JP2004237051A - Blood vessel visualizing method and apparatus - Google Patents

Blood vessel visualizing method and apparatus Download PDF

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JP2004237051A
JP2004237051A JP2003068898A JP2003068898A JP2004237051A JP 2004237051 A JP2004237051 A JP 2004237051A JP 2003068898 A JP2003068898 A JP 2003068898A JP 2003068898 A JP2003068898 A JP 2003068898A JP 2004237051 A JP2004237051 A JP 2004237051A
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light
blood
device
skin
reflected
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Yasuhiro Horiike
Jun Kikuchi
Hiroki Ogawa
靖浩 堀池
洋輝 小川
純 菊地
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Yasuhiro Horiike
Jun Kikuchi
Ogawa Hiroteru
靖浩 堀池
洋輝 小川
純 菊地
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0059Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150053Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150106Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced
    • A61B5/15016Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced by accessories for bringing the piercing element into the body, e.g. through rotation of the piercing element
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150236Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150244Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150503Single-ended needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150748Having means for aiding positioning of the piercing device at a location where the body is to be pierced
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4887Locating particular structures in or on the body
    • A61B5/489Blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/742Details of notification to user or communication with user or patient ; user input means using visual displays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/427Locating point where body is to be pierced, e.g. vein location means using ultrasonic waves, injection site templates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion

Abstract

<P>PROBLEM TO BE SOLVED: To solve a problem of an unavoidable physical pain of a person to be taken blood who is compelled to put on a tourniquet and distend the blood vessel for confirming the position of the blood vessel in collecting the blood from the person. <P>SOLUTION: At least, a light containing wavelength components of at least 600-1,200 nm is applied on the skin surface for obtaining am image of the blood vessel right under the skin of the person and confirming the puncture position of a blood collecting needle. The spatial distribution of the intensity of the reflected light of the light once entering into the body and intruding deeper than the blood vessel is observed. This method can reduce the effects of the light directly reflected on the skin surface and the light entering into the body but reflected to the outside from the body before reaching the blood vessel. <P>COPYRIGHT: (C)2004,JPO&NCIPI

Description

【0001】 [0001]
【発明の属する技術分野】 BACKGROUND OF THE INVENTION
本発明はヒトの皮下にある血管から中空の針を介して体外へと血液を採取する際の血管可視化方法ならびに装置に関する。 The present invention relates to a blood vessel visualization method and apparatus when collecting blood into the extracorporeal through the hollow needle from the blood vessels under the skin of a human.
【0002】 [0002]
【従来の技術】 BACKGROUND OF THE INVENTION
従来、注射法による静脈血の採取は、駆血帯と呼ばれる弾力性を有するゴム状の紐を腕に巻きつけ、一時的に血流を制限したときに皮膚上に浮き出た静脈を狙い、注射針を当該静脈に穿刺し、その後に減圧吸引して血液を注射筒に引き込んでいた。 Conventionally, the collection of venous blood by injection method, wrapped arms rubbery cord having elasticity called tourniquet temporarily aim veins stand out on the skin when the limit blood flow, injection the needle is punctured into the vein, then the vacuum suction to had drawn into syringe blood.
【0003】 [0003]
また近年、微小な採血用針を備え、微細な溝流路や種々の分析器、分析装置を配置した数mmから数cm四方のチップ状血液分析装置が開発されている。 In recent years, with a small blood collecting needle, fine flute and various analyzers, chip-shaped blood analysis apparatus several cm square from a few mm with the analyzer is arranged it has been developed. (特開2001−258868)このようなチップ状の血液分析装置の針を被験者の皮膚に穿刺し、皮下の血管から血液を採取してこれをチップ上に引き込み、そこで血液中の種々の生化学物質(ナトリウム、カリウムイオン、グルコース、尿素窒素、クレアチニンなど)の濃度を分析する。 (JP 2001-258868) and the puncture needle to the skin of the subject in such a chip-shaped blood analysis device, which pull on the chip by collecting blood from the subcutaneous blood vessel, where the various biochemical blood analyzing the concentration of a substance (sodium, potassium ion, glucose, urea nitrogen, creatinine, etc.). 当該チップは人々が自宅で用い、健康管理に役立てることを想定して開発されたものである。 The chip is what people used at home, has been developed to provide to help health care.
【0004】 [0004]
【発明が解決しようとする課題】 [Problems that the Invention is to Solve
通常の血液採取時に用いられる駆血帯は、上でも述べたように皮膚上に血管を浮き出させて、採血を行う人が注射針を穿刺する部位を特定するために行っている。 Tourniquets used during normal blood collection is vascular was embossed on the skin As described above, the person performing the blood sampling is performed in order to identify the site of puncture needle. この駆血帯を腕に巻きつけ、圧迫することは注射針を穿刺したときの疼痛とともに被血液採取者に及ぼす苦痛の一つである。 Wound the tourniquet on the arm, adding pressure is one of pain on with pain upon puncturing the injection needle to be blood collection person.
【0005】 [0005]
また、チップ状の血液分析装置においては、まず、できるだけ穿刺時の疼痛を抑制するために針の径が細くなっている(例えば外径100μm、内径50μm)ために、剛性(挫屈強度)が非常に低くなっている。 Further, in the chip-shaped blood analysis apparatus, first, as far as possible the diameter of the needle in order to suppress the pain upon puncturing is thinner (e.g., outer diameter 100 [mu] m, an inner diameter of 50 [mu] m) for rigidity (buckling strength) It is very low. このような強度低下を実効的に緩和するために、針の全長は短くすることが望まれ、またこのような要望は採取時に針内部に残留し、分析に用いられない血液量を少なくするという観点からも重要である。 Such reduction in strength to effectively alleviated, the total length of the needle is desirable to shorten and that such requests, the needle inside the remaining time of collection, to reduce is not the amount of blood used in the analysis it is also important from the point of view. このように針の長さが短くなると、チップ自体も採血時に皮膚近傍まで近寄ることになり、当該チップは被験者自らが採血を行うことを想定しているので、血管を肉眼で見ることが困難となるという問題があった。 With such shorter length of the needle, it will be come close to the vicinity of the skin at the time the chip itself blood, since the chip is assumed that the own subjects collecting blood, is difficult to see the vessel with the naked eye there is a problem that becomes.
【0006】 [0006]
また特願2001−319992に示されているように、針を皮膚に穿刺する際に、痛みを緩和する目的で針近傍の皮膚の雰囲気を減圧として皮膚を盛り上げ、そのとき針を自動的に皮膚に穿刺させる場合には、特に血管を見ることが難しくなり、場合によっては針を血管へと導くことができずに採血ができないという問題があった。 As also shown in Japanese Patent Application No. 2001-319992, when the puncture needle into the skin, boost the skin atmosphere skin needle near the purpose of alleviating pain as vacuum, automatically skin that when needle in the case of puncturing, especially difficult to see the blood vessel, the needle was a problem that can not be bled can not lead to the vessel in some cases.
【0007】 [0007]
上述のように、通常の注射による採血時の駆血帯による不快感の抑制や、チップ状の血液分析装置を用いたときの採血者である被験者が血管位置を確認しながら確実に採血するためには、針を皮膚に穿刺する際に血管位置を何らかの手法で監視しなければならない。 As described above, inhibition and discomfort due to tourniquet during blood sampling by conventional injection, since the subject is a blood donor when using chip-like blood analyzer is surely blood while confirming the position of the blood vessel , the needle must be monitored vessel position by some method at the time of puncturing the skin.
【0008】 [0008]
このような目的でこれまでいくつかの血管可視化の手法が公知となっている。 Such previous several vascular visualization techniques for the purpose are known. これらの公知例の多くは、体外から体内へと光を導き、その反射光や透過光から血管情報を得るというものである。 Many of these known examples, into the body from outside and guides light, is that obtaining blood vessel information from the reflected light or transmitted light. 例えば比較的厚さが小さい指や手の甲などに波長が700から1200nmの近赤外光を照射し、その裏側にCCD(Charge Coupled Device)のような撮像素子を配置して体内を透過してくる光の強度の空間分布を観察する。 For example relatively wavelengths like a small finger or the back of the hand thickness was irradiated with near-infrared light 1200nm from 700, coming through the body by placing the imaging element such as a CCD (Charge Coupled Device) on its rear side observing the spatial distribution of the intensity of light. (特開平8−164124)このような近赤外光は、比較的人体を構成する水や血液中のヘモグロビンなどによる吸収係数が小さく透過しやすいため用いられることが多い。 (JP-A 8-164124) this near-infrared light is relatively such as by the absorption coefficient of hemoglobin in the human body structure to water or blood is often used for easily transmitted smaller. また血管部を透過してくる光は血液中の水やヘモグロビン濃度が他の部位よりも高いために透過してくる光は吸収により強度が弱くなっているために像は暗くなるが、その他の部分を透過してくる光は比較的吸収されずに強度が強いので明るい像が得られる。 The light transmitted through the blood vessel portion is image becomes darker because the strength is weakened by to come light absorbing transmissive to greater than site water or hemoglobin concentration of other blood, other light transmitted through the part, because strength is strong bright image is obtained without being relatively absorbed. したがって血管像が得られることになる。 Hence the blood vessel image is obtained.
【0009】 [0009]
上で述べたような近赤外光の透過による血管像の導出は、実際には光源の強度の制約から指や手の甲などの比較的肉厚が薄い部分でのみしか用いることができない。 Derivation of the blood vessel image by transmission of near infrared light as described above is only possible to use only a relatively small wall thickness portions of the fingers or the back of the hand the limitation of the intensity of the light source in practice. 特によく採血時に用いられる上腕や前腕部では十分な強度の光を透過させることは難しい。 Especially to be difficult transmits light of sufficient intensity can be a brachial or forearm used during blood collection. そこで光を人体に照射して一旦侵入してから再度照射表面から反射してくる光を撮像素子によって捉え血管像を得るという方法も公知となっている。 How the light reflected So again from the irradiation surface after entering once by irradiating light to the human body of obtaining blood vessel image captured by the imaging device has also become known. (特開平8−164125)このような反射光を用いた場合、直接皮膚表面で反射してくる光の強度が強く、一旦人体に入り込んでから再度人体から反射して出てくる光強度は比較的弱いので、血管情報を含む光(一旦人体に入り込んでから反射してきた光)のみを捉えるために、本公知例の場合光を照射する皮膚表面に液体を塗布して直接反射光を低減するようにしている。 When using the (JP-A 8-164125) such reflected light, strong intensity of light reflected directly the skin surface, once the light intensity emerging and reflected again from the human body from enters the human body comparison since target weak, in order to capture only the light (once light reflected from enters the human body) containing vessel information, to reduce the direct reflection light by applying a liquid to the skin surface that irradiates when the light of the known example It is way. また400から600nmと600から800nmと波長の異なる2種類の光を皮膚に照射して、前者が後者に比較して一旦体内に侵入してから再度反射してくる光の成分が少ないことを利用し、両者で得られた画像を引き算して血管像を得るという方法も公知になっている。 The use of the two kinds of light different from 400 to 600nm and 600 of 800nm ​​wavelength was irradiated to the skin, it former small component of light reflected again enter the body once compared to the latter and, a method that subtracts the images obtained in both obtaining blood vessel image in the public domain. (特開平8−164123) (JP-A-8-164123)
【0010】 [0010]
以上述べたように光を用いて血管像を得る場合に、透過法では適用可能な部位が限られるという問題があった。 Or in the case of obtaining a blood vessel image using light as described, the transmission method applicable site there is a problem that limited. また反射法を用いた場合には皮膚表面から直接反射してくる光を抑制するために皮膚表面に液体を塗布するというような煩雑な手間を要したり、2種類の光源、フィルター、ダイクロックミラー、画像解析機構などから構成される高価、複雑な装置が必要されるという問題があった。 Also it takes a complicated labor such as applying a liquid to the skin surface in order to suppress the light reflected directly from the skin surface in the case of using the reflection method, two kinds of light sources, filters, dichroic mirror, image analysis mechanism such as expensive composed, is complicated apparatus has a problem that is needed.
【0011】 [0011]
本発明が解決すべき課題は、被採血者に肉体的な負荷をかけることなく皮下の血管位置を安価な装置を用い、的確に把握する手段を提供することにある。 Problems to be solved by the present invention is, using an inexpensive device vascular position subcutaneous without applying physical load on the blood donor, it is to provide a means to accurately grasp.
【0012】 [0012]
【課題を解決するための手段】 In order to solve the problems]
上述したように光を体内へと導き血管像を得る場合、像を得る部位を選ばない反射法を用いるほうが望ましい。 To obtain a blood vessel image leads to the body of the light as described above, we find that using the reflection method agnostic site to obtain an image is desirable. 図1にはヒトの前腕部101にLED(Light Emitting Diode)102を光源として照射し、そのとき反射してくる光をCCD(Charge Coupled Device)104などの撮像素子によって捉え、その像をモニタ105に表示するシステムを示している。 In Figure 1 a LED (Light Emitting Diode) 102 is irradiated as the light source to the forearm 101 of the person, capturing the light that time comes reflected by the CCD (Charge Coupled Device) 104 imaging device such as a monitor 105 and the image shows the system to be displayed in. このとき用いる光の波長は、比較的皮膚の色素、血中ヘモグロビン、水などの皮膚や血管を構成する化合物に由来する吸収係数が低い600から1200nmのものを用いる。 The wavelength of light used at this time, used as the 1200nm relatively skin pigment, blood hemoglobin, from 600 absorption coefficient is low derived from the compound constituting the skin and blood vessels, such as water. 図2にはこのときの体内での光の伝播の様子を模式的に示している。 Schematically shows a state of light propagation in the body at this time in Fig. ここで既述の語句と同一のものは同じ符号を用いている。 Here the same as the phrase already described have the same reference numerals. (以下、同様)このように照射された光は皮膚表面で反射した光204と一旦体内へと侵入して拡散、反射しながら再度体外へと反射してくる光205とがあり、両者がCCD104によって捉えられる。 (Hereinafter the same) thus light irradiated once spread penetrate into the body and the light 204 reflected by the skin surface, there is a light 205 coming reflected again to the outside while being reflected, both CCD104 It captured by. この205の光のように皮膚表面近傍の血管(多くは静脈)下に一旦浸透してから再度皮膚外へと反射してくる光に血管情報が含まれ、血管部分では水、ヘモグロビンに由来する光吸収がその他の部分よりも大きいために、血管像は黒くモニタ上に浮き上がる。 Vessel information to light (many venous) blood vessels near the skin surface comes reflected to once penetrate again skin out from underneath like this 205 of the light include, in blood vessel portion from water, hemoglobin for the light absorption is greater than other portions, the blood vessel image floats on the black monitor. しかしながら実際には直接反射光204の強度が大きいために205のような光の情報はこれに重畳して隠れてしまい、モニタ上には血管像は現れない。 However actually hides superimposed direct light information, such as 205 in the strength is greater the reflected light 204 in this, on the monitor does not appear blood vessel image.
【0013】 [0013]
そこで本発明者らは簡易かつ安価にこの直接光の影響を低減するために、図3に示すような直接反射光遮光装置301を用い直接反射光を抑制することを試みた。 The present inventors have in order to reduce the effect of easily and inexpensively this direct light, it tried to suppress the direct reflected light with the directly reflected light shading device 301 as shown in FIG. この装置は貫通穴302にLED102が挿入されており、これを図4に示すように血管観察部位近傍の皮膚表面に押し当てる。 The device is inserted LED102 the through hole 302, pressed against which the vessel observed region near the skin surface, as shown in FIG. このとき直接反射光遮光装置301の少なくとも表面はLED102が放射する光の波長に対して透過性を有さないような材料を用いることが望ましい。 It is desirable at least the surface at this time direct reflection light shielding device 301 that LED102 can use a material that does not have a transparent to the wavelength of light emitted. 図4においてLED102を照射すると、図2の場合と同様に光は一旦体内へと浸透する成分と皮膚表面で直接反射する成分とに分かれるが、このような装置301を用いた場合には装置自身が、直接反射光204を遮光するためにCCD104に捉えられることは無い。 Upon irradiation with LED102 4, but divided into a component reflected directly in the case of as well as the optical component and the skin surface for temporarily penetrate into the body 2, the apparatus itself in the case of using such a device 301 but it is not to be taken in CCD104 to shield the direct reflected light 204. また、一旦体内に浸透するものの皮膚表面直下の血管下まで到達せずに反射してしまう光401は同様に装置自身に遮光され、体外に出ることは無い。 Further, once the light 401 resulting in reflected without reaching the vessel under just below the skin surface of which penetrate into the body is blocked in the same way device itself, never out of the body. 結局体外へと放射される光は一旦体内へと浸透してから皮膚表面直下の血管下まで到達してから再度体外へと出てくるもの205であり、この光はCCDカメラ104に捉えられ、血管部は水、ヘモグロビン等に由来する吸収のため光強度が弱く、それ以外の部位は比較的光強度が強いためにモニタ105上には血管像が暗く浮き出ることになる。 Eventually the light emitted into the outside is 205 which comes out again to the outside after reaching once from penetrating into the body until the blood vessel under just below the skin surface, the light is trapped in the CCD camera 104, vascular part water, weak light intensity for the absorption derived from hemoglobin or the like, so that stand out dark and blood vessel image on the monitor 105 to other sites relatively light intensity strong. そしてこの血管像を見ながら注射針を血管部へと導けば、容易に穿刺、採血することができる。 Then the needle while observing the blood vessel image if Michibike to blood vessels, can be easily punctured, bled.
【0014】 [0014]
実際の血管像はLEDの放射光強度、CCDカメラレンズの絞り、当該CCDの感度およびゲインに加えて、図5に示す直接反射光遮光装置301の直接光遮光領域501の長さを適切に設定することで良好なものを得ることができる。 Actual blood vessel image is emitted light intensity of the LED, the diaphragm of the CCD camera lens, in addition to the sensitivity and gain of the CCD, properly set directly length of the light shielding region 501 of the direct reflection light shielding device 301 shown in FIG. 5 what is good to be able to obtain. 特にこの直接光遮光領域長は上でも述べたように、皮膚表面で直接反射する光と一旦体内に浸透するものの皮膚表面直下の血管下まで到達せずに反射し、再度体外へと放射される光を遮蔽して、皮膚表面直下の血管下まで到達してから再度体外へと出てくる光は遮蔽しないように設定すれば良い。 In particular, as the direct light shielding region length mentioned above, reflected not reach the vessel under just below the skin surface of which once permeated into the body with the light reflected directly on the skin surface, is radiated again to the outside shields the light, the light coming out again to the outside from the reach under the vessel just below the skin surface may be set so as not to block. これらの直接反射光等の遮蔽すべき光は、直接反射光遮光装置における直接光遮光領域501を含む皮膚と接する面(LEDの貫通穴を除く)にLEDが放射する光を吸収するようなフィルタ膜を貼っておけばより確実に除去することができる。 Light to be shielded, such as those of the direct reflection light filter such as LED on the surface in contact with the skin (excluding the through hole of the LED) absorbs light radiation including direct light shielding area 501 in the direct reflected light shading device it can be more reliably removed if put the film.
【0015】 [0015]
【発明の実施の形態】 DETAILED DESCRIPTION OF THE INVENTION
図6には本発明の実施形態の一例を示す。 The Figure 6 shows an example embodiment of the present invention. 図4と同様にLED102を取り付けた直接反射光遮光装置301をヒトの前腕部101に固定バンド601により取り付け、当該LEDを照射したときにCCDカメラ104によって捉えられる血管像をモニタ105に映し出す。 Directly reflected light shading device 301 similarly fitted with LED102 and 4 Utsushidasu on the monitor 105 the blood vessel image captured by the CCD camera 104 when irradiated mounted, the LED by a fixing band 601 to the forearm 101 of the human. 図示はしていないが、より鮮明な血管像を得るためにCCDカメラ104により得られた画像をソフトウエア的あるいはハードウエア的に処理してからモニタ105上に表示しても良い。 Although not shown, it may display an image obtained by the CCD camera 104 in order to obtain a clearer blood vessel image from the processing software manner or hardware manner on the monitor 105. これにより血管位置を確認しながら採血用の注射器602を血管近傍に導き、注射針603を皮膚に穿刺し血管内に到達させ採血を行う。 Thus the syringe 602 for blood while confirming the vessel position leads to blood vessel near the injection needle 603 to reach the puncture and the blood vessels in the skin perform blood sampling.
【0016】 [0016]
【実施例】 【Example】
〔第一の実施例〕 [First embodiment]
図6に示した直接反射光遮光装置を用いた血管観察装置によりヒトの前腕内側の静脈血管を観察しながら注射針を当該血管に導き採血することを試みた。 The injection needle while observing the inside forearm of the veins of a human attempted to blood lead to the vessel by a blood vessel observation apparatus using a direct reflection light shielding apparatus shown in FIG. まず、LEDとしては放射中心波長850nm、半値幅40nmの近赤外光を放射するものを用い、また図示はしていないがCCDカメラのレンズ前に800nm以下の波長の光をカットし、それ以上の波長の光を透過させるフィルタを取り付けた。 First, the LED emission center wavelength of 850 nm, using the one that emits near-infrared light of the half-value width 40 nm, also by cutting off light of wavelengths less than 800nm ​​prior lenses Although not shown CCD camera, more fitted with a filter that transmits light having a wavelength of. このような波長のLEDを選択した理由は、まず上でも述べたように700から1200nm程度の波長の光は体内を透過しやすいこと、通常の安価なCCD素子は500から600nm程度の波長に最も高い感度を有し、波長の増加に伴い感度が減少していくためなどである。 Such wavelength LED was chosen because of, first light having a wavelength of about 1200nm from 700 as mentioned above may be easily transmitted through the body, usually inexpensive CCD elements most wavelengths of about 600nm from 500 It has high sensitivity, and the like for sensitivity with increasing wavelength decreases. またカメラにフィルターを取り付けることによって、室内の蛍光灯下においても可視光の影響を受けることなく血管観察することが可能となり、特に観察部位周辺を暗くする必要が無くなる。 Also by attaching the filter to the camera, also it is possible to vascular observed without being affected by visible light in a room under a fluorescent lamp, it is not necessary to particularly darken the observed region surrounding.
【0017】 [0017]
このようにして血管像を図6に示すようにモニタ105に映し出し、適当な血管を標的にして注射器602の注射針603を当該血管へと皮膚を穿刺して導く。 Thus the blood vessel image reflects on the monitor 105 as shown in FIG. 6, a suitable blood vessel in the target guiding the injection needle 603 of the syringe 602 to puncture the skin to the blood vessel. このとき用いた針のサイズは23ゲージであり、このようにして血管内に針を導いてから注射器の筒内を陰圧として静脈血を筒内へと約5cc採取することができた。 In this case a needle 23 gauge size using a syringe in the cylinder from the direct the needle could be about 5cc taken into the venous blood cylinder as negative pressure in this manner within the vessel.
【0018】 [0018]
また図7に示すような注射器とLEDを取り付けた直接反射光遮光装置301を一体とした装置を用いて、同様に血管観察を行いながら採血することを試みた。 Also by using the apparatus as a whole that the syringe directly reflected light shading device 301 fitted with a LED as shown in FIG. 7, it was attempted to blood while similarly vessel observed. 同図において、直接反射光遮光装置301には当該装置の小型化のためにチップLED701(放射中心波長:860nm、半値幅:40nm)を用いており、また注射筒702とガイドレール704を介して接続されており、当該注射筒は直接反射光遮光装置を固定しているとガイドレールに沿って(図中の矢印方向に)移動することができる。 In the figure, the chip LED701 for compactness of the device directly reflected light shading device 301 (emission center wavelength: 860 nm, half-value width: 40 nm) is used. In addition via a syringe 702 and the guide rails 704 are connected, the syringe barrel along the securing directly reflected light shading device guide rails (in the arrow direction in the drawing) can be moved. またここで用いた注射針603は23ゲージのものを用いた。 The injection needle 603 used here was used 23 gauge.
【0019】 [0019]
図8(A)に示す断面図のように、図7に示した注射器とLEDを取り付けた直接反射光遮光装置を一体とした装置をヒトの前腕部の皮膚表面801に設置する。 As the sectional view shown in FIG. 8 (A), the installing the apparatus as a whole that the syringe directly reflected light shading device fitted with LED shown in FIG. 7 to the skin surface 801 of the forearm of the person. このとき注射器の先端の針603はまだ皮膚に触れないような位置にセットしておき、この状態でLED701を点灯してCCDカメラ104によって血管203の像と針603の像を捉え、図には示していないがモニタ上にこれらを示して両者の位置関係から針が血管を穿刺できるような位置に注射器とLEDを取り付けた直接反射光遮光装置一体とした装置を皮膚801上で移動させる。 In this case the syringe tip of the needle 603 keep still set at the position that does not touch the skin, captures an image of the image and the needle 603 of the vessel 203 by the CCD camera 104 and light the LED701 in this state, in FIG. It shows no but is moving the device the needle from the positional relationship between illustrates these were directly reflected light shading device integrally fitted with a syringe and LED in a position that enables puncture vessels on the monitor on the skin 801. このようにしてから同図(B)に示すように、ガイドレール704に沿って注射器を皮膚側へと押し出し、針603を標的である血管に穿刺し、血管内へと導いた後にシリンジ703を引いて注射筒702内に血液を吸引採取することができた。 As shown in this way the from FIG (B), the syringe along the guide rail 704 extrusion with the skin side, the needle 603 punctures the vessel which is the target, the syringe 703 after that led into the vessel it was possible to aspirate blood collected pulling the syringe 702.
【0020】 [0020]
従来は駆血帯を用い血管を怒張させて採血していたが、このように本発明の血管の可視化装置を用いることで駆血帯を用いることなく採血することが可能となった。 It has been conventionally bled by engorgement of blood vessels using a tourniquet, but it has become possible to blood without using tourniquet Thus by using a visualization device of the vessel of the present invention. また以上の例ではLED素子を皮膚近傍の直接反射光遮光装置内に配置して照射していたが、LED等の照明装置を皮膚の遠隔に配置し、そこから光ファイバ等で直接反射光遮光装置内へと接続して皮膚表面に光を照射しても良い。 Although also above example were irradiated with LED elements arranged in a directly reflected light shading device skin near the lighting device such as an LED is disposed remotely of the skin, the directly reflected light shaded by the optical fiber or the like from there connected to the apparatus may be irradiated with light on the skin surface.
【0021】 [0021]
〔第二の実施例〕 [Second embodiment]
図9に示すようなチップ状の血液分析装置上に無痛針901(外径:100μm、内径:60μm)を介して血液を導入することを試みた。 Painless needle 901 into chips of the blood analyzer on as shown in FIG. 9 (outer diameter: 100 [mu] m, inner diameter: 60 [mu] m) was via an attempt to introduce the blood. 当該チップは2枚のポリカーボネート基板を張り合わせ構成されており、その中には血液の流路902、血液中のナトリウムイオン、カリウムイオン、グルコース、尿素窒素濃度を電気化学的にセンシングするセンサ電極903、およびセンサ出力の電気信号を出力する電極パッド904等から構成される。 The chip is composed bonding two polycarbonate substrates, the blood flow channel 902 therein, sodium ions in the blood, potassium ions, glucose, sensor electrodes 903 electrochemically sensing the urea nitrogen concentration, and it consists of the electrode pads 904 or the like for outputting an electric signal of the sensor output. チップサイズは2cm角である。 Chip size is 2cm angle.
【0022】 [0022]
次に図10(A)に示すようにスライダ1001にチップ1002を載せて、これをホルダ本体1003にはめ込み、このホルダ本体と一体となっているシリンダ1004内にチップ先端の無痛針901がセットされるようにする。 Then put the chip 1002 to the slider 1001 as shown in FIG. 10 (A), fitted it to the holder body 1003, painless needle 901 of the tip end to the holder body and the cylinder 1004 are integrated is set to so that. またこれまでの実施例と同様に直接反射光遮光装置301をヒトの上腕から前腕部の内側に設置して皮膚直下の血管像とともに上述のホルダにセットしたチップ先端の無痛針901との位置関係をCCDカメラ104によって捉え、図中には示していないがモニタ上でこれを確認する。 The previous examples as well as the directly reflected light shading device 301 positional relationship between the painless needle 901 of the tip end along with the blood vessel image is set to the above-mentioned holder immediately below and installed inside the forearm from human brachial skin the captured by the CCD camera 104, it is not shown to check it on the monitor in FIG. このとき皮膚に放射する光の光源には図6と同じLEDを用いている。 In this case the light of the light source emitting the skin is by using the same LED as in FIG. この両者の位置関係から、チップが搭載されている採血用ホルダの位置を調整し、無痛針を血管直上へと導きシリンダ1004を皮膚表面と接触させる。 From the positional relationship of both, to adjust the position of the blood collection holder chip is mounted, the cylinder 1004 leads to painless needle into the blood vessel directly contacted with the skin surface. その後にシリンダ内排気ホース1005を介して排気し、シリンダ1004内を減圧とすると皮膚はシリンダ1004に吸い付くとともにシリンダ内へと撓む。 Then evacuated through the cylinder exhaust hose 1005, skin when in the cylinder 1004 and a vacuum deflects into the cylinder with stick cylinder 1004. すると無痛針901が皮膚を穿刺して自動的に体内へと侵入する。 Then painless needle 901 penetrates into automatically body to puncture the skin. このとき無痛針が血管まで到達していれば、採血用吸引ホース1006を介してチップ内流路を減圧とし、血管から血液をチップ内へと導くことができる。 If this time has reached painless needle until blood vessel, the chip flow path to the vacuum through the blood suction hose 1006, blood can be guided into the chip from the vessel. もし血管まで針が到達していなければ同図(B)に示すようにスライダ1001を皮膚側へと押し、スポンジ1007を撓ませながら無痛針901をより深く体内へと導き血管まで到達させた後に上述と同様にして血液をチップ上に導く。 If the slider 1001 as shown in unless the needle until blood vessels have reached the figure (B) pushed into the skin side, after it allowed to reach a blood vessel leads to deeper body painless needle 901 while bending the sponge 1007 in the same manner as described above guides the blood on the chip.
【0023】 [0023]
以上のような手順により採血を試みたところチップ上に約4μlの血液を導入することができた。 It was possible to introduce about 4μl of the blood on the chip was attempted bled by the above procedure. またこのようなチップ状の血液分析装置に血液を血管から導入する際には、そのチップサイズが比較的小さくまた針の長さが通常の注射法における採血針よりも短いために、CCDカメラで無痛針および血管像を観察する空間的余裕がない場合がある。 Also when introducing blood from the blood vessel in such a chip-shaped blood analysis device, for shorter than blood collecting needle length of the chip size is relatively small also needle in a conventional injection method, a CCD camera there may be no space enough to observe the painless needle and the blood vessel image. またモニタに映し出される血管像は暗いので、その上に針が重なると、針が明瞭に確認できず、血管像と針の位置関係が確認できないことがある。 Since dark blood vessel image to be displayed on the monitor, the needle overlying the needle can not be clearly confirmed, it is the positional relationship of the blood vessel image and the needle can not be confirmed. このような場合、図11に示すようにシリンダ104にチップLED701を取り付けて、これを点灯して無痛針901に光を照射して針が明瞭に見えるようにする。 In this case, by attaching the chip LED701 the cylinder 104 as shown in FIG. 11, which is irradiated with light to painless needle 901 lit needle to appear clearly. またこのようなチップLEDの代わりに光ファイバを用い、光を導いて来て針に照射してもよい。 The used optical fiber in place of such a chip LED, may come guided light is irradiated to the needle. さらに血管像と針の位置関係を観察するためにCCDカメラ自体は遠隔に設置しておき、そこから数mm径程度の大きさのファイバスコープ1101を皮膚近傍まで持って行き、これらの像を観察してもよい。 The CCD camera itself for further observing the positional relationship between the blood vessel image and the needle Leave remotely located, the number mm diameter of approximately the size of the fiberscope 1101 therefrom bring to near the skin, observing these images it may be.
【0024】 [0024]
また図12には直接反射光遮光装置301をホルダ本体1003に取り付けた場合について示している。 Also shown in FIG. 12 shows a case fitted directly reflected light shading device 301 to the holder body 1003. またこれに加えてファイバスコープ1101もホルダ本体に取り付け血管像と針の位置関係を観察できるようになっている。 The fiberscope 1101 in addition to also become possible to observe the positional relationship between the blood vessel image and the needle attached to the holder body. シリンダ1004に取り付けてある針照明用のチップLED701は針の見え具合から放射強度を調節すればよい。 Chip LED701 for needle illumination that is attached to the cylinder 1004 may be adjusted radiation intensity from the needle of the appearance states. このようにして血管像を見ながらホルダの位置を血管上に針が位置するように設置した後に、上で述べた手順で採血を行ったところ、チップ上に約4μlの血液を導くことができた。 Such a position of the holder while watching the blood vessel image in the after installation such that the needle is located on the vessel, when blood was collected in accordance with the procedure described above, can be derived about 4μl of the blood on the chip It was.
【0025】 [0025]
次に図13には無痛針901の周りを蔽っているシリンダ1004の先端が斜めにカットしてある場合について示している。 Then in FIG. 13 shows a case where the tip of cylinder 1004 covering around painless needle 901 are cut obliquely. この場合は図10とは異なり無痛針が皮膚表面に対して垂直に刺さるのではなく、斜めに刺さるという違いがある。 In this case, instead of sticking to the perpendicular to differ painless needle skin surface and 10 is the difference that stuck diagonally. ここではカット角を45°とし、これまでと同様な手順で血管像と針の位置関係を確認して針が血管に刺さるような位置に血管を設置してから採血を行った。 Here, the 45 ° cut angles were bled vessel after installation in a position so that the needle check the positional relationship between the blood vessel image and the needle pierces the blood vessel by the same procedure as before. この結果約4μlの血液をチップ上の流路に導くことができた。 The results about 4μl of the blood could lead to the flow path on the chip. またこのように針を皮膚表面に対し斜めに穿刺する場合においても、垂直に穿刺した場合と同様に直接反射光遮光装置301をホルダ本体1003に取り付けても良い。 Or may be mounted in this way when the needle punctures oblique to the skin surface is also directly reflected light shading device 301 as if it were vertically pierced into the holder main body 1003. この場合、図7に示した注射器と直接反射光遮光装置を一体とした場合と同様にホルダを直接反射光遮光装置に対して可動としても良い。 In this case, it may be movable with respect to the directly reflected light shading device holder as in the case of an integral syringe and the directly reflected light shading device shown in FIG. さらに図13においてCCD104の代わりにファイバスコープ等で血管像と針を観察しても良く、やはりこのファイバスコープをホルダ本体と一体化して装置をコンパクトにしても良い。 Further it may be observed blood vessel image and the needle fiberscope or the like instead of CCD104 13, again may be the fiberscope compactly device integral with the holder body.
【0026】 [0026]
【発明の効果】 【Effect of the invention】
以上説明したとおり、通常の注射法により採血を行う場合に本発明の血管可視化方法ならびに装置を用いることで、従来のように駆血帯を用いることなく血管位置を確認し、確実に採血針を血管に導き、採血を行うことが可能となった。 As described above, by using the blood vessel visualization method and apparatus of the present invention when performing bled by conventional injection method, the position of the blood vessel was confirmed without using a tourniquet as in the prior art, reliably collecting needle led to a blood vessel, it has become possible to perform the blood collection. これにより被採血者に駆血帯装着時の肉体的な苦痛を及ぼすことなく採血できる。 This allows blood collection without exerting the physical pain of the tourniquet when mounted to the blood donor. また無痛針を装備したチップ血液分析装置上にも、当該無痛針の位置と血管の位置を確認しながら採血を行うことで、より確実に採血を行うことができるようになった。 Further also on the chip blood analyzer equipped with a painless needle, by collecting blood while checking the position of the blood vessel of the painless needle, it can now be performed more reliably blood. したがって、家庭で各人が本発明により簡単に採血を行い、当該血液の分析を行うことで、健康管理ができる。 Thus, each person at home performs easily bled by the present invention, by performing the analysis of the blood, it is health care.
【図面の簡単な説明】 BRIEF DESCRIPTION OF THE DRAWINGS
【図1】光反射法による血管像可視化装置を説明する図である。 1 is a diagram for explaining the blood vessel image visualization device according to light reflection method.
【図2】光を人体に投射したときの体内での光の伝播の様子を説明する図である。 2 is a diagram illustrating a state of propagation of light in the body when the projecting light to the human body.
【図3】本発明の直接反射光遮光装置の一例を説明する図である。 Is a diagram illustrating an example of the direct reflection light shielding device of the present invention; FIG.
【図4】本発明の直接反射光遮光装置を用いヒトの血管像を観察したときの様子を示す図である。 4 is a diagram showing a state of using direct reflected light shading device when observed blood vessel image of the person of the present invention.
【図5】本発明の直接反射光遮光装置の側面図を示したものである。 [5] shows a side view of the directly reflected light shielding device of the present invention.
【図6】本発明の直接反射光遮光装置を用いヒトの血管像を観察しながら注射法により採血を行う様子を示す図である。 It is a diagram showing a state of performing bled by injection method while observing the blood vessel image of the person using the direct reflection light shielding device of the present invention; FIG.
【図7】本発明の直接反射光遮光装置と従来の注射器を一体化した装置を示す図である。 7 is a diagram showing a device that integrates directly reflected light shading device and a conventional syringe of the present invention.
【図8】図7で示した装置を用いて採血を行う様子を示す図である。 It is a diagram showing a state of performing blood using the apparatus illustrated in FIG. 8 Fig.
【図9】チップ状血液分析装置を示す図である【図10】図9に示したチップ状血液分析装置上に本発明の直接反射光遮光装置を用い、血液を導入する手順を説明する図である。 [9] The direct reflection light shielding device of the present invention used in the chip-shaped blood analysis shows a device [10] on a chip-shaped blood analysis apparatus shown in FIG. 9, a procedure for introducing a blood drawing it is.
【図11】図9に示したチップ状血液分析装置上に本発明の直接反射光遮光装置を用い、血液を導入する様子を説明する図である。 [11] The direct reflection light shielding device of the present invention used on a chip-shaped blood analysis apparatus shown in FIG. 9 is a diagram for describing a manner of introducing the blood.
【図12】図9に示したチップ状血液分析装置上に本発明の直接反射光遮光装置を用い、血液を導入する様子を説明する図である。 [12] The direct reflection light shielding device of the present invention using the chip-shaped blood analysis apparatus shown in Figure 9, is a view describing a manner of introducing the blood.
【図13】図9に示したチップ状血液分析装置上に本発明の直接反射光遮光装置を用い、血液を導入する様子を説明する図である。 [13] The direct reflection light shielding device of the present invention used on a chip-shaped blood analysis apparatus shown in FIG. 9 is a diagram for describing a manner of introducing the blood.
【符号の説明】 DESCRIPTION OF SYMBOLS
101 ヒトの前腕部102 LED 101 human forearm 102 LED of
103 電源104 CCDカメラ105 モニタ106 腕の像201 皮膚202 骨203 血管204 直接反射光205 内部浸透後反射してきた光301 直接反射光遮光装置302 貫通穴401 血管下まで到達せず反射する光402 血管像403 直接反射光遮光装置の像501 直接光遮蔽領域601 固定バンド602 注射器603 注射針701 チップLED 103 power supply 104 CCD camera 105 monitors 106 the arm of the image 201 skin 202 bone 203 vessel 204 directly reflected light 205 reflected light 402 vessel not reach it reflected becoming light 301 directly reflected light shading device 302 through hole 401 vessels under post interpenetrating image 403 directly reflected light shading device image 501 direct light shielded region 601 fixing band 602 syringe 603 needle 701 chip LED of
702 注射筒703 シリンジ704 ガイドレール801 皮膚表面901 無痛針902 流路903 センサ電極904 電極パッド1001 スライダ1002 チップ1003 ホルダ本体1004 シリンダ1005 シリンダ内排気ホース1006 採血用吸引ホース1007 スポンジ1101 ファイバスコープ 702 syringe 703 syringe 704 guide rail 801 skin surface 901 painless needle 902 passage 903 sensor electrode 904 electrode pad 1001 slider 1002 chip 1003 holder body 1004 cylinder 1005 suction hose 1007 sponge 1101 fiberscope for cylinder exhaust hose 1006 blood collection

Claims (18)

  1. 少なくとも600から1200nmの波長成分を含み、かつ少なくとも一つの光源から発せられた光を人体に照射したときの反射光から照射した部位近傍の皮膚直下の血管像を得る血管可視化方法であって、特に反射してきた光の内、皮膚表面での直接反射光および人体に侵入するものの皮膚直下の血管まで到達せず反射して再び体外へと出射してくる光を排除し、人体に侵入して皮膚直下の血管より深部まで到達してから反射して再び体外に出射してくる光の強度の空間分布を撮像素子によって捉え、これを表示装置に表示することを特徴とする血管可視化方法。 Includes 1200nm wavelength component from at least 600, and a blood vessel visualization method for obtaining images of blood vessels just under the skin near the site being irradiated with light emitted from at least one light source from the reflected light when irradiated in the human body, in particular of the light reflected, the exclusion of light coming emitted to reflected again extracorporeal not reach blood vessels just below the skin of those entering directly reflected light and the human body at the skin surface and penetrate the human skin vascular visualization method characterized in that from the vessel immediately under deep captured by the image sensor the spatial distribution of the intensity of light coming emitted again outside reflected after reaching, and displays this on the display device.
  2. 少なくとも600から1200nmの波長成分を含む光を放射する少なくとも一つの光源を構成要素として含み、当該光源から放射される波長の光をほとんど透過しないような材料で少なくとも表面の一部が構成される直接反射光遮光装置であって、特に当該直接反射光遮光装置を構成する一つの面を人体の皮膚表面と接触させ、光源から光を放射したときにその大部分は皮膚表面に至るようにし、このとき皮膚表面から直接反射する光および人体に侵入するものの皮膚直下の血管まで到達せず反射して再び体外へと出射してくる光の少なくとも一部を直接反射光遮光装置の皮膚と接している面、あるいは直接反射光遮光装置と皮膚に囲まれる空間によって遮り、再び体外に放射されることの無いようにし、一方光源から放射され皮膚表面を Comprising at least one light source emits light having a 1200nm wavelength component from at least 600 as a component, at least part of the surface directly formed by the material such as hardly transmit light of a wavelength emitted from the light source a reflected light shading device, in particular by contacting one of the surfaces constituting the direct reflection light shading device with human skin surface, the majority of when light is emitted from the light source to reach the skin surface, this is in contact with the skin of the direct reflection light shielding apparatus at least part of the light coming emitted to again reflected without reaching outside to blood vessels just under the skin of those entering the light and the body directly reflected from the skin surface when surface, or obstruct the space surrounded by the directly reflected light shading device and the skin, so as never to be re-radiated to the outside, whereas the emitted skin surface from the light source て人体に侵入し、皮膚直下の血管より深部まで到達してから反射して再び体外に出射してくる光の大部分は遮ることなく体外に放射させることを特徴とする直接反射光遮光装置。 Te invade the human body, the reflected light shading device directly for causing emitted outside the body without the majority of the light coming emitted again outside reflected after reaching from deep vessel intercepts just below the skin.
  3. 少なくとも600から1200nmの波長成分を含む光を放射する光源から、当該光源から放射される波長の光をほとんど透過しないような材料で少なくとも表面一部が構成される直接反射光遮光装置に光を導き、当該直接反射光遮光装置を構成する一つの面を人体の皮膚表面と接触させたときに、光源から放射された光の大部分は皮膚表面に至るようにし、このとき皮膚表面から直接反射する光および人体に侵入するものの皮膚直下の血管まで到達せず反射して再び体外へと出射してくる光の少なくとも一部を直接反射光遮光装置の皮膚と接している面、あるいは直接反射光遮光装置と皮膚に囲まれる空間によって遮り、再び体外に放射されることの無いようにし、一方光源から放射され皮膚表面を経て人体に侵入し、皮膚直下の血管より From a light source that emits light including a 1200nm wavelength component from at least 600 guides the light to at least the surface portion is directly reflected light shading device constructed of a material that hardly transmits light of a wavelength emitted from the light source , when one of the surfaces constituting the direct reflected light shading device was contacted with human skin surface, most of the light emitted from the light source to reach the skin surface, directly reflected from the time the skin surface surfaces in contact with the skin of at least a portion of the direct reflection light shading device light coming emitted to again reflected without reaching outside to blood vessels just under the skin of those entering the light and the body or directly reflected light shielding, intercept the space surrounded by apparatus and the skin, so as never to be re-radiated to the outside, whereas emitted from a light source enters the human body through the skin surface, from blood vessels just under the skin 部まで到達してから反射して再び体外に出射してくる光の大部分は遮ることなく体外に放射させることを特徴とする直接反射光遮光装置。 The directly reflected light shading device, characterized in that the majority of the light coming emitted again outside reflected from reach the parts are to be radiated to the outside without interrupting.
  4. 前記請求項3において、特に光源から直接反射光遮光装置へと光を導くために光ファイバを用いることを特徴とする直接反射光遮光装置。 The according to claim 3, in particular directly reflected light shading device which is characterized by using an optical fiber for guiding light to the direct reflection light shielding device from the light source.
  5. 前記請求項2または3に記載の直接反射光遮光装置の皮膚と接する面の少なくとも一部は、光源から放射される波長の光を吸収するような材料で表面が覆われていることを特徴とする直接反射光遮光装置。 Claim at least a portion of the surface in contact with the skin of the direct reflection light shielding device according to 2 or 3, and characterized in that the surface material that absorbs light of wavelengths emitted are covered from the light source the directly reflected light shielding device for.
  6. 前記請求項2または3に記載の直接反射光遮光装置により、体外へと反射放射してきた光の強度の空間分布を撮像素子によって捉え、これを表示装置に表示することで皮下の血管像を得ることを特徴とする血管可視化装置。 The direct reflection light shielding device according to claim 2 or 3, captured by the image sensor the spatial distribution of the intensity of light reflected radiated to the outside of the body, to obtain images of blood vessels subcutaneous by displaying this on the display device vascular visualization device, characterized in that.
  7. 前記請求項6に記載の撮像素子に入射する光の波長範囲を透過し、かつ少なくとも当該波長範囲よりも短波長側の光を吸収するようなフィルタを当該撮像素子の光の入射する部位の前に配置することを特徴とする血管可視化装置。 Previous site the transmitted through the wavelength range of light incident on the imaging device according to claim 6, and a filter to absorb light even in the short wavelength side of at least the wavelength range incident light of the imaging device vascular visualization device, characterized in that arranged in.
  8. 前記請求項6に記載の撮像素子に入射する光の波長範囲を透過し、かつ当該波長範囲以外の光を吸収するようなフィルタを当該撮像素子の光の入射する部位の前に配置することを特徴とする血管可視化装置。 Said transmitted through the wavelength range of light incident on the imaging device according to claim 6, and to place a filter to absorb light other than the wavelength range in front of the site where the incident light of the imaging device vascular visualization apparatus characterized.
  9. 前記請求項1に記載の血管可視化方法により血管位置を確認しながら注射器と一体となった採血針の穿刺位置を決定し、針を皮下の血管へと導き、採血を行うことを特徴とする採血方法。 Blood wherein the blood vessel visualization method according to claim 1 to determine the puncture location of the blood collection needle was a syringe integrally while checking the blood vessel position, the needle guidance to vessels subcutaneous, and performing blood sampling Method.
  10. 前記請求項2または3に記載の直接反射光遮光装置と採血針を装備した注射器が一体となっていることを特徴とする採血装置。 Blood collection apparatus syringe equipped with a blood collection needle and the directly reflected light shielding device according to claim 2 or 3, characterized in that together.
  11. 前記請求項10に記載の注射器が直接反射光遮光装置を固定したときに当該直接反射光遮光装置に対して可動であることを特徴とする採血装置。 Blood collection device which is a movable relative to the direct reflected light shading device when syringe according to claim 10 is fixed directly reflected light shading device.
  12. 前記請求項1に記載の血管可視化方法により血管位置を確認しながら採血針の穿刺位置を決定し、針を皮下の血管へと導き、当該採血針と一体となった血液分析装置上に血液を導くことを特徴とする採血方法。 Wherein determining a puncture location of the blood collection needle while checking the position of the blood vessel by a blood vessel visualization method according to claim 1, needle leads to blood vessel subcutaneously, the blood collection needle and together form the blood analyzer on the blood blood wherein the directing.
  13. 前記請求項9または12に記載の採血方法において、主に採血針に光を照射し、血管と針の位置関係を明瞭にすることを特徴とする採血方法。 Blood collection method characterized in that said at blood collection method according to claim 9 or 12, mainly applies light to the blood collection needle, to clarify the positional relationship between the blood vessel and the needle.
  14. 前記請求項6に記載の血管可視化装置と、採血針と一体となった血液分析装置を少なくとも構成要素と含むことを特徴とする採血装置。 Wherein the blood vessel visualization device according to claim 6, blood collection device, characterized in that the blood analyzer becomes blood collection needle integrally including at least a component.
  15. 前記請求項14において、採血針を照射する光源を構成要素として含むことを特徴とする採血装置。 The according to claim 14, blood collection apparatus comprising a light source for irradiating blood collecting needle as a component.
  16. 前記請求項15において、採血針を照射する光源は、採血針と一体となった血液分析装置を支持するホルダと一体となっていることを特徴とする採血装置。 In claim 15, a light source for irradiating a blood collection needle, the blood collection device, characterized in that it is a holder integrally supporting the blood analyzer became blood collection needle integrally.
  17. 前記請求項14において、血管可視化装置を構成する直接反射光遮光装置は、特に採血針と一体となった血液分析装置を支持するホルダと一体となっていることを特徴とする採血装置。 The according to claim 14, the directly reflected light shading device that form vascular visualization device, blood collecting apparatus being characterized in that it is a holder integrally supporting the blood analyzer in particular a blood collection needle and integrally.
  18. 前記請求項14において、血管可視化装置を構成する撮像素子もしくは撮像素子に光を導く光ファイバの一端が、特に採血針と一体となった血液分析装置を支持するホルダと一体となっていることを特徴とする採血装置。 In claim 14, the one end of the optical fiber for guiding light to the image pickup device or image pickup element form vascular visualization device has a holder integrally supporting the blood analyzer in particular a blood collection needle integral blood collection device according to claim.
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