one Embodiment of this invention shown by FIGS. 1-3 was explained in full detail, this invention is limitedly interpreted by the specific description about the above-mentioned intraocular lens 10. FIG. It is not something. In order that the present invention may be more accurately understood, several further specific embodiments of the present invention are illustrated and illustrated below. In the following embodiments, members and parts having the same structure as the intraocular lens 10 as the first embodiment described above are denoted by the same reference numerals as those in the first embodiment. Thus, detailed description thereof is omitted.

  FIG. 10 shows a front view of an intraocular lens 50 as a second embodiment of the present invention. In the present embodiment, a substantially oval-shaped light extraction window 52 is formed penetrating in the thickness direction with respect to a substantially central portion of both support portions 14, 14.

  By forming such a light extraction window 52, the length of the connection portion of the support portion 14 with respect to the optical portion 12 and the length of the contact portion with respect to the sac are sufficiently ensured, and the volume of the support portion 14 is reduced. It becomes possible. Thereby, it becomes possible to fold the intraocular lens 50 including the support part 14 smaller. Further, the rigidity and the like of the support portion 14 can be adjusted by appropriately adjusting the shape of the light extraction window 52. Further, it is possible to promote the circulation of body fluid in the sac through the meat extraction window 52. Furthermore, after the intraocular lens 50 is inserted into the sac, when the position of the intraocular lens is adjusted in the sac using an appropriate instrument, the instrument is hooked on the meat extraction window 52, etc. The operation of the lens 50 is facilitated.

  FIG. 11 shows a front view of an intraocular lens 54 as a third embodiment of the present invention. In the present embodiment, a notch 56 is formed for each of the support portions 14 and 14. The notch 56 is formed with an arcuate curved inner surface in such a form that the support parts 14 and 14 are removed from the same circumferential direction around the central axis of the optical part 12. Further, by forming the notch portion 56, each support portion 14 has the narrowest width at the intermediate portion in the extending direction from the optical portion 12.

  By forming such a cutout portion 56, it is possible to effectively obtain the same functions and effects as those of the light extraction window 52 of the intraocular lens 50 in the second embodiment described above.

  FIG. 12 shows a front view of an intraocular lens 58 as a fourth embodiment of the present invention. The intraocular lens 58 of the present embodiment includes an annular support portion 60 that extends over the entire circumference of the outer peripheral edge portion of the optical unit 12 as a support portion. The annular support portion 60 has an annular plate shape, and extends outward in the radial direction with a substantially constant extension dimension over the entire circumference of the optical portion 12.

  In the intraocular lens 58 provided with such an annular support portion 60, the whole including the optical portion 12 and the annular support portion 60 has a rotating body shape having no direction around the central axis. When the lens 58 is folded or rolled up to be small, or inserted into the sac, there is no need to consider its directionality. Therefore, there is an advantage that handling becomes easy. Further, since the outer peripheral edge of the annular support 60 is brought into contact with the inner surface of the sac at a longer part, the optical unit 12 can be positioned in the sac more accurately and stably. Become.

  Each of the intraocular lenses 50, 54, and 58 shown in FIGS. 10 to 12 is substantially the same as the intraocular lens 10 of the first embodiment. Illustration and description are omitted.

  Furthermore, in the intraocular lenses 10, 50, 54, and 58 as the first to fourth embodiments described above, the three circumferential grooves on the base end side, the intermediate side, and the front end side with respect to the support portions 14 and 60 are all provided. Although 28, 30, and 32 are formed, the position and number of the circumferential grooves are not limited at all. Specifically, for example, as shown in FIGS. 13 to 15, as shown in FIGS. 16 to 18, a mode in which each support portion 14 includes two circumferential grooves 30 and 32, and FIGS. Each support portion 14 is provided with one circumferential groove 30, or as shown in FIGS. 19 to 21, each support portion 14 is provided with four circumferential grooves 28, 30, 32, 62. Any aspect can be adopted.

  15, 18, and 21 are model views for explaining the implantation state of the intraocular lens provided with the circumferential groove of each aspect shown in FIGS. 13, 16, and 19 in the sac. Although it is a longitudinal cross-sectional explanatory drawing, illustration of a sac is abbreviate | omitted in those figures. Further, FIGS. 15, 18, and 21 and FIGS. 14, 17, and 20 showing longitudinal sectional views of the respective intraocular lenses are diagrams corresponding to those in the first embodiment for reasons of drawing. It should be noted that the positions of the cornea side and the retina side are opposite to each other on the drawing as compared to FIGS.

  Further, when providing a single circumferential groove, unlike the one shown in FIG. 16, only the proximal circumferential groove 28 in the intraocular lens 10 of the first embodiment is adopted, or the distal side It is also possible to employ only the circumferential groove 32. When providing two circumferential grooves, unlike the one shown in FIG. 14, only the proximal circumferential groove 28 and the intermediate circumferential groove 30 in the intraocular lens 10 of the first embodiment are employed. Alternatively, it is possible to employ only the proximal end side circumferential groove 28 and the distal end side circumferential groove 32. Furthermore, when four or more circumferential grooves are provided, they can be formed at arbitrary intervals in addition to being formed at equal intervals in the extending direction of the support portion.

  FIG. 22 shows an intraocular lens 64 as an eighth embodiment of the present invention. In addition, since the front view of the intraocular lens 64 of this embodiment is substantially the same as FIG. 1, illustration is abbreviate | omitted.

  That is, in the intraocular lens 64 of this embodiment, the thickness dimension t ′ of the support portion 66 is made larger than the thickness dimension of the outer peripheral edge portion of the optical portion 68, and the thickness of the support portion 66 is increased. Thickness dimension: t ′ is set to be equal to or less than the maximum thickness dimension of the optical unit 68. In particular, in the present embodiment, the support portion 66 has a substantially constant thickness except for the portions where the circumferential grooves 28, 30, 32 are formed, and the portions where the circumferential grooves 28, 30, 32 are formed are optically It is set to have a thickness: t ″ smaller than the thickness of the outer peripheral edge of the portion 68. The optical portion 68 has a convex lens shape in which at least one is a convex spherical surface, and has a maximum thickness on the central axis of the optical portion 68 and a minimum thickness on the outer peripheral edge thereof. It has become.

  In such an intraocular lens 64, the maximum thickness dimension of the optical part 68 can be suppressed while ensuring the rigidity of the support part 66 sufficient to prevent irregular deformation due to the action of external force. It becomes possible to fold and wind up compactly. Further, by forming the circumferential grooves 28, 30, 32 having a thickness t ″ smaller than the minimum thickness of the optical portion 68 in the support portion 66, the transmission of stress from the support portion to the optical portion is suppressed. Thus, the deformation of the optical unit 68 under the implanted state can be suppressed.

  In addition, it is desirable for the circumferential groove in the support portion to be continuous over the entire circumferential direction of the support portion for stable deformation in the support portion, but this is not necessarily essential in the present invention. For example, it is also possible to employ a circumferential groove that is divided into broken lines or a circumferential groove that is formed only in a part of the support portion in the width direction.

  Moreover, the support part does not need to contact the inner surface of a sac substantially the whole rear surface. For example, it may be configured to be implanted with only the distal end portion of the support portion in contact with the inner surface of the sac.

  Further, a plurality of support portions may be formed in a number of three or more. In the case where a plurality of support portions are employed, it is desirable that they are substantially equally spaced in the circumferential direction around the central axis of the optical portion 12.

  In addition, although not enumerated one by one, the present invention can be carried out in an embodiment to which various changes, modifications, improvements, etc. are added based on the knowledge of those skilled in the art. It goes without saying that all are included in the present invention without departing from the spirit of the invention.

It is a front view of the intraocular lens as 1st embodiment of this invention. It is a longitudinal cross-sectional view of the intraocular lens shown by FIG. FIG. 2 is a longitudinal explanatory view showing an implanted state of the intraocular lens shown in FIG. 1. It is a longitudinal cross-sectional view which shows the specific example of the circumferential groove | channel which can be employ | adopted in the support part of the intraocular lens shown by FIG. 1, (a) is an enlarged view of (alpha) part in FIG. 2, (b) is the said It is explanatory drawing which shows the deformation | transformation state at the time of the implantation of a part. It is a longitudinal cross-sectional view which shows another specific example of the circumferential groove which can be employ | adopted in the support part of the intraocular lens shown by FIG. 1, Comprising: (a) is an enlarged view of (alpha) part in FIG. These are explanatory drawings which show the deformation | transformation state at the time of the implantation of the said part. It is a longitudinal cross-sectional view which shows another specific example of the circumferential groove which can be employ | adopted in the support part of the intraocular lens shown by FIG. 1, Comprising: (a) is an enlarged view of (alpha) part in FIG. () Is explanatory drawing which shows the deformation | transformation state at the time of the implantation of the said part. It is a longitudinal cross-sectional view which shows another specific example of the circumferential groove which can be employ | adopted in the support part of the intraocular lens shown by FIG. 1, Comprising: (a) is an enlarged view of (alpha) part in FIG. () Is explanatory drawing which shows the deformation | transformation state at the time of the implantation of the said part. It is a longitudinal cross-sectional view which shows another specific example of the circumferential groove which can be employ | adopted in the support part of the intraocular lens shown by FIG. 1, Comprising: (a) is an enlarged view of (alpha) part in FIG. () Is explanatory drawing which shows the deformation | transformation state at the time of the implantation of the said part. It is explanatory drawing which illustrates the insertion means in the eye of the intraocular lens shown by FIG. It is a front view of the intraocular lens as 2nd embodiment of this invention. It is a front view of the intraocular lens as 3rd embodiment of this invention. It is a front view of the intraocular lens as 4th embodiment of this invention. It is a front view of the intraocular lens as 5th embodiment of this invention. It is a longitudinal cross-sectional view of the intraocular lens shown by FIG. It is longitudinal cross-sectional explanatory drawing which shows the implantation state of the intraocular lens shown by FIG. It is a front view of the intraocular lens as 6th embodiment of this invention. It is a longitudinal cross-sectional view of the intraocular lens shown by FIG. FIG. 17 is a longitudinal cross-sectional explanatory view showing an implanted state of the intraocular lens shown in FIG. 16. It is a front view of the intraocular lens as 7th embodiment of this invention. It is a longitudinal cross-sectional view of the intraocular lens shown by FIG. FIG. 20 is a longitudinal cross-sectional explanatory view showing an implanted state of the intraocular lens shown in FIG. 19. It is a longitudinal cross-sectional view of the intraocular lens as 8th embodiment of this invention.

Explanation of symbols

10 Intraocular lens (first embodiment)
12 Optical part 14 Support part 16 Front face (of optical part) 18 Rear face of (optical part) 22 Rear face of (support part) 24 Sac 26 Front face of (support part) 28 Proximal peripheral groove 30 Intermediate peripheral groove 32 Front peripheral part Groove 50 Intraocular lens (second embodiment)
54 Intraocular lens (third embodiment)
58 Intraocular lens (fourth embodiment)
64 Intraocular lens (eighth embodiment)

Claims (21)

An optical part configured to include a lens region having predetermined optical characteristics and having a substantially circular shape when viewed from the front, and an outer peripheral part of the sac extending from the optical part toward the outer peripheral side and inserted into the eye And a support portion that positions and holds the optical portion by pressing the optical portion against the inner surface of the retinal side of the sac by being brought into contact with the inner surface of the sac, and is integrally formed of a soft material that can be folded or rolled up. In one-piece type intraocular lenses,
A circumferential groove extending in the circumferential direction of the optical unit is formed on the front surface of the support unit positioned on the cornea side in the intraocular insertion state, and the distal end portion of the support unit is located on the outer periphery of the capsule under the intraocular insertion state. The support portion is bent at the formation portion of the circumferential groove by utilizing an external force exerted by being brought into contact with the inner surface of the portion, and the circumferential groove is deformed so that the circumferential groove is crushed in the groove width direction. A one-piece type intraocular lens, characterized in that the inner surfaces of both walls in the width direction are in contact with each other.   The support portion has a substantially constant thickness dimension over the entire surface, and the circumferential groove is formed so as to open to the front surface thereof, so that the thickness dimension of the circumferential groove forming portion is the support size. The one-piece type intraocular lens according to claim 1, wherein the one-piece type intraocular lens is smaller than the other part of the part.   The tip portion of at least the peripheral groove forming portion of the support portion is inclined toward the front side in the optical axis direction of the optical portion, and extends from the optical portion to the outer peripheral side. A one-piece intraocular lens as described in 1.   4. The rear surface of the support portion positioned on the retina side in an intraocular insertion state is a continuous surface made of a smooth flat surface or a curved surface with no broken lines or local unevenness over the entire rear surface. A one-piece intraocular lens according to any one of the above.   The front surface of the support portion is a continuous surface made of a smooth flat surface or a curved surface having no broken line or local unevenness over substantially the entire area excluding the portion where the circumferential groove is formed. A one-piece intraocular lens according to the above.   The one-piece type intraocular lens according to any one of claims 1 to 5, wherein the circumferential groove in the support part is formed on a substantially boundary line between the support part and the optical part.   The thickness dimension of the end part on the support part side is larger than the thickness dimension on the end part on the optical part side, with the circumferential groove formed on the boundary line between the support part and the optical part interposed therebetween. Item 7. A one-piece intraocular lens according to item 6.   The optical part positioned on the retina side in an intraocular insertion state at the boundary portion between the optical part and the support part and both rear surfaces of the support part are connected by a smooth surface having a common tangent line. A one-piece intraocular lens according to any one of 1 to 7.   The one-piece type intraocular according to any one of claims 1 to 8, wherein the circumferential groove in the support part is a circular or arcuate groove extending in the circumferential direction on substantially the same central axis as the optical part. lens.   The one-piece intraocular lens according to any one of claims 1 to 9, wherein the circumferential groove in the support portion extends in the circumferential direction with a cross-sectional shape that gradually expands from the bottom toward the opening.   The value of the ratio of the projection area: b in the optical axis direction of the support part to the projection area: a in the optical axis direction of the optical part is set to b / a = 0.3 to 3.0. The one-piece type intraocular lens according to any one of 1 to 10.   The value of the ratio of the thickness dimension: t (min) at the portion where the circumferential groove is formed in the support portion to the maximum thickness dimension: t (max) in the support portion is t (min) / t (max) = The one-piece intraocular lens according to any one of claims 1 to 11, wherein the intraocular lens is 0.5 to 0.8.   The one-piece type intraocular lens according to any one of claims 1 to 12, wherein a thickness dimension of the support portion is 0.1 to 0.55 mm.   The one-piece type intraocular lens according to any one of claims 1 to 13, wherein an outer diameter of the optical unit is 3.2 to 6.0 mm.   The one-piece type intraocular lens according to claim 1, wherein a maximum thickness of the optical part is 0.1 to 0.75 mm.   The support portions are formed so as to be opposed to each other on both sides of the central axis of the optical portion, and are formed substantially independently of each other. The one-piece type intraocular lens according to claim 1, wherein the one-piece intraocular lens is formed.   The one-piece type intraocular lens according to any one of claims 1 to 16, wherein a plurality of the circumferential grooves are formed apart from each other in the extending direction of the support portion.   Under the intraocular insertion state, the support portion is bent at each forming portion of the circumferential groove formed with a plurality of strips, so that the rear surface of the support portion is in a region of a predetermined length from the tip portion toward the optical portion. The one-piece type intraocular lens according to claim 17, wherein the one-piece type intraocular lens is superposed on and in contact with the inner surface of the sac. A plurality of the circumferential grooves,
A proximal-side circumferential groove located on the optical part side from the center in the extending direction of the support part;
A tip side circumferential groove located on the tip side from the center in the extending direction of the support;
The one-piece intraocular lens according to claim 17 or 18, comprising at least one intermediate circumferential groove positioned between the proximal end side circumferential groove and the distal end side circumferential groove.   The one-piece intraocular lens according to any one of claims 1 to 19, wherein the soft material has a glass transition temperature of 30 ° C or lower and a refractive index of 1.51 or higher. A positioning structure for a one-piece intraocular lens according to any one of claims 1 to 20,
Using the external force exerted by bringing the tip of the support portion into contact with the inner surface of the outer peripheral portion of the sac under insertion into the eye, the support portion is bent and deformed at the peripheral groove forming portion, and The groove is deformed so as to be crushed in the groove width direction, and the inner surfaces of both walls in the groove width direction of the circumferential groove are brought into contact with each other, so that it is exerted on the support portion through the contact portion of the inner surfaces of both walls of the circumferential groove. A one-piece type intraocular lens characterized in that an external force is transmitted in the extending direction of the support part to act on the optical part, thereby positioning the optical part against the inner surface of the sac on the retina side. Positioning structure.

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