JP2003149093A5 - - Google Patents

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JP2003149093A5
JP2003149093A5 JP2001350344A JP2001350344A JP2003149093A5 JP 2003149093 A5 JP2003149093 A5 JP 2003149093A5 JP 2001350344 A JP2001350344 A JP 2001350344A JP 2001350344 A JP2001350344 A JP 2001350344A JP 2003149093 A5 JP2003149093 A5 JP 2003149093A5
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Japan
Prior art keywords
liquid
dispensing apparatus
holding member
opening
layer
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Pending
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JP2001350344A
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Japanese (ja)
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JP2003149093A (en
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Priority to JP2001350344A priority Critical patent/JP2003149093A/en
Priority claimed from JP2001350344A external-priority patent/JP2003149093A/en
Publication of JP2003149093A publication Critical patent/JP2003149093A/en
Publication of JP2003149093A5 publication Critical patent/JP2003149093A5/ja
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Claims (20)

内部に保持された液体を先端の開口から吐出する液体分注装置であって、
第１の液体の層、前記第１の液体とは他の種類の液体であって前記第１の液体の層と接する第２の液体の層、の順で、前記開口の側から積層された液柱を、前記吐出前に予め内部に保持する液体保持部材と、
前記液柱に対して力を作用させることにより前記第１の液体を前記開口から吐出させる駆動手段と、
を備えることを特徴とする液体分注装置。 A liquid dispensing device that discharges liquid held inside from an opening at the tip ,
The first liquid layer, the first liquid is another kind of liquid, and the second liquid layer in contact with the first liquid layer is stacked in this order from the opening side. A liquid holding member for holding a liquid column in advance before the discharge;
Driving means for discharging the first liquid from the opening by applying a force to the liquid column;
Liquid dispensing device, characterized in that it comprises a. 前記第１の液体は、分析や検査に用いられる試料であることを特徴とする請求項１記載の液体分注装置。The liquid dispensing apparatus according to claim 1, wherein the first liquid is a sample used for analysis or inspection . 前記分析や検査に用いられる試料は、血液分析、遺伝子検査、創薬検査に用いられる試料であることを特徴とする請求項１または２記載の液体分注装置。The liquid dispensing apparatus according to claim 1 or 2, wherein the sample used for the analysis or test is a sample used for blood analysis, genetic test, or drug discovery test . 前記第２の液体は、超純水またはフロンであることを特徴とする請求項１記載の液体分注装置。The liquid dispensing apparatus according to claim 1, wherein the second liquid is ultrapure water or Freon. 前記駆動手段は、前記液柱に慣性力を作用させることにより前記第１の液体を前記開口から吐出させることを特徴とする請求項１記載の液体分注装置。2. The liquid dispensing apparatus according to claim 1, wherein the driving unit discharges the first liquid from the opening by applying an inertial force to the liquid column. 3. 前記液体保持部材に保持される前記第１の液体の量および前記第２の液体の量の合計量は、前記吐出時に作用する前記慣性力が得られる量であることを特徴とする請求項５記載の液体分注装置。6. The total amount of the first liquid and the second liquid held by the liquid holding member is an amount that provides the inertial force that acts during the ejection. The liquid dispensing apparatus as described. 前記駆動手段は、前記第１の液体の少なくとも一部を吐出させることを特徴とする請求項１記載の液体分注装置。The liquid dispensing apparatus according to claim 1, wherein the driving unit discharges at least a part of the first liquid. 前記駆動手段は、前記第２の液体を吐出させずに前記第１の液体を吐出させることを特徴とする請求項１記載の液体分注装置。The liquid dispensing apparatus according to claim 1, wherein the driving unit discharges the first liquid without discharging the second liquid. 前記液体保持部材に保持される前記第１の液体の量は、前記吐出時に吐出させる量よりも多い量であることを特徴とする請求項１記載の液体分注装置。The liquid dispensing apparatus according to claim 1, wherein an amount of the first liquid held by the liquid holding member is larger than an amount discharged during the discharge. 前記液体保持部材に保持される前記第１の液体の量は、前記吐出時に吐出させる量に予め解析して得られた量を加えた量であることを特徴とする請求項９記載の液体分注装置。10. The liquid component according to claim 9, wherein the amount of the first liquid held by the liquid holding member is an amount obtained by adding an amount obtained by analyzing in advance to an amount discharged at the time of discharging. Note device. 前記予め解析して得られた量は、前記第１の液体と前記第２の液体との相互拡散の影響を所定の吐出所要時間内に受ける可能性のある領域を、体積に換算した量であることを特徴とする請求項１０記載の液体分注装置。The amount obtained by the analysis in advance is an amount converted into a volume of a region that may be affected by the mutual diffusion between the first liquid and the second liquid within a predetermined required discharge time. The liquid dispensing apparatus according to claim 10, wherein the liquid dispensing apparatus is provided. 前記液体保持部材に保持される前記第１の液体および前記第２の液体は、前記吐出前に予め前記開口から前記液体保持部材の内部にそれぞれ吸引されることを特徴とする請求項１記載の液体分注装置。The said 1st liquid and said 2nd liquid hold | maintained at the said liquid holding member are each attracted | sucked from the said opening beforehand to the inside of the said liquid holding member before the said discharge, respectively. Liquid dispensing device. 前記開口から前記液体保持部材の内部に前記第２の液体が吸引された後に、前記第１の液体が吸引されることを特徴とする請求項１２記載の液体分注装置。The liquid dispensing apparatus according to claim 12, wherein the first liquid is sucked after the second liquid is sucked into the liquid holding member from the opening. 前記液体保持部材は、前記吐出前に予め、前記開口の側から前記第２の液体の層の次にThe liquid holding member is preliminarily placed next to the second liquid layer from the opening side before the ejection. 、前記第２の液体と接する圧縮性流体の層をさらに、内部に保持することを特徴とする請求項１記載の液体分注装置。The liquid dispensing apparatus according to claim 1, further comprising a layer of compressive fluid in contact with the second liquid held therein. 前記圧縮性流体は、空気であることを特徴とする請求項１４記載の液体分注装置。The liquid dispensing apparatus according to claim 14, wherein the compressive fluid is air. 前記液体保持部材に保持される前記第１の液体、前記第２の液体および前記圧縮性流体は、前記吐出前に予め前記開口から前記液体保持部材の内部にそれぞれ吸引されることを特徴とする請求項１４記載の液体分注装置。The first liquid, the second liquid, and the compressive fluid held by the liquid holding member are respectively sucked into the liquid holding member from the opening in advance before the discharge. The liquid dispensing apparatus according to claim 14. 前記液体保持部材は、前記第１の液体および前記第２の液体とは他の種類の液体であって前記圧縮性流体と接する第３の液体の層をさらに、前記開口の側から前記圧縮性流体の層の次に、前記吐出前に予め内部に保持することを特徴とする請求項１４記載の液体分注装置。The liquid holding member further includes a third liquid layer that is in contact with the compressive fluid, which is a different type of liquid from the first liquid and the second liquid, from the opening side. The liquid dispensing apparatus according to claim 14, wherein the liquid dispensing apparatus is previously held inside the fluid layer before the ejection. 前記第３の液体は、前記液体保持部材の内部を洗浄するための液体であることを特徴とする請求項１７記載の液体分注装置。The liquid dispensing apparatus according to claim 17, wherein the third liquid is a liquid for cleaning the inside of the liquid holding member. 前記第３の液体は、前記第１の液体の吐出後に前記液体保持部材の内部に送液され、前記液体保持部材の内部に残存している前記第１の液体および前記第２の液体を排出することを特徴とする請求項１８記載の液体分注装置。The third liquid is fed into the liquid holding member after discharging the first liquid, and discharges the first liquid and the second liquid remaining in the liquid holding member. The liquid dispensing apparatus according to claim 18, wherein the liquid dispensing apparatus is a liquid dispensing apparatus. 液体保持部材の内部に保持された液体を前記液体保持部材の先端の開口から吐出する液体分注方法であって、A liquid dispensing method for discharging a liquid held inside a liquid holding member from an opening at a tip of the liquid holding member,
前記液体保持部材の内部に、第１の液体の層、前記第１の液体とは他の種類の液体であって前記第１の液体の層と接する第２の液体の層、の順で、前記開口の側から積層された液柱を保持する工程と、Inside the liquid holding member, in the order of a first liquid layer, the first liquid is another type of liquid and is in contact with the first liquid layer, Holding the liquid column stacked from the opening side;
前記液柱に対して力を作用させることにより前記第１の液体を前記開口から吐出させる工程と、Discharging the first liquid from the opening by applying a force to the liquid column;
を行うことを特徴とする液体分注方法。A liquid dispensing method characterized in that:
JP2001350344A 2001-11-15 2001-11-15 Liquid dispensing apparatus and method therefor Pending JP2003149093A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2001350344A JP2003149093A (en) 2001-11-15 2001-11-15 Liquid dispensing apparatus and method therefor

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Application Number Priority Date Filing Date Title
JP2001350344A JP2003149093A (en) 2001-11-15 2001-11-15 Liquid dispensing apparatus and method therefor

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JP2003149093A JP2003149093A (en) 2003-05-21
JP2003149093A5 true JP2003149093A5 (en) 2005-07-14

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Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005069830A (en) * 2003-08-22 2005-03-17 Sysmex Corp Dispensation chip and analyzer using it
TWI422801B (en) * 2005-05-19 2014-01-11 Universal Bio Research Co Ltd Method of detecting dispensed quantity and liquid draw monitoring type dispensing device
JP4129692B2 (en) 2005-08-30 2008-08-06 セイコーエプソン株式会社 Biochip manufacturing method and biochip manufacturing apparatus
JP4778803B2 (en) * 2006-01-31 2011-09-21 富士通株式会社 Solution filling device
EP2012129A4 (en) * 2006-04-24 2013-12-04 Wako Pure Chem Ind Ltd Dispensing mechanism, dispensing apparatus and dispensing method for liquid to be dispensed
JP4910727B2 (en) * 2007-01-31 2012-04-04 セイコーエプソン株式会社 Inspection device
JP4910728B2 (en) * 2007-01-31 2012-04-04 セイコーエプソン株式会社 Inspection device and method of using the same
EP2163901A1 (en) * 2008-09-10 2010-03-17 Roche Diagnostics GmbH Method and metering device for metering a fluid into a receptacle channel of a testing element for bodily fluid analysis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2526582B2 (en) * 1987-05-25 1996-08-21 株式会社島津製作所 Sample dilution method
JP2515920Y2 (en) * 1989-04-27 1996-11-06 株式会社ニッテク Dispensing device
JP2783596B2 (en) * 1989-06-05 1998-08-06 株式会社東芝 Automatic chemical analyzer
JPH04329365A (en) * 1991-05-02 1992-11-18 Olympus Optical Co Ltd Sample separate injecting method
JPH1096735A (en) * 1996-09-25 1998-04-14 Aloka Co Ltd Aerial discharge type dispensing device
JP3694370B2 (en) * 1996-10-14 2005-09-14 アロカ株式会社 Dispensing device
JP2001235400A (en) * 2000-02-22 2001-08-31 Olympus Optical Co Ltd Liquid dispensing device and liquid dispensing method

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