JP2003081854A - Composition for improving constipation - Google Patents

Composition for improving constipation

Info

Publication number
JP2003081854A
JP2003081854A JP2002199224A JP2002199224A JP2003081854A JP 2003081854 A JP2003081854 A JP 2003081854A JP 2002199224 A JP2002199224 A JP 2002199224A JP 2002199224 A JP2002199224 A JP 2002199224A JP 2003081854 A JP2003081854 A JP 2003081854A
Authority
JP
Japan
Prior art keywords
composition
soybean
aqueous extract
improving
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002199224A
Other languages
Japanese (ja)
Other versions
JP4207477B2 (en
Inventor
Hiroyo Tsujino
浩代 辻野
Hideo Araki
秀雄 荒木
Yukio Hashimoto
征雄 橋本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fuji Oil Co Ltd
Original Assignee
Fuji Oil Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fuji Oil Co Ltd filed Critical Fuji Oil Co Ltd
Priority to JP2002199224A priority Critical patent/JP4207477B2/en
Publication of JP2003081854A publication Critical patent/JP2003081854A/en
Application granted granted Critical
Publication of JP4207477B2 publication Critical patent/JP4207477B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

PROBLEM TO BE SOLVED: To provide a composition for improving constipation with which effect for improving constipation is exhibited even when a small amount of the composition is used without depending on dietary therapy and administration of a medicine and which is utilizable for various foods and beverages and is excellent also in general purpose properties. SOLUTION: This composition comprises an aqueous extract obtained by subjecting a soybean hypocotyls to extraction with an aqueous solvent. When the composition is administered to a person having constipation, constipation is safely improved by a small amount of the intake of the composition.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【発明の属する技術分野】本発明は便通改善用途の組成
物に関する。
TECHNICAL FIELD The present invention relates to a composition for improving bowel movements.

【0002】[0002]

【従来の技術】食生活の変化や日常生活の習慣等から、
生活習慣病と呼ばれる疾病が大きな問題となってきてい
る。主要な疾病の一つとして、肉や卵等の脂質含有の高
い高エネルギー食品の摂取過多、食物繊維摂取量の減少
等に起因する便秘等が挙げられ、慢性的な便秘にかかっ
ている人も少なくない。中には2〜3日の便秘だけでな
く、1週間〜10日も排便できない人もいる。便秘にな
ると腸が老廃物を吸収してしまうため、体調不良の原因
ともなる。便秘が習慣化すると、異常発酵したガスが腸
内にたまりお腹の張りや痛みを引き起こしたり、肌荒れ
等の影響もある。また、腸粘膜にも悪影響を与え、直腸
癌等の疾病に発展させる危険もあり、早期に治療するこ
とが重要である。
2. Description of the Related Art Due to changes in eating habits and habits of daily life,
A disease called lifestyle-related disease has become a big problem. One of the major diseases is excessive intake of high-energy foods with high lipid content such as meat and eggs, constipation caused by decreased dietary fiber intake, etc., and some people suffer from chronic constipation. Not a few. Some people may not have bowel movements for a week to 10 days as well as constipation for a few days. If you have constipation, your intestines will absorb waste products, which may cause you to feel unwell. When constipation becomes a habit, abnormally fermented gas accumulates in the intestines, causing bloating and pain in the abdomen, and rough skin. In addition, there is a risk that the intestinal mucosa may be adversely affected and a disease such as rectal cancer may develop, so that early treatment is important.

【0003】これらの観点から、難消化性デキストリ
ン、ポリデキストロース、セルロース等の食物繊維を含
む健康食品が多く見られる(特許第2779616号等)。ま
た、緩下剤の働きをするセンナ等の成分を含む健康食品
も出回っている。しかしながら、食餌療法は過度な制限
食になることが多く、欧風の食事に慣れた現代社会にお
いて、長期に渡る食餌制限を実行するには非常に困難を
伴う。また食物繊維は、便通改善の効果を発揮するのに
まとまった量の摂取が必要であり、例えばこれを少量添
加した飲料を摂取しても目立った効果のない場合があっ
た。さらに食品へ添加した場合には食感にざらつきが出
る場合があること等から、継続的摂取に困難があった。
一方、市販されている緩下剤は緩下作用が強すぎるた
め、使用法が難しいという難点があった。
From these viewpoints, many health foods containing dietary fibers such as indigestible dextrin, polydextrose and cellulose are found (Japanese Patent No. 2779616). In addition, health foods containing ingredients such as senna that act as a laxative are on the market. However, diet is often an excessively restricted diet, and it is very difficult to carry out long-term dietary restriction in the modern society accustomed to a European diet. Further, dietary fiber needs to be ingested in a large amount in order to exert the effect of improving bowel movements, and, for example, ingesting a beverage containing a small amount of this may not have a noticeable effect. Furthermore, when added to foods, the texture may be rough, so continuous intake is difficult.
On the other hand, since the laxatives on the market have too strong laxative action, they are difficult to use.

【0004】他方、大豆には、イソフラボンやサポニン
等の微量成分が含まれており、種々の生理機能を持つと
されている。最近では、イソフラボンは骨粗鬆症や癌の
予防、更年期障害の症状緩和などの研究がなされてい
る。また、大豆中にはサポニンも含まれている。サポニ
ンについても生理作用の報告が種々なされており、抗酸
化作用をはじめ、抗肥満効果、肝機能改善効果などが報
告されている。しかしながら、これらの微量成分が便通
改善に及ぼす影響についてはまだ検討されていない。以
上より、少量の摂取で顕著な便通改善効果を発揮し、手
軽に継続摂取が可能であり、食品に添加しやすい便通改
善用組成物が求められている。
On the other hand, soybean contains trace components such as isoflavone and saponin and is said to have various physiological functions. Recently, isoflavones have been studied for prevention of osteoporosis and cancer, and symptom relief of menopausal disorders. Soybean also contains saponin. Various reports have been made on the physiological action of saponin, and the anti-obesity effect, the liver function improving effect, and the like as well as the antioxidant effect have been reported. However, the effects of these trace components on improving bowel movements have not yet been investigated. From the above, there is a demand for a composition for improving bowel movements, which exhibits a marked bowel movement improving effect even when ingested in a small amount, can be easily continuously ingested, and is easily added to foods.

【0005】[0005]

【発明が解決しようとする課題】本発明は、上記課題を
解決し、食事療法や薬物投与によらず少量で便通の改善
に優れた効果を発揮し、幅広い飲食物に利用可能な汎用
性にも優れた便通改善用組成物を提供することを目的と
するものである。
DISCLOSURE OF THE INVENTION The present invention solves the above-mentioned problems and exerts an excellent effect of improving bowel movements in a small amount regardless of diet therapy and drug administration, and has general versatility applicable to a wide range of foods and drinks. Another object is to provide an excellent composition for improving bowel movements.

【0006】[0006]

【課題を解決するための手段】本発明者らは、上記課題
に対し鋭意研究を重ねた結果、意外にも、大豆や大豆胚
軸を水性溶媒で抽出した水性抽出物(イソフラボン、サ
ポニン、オリゴ糖含有)を便秘の人に投与することによ
り、少量の摂取かつ安全に便通が改善されることを見出
し、本発明を完成させた。すなわち本発明は、 (1)大豆由来の水性抽出物を含有することを特徴とす
る便通改善用組成物、 (2)該水性抽出物に乾燥重量中イソフラボンが0.3
〜20重量%、サポニンが0.5〜30重量%が含まれ
る上記(1)に記載の便通改善用組成物。 (3)該水性抽出物に乾燥重量中オリゴ糖が5〜40重
量%含まれる上記(2)に記載の便通改善用組成物。 (4)該水性抽出物が大豆胚軸由来又は大豆ホエー由来
である上記(1)〜(3)の何れかに記載の便通改善用
組成物。 (5)イソフラボン及びサポニンが重量換算で0.3〜
20:0.5〜30比率で含有する便通改善用組成物。 (6)イソフラボン、サポニン及びオリゴ糖が重量換算
で0.3〜20:0.5〜30比率で含有する便通改善
用組成物。 (7)オリゴ糖が大豆オリゴ糖である上記(3)、
(4)又は(6)の何れかに記載の便通改善用組成物。 (8)整腸作用を示す原料をさらに含有する上記(1)
〜(7)の何れかに記載の便通改善組成物。
Means for Solving the Problems As a result of intensive studies on the above problems, the present inventors have surprisingly found that an aqueous extract (isoflavone, saponin, oligo, etc.) obtained by extracting soybean or soybean hypocotyl with an aqueous solvent. It was found that the administration of (containing sugar) to a person with constipation improves the bowel movement safely with a small amount of ingestion and completed the present invention. That is, the present invention provides (1) a composition for improving bowel movements, which comprises an aqueous extract derived from soybeans, (2) an isoflavone in a dry weight of 0.3 in the aqueous extract.
The composition for improving bowel movements according to (1) above, wherein the composition comprises -20% by weight and saponin 0.5-30% by weight. (3) The composition for improving bowel movements according to (2), wherein the aqueous extract contains 5 to 40% by weight of oligosaccharide in a dry weight. (4) The composition for improving bowel movements according to any one of (1) to (3) above, wherein the aqueous extract is derived from soybean hypocotyl or soybean whey. (5) Isoflavone and saponin are 0.3-by weight conversion.
A composition for improving bowel movements, which is contained in a ratio of 20: 0.5 to 30. (6) A composition for improving bowel movement containing isoflavone, saponin and oligosaccharide in a weight ratio of 0.3 to 20: 0.5 to 30. (7) The above (3), wherein the oligosaccharide is soybean oligosaccharide,
The composition for improving bowel movements according to either (4) or (6). (8) The above (1), which further contains a raw material having an intestinal regulating action.
The bowel movement-improving composition according to any one of to (7).

【0007】[0007]

【発明の実施の形態】以下、本発明を詳しく説明する。
本発明の便通改善用組成物は大豆由来の水性抽出物を含
有することに特徴がある。まず大豆由来の水性抽出物に
ついて説明する。本発明において、大豆由来の水性抽出
物の抽出原料として、丸大豆、脱皮大豆、脱皮脱胚軸大
豆、脱脂大豆、大豆胚軸等を原料とすることができる。
特に原料としてはイソフラボンやサポニンの微量成分の
含量が比較的高い大豆胚軸を用いることが好適である。
大豆の産地や抽出前の加工の有無には限定されず、乾燥
処理、加熱処理等を施すことができる。特に抽出後の組
成物の風味を考慮すれば、青臭味や渋味のない加熱処理
原料を抽出に供することが汎用性に優れ、好適である。
加熱処理は生の状態の青臭味や渋味を抑える程度に行え
ばよく、乾熱加熱や湿熱加熱の何れの加熱方法でも構わ
ない。例えば特開平10−4904号公報に記載されているよ
うに、ガスロースターや熱風ロースター等の焙煎機を用
い、所望の色調が得られるまで原料の焙煎を行うことが
できる。
BEST MODE FOR CARRYING OUT THE INVENTION The present invention is described in detail below.
The composition for improving bowel movements of the present invention is characterized by containing an aqueous extract derived from soybean. First, the soybean-derived aqueous extract will be described. In the present invention, as the extraction raw material of the aqueous extract derived from soybean, whole soybean, dehulled soybean, dehulled hypocotyl soybean, defatted soybean, soybean hypocotyl and the like can be used.
In particular, it is preferable to use soybean hypocotyl having a relatively high content of trace components such as isoflavone and saponin as the raw material.
The place of production of soybean and the presence or absence of processing before extraction are not limited, and drying treatment, heat treatment, or the like can be performed. In particular, considering the flavor of the composition after extraction, it is preferable to use a heat-treated raw material having no blue odor or astringency for extraction because of its excellent versatility.
The heat treatment may be carried out to the extent that the green odor and astringency in the raw state are suppressed, and any heating method such as dry heat heating or wet heat heating may be used. For example, as described in JP-A-10-4904, a roasting machine such as a gas roaster or a hot-air roaster can be used to roast the raw materials until a desired color tone is obtained.

【0008】次に抽出原料から水性抽出物を調製する方
法について例示する。抽出原料は全粒のままでも粉砕、
圧扁、膨化破砕等の物理的処理をしたものの何れも抽出
に供することが可能である。特に脂質を含有する原料を
用いる場合、物理的処理により原料の表層部を壊さずに
抽出に供すると、抽出原料内部に10重量%程度も含有
している脂質や油溶性成分の漏出を防ぐことができ、溶
解性、風味の保存性の点で汎用性に優れた水性抽出物を
得ることが出来るため好適である。
Next, a method for preparing an aqueous extract from an extraction raw material will be exemplified. Extraction raw material is crushed even if it is whole grain,
Any of those subjected to physical treatment such as pressing and expansion and crushing can be used for extraction. Especially when using a lipid-containing raw material, if it is subjected to extraction without destroying the surface layer of the raw material by physical treatment, it is possible to prevent leakage of lipids and oil-soluble components containing about 10% by weight inside the extracted raw material. This is preferable because it is possible to obtain an aqueous extract excellent in versatility in terms of solubility and storability of flavor.

【0009】水性抽出物の抽出に用いる溶媒としては、
水あるいは含水アルコール(例えばメタノール、エタノ
ール、プロパノール)等の水性溶媒を使用することが適
当であり、特に水が好適である。抽出の方法としては浸
漬抽出、撹拌抽出或いは向流抽出等の種々の方法で行え
ばよい。一方、ヘキサン、アセトン等の疎水性の高い有
機溶媒で抽出すると、抽出原料内部に含有している脂質
や油溶性成分を漏出させたり、疎水性の悪風味成分が同
時に抽出されるため好ましくない。水性溶媒による抽出
温度は特に限定されないが、有効成分を効率良く抽出で
きる点で、4〜150℃、好ましくは80〜100℃が
適当である。また、抽出後の抽出液と抽出残渣の固液分
離は、抽出残渣の内部に含有している脂質や油溶性成分
等の滲出を防ぐために、抽出残渣を圧搾せず行うのこと
が望ましい。抽出液は原液のまま、或いは濃縮液とし
て、或いは乾燥粉末として加工し、「水性抽出物」とす
ることができる。
As the solvent used for extraction of the aqueous extract,
It is appropriate to use an aqueous solvent such as water or a hydrous alcohol (eg methanol, ethanol, propanol), and water is particularly preferable. As the extraction method, various methods such as immersion extraction, stirring extraction or countercurrent extraction may be used. On the other hand, extraction with a highly hydrophobic organic solvent such as hexane and acetone is not preferable because the lipid and oil-soluble components contained in the extraction raw material are leaked out and the hydrophobic malodorous component is simultaneously extracted. The extraction temperature with the aqueous solvent is not particularly limited, but from the viewpoint that the active ingredient can be efficiently extracted, 4 to 150 ° C, preferably 80 to 100 ° C is suitable. In addition, it is desirable that the solid-liquid separation of the extraction liquid and the extraction residue after extraction is performed without squeezing the extraction residue in order to prevent the lipid, oil-soluble components, etc. contained in the extraction residue from seeping out. The extract can be processed as a neat solution, as a concentrated solution, or as a dry powder to obtain an "aqueous extract".

【0010】また、大豆ホエーを水性抽出物として利用
することが可能である。大豆ホエーとは広義に解釈し、
分離大豆たん白ホエー、濃縮大豆たん白の酸もしくはア
ルコール浸漬液や、豆乳・豆腐製造時の「呉」等も含ま
れる。分離大豆たん白ホエーは、分離大豆たん白製造時
に副産物として生ずるものであり、例えば脱脂大豆粉か
ら豆乳を調製し、これに塩酸等の酸を加えて大豆たん白
を等電点沈殿させて、上清を回収して得ることができ
る。濃縮大豆たん白の浸漬液は、例えば脱脂大豆粉に酸
又はアルコールを加えて、加熱・撹拌等を行い、大豆た
ん白以外の成分を溶出させて得られる。また呉は豆乳・
豆腐製造時の副産物であり、例えば丸大豆に熱水を加え
て加熱・撹拌等を行い、大豆たん白以外の成分を溶出さ
せて得られる。
It is also possible to use soy whey as an aqueous extract. Interpreted broadly as soy whey,
Separated soy protein whey, concentrated soy protein acid or alcohol immersion liquid, "Kure" at the time of soy milk / tofu production, etc. are also included. Separated soybean protein whey is generated as a by-product during the production of separated soybean protein, for example, soybean milk is prepared from defatted soybean powder, and an acid such as hydrochloric acid is added to the soybean protein to isoelectrically precipitate the soybean protein, It can be obtained by collecting the supernatant. The dipping solution of concentrated soybean protein can be obtained, for example, by adding acid or alcohol to defatted soybean powder, heating and stirring, and eluting components other than soybean protein. Kure is soy milk
It is a by-product during the production of tofu, and is obtained by, for example, adding hot water to whole soybeans, heating and stirring the mixture, and eluting components other than soybean protein.

【0011】得られた水性抽出物は幅広い薬剤や飲食品
等の組成物に添加する。ただし、pH2〜5.5の酸性域
の飲料やデザートに対しては製造時あるいは保存中にた
ん白質等の不溶化による白濁や沈殿を生じる場合があ
り、便通改善効果はあっても外観上の商品価値が損なわ
れる可能性がある。このような場合には、水性抽出物を
更に酸性化での溶解性を高める手段で処理することが好
ましい。溶解性を高める手段としては、水性抽出物をサ
イクロデキストリンで包接してさらに溶解性を高める方
法などを用いることができる。
The obtained aqueous extract is added to a wide variety of compositions such as medicines and foods and drinks. However, for beverages and desserts in the acidic range of pH 2 to 5.5, white turbidity or precipitation may occur during production or storage due to insolubilization of proteins, etc., and there is an effect of improving bowel movements, but a cosmetic product Value may be lost. In such cases, it is preferred to treat the aqueous extract with a means that further enhances its solubility upon acidification. As a means for enhancing the solubility, a method of further encapsulating the aqueous extract with cyclodextrin to further enhance the solubility can be used.

【0012】酸性化での溶解性を高めるための、より好
ましい方法としては、pH2〜5.5にpH調整剤により調
整し、必要により冷却(好ましくは10℃以下)し、ろ
過、遠心分離等により酸性において不溶となる成分を除
去しい、酸性域においても濁りや沈殿を生じない「酸性
可溶抽出物」を得る方法が挙げられる。この場合、pH調
整剤としては、通常食品製造業において使用が許可され
ている無機酸、有機酸であれば何れのものでも使用でき
る。また、水性抽出物を酸性に調整する際、たん白質等
の不溶物と共にイソフラボン等の有効成分が沈殿(共
沈)して有効成分のロスが多い場合は、pH調整前に予
め水性抽出物にプロテアーゼを作用させ、たん白質を低
分子化することにより、有効成分のロスを防止すること
が可能である。このようにして得られた酸性可溶抽出物
は、原液のまま利用しても良いし、濃縮液、或いは乾燥
粉末として利用することも可能である。酸性可溶抽出物
はpH2〜5.5の酸性域において溶解性が向上してお
り、乳酸菌飲料や果実飲料等のpH5.5以下の酸性飲料
への利用に特に適する。
As a more preferable method for increasing the solubility in acidification, pH is adjusted to pH 2 to 5.5 with a pH adjuster, cooled if necessary (preferably 10 ° C. or lower), filtered, centrifuged, etc. Thus, a method of obtaining an "acid-soluble extract" in which components that are insoluble in acid are not removed and turbidity or precipitation does not occur even in an acidic region can be mentioned. In this case, as the pH adjuster, any inorganic acid or organic acid that is normally allowed to be used in the food manufacturing industry can be used. In addition, when the aqueous extract is adjusted to be acidic, if the active ingredients such as isoflavone precipitate (coprecipitate) along with insoluble substances such as proteins and there is a large loss of the active ingredients, the aqueous extract is prepared in advance before pH adjustment. It is possible to prevent the loss of the active ingredient by lowering the molecular weight of the protein by allowing a protease to act. The acidic soluble extract thus obtained may be used as it is as a stock solution, or as a concentrated solution or a dry powder. The acid-soluble extract has improved solubility in the acidic range of pH 2 to 5.5, and is particularly suitable for use in acidic drinks having a pH of 5.5 or less such as lactic acid bacteria drinks and fruit drinks.

【0013】本発明の大豆由来の水性抽出物の乾燥重量
当りの成分組成は原料や抽出条件によっても異なってく
るが、概ね脂質が2重量%以下、イソフラボン0.3〜
20重量%、サポニン0.5〜30重量%、オリゴ糖
(ラフィノース及びスタキオースの総量)が5〜40重
量%となる。上記のより好ましい抽出条件では、概ね脂
質が1重量%以下、イソフラボンが3〜20重量%、サ
ポニンが1.5〜20重量%、オリゴ糖が10〜25重
量%となる。
The composition of the soybean-derived aqueous extract of the present invention per dry weight varies depending on the raw material and the extraction conditions, but generally the lipid content is 2% by weight or less, and isoflavone 0.3-.
20% by weight, saponin 0.5 to 30% by weight, and oligosaccharides (total amount of raffinose and stachyose) become 5 to 40% by weight. Under the above more preferable extraction conditions, the lipid content is generally 1% by weight or less, the isoflavone content is 3 to 20% by weight, the saponin content is 1.5 to 20% by weight, and the oligosaccharide content is 10 to 25% by weight.

【0014】得られた水性抽出物は微量の摂取でも優れ
た便通改善効果を発揮するので、この水性抽出物を各種
組成物に添加し、本発明の便通改善用組成物とすること
ができる。組成物への添加量は、乾燥重量として0.0
5〜80重量%、好ましくは0.1〜50重量%であれ
ばよい。0.05重量%未満であると組成物として多量
に摂取する必要があり、実用的ではない。また80重量
%を超えると大豆由来の独特の風味が目立つようにな
り、人によっては摂取しにくくなる。
The obtained aqueous extract exerts an excellent bowel movement-improving effect even when ingested in a small amount, and therefore, the aqueous extract can be added to various compositions to prepare the composition for bowel movement improvement of the present invention. The amount added to the composition is 0.0 as a dry weight.
It may be 5 to 80% by weight, preferably 0.1 to 50% by weight. If it is less than 0.05% by weight, it is necessary to ingest a large amount as a composition, which is not practical. On the other hand, if it exceeds 80% by weight, the unique flavor derived from soybeans becomes noticeable, and it becomes difficult for some people to take.

【0015】本発明の便通改善用組成物の1日あたりの
摂取量は、組成物の形態によって適宜設定すれば良い
が、少量でかつ有意な改善効果を得るためには、イソフ
ラボンとして5〜100mg、サポニンとして3〜100
mgとするのが好適であり、オリゴ糖としては20〜50
0mgとするのがさらに好適である。これらの数値範囲未
満の摂取量であれば、有意な改善効果を得にくく、これ
らの数値範囲を超える摂取量であれば、組成物の摂取量
が多くなり、カロリー過多等の問題が生ずる可能性があ
る。
The daily intake of the composition for improving bowel movement of the present invention may be appropriately set depending on the form of the composition, but in order to obtain a small and significant improving effect, 5-100 mg of isoflavone is obtained. , 3 to 100 as saponin
It is preferable to set it as mg, and as the oligosaccharide, 20 to 50
More preferably, it is 0 mg. If the intake amount is less than these numerical ranges, it is difficult to obtain a significant improvement effect, and if the intake amount exceeds these numerical ranges, the intake amount of the composition increases, and problems such as excessive calories may occur. There is.

【0016】本発明の便通改善用組成物がこのように微
量の摂取でも優れた便通改善効果を発揮する機構は未だ
明確ではないが、大豆中に含まれるイソフラボン及びサ
ポニンなどの微量の生理活性物質が水性抽出物として濃
縮され、それらの共存による相乗効果により、微量の摂
取でも強い便秘改善効果を発揮するのではないかと推測
される。
Although the mechanism by which the composition for improving bowel movements of the present invention exerts an excellent effect of improving bowel movements even when ingested in such a small amount, the trace amount of physiologically active substances such as isoflavone and saponin contained in soybean is not clear. Is concentrated as an aqueous extract, and due to the synergistic effect of their coexistence, it is speculated that even a small amount of ingestion may exert a strong effect of improving constipation.

【0017】大豆由来の成分で便通改善効果を発揮しう
るものとしては、大豆オリゴ糖が知られており、その主
体はラフィノース、スタキオースである。丸大豆中には
ラフィノース約1%、スタキオース約4%程度含まれ、
大豆胚軸中にはラフィノース約2%、スタキオース約6
%程度含まれているため、本発明の水性抽出物に大豆オ
リゴ糖が含まれている場合には、イソフラボン及びサポ
ニンとの共存により、さらに相乗的に作用しうる。
As a soybean-derived component capable of exhibiting a bowel movement-improving effect, soybean oligosaccharide is known, and its main components are raffinose and stachyose. Whole soybean contains about 1% raffinose and about 4% stachyose,
About 2% raffinose and about 6 stachyose in soybean hypocotyl
%, So that when the aqueous extract of the present invention contains soybean oligosaccharide, coexistence with isoflavone and saponin can further act synergistically.

【0018】大豆オリゴ糖のみによる便通改善効果を望
むためには、1日にオリゴ糖として1〜3g程度の摂取
が必要とされており、これは大豆に換算すれば20〜6
0g程度、大豆胚軸では12〜40g程度にも相当し、
多量の摂取が必要となる。しかし、本発明における水性
抽出物は、大豆オリゴ糖として微量の摂取であっても優
れた効果を発揮するのである。
In order to obtain a bowel movement-improving effect of only soybean oligosaccharides, it is necessary to ingest 1 to 3 g of oligosaccharides per day, which is 20 to 6 when converted to soybeans.
About 0g, soybean hypocotyl corresponds to about 12-40g,
A large amount of intake is required. However, the aqueous extract of the present invention exerts an excellent effect as a soybean oligosaccharide even if it is ingested in a small amount.

【0019】上記水性抽出物は各種組成物への添加、す
なわち経口薬剤や飲食品への添加により、便通改善用組
成物とすることができる。経口薬剤の例としては、錠
剤、カプセル剤、顆粒剤、粉剤、ドリンク剤等、一般の
薬剤の形態が挙げられる。また食品の例としてはタブレ
ット、クッキー、ビスケット、クラッカー、シリアル、
スナック、チップ、キャンデー、ガム、チョコレート等
の洋菓子類や、パン、ケーキ等のベーカリー類や、饅
頭、団子、羊かん、煎餅、おかき、あられ等の和菓子類
や、アイスクリーム、アイスキャンデー等の冷菓や、ラ
ーメン、うどん、そば、素麺等の麺類や、米飯類や、牛
乳、ヨーグルト、チーズ、クリーム等の乳製品や、ジャ
ム、ピーナッツクリーム、バター、マーガリン等のスプ
レッド類や、茶葉系飲料、コーヒー、乳飲料、豆乳、果
実飲料、野菜飲料等の飲料や、プリン、ゼリー、ババロ
ア、ムース、杏仁豆腐等のデザートが挙げられる。水性
抽出物の添加方法は特に限定されず、各々の組成物の製
法に合わせて使用すれば良い。
The above aqueous extract can be made into a composition for improving bowel movements by adding it to various compositions, that is, adding it to oral medicines and foods and drinks. Examples of oral drugs include general drug forms such as tablets, capsules, granules, powders and drinks. Examples of food include tablets, cookies, biscuits, crackers, cereals,
Western sweets such as snacks, chips, candy, gum and chocolate, bakeries such as bread and cakes, Japanese sweets such as buns, dumplings, sheep cans, rice crackers, oysters and hail, frozen desserts such as ice cream and ice lollies. , Ramen, udon, soba, noodles such as noodles, cooked rice, dairy products such as milk, yogurt, cheese, cream, spreads such as jam, peanut cream, butter, margarine, tea leaf drinks, coffee, Drinks such as milk drinks, soy milk, fruit drinks, and vegetable drinks, and desserts such as pudding, jelly, bavarois, mousse, and almond tofu can be mentioned. The method of adding the aqueous extract is not particularly limited, and may be used according to the production method of each composition.

【0020】本発明の便通改善用組成物は上記に記載し
たように、大豆由来の水性抽出物を添加して得ることが
できるが、それに寄らず、イソフラボン及びサポニン、
さらにはオリゴ糖をそれぞれ組成物に添加・混合して便
通改善用組成物とすることも可能である。組成物中のイ
ソフラボン及びサポニンの含有比率は重量換算で0.3
〜20:0.5〜30が好ましく、3〜20:1.5〜
20がより好ましい。さらにオリゴ糖を添加する場合
は、上記比率に対し、5〜40が好ましく、10〜20
がより好ましい。この場合、各成分は市販の高純度製品
を使用することができる。
As described above, the composition for improving bowel movements of the present invention can be obtained by adding an aqueous extract derived from soybean, but isoflavone and saponin,
Furthermore, it is also possible to add and mix oligosaccharides to the composition to prepare a composition for improving bowel movements. The content ratio of isoflavone and saponin in the composition is 0.3 in terms of weight.
-20: 0.5-30 is preferable, and 3-20: 1.5-
20 is more preferable. When an oligosaccharide is further added, it is preferably 5 to 40, and 10 to 20 relative to the above ratio.
Is more preferable. In this case, a commercially available high-purity product can be used as each component.

【0021】さらに、上記の組成物には他の整腸作用を
示す原料を共に添加することにより、さらに優れた効果
を得ることができる。整腸作用を示す原料としては、一
般に整腸作用を効能として生ずる原料として公知のもの
を単独又は併用して使用することができ、例えば乳酸
菌、大豆オリゴ糖以外のオリゴ糖、食物繊維やグルコン
酸が挙げられる。乳酸菌の例としては、ラクトバシルス
属(ラクトバシルス・カゼイ、同・アシドフィラス、同
・ヘルベティカス、同・プランタラム、同・ケフィア、
同・マリ、同・ブルガリカス等)、ストレプトコッカス
属(ストレプトコッカス・サーモフィラス等)、ラクト
コッカス属(ラクトコッカス・ラクチス、ラクトコッカ
ス・クレモリス等)、ビフィドバクテリウム属(ビフィ
ドバクテリウム・ビフィダム、同・ロンガム、同・ブレ
ーベ、同・カテヌラータム等)等の一般にヨーグルトや
整腸剤として使用されているものが挙げられる。大豆オ
リゴ糖以外のオリゴ糖としては、フラクトオリゴ糖、マ
ルトオリゴ糖、ガラクトオリゴ糖、マンノオリゴ糖、イ
ソマルトオリゴ糖、キシロオリゴ糖、乳果オリゴ糖等が
挙げられる。食物繊維としては、セルロース、ヘミセル
ロース、難消化性デキストリン、ポリデキストロース、
ペクチン、ガム類、キチン、キトサン、小麦胚芽、ふす
ま等が挙げられる。
Furthermore, by adding other raw materials having an intestinal regulating action to the above composition, more excellent effects can be obtained. As the raw material exhibiting an intestinal regulating action, generally known ones which produce an intestinal regulating action as an effect can be used alone or in combination, and examples thereof include lactic acid bacteria, oligosaccharides other than soybean oligosaccharides, dietary fiber and gluconic acid. Is mentioned. Examples of lactic acid bacteria include the genus Lactobacillus (Lactobacillus casei, the same Acidophilus, the same Helveticus, the same plantarum, the same kefir,
The same, Mali, the same, Bulgaricus, etc.), Streptococcus (Streptococcus thermophilus, etc.), Lactococcus (Lactococcus lactis, Lactococcus cremoris, etc.), Bifidobacterium (Bifidobacterium bifidum, the same)・ Longum, the same breve, the same cateneratum, etc.) that are generally used as yogurt or an intestinal stabilizer. Examples of oligosaccharides other than soybean oligosaccharides include fructooligosaccharides, maltooligosaccharides, galactooligosaccharides, mannooligosaccharides, isomaltooligosaccharides, xylooligosaccharides, and milk fruit oligosaccharides. As dietary fiber, cellulose, hemicellulose, indigestible dextrin, polydextrose,
Pectin, gums, chitin, chitosan, wheat germ, bran and the like can be mentioned.

【0022】また添加する組成物の形態に合わせ、必要
に応じて糖質原料、油脂原料、蛋白質原料、ミネラル
類、ビタミン類、甘味料、調味料、酸味料、乳化剤、賦
形剤その他の食品衛生法上認められる食品原料・食品添
加物を組み合わせて配合することができる。
Further, depending on the form of the composition to be added, if necessary, sugar raw materials, fats and oils raw materials, protein raw materials, minerals, vitamins, sweeteners, seasonings, acidulants, emulsifiers, excipients and other foods. It is possible to mix and combine food raw materials and food additives that are recognized by the Sanitation Law.

【0023】本発明の便通改善用組成物は、医薬品のよ
うな化学合成物でなく、大豆由来の抽出物や成分を原料
とするため、副作用等の問題もなく、消費者が安心して
継続的に摂取することができる。また本発明は便通改善
効果を得るために安価で従来副産物として廃棄されてき
た大豆胚軸や大豆ホエーも有効に活用できるものであ
り、代表的現代病である便秘の改善を目的とした、副産
物の新規な利用方法としても非常に有効なものである。
Since the composition for improving bowel movements of the present invention is made of soybean-derived extracts and ingredients rather than chemical compounds such as pharmaceuticals, there are no problems such as side effects, and consumers can continue with peace of mind. Can be ingested. Further, the present invention can effectively utilize soybean hypocotyl and soybean whey that have been conventionally discarded as by-products at a low price in order to obtain a bowel movement-improving effect, and a by-product aimed at improving constipation which is a typical modern disease. It is also very effective as a new usage method of.

【0024】[0024]

【実施例】以下、本発明の実施例を示すが、本発明がこ
れらによってその技術範囲が限定されるものではない。
EXAMPLES Examples of the present invention will be shown below, but the technical scope of the present invention is not limited thereto.

【0025】<製造例1> (大豆胚軸からの水性抽
出物の調製) 大豆胚軸10kgをガスロースターを用いて140℃の熱風で2
0分間乾熱加熱処理した。乾熱加熱処理した大豆胚軸10k
gに熱水100kgを加え98℃で10分間加熱抽出した。その
後、抽出液を分離し、残渣に熱水を100kgを加え再度98
℃で10分間加熱抽出した。ついで両抽出液を混合し、減
圧濃縮後スプレー乾燥により抽出粉末4kgを得た。表1
に乾燥固形分中の成分組成を示した。なお、たん白質は
ケルダール法により、脂質はクロロホルム−メタノール
抽出法により、灰分は直接灰化法、イソフラボンは
(財)日本健康・栄養食品協会の大豆イソフラボン食品
規格基準分析法により、サポニン及びオリゴ糖はHPL
C法により測定した。オリゴ糖量はラフィノース及びス
タキオースの総量とした。以下の製造例2〜4も同様に
測定した。
<Production Example 1> (Preparation of Aqueous Extract from Soybean Hypocotyl) 10 kg of soybean hypocotyl was heated to 140 ° C. with a hot air using a gas roaster.
Dry heat treatment was performed for 0 minutes. Soybean hypocotyl 10k that was heat treated by dry heat
100 kg of hot water was added to g, and the mixture was heated and extracted at 98 ° C for 10 minutes. After that, the extract is separated, 100 kg of hot water is added to the residue, and 98
It was extracted by heating at 0 ° C for 10 minutes. Then, both extracts were mixed, concentrated under reduced pressure, and spray-dried to obtain 4 kg of an extracted powder. Table 1
The composition of the dry solids is shown in Table 1. The saponins and oligosaccharides were analyzed by the Kjeldahl method for proteins, the chloroform-methanol extraction method for lipids, the direct ash method for ash, and the soy isoflavone food standard analysis method of the Japan Health and Nutrition Food Association for isoflavones. Is HPL
It was measured by the C method. The amount of oligosaccharide was the total amount of raffinose and stachyose. The following Production Examples 2 to 4 were similarly measured.

【0026】<製造例2> (大豆胚軸からの酸性可
溶抽出物の調製) 大豆胚軸80kgをガスロースターを用いて140℃の熱風で2
0分間乾熱加熱処理した。乾熱加熱処理した大豆胚軸80k
gに熱水800kgを加え、98℃で10分間加熱抽出した。その
後、抽出液を分離し、残渣に熱水を800kgを加え再度98
℃で10分間加熱抽出した。ついで両抽出液を混合し、25
℃に冷却して、塩酸にてpH3.5に調整した後、10℃に冷
却し30分間保持した。その後連続遠心分離により不要物
を除去し、水酸化ナトリウムにて中和後、減圧濃縮、ス
プレー乾燥により酸性可溶抽出物、20kgを得た。表1に
乾燥固形分中の成分組成を示した。
<Production Example 2> (Preparation of acid-soluble extract from soybean hypocotyl) 80 kg of soybean hypocotyl was heated with a hot air at 140 ° C. using a gas roaster.
Dry heat treatment was performed for 0 minutes. Soybean hypocotyl 80k processed by dry heat treatment
800 kg of hot water was added to g, and the mixture was heated and extracted at 98 ° C for 10 minutes. After that, the extract is separated, and 800 kg of hot water is added to the residue, and 98
It was extracted by heating at 0 ° C for 10 minutes. Then both extracts were mixed and
After cooling to ℃ and adjusting to pH 3.5 with hydrochloric acid, it was cooled to 10 ℃ and kept for 30 minutes. Then, unnecessary substances were removed by continuous centrifugation, neutralized with sodium hydroxide, concentrated under reduced pressure and spray-dried to obtain 20 kg of an acidic soluble extract. Table 1 shows the component composition in the dry solid content.

【0027】<製造例3> (大豆ホエーの調製) 脱皮大豆に4倍量の90℃の熱水を加え、温度を80℃
以上に保ちつつ15分に一回程度弱い攪拌を加え2時間
浸漬して大豆ホエーを得た。
<Production Example 3> (Preparation of soybean whey) To dehulled soybeans, quadruple amount of hot water at 90 ° C was added, and the temperature was raised to 80 ° C.
While maintaining the above, weak stirring was added about once every 15 minutes, and the mixture was immersed for 2 hours to obtain soybean whey.

【0028】<製造例4> (乾熱加熱大豆胚軸の調
製) 大豆胚軸80kgをガスロースターを用いて140℃の熱風で2
0分間乾熱加熱処理し、乾熱加熱大豆胚軸を得た。表1
に乾燥固形分中の成分組成を示した。
<Production Example 4> (Preparation of dry-heat-heated soybean hypocotyl) 80 kg of soybean hypocotyl was heated with hot air at 140 ° C. for 2 times using a gas roaster.
Dry heat treatment was performed for 0 minutes to obtain dry heat soybean hypocotyls. Table 1
The composition of the dry solids is shown in Table 1.

【0029】 (表1) (単位:重量%) ───────────────────────────────── 組成 製造例1 製造例2 製造例3 製造例4 ───────────────────────────────── たん白質 20.4 15.4 9.4 42.1 脂質 0.9 0.4 0.1 9.9 灰分 6.8 12.7 15.9 4.4 炭水化物 71.8 71.5 74.6 43.7 イソフラボン 4.1 3.9 0.5 1.2 サポニン 12.4 2.0 0.8 2.1 オリゴ糖 15.8 14.1 27.2 8.7 ───────────────────────────────── *炭水化物=100−(たん白質+脂質+灰分)[0029] (Table 1) (Unit:% by weight) ──────────────────────────────────   Composition Production Example 1 Production Example 2 Production Example 3 Production Example 4 ──────────────────────────────────   Protein 20.4 15.4 9.4 42.1   Lipid 0.9 0.4 0.1 9.9   Ash 6.8 12.7 15.9 4.4   Carbohydrate 71.8 71.5 74.6 43.7   Isoflavone 4.1 3.9 0.5 1.2   Saponin 12.4 2.0 0.8 2.1   Oligosaccharide 15.8 14.1 27.2 8.7 ────────────────────────────────── * Carbohydrate = 100- (protein + lipid + ash)

【0030】<実施例1> (大豆胚軸茶の調製) 表2の配合にて大豆胚軸をガスロースターを用いて140
℃の熱風で20分間乾熱加熱処理した加熱大豆胚軸と、大
麦、緑茶を混合し茶葉とした。この茶葉10gに990gの水
を加え、98℃にて5分間撹拌抽出後、ろ布にて固液分離
行い、大豆胚軸茶を得た。本飲料の固形分は0.2重量%
であり、200mlを飲むと220mg相当の大豆胚軸水性抽出物
を摂取することができる。すなわち、イソフラボン9.0m
g、サポニン27.3mg、オリゴ糖34.8mgの有効成分の摂取
に相当する。本飲料中の大豆胚軸水性抽出物含量は乾燥
重量当り55重量%であった。
<Example 1> (Preparation of soybean hypocotyl tea) The soybean hypocotyls prepared according to the formulation shown in Table 2 were used with a gas roaster.
The heated soybean hypocotyl, which had been subjected to dry heat treatment with hot air at ℃ for 20 minutes, was mixed with barley and green tea to prepare tea leaves. To 10 g of this tea leaf was added 990 g of water, and the mixture was extracted with stirring at 98 ° C. for 5 minutes and then solid-liquid separated with a filter cloth to obtain soybean hypocotyl tea. The solid content of this beverage is 0.2% by weight
Therefore, if 200 ml is drunk, 220 mg of soybean hypocotyl aqueous extract can be ingested. That is, isoflavone 9.0m
Equivalent to ingestion of g, saponin 27.3mg, oligosaccharide 34.8mg active ingredient. The content of the soybean hypocotyl aqueous extract in this beverage was 55% by weight based on the dry weight.

【0031】 (表2) (単位:g) ─────────────── 原料 配合量 ─────────────── 加熱大豆胚軸 5.0 大麦 4.5 緑茶 0.5 水 990.0 ─────────────── 合計 1000.0 ───────────────[0031] (Table 2) (Unit: g) ─────────────── Raw material blending amount ─────────────── Heated soybean hypocotyl 5.0 Barley 4.5 Green tea 0.5 Water 990.0 ─────────────── Total 1000.0 ───────────────

【0032】<実施例2> (タブレットの調製) 製造例1にて得られた大豆胚軸水性抽出物を用い、表3
に示す配合で原料を混合し、造粒、打錠を経て大豆胚軸
水性抽出物を含有するタブレットを得た。本タブレット
3gを食することで大豆胚軸水性抽出物を240mgを摂取す
ることができる。すなわち、イソフラボン9.8mg、サポ
ニン29.8mg、オリゴ糖37.9mgの有効成分の摂取に相当す
る。本タブレット中の大豆胚軸水性抽出物含量は乾燥重
量当り約8重量%であった。
<Example 2> (Preparation of tablets) Using the soybean hypocotyl aqueous extract obtained in Production Example 1, Table 3
The raw materials were mixed in the formulation shown in (1) and granulated and compressed to give tablets containing the soybean hypocotyl aqueous extract. By eating 3 g of this tablet, 240 mg of the soybean hypocotyl aqueous extract can be ingested. That is, this corresponds to ingestion of the active ingredients of isoflavone 9.8 mg, saponin 29.8 mg, and oligosaccharide 37.9 mg. The content of the soybean hypocotyl aqueous extract in this tablet was about 8% by weight based on the dry weight.

【0033】 (表3) (単位:重量%) ───────────────── 原材料 配合率 ───────────────── 大豆胚軸水性抽出物 8.0 卵殻カルシウム 5.4 ブドウ糖 82.8 クエン酸 0.8 ショ糖脂肪酸エステル 2.5 香料 0.5 ───────────────── 合計 100.0 ─────────────────[0033] (Table 3) (Unit:% by weight) ───────────────── Raw material mix ratio ───────────────── Soybean hypocotyl aqueous extract 8.0 Eggshell calcium 5.4 Glucose 82.8 Citric acid 0.8 Sucrose fatty acid ester 2.5 Fragrance 0.5 ───────────────── Total 100.0 ─────────────────

【0034】<実施例3> (酸性飲料の調製) 製造例2にて得られた大豆胚軸酸性可溶抽出物を用い、
表4で示す組成で原料を混合、溶解後殺菌し、大豆胚軸
酸性可溶抽出物を配合する飲料を得た。この飲料はpH3.
7であり、固形分は10.1重量%であった。本酸性飲料200
gで大豆胚軸酸性可溶抽出物を200mg摂取することが出
来る。すなわち、イソフラボン7.8mg、サポニン4.0mg、
オリゴ糖28.2mgの有効成分の摂取に相当する。本酸性飲
料中の大豆胚軸水性抽出物含量は乾燥重量当り約1重量
%であった。
<Example 3> (Preparation of acidic beverage) Using the soybean hypocotyl acidic soluble extract obtained in Production Example 2,
Raw materials were mixed with the composition shown in Table 4, dissolved and sterilized to obtain a beverage containing the soybean hypocotyl acidic soluble extract. This beverage has a pH of 3.
7 and the solid content was 10.1% by weight. This acidic beverage 200
200 g of soybean hypocotyl acidic soluble extract can be ingested. That is, isoflavone 7.8 mg, saponin 4.0 mg,
Equivalent to ingestion of the active ingredient of 28.2 mg of oligosaccharide. The content of the aqueous extract of soybean hypocotyl in the acidic beverage was about 1% by weight based on the dry weight.

【0035】 (表4) (単位:重量%) ────────────────── 原材料 配合率 ────────────────── 大豆胚軸酸性可溶抽出物 0.1 グラニュー糖 10.0 クエン酸 0.4 ビタミンC 0.1 香料 0.25 水 89.15 ────────────────── 合計 100 ──────────────────[0035] (Table 4) (Unit:% by weight) ────────────────── Raw material mix ratio ────────────────── Soy hypocotyl acidic soluble extract 0.1 Granulated sugar 10.0 Citric acid 0.4 Vitamin C 0.1 Perfume 0.25 Water 89.15 ────────────────── Total 100 ──────────────────

【0036】<試験例1> (便秘改善効果の確認
1) 便秘症の被験者20名(21〜59才:平均年齢40才の女性、
被験前1週間の排便回数3回以下)に対し、実施例1で
調製した大豆胚軸茶1日600ml(大豆胚軸水性抽出物と
して660mg)を1ヶ月間飲用してもらった。有効成分の
摂取量はイソフラボン27.1mg、サポニン81.8mg、オリゴ
糖104.3mgに相当する。摂取前後の1週間あたりの排便
回数の変化についてアンケート調査を行った。結果を表
5に示した。
<Test Example 1> (Confirmation of Constipation Improvement Effect 1) 20 subjects with constipation (21 to 59 years old: women of average age 40 years,
For the number of bowel movements less than 3 times a week before the test 3 times or less), 600 ml of soybean hypocotyl tea prepared in Example 1 (660 mg as an aqueous extract of soybean hypocotyl) was drunk for 1 month. The intake of the active ingredient is equivalent to isoflavone 27.1 mg, saponin 81.8 mg, and oligosaccharide 104.3 mg. A questionnaire survey was conducted on changes in the number of bowel movements per week before and after ingestion. The results are shown in Table 5.

【0037】(表5) ──────────────── 排便回数の変化 人数 ──────────────── 排便回数が増加 15 名 排便回数変化なし 5 名 ────────────────(Table 5) ──────────────── Change in number of bowel movements ──────────────── Number of bowel movements increased 15 No change in defecation frequency 5 people ────────────────

【0038】<試験例2> (便秘改善効果の確認
2) 便秘症の被験者5名(46〜66才:平均年齢57才の女性、
被験前1週間の排便回数3回以下)に対し、実施例2で
調製したタブレットを1日3gずつ、6ヶ月間摂取して
もらった。この場合の有効成分の摂取量は1日あたりイ
ソフラボン9.4mg、サポニン4.8mg、オリゴ糖33.8mgに相
当する。摂食前後の排便回数の変化についてアンケート
調査行った。結果を表6に示した。
<Test Example 2> (Confirmation of Constipation Improvement Effect 2) 5 subjects with constipation (46-66 years old: female of average age 57 years old,
With respect to the number of bowel movements less than 3 times a week before the test (3 times or less), the tablets prepared in Example 2 were ingested 3 g / day for 6 months. In this case, the intake of the active ingredient is equivalent to 9.4 mg of isoflavone, 4.8 mg of saponin, and 33.8 mg of oligosaccharide per day. A questionnaire survey was conducted on changes in the frequency of defecation before and after eating. The results are shown in Table 6.

【0039】(表6) ──────────────── 排便回数の変化 人数 ──────────────── 排便回数が増加 5 名 排便回数変化なし 0 名 ────────────────(Table 6) ──────────────── Change in number of bowel movements ──────────────── Number of bowel movements increased 5 No change in defecation frequency 0 ────────────────

【0040】試験例1及び試験例2の結果より、本発明
の大豆胚軸由来の水性抽出物を含む組成物は便通改善に
対して有効であり、少量の摂取であっても優れた効果を
発揮した。
From the results of Test Example 1 and Test Example 2, the composition containing the aqueous extract derived from soybean hypocotyl of the present invention is effective for improving bowel movements, and even if it is ingested in a small amount, an excellent effect is obtained. Demonstrated.

【0041】<試験例3>製造例1にて得られた大豆胚
軸水性抽出物を用い、表7の配合1〜配合4に示す配合
率で原料を各々混合し、造粒、打錠を経てタブレットを
得た。
<Test Example 3> Using the soybean hypocotyl aqueous extract obtained in Production Example 1, the raw materials were mixed at the compounding ratios shown in Formulations 1 to 4 in Table 7, and granulated and tableted. After that, I got a tablet.

【0042】 (表7) (単位:重量%) ─────────────────────────────── 原材料 配合1 配合2 配合3 配合4 ─────────────────────────────── 大豆胚軸水性抽出物 − − 8.0 8.0 キシロオリゴ糖 20.0 − 20.0 − 有胞子乳酸菌 − 2.0 − 2.0 卵殻カルシウム 5.4 5.4 5.4 5.4 ブドウ糖 70.8 88.8 62.8 80.8 クエン酸 0.8 0.8 0.8 0.8 ショ糖脂肪酸エステル 2.5 2.5 2.5 2.5 香料 0.5 0.5 0.5 0.5 ─────────────────────────────── 合 計 100.0 100.0 100.0 100.0 ─────────────────────────────── ※有胞子乳酸菌は60億個/g含有するものを使用した。[0042] (Table 7) (Unit:% by weight) ───────────────────────────────   Raw materials Mix 1 Mix 2 Mix 3 Mix 4 ───────────────────────────────   Soybean hypocotyl aqueous extract − − 8.0 8.0   Xylooligosaccharide 20.0 − 20.0 −   Spore lactic acid bacteria-2.0-2.0   Eggshell calcium 5.4 5.4 5.4 5.4   Glucose 70.8 88.8 62.8 80.8   Citric acid 0.8 0.8 0.8 0.8   Sucrose fatty acid ester 2.5 2.5 2.5 2.5   Fragrance 0.5 0.5 0.5 0.5 ───────────────────────────────   Total 100.0 100.0 100.0 100.0 ───────────────────────────────   * We used spore lactic acid bacteria containing 6 billion cells / g.

【0043】便秘症の女性ボランティア(26〜35才:平
均年齢29才、1週間の排便回数3回以下)32名を各配合
ごとに8名に分け、試験例2と同様にタブレットを1日
3g摂取してもらい、摂取開始後4週間までの排便回数
の変化についてアンケート調査を行った。結果を表8に
示す。
32 female volunteers with constipation (26 to 35 years old: average age 29 years old, less than 3 times of defecation per week) were divided into 8 persons for each composition, and tablets were used for one day as in Test Example 2. 3 g was ingested, and a questionnaire survey was conducted on changes in the number of bowel movements up to 4 weeks after the start of ingestion. The results are shown in Table 8.

【0044】 (表8) (単位:人) ────────────────────────────── 週3回以下 週4〜5回 週6〜7回 ────────────────────────────── 2週間 配合1 2 3 3 配合2 1 3 4 配合3 0 1 7 配合4 0 2 6 ────────────────────────────── 4週間 配合1 1 3 4 配合2 0 2 6 配合3 0 0 8 配合4 0 0 8 ──────────────────────────────[0044] (Table 8) (Unit: people) ──────────────────────────────                     3 times a week or less 4-5 times a week 6-7 times a week ──────────────────────────────   2 weeks Formulation 1 2 3 3           Formula 2 1 3 4           Formula 3 0 1 7           Formulation 4 0 2 6 ──────────────────────────────   4 weeks Formulation 1 1 3 4           Formula 2 0 2 6           Formula 3 0 8           Formula 4 0 8 ──────────────────────────────

【0045】[0045]

【発明の効果】本発明により、食事療法や薬物投与によ
らず、微量でも便通の改善に優れた効果を発揮し、幅広
い飲食物に利用できる汎用性にも優れた便通改善用組成
物を提供することが可能となった。さらに、従来副産物
として大部分廃棄されていて、安価に入手できる大豆胚
軸を代表的な現代病である便秘症の改善する用途に利用
することが可能となり、食品産業・地球環境上非常に有
益となるものである。
EFFECTS OF THE INVENTION The present invention provides a composition for improving bowel movements, which exhibits excellent effects in improving bowel movements even in a small amount, regardless of diet therapy or drug administration, and can be used in a wide variety of foods and drinks, and has excellent versatility. It became possible to do. In addition, soybean hypocotyl, which has been mostly discarded as a by-product, can be used for the purpose of improving constipation, which is a typical modern disease, which is very beneficial to the food industry and the global environment. It will be.

───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.7 識別記号 FI テーマコート゛(参考) A61P 1/00 A61P 1/00 // A23L 1/30 A23L 1/30 B (72)発明者 橋本 征雄 大阪府泉佐野市住吉町1番地 不二製油株 式会社阪南事業所内 Fターム(参考) 4B018 LB04 MD58 ME11 4C084 AA17 MA02 MA52 ZA661 ZA731 4C086 AA01 AA02 BA08 EA01 EA10 MA01 MA04 MA52 NA14 ZA66 ZA73 4C088 AB59 AC04 BA09 BA12 BA13 BA14 CA05 MA52 NA14 ZA66 ZA73 ─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. 7 Identification code FI theme code (reference) A61P 1/00 A61P 1/00 // A23L 1/30 A23L 1/30 B (72) Inventor Masao Hashimoto Osaka 1 Sumiyoshi-cho, Izumisano, Japan Fuji Oil Co., Ltd. F-term in Hannan Works (Reference) 4B018 LB04 MD58 ME11 4C084 AA17 MA02 MA52 ZA661 ZA731 4C086 AA01 AA02 BA08 EA01 EA10 MA01 MA04 MA52 NA14 ZA66 ZA73 4C088 BA12 AC59 CA05 MA52 NA14 ZA66 ZA73

Claims (8)

【特許請求の範囲】[Claims] 【請求項1】大豆由来の水性抽出物を含有することを特
徴とする便通改善用組成物。
1. A composition for improving bowel movements, which comprises an aqueous extract derived from soybeans.
【請求項2】該水性抽出物に乾燥重量中イソフラボンが
0.3〜20重量%、サポニンが0.5〜30重量%が
含まれる請求項1に記載の便通改善用組成物。
2. The composition for improving bowel movements according to claim 1, wherein the aqueous extract contains isoflavone in an amount of 0.3 to 20% by weight and saponin in an amount of 0.5 to 30% by weight in a dry weight.
【請求項3】該水性抽出物に乾燥重量中オリゴ糖が5〜
40重量%含まれる請求項2に記載の便通改善用組成
物。
3. The aqueous extract contains 5 to 5 oligosaccharides in dry weight.
The composition for improving bowel movements according to claim 2, wherein the composition comprises 40% by weight.
【請求項4】該水性抽出物が大豆胚軸由来又は大豆ホエ
ー由来である請求項1〜3の何れかに記載の便通改善用
組成物。
4. The composition for improving bowel movements according to claim 1, wherein the aqueous extract is derived from soybean hypocotyl or soybean whey.
【請求項5】イソフラボン及びサポニンが重量換算で
0.3〜20:0.5〜30比率で含有する便通改善用
組成物。
5. A composition for improving bowel movement, which comprises isoflavone and saponin in a weight ratio of 0.3 to 20: 0.5 to 30.
【請求項6】イソフラボン、サポニン及びオリゴ糖が重
量換算で0.3〜20:0.5〜30比率で含有する便
通改善用組成物。
6. A composition for improving bowel movement, which comprises isoflavone, saponin, and oligosaccharide in a weight ratio of 0.3 to 20: 0.5 to 30.
【請求項7】オリゴ糖が大豆オリゴ糖である請求項3、
4又は6の何れかに記載の便通改善用組成物。
7. The oligosaccharide is soybean oligosaccharide, 3.
7. The composition for improving bowel movements according to 4 or 6.
【請求項8】整腸作用を示す原料をさらに含有する請求
項1〜7の何れかに記載の便通改善組成物。
8. The bowel movement-improving composition according to claim 1, further comprising a raw material having an intestinal regulating action.
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005018653A1 (en) * 2003-08-26 2005-03-03 Nihon Kefir Co., Ltd. Oral skin care composition
JP2006136246A (en) * 2004-11-12 2006-06-01 Nogyo Kagaku Kenkyusho:Kk Bowel movement-improving food or drink
JP2008105981A (en) * 2006-10-24 2008-05-08 Fuji Oil Co Ltd Composition of isoflavones
CN108245531A (en) * 2016-12-29 2018-07-06 鲁南制药集团股份有限公司 It is a kind of to improve gastrointestinal function, the anti-composition to treat constipation
CN110050925A (en) * 2019-04-22 2019-07-26 安吉艾格赛思生物科技有限公司 Intestinal microecology drinks and preparation method thereof are adjusted containing bamboo-leaves flavones

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005018653A1 (en) * 2003-08-26 2005-03-03 Nihon Kefir Co., Ltd. Oral skin care composition
JPWO2005018653A1 (en) * 2003-08-26 2007-11-01 日本ケフィア株式会社 Internal composition for skin care
JP5048246B2 (en) * 2003-08-26 2012-10-17 日本ケフィア株式会社 Internal composition for skin care
JP2006136246A (en) * 2004-11-12 2006-06-01 Nogyo Kagaku Kenkyusho:Kk Bowel movement-improving food or drink
JP2008105981A (en) * 2006-10-24 2008-05-08 Fuji Oil Co Ltd Composition of isoflavones
CN108245531A (en) * 2016-12-29 2018-07-06 鲁南制药集团股份有限公司 It is a kind of to improve gastrointestinal function, the anti-composition to treat constipation
CN110050925A (en) * 2019-04-22 2019-07-26 安吉艾格赛思生物科技有限公司 Intestinal microecology drinks and preparation method thereof are adjusted containing bamboo-leaves flavones

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