JP2004535178A - 新規変異 - Google Patents
新規変異 Download PDFInfo
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- JP2004535178A JP2004535178A JP2002587594A JP2002587594A JP2004535178A JP 2004535178 A JP2004535178 A JP 2004535178A JP 2002587594 A JP2002587594 A JP 2002587594A JP 2002587594 A JP2002587594 A JP 2002587594A JP 2004535178 A JP2004535178 A JP 2004535178A
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- Prior art keywords
- sodium channel
- polypeptide
- epilepsy
- mutation event
- subunit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
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- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPR4922A AUPR492201A0 (en) | 2001-05-10 | 2001-05-10 | Novel mutation |
| PCT/AU2002/000581 WO2002090532A1 (en) | 2001-05-10 | 2002-05-09 | Novel mutation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004535178A true JP2004535178A (ja) | 2004-11-25 |
| JP2004535178A5 JP2004535178A5 (https=) | 2005-08-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002587594A Abandoned JP2004535178A (ja) | 2001-05-10 | 2002-05-09 | 新規変異 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040191791A1 (https=) |
| EP (1) | EP1385945A4 (https=) |
| JP (1) | JP2004535178A (https=) |
| AU (1) | AUPR492201A0 (https=) |
| CA (1) | CA2446838A1 (https=) |
| WO (1) | WO2002090532A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005501536A (ja) | 2001-07-18 | 2005-01-20 | バイオノミックス リミテッド | イオンチャネルにおける変異 |
| WO2008079412A2 (en) * | 2006-12-22 | 2008-07-03 | The Trustees Of Columbia University In The City Of New York | Methods and compositions to treat arrhythmias |
| MX2019011772A (es) | 2017-04-03 | 2020-01-09 | Encoded Therapeutics Inc | Expresion transgenica selectiva de tejidos. |
| EP3717505A4 (en) | 2017-12-01 | 2021-12-01 | Encoded Therapeutics, Inc. | GENENICALLY MODIFIED DNA-BINDING PROTEINS |
| PL3976798T3 (pl) | 2019-05-29 | 2026-04-07 | Encoded Therapeutics, Inc. | Kompozycje i sposoby selektywnej regulacji genów |
| WO2024038160A1 (en) * | 2022-08-18 | 2024-02-22 | Vib Vzw | Means and methods to modulate neuron excitability |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU777469B2 (en) * | 1999-04-15 | 2004-10-21 | Cambridge University Technical Services Limited | A novel family of beta sub-unit proteins from a voltage-gated sodium channel, nucleic acids encoding them and therapeutic or diagnostic uses thereof |
| DE1252330T1 (de) * | 1999-11-26 | 2003-11-27 | Mcgill University, Montreal | Loci der idiopathischen epilepsie, mutationen derselben und verfahren zu deren verwendung zur feststellung, prognose und behandlung von epilepsie |
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2001
- 2001-05-10 AU AUPR4922A patent/AUPR492201A0/en not_active Abandoned
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2002
- 2002-05-09 JP JP2002587594A patent/JP2004535178A/ja not_active Abandoned
- 2002-05-09 WO PCT/AU2002/000581 patent/WO2002090532A1/en not_active Ceased
- 2002-05-09 US US10/477,272 patent/US20040191791A1/en not_active Abandoned
- 2002-05-09 EP EP02721852A patent/EP1385945A4/en not_active Withdrawn
- 2002-05-09 CA CA002446838A patent/CA2446838A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1385945A4 (en) | 2004-12-22 |
| EP1385945A1 (en) | 2004-02-04 |
| AUPR492201A0 (en) | 2001-06-07 |
| CA2446838A1 (en) | 2002-11-14 |
| US20040191791A1 (en) | 2004-09-30 |
| WO2002090532A1 (en) | 2002-11-14 |
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