JP2004511237A5 - - Google Patents

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Publication number
JP2004511237A5
JP2004511237A5 JP2002534565A JP2002534565A JP2004511237A5 JP 2004511237 A5 JP2004511237 A5 JP 2004511237A5 JP 2002534565 A JP2002534565 A JP 2002534565A JP 2002534565 A JP2002534565 A JP 2002534565A JP 2004511237 A5 JP2004511237 A5 JP 2004511237A5
Authority
JP
Japan
Prior art keywords
reagent
test
screened
molecules
molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002534565A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004511237A (ja
Filing date
Publication date
Priority claimed from US09/687,593 external-priority patent/US6787321B1/en
Application filed filed Critical
Publication of JP2004511237A publication Critical patent/JP2004511237A/ja
Publication of JP2004511237A5 publication Critical patent/JP2004511237A5/ja
Pending legal-status Critical Current

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JP2002534565A 2000-10-13 2001-10-09 代謝生成物の蓄積のモジュレーターについてスクリーニングするための哺乳動物2−ハイブリッドシステム Pending JP2004511237A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/687,593 US6787321B1 (en) 2000-10-13 2000-10-13 Mammalian two-hybrid system for screening for modulators of the accumulation of metabolic products
PCT/US2001/031745 WO2002031201A2 (en) 2000-10-13 2001-10-09 Mammalian two-hybrid system for screening for modulators of the accumulation of metabolic products

Publications (2)

Publication Number Publication Date
JP2004511237A JP2004511237A (ja) 2004-04-15
JP2004511237A5 true JP2004511237A5 (OSRAM) 2009-01-29

Family

ID=24761035

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002534565A Pending JP2004511237A (ja) 2000-10-13 2001-10-09 代謝生成物の蓄積のモジュレーターについてスクリーニングするための哺乳動物2−ハイブリッドシステム

Country Status (7)

Country Link
US (2) US6787321B1 (OSRAM)
EP (1) EP1327003B1 (OSRAM)
JP (1) JP2004511237A (OSRAM)
AT (1) ATE520788T1 (OSRAM)
AU (1) AU2001296805A1 (OSRAM)
CA (1) CA2424317A1 (OSRAM)
WO (1) WO2002031201A2 (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2510179C (en) * 2002-12-18 2013-04-23 Chromagenics B.V. A method for improving protein production
MX2007014221A (es) * 2005-05-19 2009-02-17 Wyeth Corp Metodo para identificar compuestos que modulan la interaccion del receptor de androgeno con beta-catenina.
WO2008106087A1 (en) * 2007-02-28 2008-09-04 The Brigham And Women's Hospital, Inc. Compositions and methods for identifying factors affecting protein stability
EP2500428A3 (en) 2007-07-11 2012-12-26 Yeda Research and Development Co. Ltd. Nucleic acid construct systems capable of diagnosing or treating a cell state
WO2011019763A2 (en) * 2009-08-10 2011-02-17 The Board Of Trustees Of The University Of Illinois Compositions and methods for the treatment of krabbe and other neurodegenerative diseases
WO2019099678A1 (en) 2017-11-16 2019-05-23 Synthex, Inc. Selective modulation of protein-protein interactions
WO2020232343A1 (en) * 2019-05-15 2020-11-19 Synthex, Inc. Selective degradation of proteins

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0370813A3 (en) 1988-11-25 1991-06-19 Exemplar Corporation Rapid screening mutagenesis and teratogenesis assay
US5283173A (en) 1990-01-24 1994-02-01 The Research Foundation Of State University Of New York System to detect protein-protein interactions
US5525490A (en) 1994-03-29 1996-06-11 Onyx Pharmaceuticals, Inc. Reverse two-hybrid method
NZ502795A (en) 1995-04-11 2001-09-28 Gen Hospital Corp Method of identifying molecular interactions employing counterselection and at least two hybrid molecules or two hybrid systems
FR2734567B1 (fr) 1995-05-26 1997-08-08 Commissariat Energie Atomique Proteines chimeriques activant la transcription par la polymerase iii, leur utilisation pour la detection et l'analyse des interactions entre proteines, et genes codant pour lesdites proteines
USH1892H (en) 1995-07-27 2000-10-03 Pharmacia And Upjohn Company High volume nutrient based yeast two-hybrid assay for the identification of specific protein:protein interacting inhibitors
US5948620A (en) 1996-08-05 1999-09-07 Amersham International Plc Reverse two-hybrid system employing post-translation signal modulation
US6133027A (en) 1996-08-07 2000-10-17 City Of Hope Inducible expression system
AU721549B2 (en) 1996-12-11 2000-07-06 Bristol-Myers Squibb Company Prokaryotic two-hybrid system
US5851775A (en) * 1997-03-20 1998-12-22 Johns Hopkins University β-catenin, Tcf-4, and APC interact to prevent cancer
US5885779A (en) * 1997-09-09 1999-03-23 University Of British Columbia Repressed trans-activator system for characterization of protein-protein interactions
US6242253B1 (en) * 1997-10-09 2001-06-05 Regents Of The University Of California IkB kinase, subunits thereof, and methods of using same

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