JP2005510462A - 免疫調節オリゴヌクレオチドの生成及びその使用方法 - Google Patents
免疫調節オリゴヌクレオチドの生成及びその使用方法 Download PDFInfo
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- JP2005510462A JP2005510462A JP2003520774A JP2003520774A JP2005510462A JP 2005510462 A JP2005510462 A JP 2005510462A JP 2003520774 A JP2003520774 A JP 2003520774A JP 2003520774 A JP2003520774 A JP 2003520774A JP 2005510462 A JP2005510462 A JP 2005510462A
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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- A—HUMAN NECESSITIES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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- A—HUMAN NECESSITIES
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- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/17—Immunomodulatory nucleic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/315—Phosphorothioates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
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- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
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- Plant Pathology (AREA)
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- Biochemistry (AREA)
- Pulmonology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/927,422 US7250403B2 (en) | 2000-03-10 | 2001-08-10 | Biodegradable immunomodulatory formulations and methods for use thereof |
| US09/927,884 US7183111B2 (en) | 2000-03-10 | 2001-08-10 | Immunomodulatory formulations and methods for use thereof |
| PCT/US2001/025364 WO2003015816A1 (en) | 2001-08-10 | 2001-08-13 | Immunomodulatory oligonucleotide formulations and methods for use thereof |
Publications (2)
| Publication Number | Publication Date |
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| JP2005510462A true JP2005510462A (ja) | 2005-04-21 |
| JP2005510462A5 JP2005510462A5 (enrdf_load_stackoverflow) | 2008-10-02 |
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| JP2003520774A Pending JP2005510462A (ja) | 2001-08-10 | 2001-08-13 | 免疫調節オリゴヌクレオチドの生成及びその使用方法 |
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| Country | Link |
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| EP (1) | EP1414490A1 (enrdf_load_stackoverflow) |
| JP (1) | JP2005510462A (enrdf_load_stackoverflow) |
| AU (1) | AU2001281267B2 (enrdf_load_stackoverflow) |
| CA (1) | CA2456201A1 (enrdf_load_stackoverflow) |
| WO (1) | WO2003015816A1 (enrdf_load_stackoverflow) |
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| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US20030129251A1 (en) | 2000-03-10 | 2003-07-10 | Gary Van Nest | Biodegradable immunomodulatory formulations and methods for use thereof |
| US7129222B2 (en) | 2000-03-10 | 2006-10-31 | Dynavax Technologies Corporation | Immunomodulatory formulations and methods for use thereof |
| WO2002052002A2 (en) | 2000-12-27 | 2002-07-04 | Dynavax Technologies Corporation | Immunomodulatory polynucleotides and methods of using the same |
| US8158768B2 (en) | 2002-12-23 | 2012-04-17 | Dynavax Technologies Corporation | Immunostimulatory sequence oligonucleotides and methods of using the same |
| AU2005230938A1 (en) * | 2004-02-19 | 2005-10-20 | Coley Pharmaceutical Gmbh | Immunostimulatory viral RNA oligonucleotides |
| WO2010142660A2 (en) * | 2009-06-09 | 2010-12-16 | Novartis Ag | Drug delivery system |
| US10894963B2 (en) | 2013-07-25 | 2021-01-19 | Exicure, Inc. | Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999062923A2 (en) * | 1998-06-05 | 1999-12-09 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides with modified bases and methods of use thereof |
| JP2003526682A (ja) * | 2000-03-10 | 2003-09-09 | ダイナバックス テクノロジーズ コーポレイション | 生物分解性免疫調節製剤及びその使用方法 |
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| WO1998052581A1 (en) * | 1997-05-20 | 1998-11-26 | Ottawa Civic Hospital Loeb Research Institute | Vectors and methods for immunization or therapeutic protocols |
| EP1117433A1 (en) * | 1998-10-09 | 2001-07-25 | Dynavax Technologies Corporation | Anti hiv compositions comprising immunostimulatory polynucleotides and hiv antigens |
| GB9915204D0 (en) * | 1999-06-29 | 1999-09-01 | Smithkline Beecham Biolog | Vaccine |
| MXPA02002107A (es) * | 1999-08-27 | 2003-08-20 | Inex Pharmaceuticals Corp | Composiciones para estimular la secrecion de citoquina e inducir una respuesta inmune. |
| US20020107212A1 (en) * | 2000-03-10 | 2002-08-08 | Nest Gary Van | Methods of reducing papillomavirus infection using immunomodulatory polynucleotide sequences |
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2001
- 2001-08-13 EP EP01959743A patent/EP1414490A1/en not_active Ceased
- 2001-08-13 CA CA002456201A patent/CA2456201A1/en not_active Abandoned
- 2001-08-13 AU AU2001281267A patent/AU2001281267B2/en not_active Ceased
- 2001-08-13 WO PCT/US2001/025364 patent/WO2003015816A1/en active Application Filing
- 2001-08-13 JP JP2003520774A patent/JP2005510462A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999062923A2 (en) * | 1998-06-05 | 1999-12-09 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides with modified bases and methods of use thereof |
| JP2003526682A (ja) * | 2000-03-10 | 2003-09-09 | ダイナバックス テクノロジーズ コーポレイション | 生物分解性免疫調節製剤及びその使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001281267B2 (en) | 2008-05-15 |
| WO2003015816A1 (en) | 2003-02-27 |
| EP1414490A1 (en) | 2004-05-06 |
| CA2456201A1 (en) | 2003-02-27 |
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