JP2003250911A - Manifold - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a manifold in which a quantity of objects to be discarded can be reduced, complicated duct switching operation is not required and a quantity of air to be stagnated within ducts can be reduced, as the manifold for making possible the dosage of a liquid medicine within a prefilled syringe and the other liquid medicine. <P>SOLUTION: In the manifold having two inflow ports 4 and 6 and one outflow port 8 respectively communicated with these inflow ports, a duct needle 18 with which a stopper 72 of a prefilled syringe 70 is pierced is secured to one of the inflow ports. Further, a confluence part 14 of ducts and the outflow port communicates with each other all the time, and a duct switching mechanism 20 is provided for opening one of ducts 10 and 12 between the two inflow ports and the confluence part and closing the other duct. <P>COPYRIGHT: (C)2003,JPO

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a multi-branch flow tube used when administering a drug solution into a body by using a drug solution-filled syringe (prefilled syringe) prefilled with the drug solution.

[0002]

2. Description of the Related Art Conventionally, as a three-way stopcock used when a drug solution is administered into the body using a prefilled syringe, there is one shown in Japanese Patent No. 2764432. This three-way stopcock has two systems of liquid inlets and one system of liquid outlet, and is a three-way stopcock that selectively controls the flow of liquid to one system or two systems. Is a cartridge-type injection syringe (prefilled syringe) with a rubber plug pre-enclosed therein, and an injection needle for piercing the rubber plug is projected while communicating with the tip. When this three-way stopcock is used, it is possible to administer the drug solution in the prefilled syringe and another drug solution (for example, physiological saline) into the body.

[0003]

[Patent Document 1] Japanese Patent No. 2764432

[0004]

However, the three-way stopcock of the above-mentioned Japanese Patent No. 2764432 has the following (a) to (c).
It had the problems shown in.

(A) The three-way stopcock of Japanese Patent No. 2764432 has a "branching cylinder" having three branch pipes and a branch pipe having a flow path corresponding to the branch pipes of the branch cylinder. It has a "rotating plug" that is rotatably arranged in the body, and a "cock" that is attached to the rotating plug to switch the flow path, and the needle and the three-way stopcock are integrated. Therefore, the number of members is large, and the mass and volume are large. Therefore, the mass and volume of the waste become large. Moreover, since the needle is integrated, the entire three-way stopcock becomes a waste containing metal. Furthermore, since the prefilled syringe is used for radiopharmaceuticals, in this case the waste is all metal-containing radioactive waste.

[0006] Syringes, injection needles, etc. after handling radiopharmaceuticals are to be disposed of as radioactive wastes, and are classified as incombustibles, combustibles, flame retardants, etc. depending on the material of the wastes. Then, it will be collected and disposed of by a radioactive waste treatment company such as the Japan Isotope Association.

(B) The three-way stopcock of Japanese Patent No. 2764432 was determined by rotating the cock portion when the flow passage of the rotary plug body was made to correspond to the branch pipe of the branch cylinder for switching the flow passage. Since it needs to be adjusted to the position, it requires detailed operations with both hands, and mistakes are likely to occur.

(C) In the three-way stopcock of Japanese Patent No. 2764432, since the flow passage is provided in the rotary stopper body, the amount of air accumulated in the flow passage is large, and the air bleeding when administering the liquid medicine is troublesome. is there.

The present invention has been made in view of the above-mentioned circumstances, and is used when a drug solution is administered into the body using a prefilled syringe, and the drug solution in the prefilled syringe and another drug solution are administered into the body. This is a multi-branch flow tube that enables the reduction of the amount of waste, especially radioactive waste, and also does not require a fine flow path switching operation with both hands to rotate the cock part. An object of the present invention is to provide a multi-branch flow channel pipe capable of reducing the amount of air accumulated in the flow channel.

[0010]

In order to achieve the above-mentioned object, the present invention comprises two or more inflow ports and one outflow port which communicates with the two or more inflow ports via respective flow paths. A multi-branch flow pipe having flow paths from the two or more inflow ports that meet at a merging portion, and the combined flow paths reach the outflow port. A flow path needle for piercing the stopper of the prefilled syringe is attached to a part of the inflow port, and the confluence section and the outflow port are always in communication with each other, and
Provided is a multi-branch flow path pipe, which is provided with a flow path switching mechanism that opens any one of the flow paths between the two or more inflow ports and the merging portion and closes the other.

When the number of inflow ports is two, the multi-branch flow pipe of the present invention is used as follows, for example. First, with the flow path switching mechanism closing the flow path between the inflow port to which the flow path needle is attached and the merging portion, the first drug solution (for example, physiological saline) is introduced into the inflow port where the flow path needle is not attached. While connecting a syringe filled with water), an injection needle is connected to the outflow port, and the above-mentioned injection device is used to fill the flow path between the inflow port of the first drug solution and the tip of the injection needle with the first drug solution, The recipient is punctured with an injection needle. Next, a prefilled syringe filled with a second drug solution (for example, a radiopharmaceutical) is connected to the inflow port equipped with the flow path needle, and the flow path between the inflow port equipped with the flow path needle and the merging portion is connected. With the flow path switching mechanism opened, the second drug solution is administered to the recipient from the injection needle using the prefilled syringe.

Therefore, in the multi-branch flow pipe of the present invention, since the flow passages are switched without using the three-way stopcock consisting of many members, the amount of waste can be reduced. Further, since the flow passages are switched only by an easy operation such as the operation of the flow passage switching mechanism, it is not necessary to perform a fine flow passage switching operation with both hands of rotating the cock portion, and an erroneous operation can be prevented. Further, unlike the three-way stopcock, it does not have a flow passage inside the rotary stopper, so that the amount of air accumulated in the flow passage can be reduced.

In this case, in the present invention, the structure of the flow path switching mechanism is not particularly limited as long as it can open any one of the flow paths between the inlet and the merging portion and close the other. Good. Specific examples of the flow path switching mechanism include a plug-type switching cock that switches the flow path by advancing and retracting as shown in the embodiments described later.

Further, in the present invention, it is suitable that the flow path needle is removable from the inflow port to which the flow path needle is attached. As a result, the amount of waste containing metal can be reduced.

Further, in the present invention, it is preferable to have a flow path needle protecting portion surrounding the flow path needle. As a result, the effect of preventing the risk of fingertip puncture, etc. by the flow path needle, and the effect of protecting the tip of the flow path needle from the outside and the contact between the tip of the flow path needle and the outside can be obtained. be able to. Although the structure of the flow path needle protection unit can be appropriately determined, for example, a rubber that is in close contact with the flow path needle and covers the flow path needle is provided, and the needle tip pierces the rubber during use to puncture the plug of the prefilled syringe. And a cap made of plastic or the like that is attached to and detached from the inflow port in which the flow path needle is attached, and a cap that surrounds the flow path needle is provided.

[0016]

BEST MODE FOR CARRYING OUT THE INVENTION Next, embodiments of the present invention will be described with reference to the drawings, but the present invention is not limited to the following examples.

FIG. 1 is a schematic view showing an embodiment of a multi-branch flow pipe according to the present invention. The multi-branch flow pipe 2 of this example is made of metal,
It is mainly composed of a substantially Y-shaped pipe material formed of plastic, glass or the like, and has two inflow ports, that is, a first inflow port 4 and a second inflow port 6, and the two inflow ports 4 and 6 described above. And one outlet 8 that communicates with each other via a flow path.
Have and. The flow channel 10 from the first inflow port 4 and the flow channel 12 from the second inflow port 6 merge at the merging portion 14, and the merged flow channel 16 reaches the outflow port 8.

A flow path needle 18 for piercing the stopper of the prefilled syringe is detachably attached to the second inflow port 6. Further, the flow passage switching mechanism in which the merging portion 14 and the outlet 8 are always in communication with each other and one of the flow passages 10 and 12 between the two inlets 4 and 6 and the merging portion 14 is opened and the other is closed. 20 is provided near the confluence portion 14.

2 and 3 are perspective views showing an example of the flow path switching mechanism. In the flow path switching mechanism of this example, the large diameter portion 10 is provided in the flow path between the inflow port to which the flow path needle is attached and the merging portion.
2 and a small diameter portion 104 on the upstream side thereof are formed, and a large diameter portion 1
02, a plug type switching cock 106 is arranged. The plug-type switching cock 106 has a plug body 110 having a conical portion 108 at the rear end, and a slide member 112 for moving the plug body 110 forward and backward by an operation from outside the multi-branch flow pipe. A first flow path 114 and a second flow path 116 are formed.

In the flow path switching mechanism of this example, when the plug body 110 is advanced by operating the slide member 112 as shown in FIG.
The outlet of the flow path 10 between the inflow port 4 and the merging portion of the
The flow path 10 is closed and the plug body 110
Through the first flow path 114 of the second inflow port 6 and the merging portion 14
The chemical liquid flows in the flow path 12 between the and (the flow path 12 is open). On the other hand, when the plug main body 110 is retracted by operating the slide member 112 as shown in FIG. 3, the opening of the small diameter portion 104 is closed by the conical portion 108, and the gap between the second inlet 6 and the confluence portion 14 is closed. The channel 12 is closed, and the chemical solution flows through the second channel 116 of the plug body 110 to the channel 10 between the first inlet 4 and the merging portion 14 (the channel 10 is open).

FIG. 4 is a conceptual diagram showing an example of how to use the multi-branch flow pipe 2 of this example. Referring to FIGS. 1 and 4,
The multi-branch flow pipe 2 of this example is used as follows, for example. It is to be noted that the reference numerals ~ in Fig. 4 correspond to the following reference numerals ~.

Second inflow port 6 to which a flow path needle 18 is attached
The syringe 50 in which the first inflow port 4 (the inflow port to which the flow path needle is not attached) is filled with physiological saline in a state where the flow path 12 between the merging portion 14 and the confluence portion 14 is closed by the flow path switching mechanism 20. And the winged needle (injection needle) 60 is connected to the outflow port 8. The plunger 52 of the syringe 50 is advanced to fill the flow path between the first inlet 4 and the tip of the winged needle 60 with saline. The winged needle 60 is punctured in the recipient. The plunger 52 of the syringe 50 is slightly retracted to secure the blood vessel (confirm whether the winged needle 60 is stuck in the blood vessel). In this case, when blood flows back into the flow channel, the blood vessel has been secured. The flow path needle 18 is punctured in the rubber stopper 72 of the prefilled syringe 70 filled with the radiopharmaceutical, and the prefilled syringe 70 is connected to the second inflow port 6. Further, the flow passage 12 between the second inlet 6 and the confluence portion 14 is connected to the flow passage switching mechanism 2
It is opened by 0. Incidentally, reference numeral 74 in the figure denotes a radiation shielding member accommodating the prefilled syringe 70. Further, the prefilled syringe 70 may be connected to the second inflow port 6 at a stage before this. The plunger 78 attached to the gasket 76 of the prefilled syringe 70 is slightly retracted, and the air in the flow path in the multi-branched flow path tube 2 is once moved into the prefilled syringe 70. The plunger 78 is advanced and the prefilled syringe 7
The radiopharmaceutical within 0 is administered to the recipient. The flow passage 12 between the second inlet 6 and the merging portion 14 is closed by the flow passage switching mechanism 20. Then, the plunger 52 of the syringe 50 is advanced, and the radiopharmaceutical remaining in the flow path is pushed out by physiological saline to administer all to the recipient (physiological saline flush). The prefilled syringe 70 is detached from the second inflow port 6.

Although the number of inflow ports is two in the above-mentioned embodiment, it may be three or more. When the number of inflow ports is three or more, a flow path needle for piercing the stopper of the prefilled syringe may be attached to at least one of them. An example in which the number of inlets is three is shown below.

An example of the multi-branch flow pipe of the present invention having three inflow ports is shown in FIGS. 5 to 7,
(A) shows a front view and (b) shows a rear view. The multi-branch flow pipe 202 of this example has three inlets, that is, the first inlet 2
04, the second inlet 206 and the third inlet 208
And one outflow port 210 that communicates with the three inflow ports 204, 206, and 208 via flow paths, respectively. The flow path 212 from the first inflow port 204, the flow path 214 from the second inflow port 206, and the flow path 216 from the third inflow port 208 meet at a merging portion 218, and the combined flow path 220 Has reached the outlet 210.

A flow path needle (not shown) for piercing the stopper of the prefilled syringe is detachably attached to one or two of the three inflow ports 204, 206 and 208. Further, the merging portion 218 and the outlet 210 are always in communication with each other, and the three inlets 204, 20
6, 212 and the flow paths 212 and 21 between the merging portion 218.
A flow path switching mechanism that opens any one of 4, 4 and 216 and closes the other is provided.

The flow path switching mechanism of this embodiment is composed of a tubular body 224 integrally formed with a multi-branch flow path tube body and a plug type switching cock 22.
6 and 6. The plug-type switching cock 226 is the tubular body 2.
A cylindrical plug body 228 slidably inserted into the inside of 24, and a slide member 230 for advancing and retracting the plug body 228 by an operation from the outside of the multi-branch flow pipe.
In the plug body 228, one flow path 23 is formed in the radial direction.
2 is formed.

In the flow path switching mechanism of this embodiment, when the plug body 228 is arranged at the center by the operation of the slide member 230 as shown in FIG. 5, the first flow inlet 204 is passed through the flow path 232 of the plug body 228. Flow path 2 between confluence section 218
The chemical solution flows into 12 (only the flow path 212 is opened). When the plug body 228 is arranged on the right side when viewed from the front by operating the slide member 230 as shown in FIG.
8 through the flow path 232 and the second inlet 206 and the merging portion 2
The chemical solution flows in the flow path 214 between the flow path 18 and 18 (only the flow path 214 is opened). When the plug body 228 is arranged on the left side when viewed from the front by operating the slide member 230 as shown in FIG. 7, the flow between the third inflow port 208 and the merging portion 218 passes through the flow path 232 of the plug body 228. The chemical solution flows into the passage 216 (only the passage 216 is opened).

Other examples of the multi-branch flow pipe of the present invention having three inflow ports are shown in FIGS. 8 to 10, (a) shows a front view and (b) shows a rear view. The multi-branch flow pipe 302 of this example has three inlets, that is, a first inlet 304, a second inlet 306, and a third inlet 30.
8 and one outflow port 310 that communicates with the three inflow ports 304, 306, and 308 via flow paths, respectively. The flow path 312 from the first inflow port 304, the flow path 314 from the second inflow port 306, and the flow path 316 from the third inflow port 308 meet at a merging portion 318, and the merged flow path 320. Has reached the outlet 310.

A flow path needle (not shown) for piercing the stopper of the prefilled syringe is detachably attached to one or two of the three inflow ports 304, 306, 308. Further, the merging portion 318 and the outlet 310 are always in communication with each other, and the three inlets 304, 30 are provided.
6, 312 and the flow paths 312 and 31 between the merging portion 318
A flow path switching mechanism that opens any one of 4, 316 and closes the other is provided.

In the flow path switching mechanism of this example, the second inlet port 3
06 and the third inflow port 308 and the large diameter portion 402 in the flow path.
And small diameter portions 404 and 406 on the upstream side (both sides) thereof are formed, and a plug type switching cock 408 is arranged on the large diameter portion 402. The plug type switching cock 408 includes a plug body 412 having conical portions 410 at both ends and a plug body 41.
2 has a slide member 414 for advancing and retracting the multi-branch flow channel pipe from the outside, and a first flow channel 416, an L-shaped second flow channel 418, and an L-shaped flow channel in the plug body 412. A letter-shaped third flow path 420 is formed. The second flow path 418 and the third flow path 420 are in communication with each other.

In the flow path switching mechanism of this example, when the plug body 412 is arranged at the center by the operation of the slide member 414 as shown in FIG. 8, the first flow path 416 of the plug body 412 is arranged.
The liquid medicine flows through the flow path 312 between the first inflow port 304 and the merging portion 318 (only the flow path 312 is opened). As shown in FIG. 9, the plug body 41 is operated by operating the slide member 414.
When 2 is arranged on the left side when viewed from the front, the outer peripheral surface of the plug body 412 blocks the flow path 312 from the first inflow port 304 and the flow path 316 from the third inflow port 308, and The chemical solution flows through the second flow path 418 of 412 to the flow path 314 between the second inflow port 306 and the merging portion 318 (only the flow path 314 is opened). As shown in FIG. 10, the plug body 41 is operated by operating the slide member 414.
When 2 is arranged on the right side when viewed from the front, the outer peripheral surface of the plug body 412 blocks the flow path 312 from the first inflow port 304 and the flow path 314 from the second inflow port 306, and The chemical solution flows through the third flow path 420 of 412 to the flow path 316 between the third inflow port 308 and the merging portion 318 (only the flow path 316 is opened).

An example of the use of the multi-branch flow pipe of the present invention having three inflow ports is load inspection. The stress test includes, for example, first administering the stress drug, then administering the radiopharmaceutical, and finally administering the physiological saline.

[0033]

As described above, according to the multi-branch flow pipe of the present invention, the amount of waste, particularly radioactive waste, can be reduced, and the cock portion can be rotated with both hands. Therefore, it is possible to prevent an erroneous operation, and to reduce the amount of air accumulated in the flow path.

[Brief description of drawings]

FIG. 1 is a schematic view showing an embodiment of a multi-branch flow pipe according to the present invention.

FIG. 2 is a perspective view showing an example of a flow path switching mechanism.

FIG. 3 is a perspective view showing an example of a flow path switching mechanism.

FIG. 4 is a conceptual diagram showing an example of how to use the multi-branch flow pipe of FIG.

FIG. 5 is a schematic view showing another embodiment of the multi-branch flow pipe according to the present invention.

6 is a schematic view showing a state in which the flow paths of the multi-branch flow path pipe of FIG. 5 are switched.

FIG. 7 is a schematic diagram showing a state in which the flow paths of the multi-branch flow path pipe of FIG. 5 are switched.

FIG. 8 is a schematic view showing still another embodiment of the multi-branch flow pipe according to the present invention.

9 is a schematic view showing a state in which the flow paths of the multi-branch flow path tube of FIG. 8 are switched.

10 is a schematic diagram showing a state in which the flow paths of the multi-branch flow path tube of FIG. 8 are switched.

[Explanation of symbols]

2 Multi-branch flow pipe 4 Inlet 6 Inlet 8 Outlet 10 channels 12 channels 14 Confluence section 16 channels 18 flow path needle 20 flow path switching mechanism 50 syringes 60 winged needle (injection needle) 70 Prefilled Syringe 72 Rubber stopper 202 Multi-branch flow pipe 204 First inlet 206 Second inlet 208 Third inlet 210 Outlet 212 channel 214 flow path 216 flow path 218 Confluence part 226 plug type switching cock 304 First inlet 306 Second inlet 308 Third inlet 310 Outlet 312 channel 314 flow path 318 Confluence Section 408 plug type switching cock

   ─────────────────────────────────────────────────── ─── Continued front page    (72) Inventor Kyoko Hieda             1-13-5 Kudankita, Chiyoda-ku, Tokyo Japan             Jiphysics Co., Ltd. Tokyo headquarters F-term (reference) 4C066 AA09 BB01 CC01 JJ06 LL08                       QQ16

Claims (4)

[Claims] 1. A flow path comprising two or more inflow ports and one outflow port communicating with the two or more inflow ports via respective flow channels, wherein the flow channels from the two or more inflow ports are provided. It is a multi-branched flow channel pipe that merges at a merging portion, and the merged flow channel reaches an outflow port, and a part of the two or more inflow ports is pierced with a plug of a prefilled syringe. A road needle is attached, and the merging portion and the outlet are always in communication with each other,
A multi-branch flow channel pipe, which is provided with a flow channel switching mechanism that opens any one of the flow channels between the two or more inflow ports and the merging portion and closes the other. 2. The multi-branch flow tube according to claim 1, wherein the flow path needle is removable from an inflow port to which the flow path needle is attached. 3. The multi-branch flow tube according to claim 1, further comprising a flow path needle protection portion surrounding the flow path needle. 4. The method according to claim 1, further comprising two inflow ports, one of which has a flow path needle attached thereto and the other of which has no flow path needle attached thereto. The multi-branch flow pipe according to any one of claims.