JP2004525952A - Ｍｒｐ１を阻害するための化合物および医薬組成物 - Google Patents

Ｍｒｐ１を阻害するための化合物および医薬組成物 Download PDF

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Publication number
JP2004525952A
JP2004525952A JP2002579468A JP2002579468A JP2004525952A JP 2004525952 A JP2004525952 A JP 2004525952A JP 2002579468 A JP2002579468 A JP 2002579468A JP 2002579468 A JP2002579468 A JP 2002579468A JP 2004525952 A JP2004525952 A JP 2004525952A
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JP
Japan
Prior art keywords
optionally substituted
alkyl
heterocycle
mmol
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2002579468A
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English (en)
Japanese (ja)
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JP2004525952A5 (OSRAM
Inventor
ジェフリー・ダニエル・コーエン
ルイス・ニコラウス・ジュンガイム
ブライアン・スティーブン・ミュール
ケネス・ジェフ・スラッシャー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
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Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JP2004525952A publication Critical patent/JP2004525952A/ja
Publication of JP2004525952A5 publication Critical patent/JP2004525952A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002579468A 2001-04-09 2002-03-27 Ｍｒｐ１を阻害するための化合物および医薬組成物 Pending JP2004525952A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28264201P 2001-04-09 2001-04-09
PCT/US2002/006662 WO2002081480A1 (en) 2001-04-09 2002-03-27 Compounds and pharmaceutical compositions for inhibiting mrp1

Publications (2)

Publication Number Publication Date
JP2004525952A true JP2004525952A (ja) 2004-08-26
JP2004525952A5 JP2004525952A5 (OSRAM) 2005-12-22

Family

ID=23082449

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002579468A Pending JP2004525952A (ja) 2001-04-09 2002-03-27 Ｍｒｐ１を阻害するための化合物および医薬組成物

Country Status (5)

Country Link
US (1) US7101891B2 (OSRAM)
EP (1) EP1392701A1 (OSRAM)
JP (1) JP2004525952A (OSRAM)
CA (1) CA2442141A1 (OSRAM)
WO (1) WO2002081480A1 (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
EP1931652A2 (en) * 2005-09-21 2008-06-18 Incyte Corporation Amido compounds and their use as pharmaceuticals
US20070213311A1 (en) * 2006-03-02 2007-09-13 Yun-Long Li Modulators of 11-beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID27364A (id) 1998-04-08 2001-04-05 Lilly Co Eli Metode untuk menghambat mrp1
US6743794B2 (en) * 1999-12-22 2004-06-01 Eli Lilly And Company Methods and compounds for inhibiting MRP1

Also Published As

Publication number Publication date
CA2442141A1 (en) 2002-10-17
EP1392701A1 (en) 2004-03-03
US7101891B2 (en) 2006-09-05
WO2002081480A1 (en) 2002-10-17
US20040116460A1 (en) 2004-06-17

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