JP2004529893A5 - - Google Patents
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- Publication number
- JP2004529893A5 JP2004529893A5 JP2002569239A JP2002569239A JP2004529893A5 JP 2004529893 A5 JP2004529893 A5 JP 2004529893A5 JP 2002569239 A JP2002569239 A JP 2002569239A JP 2002569239 A JP2002569239 A JP 2002569239A JP 2004529893 A5 JP2004529893 A5 JP 2004529893A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- eletriptan
- measured
- absence
- oral bioavailability
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003112 inhibitor Substances 0.000 claims 27
- OTLDLQZJRFYOJR-LJQANCHMSA-N eletriptan Chemical compound CN1CCC[C@@H]1CC1=CN=C2[C]1C=C(CCS(=O)(=O)C=1C=CC=CC=1)C=C2 OTLDLQZJRFYOJR-LJQANCHMSA-N 0.000 claims 19
- 229960002472 eletriptan Drugs 0.000 claims 19
- 239000000203 mixture Substances 0.000 claims 14
- 239000003795 chemical substances by application Substances 0.000 claims 10
- 239000003814 drug Substances 0.000 claims 6
- 208000019695 Migraine disease Diseases 0.000 claims 4
- 239000002552 dosage form Substances 0.000 claims 4
- TTWJBBZEZQICBI-UHFFFAOYSA-N metoclopramide Chemical compound CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC TTWJBBZEZQICBI-UHFFFAOYSA-N 0.000 claims 4
- 229960004503 metoclopramide Drugs 0.000 claims 4
- 206010027599 migraine Diseases 0.000 claims 4
- 239000003085 diluting agent Substances 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 claims 2
- 230000035876 healing Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 1
- 229960003276 erythromycin Drugs 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0105131.7A GB0105131D0 (en) | 2001-03-01 | 2001-03-01 | Compositions having improved bioavailability |
| PCT/IB2002/000512 WO2002070070A2 (en) | 2001-03-01 | 2002-02-20 | Compositions having improved bioavailability of eletriptan |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004529893A JP2004529893A (ja) | 2004-09-30 |
| JP2004529893A5 true JP2004529893A5 (enrdf_load_stackoverflow) | 2005-05-26 |
Family
ID=9909814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002569239A Pending JP2004529893A (ja) | 2001-03-01 | 2002-02-20 | 改善されたバイオアベイラビリティーを有する組成物 |
Country Status (8)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004089365A1 (en) * | 2003-04-11 | 2004-10-21 | Pfizer Limited | Pharmaceutical combination comprising eletriptan and sodium bicarbonate |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9709739D0 (en) * | 1997-05-14 | 1997-07-02 | Merck Sharp & Dohme | Pharmaceutical formulation |
| US6255334B1 (en) * | 1998-10-30 | 2001-07-03 | Pfizer Inc | 5HT 1 receptor agonists and metoclopramide for the treatment of migraine |
-
2001
- 2001-03-01 GB GBGB0105131.7A patent/GB0105131D0/en not_active Ceased
-
2002
- 2002-02-20 EP EP02712162A patent/EP1372785A2/en not_active Withdrawn
- 2002-02-20 BR BR0207751-5A patent/BR0207751A/pt not_active IP Right Cessation
- 2002-02-20 AU AU2002232061A patent/AU2002232061A1/en not_active Abandoned
- 2002-02-20 MX MXPA03007836A patent/MXPA03007836A/es unknown
- 2002-02-20 CA CA002439917A patent/CA2439917A1/en not_active Abandoned
- 2002-02-20 JP JP2002569239A patent/JP2004529893A/ja active Pending
- 2002-02-20 WO PCT/IB2002/000512 patent/WO2002070070A2/en not_active Application Discontinuation
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