JP2004508006A5 - - Google Patents
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- Publication number
- JP2004508006A5 JP2004508006A5 JP2001558068A JP2001558068A JP2004508006A5 JP 2004508006 A5 JP2004508006 A5 JP 2004508006A5 JP 2001558068 A JP2001558068 A JP 2001558068A JP 2001558068 A JP2001558068 A JP 2001558068A JP 2004508006 A5 JP2004508006 A5 JP 2004508006A5
- Authority
- JP
- Japan
- Prior art keywords
- angiogenic disease
- plasminogen
- plasmin
- animal
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002491 angiogenic Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 229940012957 Plasmin Drugs 0.000 description 1
- 102000013566 Plasminogen Human genes 0.000 description 1
- 108010051456 Plasminogen Proteins 0.000 description 1
- 102000001938 Plasminogen Activators Human genes 0.000 description 1
- 108010001014 Plasminogen Activators Proteins 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000000896 plasminic Effects 0.000 description 1
Description
【特許請求の範囲】
【請求項１】 血管新生疾患の動物に、プラスミノーゲンのプラスミンへの変換を起こさせるのに有効な量のプラスミノーゲンアクチベーターを投与することを含んでなる、血管新生疾患の治療方法。
[Claims]
1. A method for treating an angiogenic disease, which comprises administering to an animal having an angiogenic disease an amount of plasminogen activator effective to cause conversion of plasminogen to plasmin.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50039700A | 2000-02-08 | 2000-02-08 | |
| PCT/US2001/004021 WO2001058921A2 (en) | 2000-02-08 | 2001-02-08 | Methods and compositions for generating angiostatin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004508006A JP2004508006A (en) | 2004-03-18 |
| JP2004508006A5 true JP2004508006A5 (en) | 2008-04-03 |
Family
ID=23989238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001558068A Pending JP2004508006A (en) | 2000-02-08 | 2001-02-08 | Methods and compositions for producing angiostatin |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1263452A4 (en) |
| JP (1) | JP2004508006A (en) |
| AU (1) | AU2001234926A1 (en) |
| CA (1) | CA2400497A1 (en) |
| WO (1) | WO2001058921A2 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2451835A1 (en) * | 2009-07-10 | 2012-05-16 | ThromboGenics N.V. | Variants of plasminogen and plasmin |
| CN103384722B (en) | 2011-01-05 | 2016-11-16 | 斯路姆基因公司 | Plasminogen and fibrinolysin variant |
| KR20140064841A (en) | 2011-08-12 | 2014-05-28 | 쓰롬보제닉스 엔.브이. | Plasminogen and plasmin variants |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8272887A (en) * | 1986-10-31 | 1988-05-25 | David F. Carmichael | Method for inducing endogenous production of tissue plasminogen activator (tpa) |
| NZ230808A (en) * | 1988-10-24 | 1993-04-28 | Squibb & Sons Inc | Pharmaceutical compositions and combinations containing an angiotensin-converting enzyme inhibitor and a thrombolytic agent |
| US5801012A (en) * | 1996-09-17 | 1998-09-01 | Northwestern University | Methods and compositions for generating angiostatin |
-
2001
- 2001-02-08 CA CA002400497A patent/CA2400497A1/en not_active Abandoned
- 2001-02-08 AU AU2001234926A patent/AU2001234926A1/en not_active Abandoned
- 2001-02-08 WO PCT/US2001/004021 patent/WO2001058921A2/en active Application Filing
- 2001-02-08 JP JP2001558068A patent/JP2004508006A/en active Pending
- 2001-02-08 EP EP01907105A patent/EP1263452A4/en not_active Withdrawn
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