JP2005091241A5 - - Google Patents
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- JP2005091241A5 JP2005091241A5 JP2003327035A JP2003327035A JP2005091241A5 JP 2005091241 A5 JP2005091241 A5 JP 2005091241A5 JP 2003327035 A JP2003327035 A JP 2003327035A JP 2003327035 A JP2003327035 A JP 2003327035A JP 2005091241 A5 JP2005091241 A5 JP 2005091241A5
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［１］ 本発明の磁性粒子は、金属酸化物を炭素で還元することによって得られる平均粒径１μｍ以下の金属粒子と、前記金属粒子を包含若しくは担持する炭素粒子若しくは炭素膜を有し磁気ビーズ用であることを特徴とする。望ましくは前記金属粒子の平均粒径を０．００１〜１μｍとする。 [1] Magnetic particles of the present invention, the average particle size 1μm or less of the metal particles obtained by reducing a metal oxide with carbon, magnetic beads have a carbon particle or carbon film to cover or carrying the metal particles It is for use . Desirably, the average particle diameter of the metal particles is 0.001 to 1 μm.
本発明の磁性粒子は、特に磁気ビーズ用の磁性粒子として用いることができる。ここで、“磁気ビーズ用”とは、生体物質を水溶液中から抽出したり、或いは生体物質を水溶液中に分散させるような用途に相当し、磁気ビーズとして用いることができるという意味である。従って、本願明細書において、“磁気ビーズ用”とは、本発明の磁性粒子の組成等を限定する用語ではない。 The magnetic particles of the present invention can be used particularly as magnetic particles for magnetic beads. Here, “for magnetic beads” means that the biological material is extracted from the aqueous solution or the biological material is dispersed in the aqueous solution and can be used as a magnetic bead. Therefore, in the present specification, “for magnetic beads” is not a term for limiting the composition and the like of the magnetic particles of the present invention.
平均粒径は、例えば、金属超微粒子の試料粉末を溶媒中に分散させて、レーザー光線を照射して回折を利用して平均粒径を測定する方法（第１の方法）により求めることができる。第１の方法では平均粒径の測定が困難な場合には、試料を電子顕微鏡で観察して平均粒径を測定する試料の電子顕微鏡写真を取る。写真内で任意の長さの線分を引いて、線分の粒子を横断する部分の長さの和Ｌと線分が横断した粒子の数Ｎとから、平均粒径＝Ｌ／Ｎとして求める。ただし、測定対象の粒子の数を５０個以上として平均値を求める。 The average particle diameter can be determined, for example, by a method (first method) in which a sample powder of ultrafine metal particles is dispersed in a solvent, irradiated with a laser beam, and the average particle diameter is measured using diffraction. When it is difficult to measure the average particle diameter by the first method, the sample is observed with an electron microscope and an electron micrograph of the sample for measuring the average particle diameter is taken. A line segment of an arbitrary length is drawn in the photograph, and the average particle size = L / N is obtained from the sum L of the lengths of the portions crossing the particles of the line segment and the number N of particles crossed by the line segment. . However, the average value is obtained by setting the number of particles to be measured to 50 or more.
［２］ 本発明の他の磁性粒子は、金属酸化物をホウ素で還元することによって得られる平均粒径１μｍ以下の金属粒子と、前記金属粒子を包含若しくは担持する窒化ホウ素粒子若しくは窒化ホウ素膜を有し磁気ビーズ用であることを特徴とする。望ましくは前記金属粒子の平均粒径を０．００１〜１μｍとする。 [2] Another magnetic particle of the present invention includes a metal particle having an average particle size of 1 μm or less obtained by reducing a metal oxide with boron, and a boron nitride particle or a boron nitride film containing or supporting the metal particle. Yes and characterized in that it is a magnetic bead. Desirably, the average particle diameter of the metal particles is 0.001 to 1 μm.
Claims (5)
γ＞６／（ｒ・ρ） γ> 6 / (r · ρ)
を満足する請求項１または２に記載の磁性粒子。The magnetic particle according to claim 1 or 2, satisfying
前記金属粒子は平均粒径が０．００１〜１μｍであり、 The metal particles have an average particle diameter of 0.001 to 1 μm,
前記被膜は、金、銀もしくは白金族元素の少なくとも一つで構成される貴金属であり、 The coating is a noble metal composed of at least one of gold, silver or platinum group elements,
比表面積をγ（ｍ The specific surface area is γ (m ２2 ／ｇ）、粒度をｒ（μｍ）、密度をρ（ｇ／ｃｍ/ G), particle size r (μm), density ρ (g / cm 3Three ）としたときに、γ＞６／（ｒ・ρ）を満たすことを特徴とする磁性粒子。) Satisfying γ> 6 / (r · ρ).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003327035A JP4164806B2 (en) | 2003-09-19 | 2003-09-19 | Magnetic particles for magnetic beads |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003327035A JP4164806B2 (en) | 2003-09-19 | 2003-09-19 | Magnetic particles for magnetic beads |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008024792A Division JP2008135779A (en) | 2008-02-05 | 2008-02-05 | Method of manufacturing magnetic particles for magnetic bead |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005091241A JP2005091241A (en) | 2005-04-07 |
| JP2005091241A5 true JP2005091241A5 (en) | 2006-05-25 |
| JP4164806B2 JP4164806B2 (en) | 2008-10-15 |
Family
ID=34457016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003327035A Expired - Fee Related JP4164806B2 (en) | 2003-09-19 | 2003-09-19 | Magnetic particles for magnetic beads |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4164806B2 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2006126504A1 (en) * | 2005-05-23 | 2008-12-25 | 独立行政法人産業技術総合研究所 | Silver-coated particles and uses thereof |
| JP4465038B2 (en) * | 2008-08-20 | 2010-05-19 | 株式会社フォスメガ | Magnetic field sensor |
| EP2383374A1 (en) * | 2010-04-29 | 2011-11-02 | BASF Corporation | Nano-particles containing carbon and a ferromagnetic metal or alloy |
| CN102351564B (en) * | 2011-07-20 | 2012-11-21 | 福州大学 | Method for preparing wood ceramics by sintering coal tar pitch and biomass materials |
| JP2012096232A (en) * | 2011-12-26 | 2012-05-24 | Hitachi Maxell Ltd | Method for producing magnetic carrier |
-
2003
- 2003-09-19 JP JP2003327035A patent/JP4164806B2/en not_active Expired - Fee Related
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