JP2003206241A5 - - Google Patents
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- Publication number
- JP2003206241A5 JP2003206241A5 JP2002004250A JP2002004250A JP2003206241A5 JP 2003206241 A5 JP2003206241 A5 JP 2003206241A5 JP 2002004250 A JP2002004250 A JP 2002004250A JP 2002004250 A JP2002004250 A JP 2002004250A JP 2003206241 A5 JP2003206241 A5 JP 2003206241A5
- Authority
- JP
- Japan
- Prior art keywords
- ophthalmic
- pharmacologically active
- low molecular
- active compound
- ophthalmic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003732 agents acting on the eye Substances 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 3
- HIANJWSAHKJQTH-UHFFFAOYSA-N Pemirolast Chemical compound CC1=CC=CN(C2=O)C1=NC=C2C=1N=NNN=1 HIANJWSAHKJQTH-UHFFFAOYSA-N 0.000 claims 2
- RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 claims 2
- 229960004439 pemirolast Drugs 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- TWBNMYSKRDRHAT-RCWTXCDDSA-N (S)-timolol hemihydrate Chemical compound O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1 TWBNMYSKRDRHAT-RCWTXCDDSA-N 0.000 claims 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 1
- 229960005261 Aspartic Acid Drugs 0.000 claims 1
- RHLJLALHBZGAFM-UHFFFAOYSA-N Bunazosinum Chemical compound C1CN(C(=O)CCC)CCCN1C1=NC(N)=C(C=C(OC)C(OC)=C2)C2=N1 RHLJLALHBZGAFM-UHFFFAOYSA-N 0.000 claims 1
- 229940093632 Flavin-Adenine Dinucleotide Drugs 0.000 claims 1
- 208000010412 Glaucoma Diseases 0.000 claims 1
- RWSXRVCMGQZWBV-WDSKDSINSA-N Glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims 1
- 229960003180 Glutathione Drugs 0.000 claims 1
- 108010024636 Glutathione Proteins 0.000 claims 1
- LPLVUJXQOOQHMX-MYOOOWEVSA-N Glycyrrhizic acid Natural products O=C(O)[C@H]1[C@@H](O)[C@H](O)[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@H](C(=O)O)O2)[C@@H](O[C@@H]2C(C)(C)[C@H]3[C@@](C)([C@H]4C(=O)C=C5[C@](C)([C@]4(C)CC3)CC[C@]3(C)[C@H]5C[C@](C(=O)O)(C)CC3)CC2)O1 LPLVUJXQOOQHMX-MYOOOWEVSA-N 0.000 claims 1
- ZCVMWBYGMWKGHF-UHFFFAOYSA-N Ketotifene Chemical compound C1CN(C)CCC1=C1C2=CC=CC=C2CC(=O)C2=C1C=CS2 ZCVMWBYGMWKGHF-UHFFFAOYSA-N 0.000 claims 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 1
- 206010030043 Ocular hypertension Diseases 0.000 claims 1
- TVQZAMVBTVNYLA-UHFFFAOYSA-N Pranoprofen Chemical compound C1=CC=C2CC3=CC(C(C(O)=O)C)=CC=C3OC2=N1 TVQZAMVBTVNYLA-UHFFFAOYSA-N 0.000 claims 1
- 230000000172 allergic Effects 0.000 claims 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 1
- 235000003704 aspartic acid Nutrition 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 229960002467 bunazosin Drugs 0.000 claims 1
- 239000003093 cationic surfactant Substances 0.000 claims 1
- 229960002104 cyanocobalamin Drugs 0.000 claims 1
- 235000000639 cyanocobalamin Nutrition 0.000 claims 1
- 239000011666 cyanocobalamin Substances 0.000 claims 1
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 claims 1
- 229960001259 diclofenac Drugs 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- VWWQXMAJTJZDQX-UYBVJOGSSA-N flavin adenine dinucleotide Chemical compound C1=NC2=C(N)N=CN=C2N1[C@@H]([C@H](O)[C@@H]1O)O[C@@H]1CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C2=NC(=O)NC(=O)C2=NC2=C1C=C(C)C(C)=C2 VWWQXMAJTJZDQX-UYBVJOGSSA-N 0.000 claims 1
- 235000019162 flavin adenine dinucleotide Nutrition 0.000 claims 1
- 239000011714 flavin adenine dinucleotide Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 235000003969 glutathione Nutrition 0.000 claims 1
- 229960004949 glycyrrhizic acid Drugs 0.000 claims 1
- 239000001685 glycyrrhizic acid Substances 0.000 claims 1
- 235000019410 glycyrrhizin Nutrition 0.000 claims 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims 1
- 229960004958 ketotifen Drugs 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229960003101 pranoprofen Drugs 0.000 claims 1
- 229960004605 timolol Drugs 0.000 claims 1
- 229960000281 trometamol Drugs 0.000 claims 1
Claims (7)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002004250A JP2003206241A (en) | 2002-01-11 | 2002-01-11 | Ophthalmic agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002004250A JP2003206241A (en) | 2002-01-11 | 2002-01-11 | Ophthalmic agent |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003392022A Division JP2004043516A (en) | 2003-11-21 | 2003-11-21 | Ophthalmic agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003206241A JP2003206241A (en) | 2003-07-22 |
| JP2003206241A5 true JP2003206241A5 (en) | 2004-11-18 |
Family
ID=27643621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002004250A Pending JP2003206241A (en) | 2002-01-11 | 2002-01-11 | Ophthalmic agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2003206241A (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005072727A1 (en) * | 2004-01-29 | 2005-08-11 | Teika Pharmaceutical Co., Ltd. | Eye drop composition |
| JP2005263792A (en) * | 2004-02-19 | 2005-09-29 | Santen Pharmaceut Co Ltd | Clear latanoprost eye lotion |
| WO2005079809A1 (en) * | 2004-02-19 | 2005-09-01 | Santen Pharmaceutical Co., Ltd. | Transparent latanoprost eye drops |
| JP5434981B2 (en) * | 2004-02-27 | 2014-03-05 | 大正製薬株式会社 | Eye drops |
| JP4961671B2 (en) * | 2004-02-27 | 2012-06-27 | 大正製薬株式会社 | Eye drops |
| JP5575100B2 (en) * | 2004-12-28 | 2014-08-20 | ロート製薬株式会社 | Planoprofen-containing composition |
| JP4958401B2 (en) * | 2004-12-28 | 2012-06-20 | ロート製薬株式会社 | Planoprofen-containing composition |
| DE102005055275A1 (en) | 2005-11-17 | 2007-05-24 | Ursapharm Arzneimittel Gmbh & Co. Kg | Phosphate-free pharmaceutical composition and its use |
| EP2123278B1 (en) * | 2007-02-07 | 2013-01-09 | Teika Pharmaceutical Co., Ltd. | Eye drop preparation comprising latanoprost |
| JP5420877B2 (en) * | 2008-10-07 | 2014-02-19 | テイカ製薬株式会社 | Ophthalmic agent |
| JP2010132587A (en) * | 2008-12-03 | 2010-06-17 | Teika Seiyaku Kk | Ophthalmic agent |
| JP5489581B2 (en) * | 2009-06-29 | 2014-05-14 | ロート製薬株式会社 | Planoprofen-containing aqueous composition |
| TW201109325A (en) * | 2009-07-30 | 2011-03-16 | Wakamoto Pharma Co Ltd | Aqueous composition for eye drops |
| JP2011219412A (en) * | 2010-04-09 | 2011-11-04 | Saisentan Igaku Kenkyusho:Kk | Visual field-improving therapeutic agent for glaucoma |
| JP6704720B2 (en) * | 2014-12-12 | 2020-06-03 | 興和株式会社 | Aqueous composition |
| JP6918564B2 (en) * | 2017-05-01 | 2021-08-11 | 参天製薬株式会社 | Aqueous pharmaceutical composition |
-
2002
- 2002-01-11 JP JP2002004250A patent/JP2003206241A/en active Pending
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