JP2004168768A5 - - Google Patents
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- Publication number
- JP2004168768A5 JP2004168768A5 JP2003369875A JP2003369875A JP2004168768A5 JP 2004168768 A5 JP2004168768 A5 JP 2004168768A5 JP 2003369875 A JP2003369875 A JP 2003369875A JP 2003369875 A JP2003369875 A JP 2003369875A JP 2004168768 A5 JP2004168768 A5 JP 2004168768A5
- Authority
- JP
- Japan
- Prior art keywords
- enoyl
- pyrazol
- fluorophenyl
- prop
- benzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NSVIDGDZEVEYKX-XNTDXEJSSA-N (e)-n-[4-(diethoxyphosphorylmethyl)phenyl]-3-[5-(4-fluorophenyl)-1-methylpyrazol-4-yl]prop-2-enamide Chemical compound C1=CC(CP(=O)(OCC)OCC)=CC=C1NC(=O)\C=C\C1=C(C=2C=CC(F)=CC=2)N(C)N=C1 NSVIDGDZEVEYKX-XNTDXEJSSA-N 0.000 claims 1
- IIRVGTWONXBBAW-UHFFFAOYSA-M disodium;dioxido(oxo)phosphanium Chemical compound [Na+].[Na+].[O-][P+]([O-])=O IIRVGTWONXBBAW-UHFFFAOYSA-M 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003369875A JP4145230B2 (ja) | 2002-11-01 | 2003-10-30 | 神経障害の予防・治療剤 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002320153 | 2002-11-01 | ||
| JP2003369875A JP4145230B2 (ja) | 2002-11-01 | 2003-10-30 | 神経障害の予防・治療剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008128851A Division JP2008231115A (ja) | 2002-11-01 | 2008-05-15 | 神経障害の予防・治療剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004168768A JP2004168768A (ja) | 2004-06-17 |
| JP2004168768A5 true JP2004168768A5 (cg-RX-API-DMAC7.html) | 2008-07-03 |
| JP4145230B2 JP4145230B2 (ja) | 2008-09-03 |
Family
ID=32715932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003369875A Expired - Fee Related JP4145230B2 (ja) | 2002-11-01 | 2003-10-30 | 神経障害の予防・治療剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4145230B2 (cg-RX-API-DMAC7.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG151336A1 (en) * | 2004-04-01 | 2009-04-30 | Aventis Pharma Inc | 1,3,4-oxadiazol-2-ones as ppar delta |
| DE602005027677D1 (de) * | 2004-04-01 | 2011-06-09 | Aventis Pharma Inc | 1,3,4-oxadiazol-2-one als ppar-delta-modulatoren und deren verwendung |
| JP5137572B2 (ja) * | 2004-06-24 | 2013-02-06 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 第四級塩であるｃｃｒ２アンタゴニスト |
| US20100029724A1 (en) * | 2006-07-19 | 2010-02-04 | Takeda Pharmaceutical Company Limited | Screening method |
| EP1939180A1 (en) * | 2006-12-20 | 2008-07-02 | sanofi-aventis | Heteroarylacrylamides and their use as pharmaceuticals for the stimulation of the expression of endothelial NO synthase |
| UA115532C2 (uk) | 2011-07-29 | 2017-11-27 | Каріофарм Терапеутікс, Інк. | Модулятори нуклеарного транспорту, що містять гідразид, і їхнє застосування |
| WO2013019561A1 (en) * | 2011-07-29 | 2013-02-07 | Karyopharm Therapeutics, Inc. | Nuclear transport modulators and uses thereof |
| KR102163377B1 (ko) | 2012-05-09 | 2020-10-08 | 바이오젠 엠에이 인코포레이티드 | 핵 수송 조절인자 및 이의 용도 |
| EP2968278B8 (en) | 2013-03-15 | 2019-05-22 | Karyopharm Therapeutics Inc. | Methods of promoting wound healing using crm1 inhibitors |
| AU2014284168B2 (en) | 2013-06-21 | 2018-10-25 | Karyopharm Therapeutics Inc. | Nuclear transport modulators and uses thereof |
| WO2016025904A1 (en) | 2014-08-15 | 2016-02-18 | Karyopharm Therapeutics Inc. | Polymorphs of selinexor |
| US10526295B2 (en) | 2015-12-31 | 2020-01-07 | Karyopharm Therapeutics Inc. | Nuclear transport modulators and uses thereof |
| EP3397634A1 (en) | 2015-12-31 | 2018-11-07 | Karyopharm Therapeutics, Inc. | Nuclear transport modulators and uses thereof |
| US11602530B2 (en) | 2016-11-28 | 2023-03-14 | Biogen Ma Inc. | CRM1 inhibitors for treating epilepsy |
| GB201901559D0 (en) * | 2019-02-05 | 2019-03-27 | Syngenta Crop Protection Ag | Herbicidal compositions |
-
2003
- 2003-10-30 JP JP2003369875A patent/JP4145230B2/ja not_active Expired - Fee Related
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