JP2004242720A - Drunken behavior evaluation method - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a method to evaluate objectively a condition of drunken behavior of a drinker by not only the depth of drunkenness but also various aspects including an exaltation feeling, a degree of excitement and a mood such as feeling good, bad or the like as well as a degree of relaxation which defers according to the constitution of strength against an alcoholic drink and a type of the alcoholic drink. <P>SOLUTION: An electrocardiogram of an examinee with alcoholic drinking is measured and a spectrum analysis of the electrocardiogram data is carried out. Then, the condition of drunkenness is evaluated by a variation of the heart rate (HR value) obtained from the result of the above analysis and comparison analysis of high-frequency spectral value (HF value) and a ratio of LF/HF (LF value: low-frequency spectral value) which is an index of an active mass of the sympathetic nerve before and after drinking. <P>COPYRIGHT: (C)2004,JPO&NCIPI

Description

【００３８】
以上の分析結果をまとめると次のようになる。
・飲酒後における心拍数（ＨＲ値）の変化は、酒に弱い被験者で大きく、酒に強い被験者で小さい傾向を示す。
・飲酒後におけるＨＦ値の変化は、酒に弱い被験者で大きくマイナスとなり、アルコールによるストレスが大きく、交感神経優位であることを示す。
・飲酒後における心拍変動、ＨＦ値変化量の大小及び変化曲線は、アルコール飲料の種別により異なり、またアルコール飲料の種別は、アルコールによるストレスや副交感神経優位の程度が異なることから、酔いの深さに影響を与えている。
【００３９】
また、上記試験で用いたスペクトル成分以外のＶＬＦ、ＵＬＦ等のスペクトル成分を用いて、同様に飲酒による酔いの状態との相関関係を示すことが可能であると考えられる。更に、飲酒後の血圧変化がアルコール飲料の種別により異なることと心拍数及びスペクトル解析結果とは関連していると考えられるので、飲酒時の血圧低下効果作用機序も、心電図データを解析したスペクトル成分から得られるものと考えられる。
【図面の簡単な説明】
【図１】呼気中アルコール濃度の消失曲線を被験者の酒に強い・弱い体質別に示す線図。
【図２】（Ａ）図は、酒に弱い被験者の呼気中アルコール濃度の消失曲線をアルコール飲料の種別に平均値で示す線図、（Ｂ）図は、酒に強い被験者の呼気中アルコール濃度の消失曲線をアルコール飲料の種別に平均値で示す線図。
【図３】飲酒後の最高血圧の経時変化をアルコール飲料の種別に示す線図。
【図４】飲酒後の心拍数（ＨＲ値）の経時変化を酒に強い・弱い体質別に示す線図。
【図５】飲酒後の副交感神経活動量（ＨＦ値）の経時変化を酒に強い・弱い体質別に示す線図。
【図６】飲酒後の心拍数（ＨＲ値）の経時変化をアルコール飲料の種別に示す線図。
【図７】飲酒後の副交感神経活動量（ＨＦ値）の経時変化をアルコール飲料の種別に示す線図。
【図８】図７のデータの内、清酒純米酒・清酒普通酒・米焼酎について飲酒後の副交感神経活動量（ＨＦ値）の経時変化を酒に強い・弱い体質別に示す線図。
【図９】飲酒後の副交感神経活動量（ＨＦ値）の経時変化を日本酒の種別に示す線図。
【図１０】交感神経活動量（ＬＦ／ＨＦ比）の経時変化をアルコール飲料の種別に示す線図。
【図１１】アルコール飲料の種別による心拍変動の特徴を示す図。
【図１２】被験者の印象に基づく酔いの強さと副交感神経活動量（ＨＦ値）の経時変化との相関関係を示す図。
【図１３】被験者の印象に基づく「飲みたい」欲求と交感神経活動量（ＬＦ／ＨＦ比）の経時変化との相関関係をアルコール飲料の種別に示す図。[0001]
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a technique for objectively evaluating the state of sickness due to drinking from various aspects.
[0002]
[Prior art]
2. Description of the Related Art Conventionally, in order to determine a drinking state of a driver of a vehicle, a method of measuring an alcohol concentration in breath of the driver using an alcohol sensor and making a determination based on the measured value has been widely adopted. Such drinking state detection devices are described in, for example, Patent Documents 1 and 2 below.
[0003]
Patent Document 3 discloses an apparatus that clearly notifies a state of sickness according to the amount and type of drinking. The device of the document, the pulse or heart rate of the subject, the blood alcohol concentration calculated from the alcohol concentration in the breath, or the amount of alcohol drunk, based on the blood alcohol concentration calculated from the passage of time, based on the drunk state, It is displayed in several stages.
[0004]
[Patent Document 1] JP-A-6-50918 [Patent Document 2] JP-A-9-292354 [Patent Document 1] JP-A-9-168516 [0005]
[Problems to be solved by the invention]
It is empirically known that the state and degree of drunkness due to drinking generally depend not only on the amount of drinking but also on the type of drinking and the constitution of drinkers who are described as “strong” or “weak” in so-called drinking. Have been. It is also said that, depending on the type of sake, for example, sake and shochu or beer differ in how to get drunk. However, the above-mentioned conventional apparatuses are all for simply judging the depth of sickness on a fixed basis, and are not for judging / evaluating different sickness methods depending on the constitution of the drinker and the type of drink. Absent.
[0006]
Therefore, the present invention has been made in view of the above-described conventional problems, the purpose is not only the state of the drunkenness of the drinker, not only the depth of the drunkenness, the elation different depending on the constitution and the type of alcohol, It is an object of the present invention to provide a method for objectively evaluating various aspects including a degree of excitement, comfort such as a bad mood, and a degree of relaxation.
[0007]
[Means for Solving the Problems]
According to the present invention, in order to achieve the above object, there is provided a drunkness evaluation method characterized by measuring an electrocardiogram of a drunk subject and evaluating a state of sickness using the electrocardiogram data.
[0008]
Further, a spectrum analysis of the electrocardiogram data is performed, and the state of sickness can be evaluated using the analysis result.
[0009]
In one embodiment, among the spectral components obtained from the electrocardiogram spectral analysis, a high-frequency spectrum value (HF value) as an index of the amount of parasympathetic nerve activity and an LF / HF ratio (LF value: an index of the amount of sympathetic nerve activity: The evaluation is performed by comparing the low-frequency spectrum values before and after drinking. Furthermore, changes in the heart rate (heart rate variance = HR value) obtained from the electrocardiogram differ depending on the type of alcohol and the constitution of the drinker, who is strong or weak in alcohol, and the state of sickness is evaluated using this. be able to.
[0010]
In particular, since the HF value also serves as an index of the degree of relaxation, the comfort of sickness can be determined based on the magnitude of the change after drinking. Since the LF / HF ratio is an index of excitement, elation, or diplomatic symptoms (during cheerfulness or depression) at the time of drinking, by comparing the degree of change of the LF / HF ratio before and after drinking. It is an index for determining a pleasant mood when drinking. Further, other spectral components (VLF, ULF, etc.) are also considered to be components having a correlation with the drinking state, and it is possible to evaluate using these components.
[0011]
As described below, according to the test results performed by the inventors of the present application, when comparing the state of sickness due to various alcoholic beverages, the result of investigating the impression degree of sickness felt by each subject after the test and the HF value, Since a correlation is recognized between the LF / HF ratio, the state of sickness can be objectively evaluated by evaluating these values. In addition, the difference between the constitutions generally called “weak to alcohol” and “strength to alcohol” could not be clearly distinguished from the measurement result of the alcohol concentration in breath, but the HF value and LF / It was confirmed that the HF ratio and the heart rate variability (HR value) tended to be clearly different between both constitutions.
[0012]
Therefore, by using the evaluation method of the present invention, differences in the weak or strong constitution of alcohol and the difference in the state of sickness thereby become apparent, and different alcoholic beverages are developed according to the constitution of the drinker, or Makes it possible to search for liquor qualities that are more enjoyable for the elderly.
[0013]
BEST MODE FOR CARRYING OUT THE INVENTION
The present inventors applied a total of 12 subjects of male and female subjects to a total of 8 subjects of sake junmai sake, raw material alcohol, rice shochu (distilled liquor), beer, wine, sake liquor, sake ginjoshu, and sake nigori (honjozo). The state of sickness was tested as follows using various types of alcoholic beverages as test liquors.
Test method:
The subject drank each test liquor of 300 ml (per 60 kg body weight) in terms of alcohol 13.5% within about 15 minutes after about 1.5 hours had passed after lunch. Electrocardiograms were recorded from about 30 minutes before drinking to before dinner. Five minutes after the end of drinking, the breath alcohol concentration was measured. All measurements were completed approximately 4-5 hours after the start of drinking.
Measurement and analysis method:
(1) Breath alcohol concentration: Measured about every 5 minutes using a commercially available alcohol concentration measuring device.
(2) Heart rate measurement: using a Holter-type electrocardiograph and an electrocardiogram analyzer “DSC-3100” (manufactured by Nihon Kohden Corporation).
(3) Analysis of heart rate: Spectrum analysis software "MemCalc" (manufactured by GMS) was used.
(4) Questionnaire Survey: Each subject's consciousness and mood during the test were divided into (1) 30 minutes after drinking, (2) 1 hour after drinking, (3) 2 hours after drinking, and (4) 3 hours after drinking. Questionnaire.
[0014]
Hereinafter, the test results will be described in detail with reference to the attached part. Prior to the test, each subject was subjected to a patch test to check for the presence or absence (high or low activity) of alcohol metabolite, acetaldehyde-degrading enzyme. It was classified as "weak" constitution (patch test "+").
[0015]
FIG. 1 shows the disappearance of breath alcohol concentration in a test subject after drinking.
The tendency of the subjects to lose their breath alcohol concentration was divided into three types. In the figure, the subjects with the strong constitution of alcohol shown by the thick solid line disappear quickly within 4 hours, and the subjects with the constitution weak to alcohol shown by the thick two-dot chain line disappear very slowly, more than 5 hours after drinking. Alcohol was also detected during exhalation. The third type shown by a thin solid line was the tendency observed in the subjects of the patch test “−” with a low drinking frequency and the subjects of the patch test “+” with a heavy drinking habit.
[0016]
FIG. 2A shows the average of the progress of alcohol concentration in breath after drinking in a test subject weak to alcohol in the patch test (+) for each type of alcoholic beverage. There was a difference in the tendency of the alcohol in the breath to disappear up to about 2 hours after drinking, depending on the type of alcoholic beverage. However, thereafter, the disappearance rate was almost the same in all the alcoholic beverages, and it tended to take about 4 to 5 hours to reach the detection limit of 0.05 μg / ml or less.
[0017]
FIG. 2 (B) shows the average of the progress of alcohol concentration in breath after drinking in a test subject who is strong in alcohol in the patch test (-) for each type of alcoholic beverage. Unlike the test subject weak in alcohol shown in FIG. 2 (A), the tendency of disappearing alcohol during breathing did not differ depending on the type of alcoholic beverage, and almost reached the detection limit 4 hours after drinking. As described above, when the same amount of alcohol is consumed in terms of pure alcohol, it is understood that the alcohol metabolism tendency obtained from the breath alcohol concentration is not significantly affected by the type of alcoholic beverage.
[0018]
FIG. 3 shows the change over time in blood pressure according to the type of alcoholic beverage in the case of a test subject who is strong in alcohol and has no difference in alcohol disappearance tendency. In general, blood pressure tended to decrease after drinking. There was a difference in the degree of decrease in blood pressure depending on the type of alcoholic beverage, and after 2 hours of drinking, sake dropped about 2.5 times as much as rice shochu, which had not decreased the least. Among Japanese sake, Junmaishu and ordinary sake in particular declined significantly. Although not shown, although the diastolic blood pressure was smaller than that of the systolic blood pressure, a difference was observed in the degree of blood pressure decrease depending on the type of alcoholic beverage. Also in that case, Junmaishu and ordinary sake tended to significantly lower blood pressure. However, for any of the alcoholic beverages, no significant correlation was observed between the systolic or diastolic blood pressure and the breath alcohol concentration.
[0019]
Here, the relationship between alcohol intake and blood pressure change will be considered as follows.
Alcohol taken into the body is metabolized to acetaldehyde in the liver, but those who are vulnerable to the patch test (+) have no or little acetaldehyde-degrading enzyme, so the blood acetaldehyde concentration increases and the patch test (- Even people who are strong in alcohol can accumulate in the blood if the decomposition of acetaldehyde cannot keep up with alcohol intake. When the amount of acetaldehyde in the blood increases, the blood works to promote the secretion of catecholamine, another substance that causes hangover. Acetaldehyde is said to be highly toxic and a cause of a hangover.On the other hand, as reported by Professor Okuda of Kumamoto Prefectural University, its metabolite has a vasodilator effect, and acetaldehyde is found in the cardiac sympathetic nervous system. Has a sympathetic-like effect, and the present inventors speculated that it might affect blood pressure changes. Further, since the blood pressure change and the heart rate variability are related, the inventors of the present application thought that the degree of the sickness can be verified and evaluated by using a numerical value related to the heart rate variability.
[0020]
Further, the sympathetic nerve and the parasympathetic nerve will be described. In the cardiac autonomic nervous system, the sympathetic nerve and the parasympathetic nerve have opposing actions. In general, when awake during the day, the sympathetic nerves work actively and the parasympathetic nerves are suppressed, while on the other hand, when sleeping at night, the parasympathetic nerves become active and the sympathetic nerves are suppressed. In addition, it has been reported that the parasympathetic nerve increases when listening to music or smells good scent, and is an index indicating the degree of relaxation.
[0021]
Alcohol drinking causes the sympathetic nervous system to be affected by acetaldehyde, leading to the main symptoms of intoxication: flushing the face, tachycardia, sweating, slimy mouth, and dazzling. In contrast, the parasympathetic nervous system is affected by alcohol and feels relaxed due to symptoms such as pale face, pupillary constriction, bradycardia, and cerebral palsy caused by the anesthetic effect of alcohol. Then, it is considered that which one of these two nervous systems is stronger determines whether the person is drunk or not.
[0022]
As described above, since the blood pressure significantly changes (decreases) after alcohol drinking, acetaldehyde is involved in the fluctuation of blood pressure, and alcohol and acetaldehyde are involved in the parasympathetic nervous system. It has been decided that it is possible to use heart rate variability as a means for objectively considering the state and degree of sickness from various aspects such as sickness. This will be discussed in more detail below.
[0023]
The following electrocardiogram data can be obtained by performing a spectrum analysis of the heart rate variability from an electrocardiogram measured from a subject using a Holter-type electrocardiograph.
Heart rate variability spectrum analysis value:
HR (b / min): heart rate per minute.
HF (ms · ms): High frequency range (0.15 to 0.40 Hz). It indicates the amount of parasympathetic activity corresponding to the respiratory cycle. If this value is high, it is understood that the subject is in a relaxed state.
LF (ms · ms): low frequency range (0.04 to 0.15 Hz). It mainly relates to body temperature regulation and blood pressure fluctuation, and indicates the amount of sympathetic nerve activity, but also includes the amount of parasympathetic nerve activity.
LF / HF ratio: indicates the amount of sympathetic nerve activity in which the influence of the parasympathetic nerve is minimized from the LF value. When this value is high, it indicates a state of conscious excitement (elevation).
[0024]
First, the heart rate variability (HR) of the test subjects weak in the patch test (+) and the test subjects in the patch test (-) was measured when the same amount of alcohol was consumed.
FIG. 4 shows a change in heart rate after drinking the same amount of sake Junmai sake. In subjects vulnerable to alcohol, the heart rate increased after drinking and it took more than 3 hours to return to the state before drinking, whereas in subjects strong in alcohol, the heart rate decreased a short time after drinking, Thereafter, a tendency to become substantially constant was observed.
[0025]
FIG. 5 shows the change in HF value after drinking the same amount of sake Junmai sake. The HF value serving as an index of relaxation tends to increase periodically in a person who is strong in alcohol, indicating a relaxed and good sickness state. On the other hand, in the case of a subject weak to alcohol, the HF value decreased, and became almost 0 in about 1 hour, and felt stress, but gradually increased after about 1 hour since he fell asleep. Thus, it was confirmed that the state of sickness was related to the analysis value obtained from the heart rate variability.
[0026]
Furthermore, the difference according to the type of alcoholic beverage was analyzed. Note that each of the data described below has a value of 0 at the end of drinking and is indicated by a change value from the end of drinking.
[0027]
FIG. 6 shows the change over time of the heart rate (HR value) after drinking, depending on the type of alcoholic beverage. The heart rate (HR) after drinking showed a different tendency depending on the type of alcoholic drink in the amount of change and the change over time. In the case of sake, as in normal times, there was a periodicity in which it increased immediately after drinking, then decreased, and then increased. Drinking wine and beer showed the least change, while drinking rice shochu and raw alcohol drastically decreased. The reason why the amount of alcohol that contains no amino acids or other raw materials or sake that has a low level of taste is greatly reduced by the activation of the parasympathetic nervous system by alcohol, and in sake, wine, and beer that contain many components other than alcohol, It is thought that there is a component that hinders the action of this alcohol.
[0028]
FIG. 7 shows changes over time in the amount of parasympathetic nervous activity (HF value) after drinking, by type of alcoholic beverage. Regarding the HF value, which is an index of relaxation, differences were observed in the amount of change and the change over time depending on the type of alcoholic beverage. It is understood that the change amount of the HF value is the smallest when drinking rice shochu, and the change with time is the closest to normal when drinking sake, and it is understood that stress during drinking is easily eliminated. In addition, in the case of raw material alcohol, it changes to the most negative side after drinking, and it is considered that stress is large.
[0029]
FIG. 8 shows the results of comparing these changes in the HF value according to the constitution of the subject.
When the same alcoholic beverage is ingested, it can be understood that the subject of the type that is clearly weak in alcohol has a large change in the HF value on the negative side, and feels more stress.
In addition, in the case of rice shochu, it can be seen that the difference in the amount of change between a subject who is strong in sake and a weak subject is smaller than that in the case of sake. Therefore, it is understood that the state of sickness can be objectively evaluated from the viewpoint of the stress indicated by the HF value.
[0030]
FIG. 9 shows changes over time in the amount of parasympathetic nervous activity (HF value) after drinking, depending on the type of sake. From the change of HF value when four kinds of sake were used, Junmaishu, Ginjoshu, ordinary sake, and Honjozo, it was recognized that the HF value related to the degree of relaxation had a difference depending on the type of the same sake.
[0031]
FIG. 10 shows the change over time in the amount of sympathetic nerve activity (LF / HF ratio) depending on the type of alcoholic beverage. The LF / HF ratio, which indicates the amount of sympathetic activity, increased after drinking, and the amount of change tended to differ depending on the type of alcoholic beverage. In particular, in the case of pure rice sake, it was higher than usual after drinking, indicating that the person became excited. On the other hand, beer and regular sake have the least change, and it seems that there is almost no excitement due to sickness. In addition, the LF / HF ratio showed a tendency to decrease after 200 minutes from the start of measurement when the breath alcohol concentration was lowered to its detection limit.
[0032]
From the above analysis results, changes in heart rate, changes in HF value and LF / HF ratio after drinking indicate the state of sickness, not only the depth of sickness, but also a feeling of elation and excitement that differ depending on the constitution and type of alcohol. It can be understood that the object is objectively shown from various aspects including comfort such as feeling bad and relaxation, and a degree of relaxation.
[0033]
In addition, in relation to heart rate variability, the alcoholic beverages used in this test had the characteristics shown in FIG. 11 depending on the type. Sake Junmaishu showed a tendency that was significantly different from rice shochu, and rice shochu tended to be close to wine. Sake ordinary sake showed a tendency close to that of beer, and apart from the effect of lowering blood pressure, which is a characteristic of sake, also showed a tendency close to rice shochu.
[0034]
Finally, in order to investigate the relationship between the impression that the subject actually felt and the measured value, after a series of tests, each subject was questionnaire surveyed about the impression of each alcoholic beverage, and the results and The measured and analyzed values of electrocardiogram data were compared and examined. FIG. 12 shows the correlation between the intensity of sickness based on the subject's impression and the change over time in the amount of parasympathetic nerve activity (HF value). In the figure, the value of 270 minutes after drinking was selected as the central value in the time course of the intensity of sickness and the amount of parasympathetic nerve activity (HF value). As a result, a positive correlation was found between the strength of the sickness and the HF value of the test subject who was vulnerable to alcohol at a risk rate of 5%. This was because, in the case of subjects weak to alcohol, the alcohol concentration in the breath was as low as 0.1%. Even after 270 minutes after drinking, the HF value was low, and the nervous state due to alcohol was dragged. It seems to be.
[0035]
Further, FIG. 13 shows the correlation between the desire to “drink” based on the subject's impression and the change over time in the amount of sympathetic nervous activity (LF / HF ratio) according to the type of alcoholic beverage. As shown in the figure, a certain correlation was observed between the desire to “drink” and the LF / HF ratio. In subjects weak to alcohol, the LF / HF ratio and the desire or mood to “drink” showed a positive correlation at a risk rate of 5%, and in subjects strong to alcohol, a negative correlation was observed at a risk rate of 5%. Was. Thus, there was a tendency that those who are strong in alcohol prefer alcoholic beverages having an increased LF / HF value, and those who are weak in alcoholic beverages prefer alcoholic beverages having a low LF / HF value. In the same alcoholic beverages, sake and rice shochu showed the same level of desire to drink, regardless of their strong or weak constitution, but the impressions of wine and beer were completely different .
[0036]
From the above, the subjects who are strong in alcohol and those who are weak in alcohol have different sickness states when drinking the same amount, and the HF value as an index of the amount of change in heart rate and the degree of relaxation is shown in Table 1 below. It turned out to be clearly different as shown.
[0037]
[Table 1]

[0038]
The above analysis results are summarized as follows.
The change in heart rate (HR value) after drinking tends to be large in subjects weak to alcohol and small in subjects strong to drinking.
-The change in the HF value after drinking was significantly negative in subjects weak to drinking, indicating that stress due to alcohol was large and the sympathetic nerve was dominant.
・ The heart rate variability, the magnitude of the change in HF value, and the change curve after alcohol drinking differ depending on the type of alcoholic beverage, and the alcoholic beverages differ in the degree of stress and parasympathetic superiority due to alcohol. Is affecting.
[0039]
In addition, it is considered that it is possible to similarly show a correlation with the state of sickness due to drinking using spectral components such as VLF and ULF other than the spectral components used in the above test. Furthermore, since it is considered that the change in blood pressure after drinking differs depending on the type of alcoholic beverage and the results of heart rate and spectrum analysis, the mechanism of the blood pressure lowering effect during drinking is also determined by analyzing the electrocardiogram data. It is believed to be obtained from the components.
[Brief description of the drawings]
BRIEF DESCRIPTION OF DRAWINGS FIG. 1 is a diagram showing disappearance curves of exhaled alcohol concentration according to a subject's strong and weak constitutions for alcohol.
FIG. 2 (A) is a diagram showing an average of the disappearance curve of the alcohol concentration in breath of a subject who is vulnerable to alcohol, and FIG. 2 (B) is a diagram showing the alcohol concentration in breath of a subject who is vulnerable to alcohol. FIG. 3 is a diagram showing the disappearance curve of the average of the types of alcoholic beverages.
FIG. 3 is a diagram showing the change over time in systolic blood pressure after drinking, according to the type of alcoholic beverage.
FIG. 4 is a diagram showing changes over time in heart rate (HR value) after drinking for each of the strong and weak constitutions of alcohol.
FIG. 5 is a graph showing changes over time in the amount of parasympathetic nervous activity (HF value) after drinking, according to the strong and weak constitutions of drinking.
FIG. 6 is a diagram showing a temporal change of a heart rate (HR value) after drinking, for each type of alcoholic beverage.
FIG. 7 is a diagram showing changes over time in the amount of parasympathetic nervous activity (HF value) after drinking, for each type of alcoholic beverage.
8 is a diagram showing, with respect to the data of FIG. 7, changes over time in the amount of parasympathetic nervous activity (HF value) of sake junmai sake, sake ordinary sake, and rice shochu after drinking, for each of strong and weak constitutions.
FIG. 9 is a diagram showing the time course of parasympathetic nervous activity (HF value) after drinking for each type of sake.
FIG. 10 is a diagram showing changes over time in the amount of sympathetic nerve activity (LF / HF ratio) for each type of alcoholic beverage.
FIG. 11 is a diagram showing characteristics of heart rate variability according to types of alcoholic beverages.
FIG. 12 is a diagram showing a correlation between the strength of sickness based on the subject's impression and the change over time in the amount of parasympathetic nerve activity (HF value).
FIG. 13 is a diagram showing the correlation between the desire to “drink” based on the impression of the subject and the change over time in the amount of sympathetic nerve activity (LF / HF ratio) for each type of alcoholic beverage.

Claims (2)

A drunkenness evaluation method, comprising: measuring an electrocardiogram of a drunk subject, and evaluating a state of sickness using the electrocardiogram data. The method of evaluating a motion sickness according to claim 1, wherein a spectrum analysis of the electrocardiogram data is performed, and a state of motion sickness is evaluated using the analysis result.

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