JP2003070799A - Braided fabric - Google Patents

Braided fabric

Info

Publication number
JP2003070799A
JP2003070799A JP2001269171A JP2001269171A JP2003070799A JP 2003070799 A JP2003070799 A JP 2003070799A JP 2001269171 A JP2001269171 A JP 2001269171A JP 2001269171 A JP2001269171 A JP 2001269171A JP 2003070799 A JP2003070799 A JP 2003070799A
Authority
JP
Japan
Prior art keywords
fiber
knitted fabric
surface portion
woven
dimensional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001269171A
Other languages
Japanese (ja)
Inventor
Tadayuki Sakobe
唯行 迫部
Masahiko Miwa
正彦 三和
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unitika Fibers Ltd
Unitika Technos Co Ltd
Original Assignee
Unitika Fibers Ltd
Unitika Technos Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unitika Fibers Ltd, Unitika Technos Co Ltd filed Critical Unitika Fibers Ltd
Priority to JP2001269171A priority Critical patent/JP2003070799A/en
Publication of JP2003070799A publication Critical patent/JP2003070799A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/82—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin for bone cerclage
    • A61B17/826—Nets or webs

Abstract

PROBLEM TO BE SOLVED: To provide a new medical material which is gradually degraded and finally absorbed in a human body, made of a material finally absorbed in a human body, has a prescribed gaps therein, can be arbitrarily adjusted in thickness corresponding to a symptom, and is useful for operation of hip joint fracture as footing for regeneration of cartilage tissue cells. SOLUTION: This is stereoscopic medical braided fabric constituted of a structure comprising a surface part, a backside part, and a connection part. All three parts are made of biodegradable fiber comprising aliphatic polyester such as poly-butyric acid fiber, etc.

Description

【発明の詳細な説明】Detailed Description of the Invention

【０００１】[0001]

【発明の属する技術分野】本発明は、医療分野において
体内に埋め込まれる材料として使用される立体織編物に
関するものである。TECHNICAL FIELD The present invention relates to a three-dimensional woven or knitted fabric used as a material to be embedded in the body in the medical field.

【０００２】[0002]

【従来の技術】従来、股関節等の骨折手術には、ポリエ
チレン等のプラスチック製の固定材や金属製の固定材、
あるいは骨セメント等の接着剤が使用されている。しか
しプラスチック製固定材や金属製固定材では最終的にそ
の固定材の除去手術が必要となり、また臨床応用されて
いるプレート、ねじ及びピン等は生体骨に比べて弾性が
大きすぎるため骨組織が脆弱化したり、金属溶出による
生体損傷等の問題も残されている。また骨セメント等の
接着剤による接着では副作用と見られる急激な血圧低下
などが懸念される。2. Description of the Related Art Conventionally, for bone fracture surgery such as hip joints, a plastic fixing material such as polyethylene or a metal fixing material,
Alternatively, an adhesive such as bone cement is used. However, plastic fixing materials and metal fixing materials eventually require surgery to remove the fixing material, and clinically applied plates, screws, pins, etc. have too large elasticity compared to living bones, so bone tissue is There are still problems such as weakening and biological damage due to metal elution. In addition, there is a concern that an adhesive agent such as bone cement may cause a sudden drop in blood pressure, which is considered to be a side effect.

【０００３】そこでゆっくり分解し最終的に体内に吸収
される性質を有する新医療用材料が提案されつつある。
例えば、ポリ乳酸をリボン状に編んだもの等が、骨折等
の手術で有用であること等が動物実験で実証されている
（日本経済新聞、1997.2.15）。この方法は、リボン状
に編まれた材料を組織細胞再生の足場として利用する方
法である。しかしリボン状に編まれた材料では空隙（隙
間）がなく、骨髄細胞、軟骨細胞や肝細胞等の組織細胞
等の活着が表面上にあるためにポリ乳酸が生体内に吸収
される速度が遅くなるだけでなく、損傷部位の快復も遅
くなることが懸念されるという問題があった。また特に
軟骨や関節を負傷した際にはリボン状の材料ではクッシ
ョン性がないため、完治するまで伴う痛みが激しいもの
であった。Therefore, a new medical material having a property of slowly decomposing and finally being absorbed into the body is being proposed.
For example, it has been demonstrated in animal experiments that polylactic acid knitted into a ribbon is useful in surgery such as bone fracture (Nikkei, 1997.2.15). This method is a method of using a material knitted in a ribbon shape as a scaffold for tissue cell regeneration. However, the material woven in the form of ribbon does not have voids, and the rate of absorption of polylactic acid into the body is slow due to the presence of bone marrow cells, tissue cells such as chondrocytes and hepatocytes on the surface. In addition to the above, there is a concern that recovery of the damaged part may be delayed. Further, when the cartilage or the joint is injured, the ribbon-shaped material does not have a cushioning property, so that the pain accompanied by complete healing is severe.

【０００４】[0004]

【発明が解決しようとする課題】本発明は、この様な現
状に鑑みて行われたもので、最終的に生体内に吸収され
る材料で一定の空隙を有し、その症状により厚みを任意
に調節できる材料を提供することを目的とするものであ
る。SUMMARY OF THE INVENTION The present invention has been made in view of such a situation as described above, and it is a material that is finally absorbed in the living body and has a certain void. The purpose of the present invention is to provide a material which can be adjusted.

【０００５】[0005]

【課題を解決するための手段】本発明は、上記の目的を
達成するものであり、表面部、裏面部及び連結部の三層
からなる立体構造を有する立体織編物であって、各部が
生分解性を有する繊維で構成されていることを特徴とす
る医療用立体織編物、生分解性を有する繊維が脂肪族ポ
リエステルからなる繊維であることを特徴とする上記の
医療用立体織編物、及び生分解性を有する繊維がポリ乳
酸系繊維であることを特徴とする上記の医療用立体織編
物を要旨とするものである。The present invention achieves the above object, and is a three-dimensional woven or knitted fabric having a three-dimensional structure consisting of a front surface portion, a back surface portion and a connecting portion, each portion being a raw material. Medical three-dimensional knitted fabric characterized by being composed of degradable fibers, the above-mentioned medical three-dimensional knitted fabric characterized in that the biodegradable fiber is a fiber made of an aliphatic polyester, and The gist of the above-mentioned medical three-dimensional woven or knitted fabric is characterized in that the biodegradable fiber is a polylactic acid-based fiber.

【０００６】[0006]

【発明の実施の形態】以下、本発明について詳細に説明
する。本発明の医療用立体織編物は、表面部、裏面部及
び連結部の三層からなる立体構造を有している。すなわ
ち表面部を形成する地組織と裏面部を形成する地組織と
が、連結部を形成する糸条で連結された立体構造を有す
る織物あるいは編物である。表面部の地組織と裏面部の
地組織は、いずれも織物や編物で用いられる組織であれ
ばいずれでもよく、これらは同一の組織であっても、異
なる組織であってもよい。また厚さとしては、使用する
部位や症状によりそれに適した厚さのものを選定すれば
よいが、表面部と裏面部の間の間隙を有効に利用すると
の観点から１ｍｍ以上あるものが好ましく、１０mm位ま
でのものが使用される。BEST MODE FOR CARRYING OUT THE INVENTION The present invention will be described in detail below. The medical three-dimensional woven or knitted fabric of the present invention has a three-dimensional structure including three layers, a front surface portion, a back surface portion, and a connecting portion. That is, it is a woven or knitted fabric having a three-dimensional structure in which the ground structure forming the front surface portion and the ground structure forming the back surface portion are connected by the yarns forming the connecting portion. The ground structure of the front surface part and the ground structure of the back surface part may be any structures as long as they are used in woven or knitted fabrics, and they may be the same structure or different structures. The thickness may be selected depending on the site to be used and symptoms, but it is preferably 1 mm or more from the viewpoint of effectively utilizing the gap between the front surface portion and the back surface portion. Those up to about 10 mm are used.

【０００７】このような立体織編物の製造方法として
は、両面丸編機、ダブルトリコット編機、ダヅルラッセ
ル編機等の２列の針床を有する編機や、モケット織機を
利用して３層構造とする方法が挙げられる。これらの中
でも、２列の針床を有する編機による編物は、比較的伸
縮性もあり、骨組織や体内に及ぼす影響が少ないと考慮
されるためより好ましい材料である。As a method for producing such a three-dimensional woven or knitted fabric, a knitting machine having two rows of needle beds such as a double-sided circular knitting machine, a double tricot knitting machine, a dazzle russel knitting machine, or a moquette loom is used to form a three-layer structure. There is a method of doing. Among these, a knitted fabric with a knitting machine having two rows of needle beds is a more preferable material because it is considered to be relatively stretchable and has little influence on bone tissue and the body.

【０００８】本発明の立体織編物は、表面部、裏面部及
び連結部の各部を構成する繊維として、生分解性を有す
る繊維が使用されている。本発明において生分解性を有
する繊維とは、生分解性物質から構成される繊維をい
う。生分解性物質とは、微生物により直接主として水と
二酸化炭素に分解されるもの、あるいは加熱等によるか
水分解等の予備的分解を経た後に微生物により主として
水と二酸化炭素に分解されるものをいい、例えば、JIS
K 6950、JIS K 6951、JIS K 6953等の生分解性試験にお
ける生分解度百分率の最高レベルが６０％以上を示す物
質が挙げられる。このような物質の具体的な例として
は、ポリ乳酸、ポリカプロラクトン、ポリブチレンサク
シネート、ポリエチレンサクシネート、ポリグリコール
酸等の脂肪族ポリエステル、該脂肪族系ポリエステルと
芳香族系ポリエステルの共重合体、ポリビニルアルコー
ル、ポリアミノ酸類、ポリアミド類、セルロース及びそ
の誘導体、澱粉、酢酸セルロースおよび綿や絹等が挙げ
られ、またこれらの複合物等であってもよい。In the three-dimensional woven or knitted fabric of the present invention, biodegradable fibers are used as the fibers constituting the front surface portion, the back surface portion and the connecting portion. In the present invention, the biodegradable fiber refers to a fiber composed of a biodegradable substance. The biodegradable substance means a substance that is directly decomposed into water and carbon dioxide by microorganisms, or a substance that is mainly decomposed into water and carbon dioxide by microorganisms after preliminary decomposition such as heating or water decomposition. , For example, JIS
Examples of such substances include K 6950, JIS K 6951, and JIS K 6953, which have a maximum level of biodegradability of 60% or more in a biodegradability test. Specific examples of such substances include aliphatic polyesters such as polylactic acid, polycaprolactone, polybutylene succinate, polyethylene succinate, and polyglycolic acid, and copolymers of the aliphatic polyester and aromatic polyester. , Polyvinyl alcohol, polyamino acids, polyamides, cellulose and its derivatives, starch, cellulose acetate, cotton, silk, and the like, and may be a composite of these.

【０００９】これらの中でも、コスト面、製編織性、ま
た弾力性を調整する上で、脂肪族ポリエステル系の繊維
を用いるのが好ましく、また生体内分解速度が半年から
１年間であるポリ乳酸繊維を用いるのが最も好ましい。Among these, it is preferable to use an aliphatic polyester fiber from the viewpoint of adjusting cost, knitting and weaving properties, and elasticity, and polylactic acid fiber having a biodegradation rate of half a year to one year. Is most preferably used.

【００１０】その繊維形態についても、特に制限するも
のではなく、紡績糸、長繊維糸またモノフィラメントを
使用することができ、繊維状態で混紡、混繊等の手法に
より複数の繊維が混用されていてもよい。また表面部、
裏面部及び連結部の三層の各部位についてもそれぞれ必
要度合いに応じて異なる繊維を使用すること、もしくは
繊維形態の異なるものを使用することもできる。The fiber form is also not particularly limited, and spun yarn, long fiber yarn or monofilament can be used, and a plurality of fibers are mixed by a method such as mixed spinning or mixed fiber in a fiber state. Good. Also the surface part,
It is also possible to use different fibers for each of the three layers of the back surface portion and the connection portion, or to use different fiber shapes depending on the degree of need.

【００１１】上記のように本発明の立体織編物は、生分
解性を有する繊維で構成されているが、必要に応じてよ
り生体適合性のある物質を繊維上もしくは織編物に付与
することもできる。使用可能な生体適合性のある物質と
しては、例えばコラーゲン、キチンやポリアミノ酸等が
挙げられる。As described above, the three-dimensional woven or knitted fabric of the present invention is composed of biodegradable fibers. However, if necessary, a more biocompatible substance may be applied onto the fibers or the woven or knitted fabric. it can. Examples of biocompatible substances that can be used include collagen, chitin and polyamino acids.

【００１２】[0012]

【作用】本発明の立体織編物のように表面部、裏面部及
び連結部の三層からなる立体構造を有することにより、
一定の空隙を有し、その症状により厚みを任意に調節で
き、各部分が生分解性を有する繊維で構成されていて、
最終的に生体内に吸収されるので、軟骨組織細胞等の再
生の足場として利用するのに適した医療用材料とするこ
とができる。The three-dimensional woven or knitted fabric of the present invention has a three-dimensional structure consisting of a front surface portion, a back surface portion and a connecting portion.
It has a certain void, the thickness can be adjusted arbitrarily depending on the symptom, and each part is composed of biodegradable fibers,
Since it is finally absorbed in the living body, it can be a medical material suitable for use as a scaffold for regeneration of cartilage tissue cells and the like.

【００１３】[0013]

【実施例】次に、本発明を実施例により具体的に説明す
る。 実施例１ カールマイヤー社製ダブルラッセル編機（１８ゲージ）
により、図１に示す編組織で、筬Ｌ1から筬Ｌ6の各筬に
８４デシテックス／３６フィラメントのポリ乳酸長繊維
糸を給糸して編成し、表面部、裏面部及び連結部が共に
ポリ乳酸長繊維糸からなり、厚さが５ｍｍである本発明
の医療用立体構造ダブルラッセル編物を得た。得られた
ダブルラッセル編物を、健常な雑種成犬の切断した肋骨
髄内に挿入固定後、経時的に取り出し接合部を観察し
た。術後６ヶ月で、本発明のダブルラッセル編物は隣接
した骨髄組織と非常に良く密着し、材料境界部の骨形成
が良好であって、骨結合材として優れていることが確認
された。本発明と比較するために、８４デシテックス／
３６フィラメントのポリ乳酸長繊維糸からなる平組織で
幅5mmのリボン状織物とステンレスピンを用いて、平行
して観察したところ、リボン状織物は術後９ヶ月で材料
境界部の骨形成が確認されたが、本発明品と比較して骨
形成部の速度が若干の遅いものであり、ステンレスピン
ではクリアーゾーンが認められ骨新生がかなり遅延して
いることが確認された。EXAMPLES Next, the present invention will be specifically described by way of examples. Example 1 Double Russell knitting machine (18 gauge) manufactured by KARL MAYER
Thus, in the knitting structure shown in FIG. 1, polylactic acid long fiber yarn of 84 decitex / 36 filament is fed to each reed L 1 to reed L 6 and knitted, and the front surface portion, the back surface portion and the connecting portion are both A three-dimensional medical double-raschel knitted fabric of the present invention, which was made of polylactic acid long fiber yarn and had a thickness of 5 mm, was obtained. The obtained double Russell knitted fabric was inserted and fixed in the cut rib bone marrow of a healthy mongrel dog, and then taken out with time to observe the joint. Six months after the operation, it was confirmed that the double Russell knitted fabric of the present invention adhered very well to the adjacent bone marrow tissue, had good bone formation at the material boundary portion, and was excellent as a bone bonding material. For comparison with the present invention, 84 decitex /
Using a ribbon-like woven fabric with a width of 5 mm and a stainless steel pin consisting of a 36-filament polylactic acid long-fiber yarn, the ribbon-shaped woven fabric confirmed bone formation at the material boundary 9 months after surgery. However, the speed of the bone formation part was slightly slower than that of the product of the present invention, and it was confirmed that a clear zone was observed in the stainless steel pin and that bone formation was considerably delayed.

【００１４】[0014]

【発明の効果】本発明によると、本発明の医療用立体織
編物は、表面部、裏面部及び連結部の三層構造からなる
立体織編物であって、各部分が生分解性を有する繊維で
構成されていて、一定の空隙を有し、その症状により厚
みを任意に調節でき、最終的に生体内に吸収される材料
でできているので、軟骨組織細胞等の再生の足場として
利用するのに適した医療用材料を提供することができ
る。According to the present invention, the three-dimensional woven or knitted article for medical use of the present invention is a three-dimensional woven or knitted article having a three-layer structure of a front surface portion, a back surface portion and a connecting portion, and each portion is biodegradable Since it is made of a material that has a certain amount of voids, its thickness can be adjusted arbitrarily according to its symptoms, and is finally absorbed into the body, it is used as a scaffold for regeneration of cartilage tissue cells and the like. It is possible to provide a medical material suitable for

【図面の簡単な説明】[Brief description of drawings]

【図1】実施例にて用いた立体編地の編成組織図であ
る。FIG. 1 is a knitting organization chart of a three-dimensional knitted fabric used in an example.

───────────────────────────────────────────────────── フロントページの続き Ｆターム(参考） 4C060 LL13 4C081 BA16 CA171 DA04 DC04   ─────────────────────────────────────────────────── ─── Continued front page    F-term (reference) 4C060 LL13                 4C081 BA16 CA171 DA04 DC04

Claims (3)

【特許請求の範囲】[Claims] 【請求項１】 表面部、裏面部及び連結部の三層からな
る立体構造を有する立体織編物であって、各部が生分解
性を有する繊維で構成されていることを特徴とする医療
用立体織編物。1. A three-dimensional woven or knitted fabric having a three-dimensional structure consisting of a front surface portion, a back surface portion and a connecting portion, wherein each portion is composed of biodegradable fibers. Woven and knitted fabric. 【請求項２】 生分解性を有する繊維が脂肪族ポリエス
テルからなる繊維であることを特徴とする請求項１記載
の医療用立体織編物。2. The medical three-dimensional woven or knitted fabric according to claim 1, wherein the biodegradable fiber is a fiber made of an aliphatic polyester. 【請求項３】 生分解性を有する繊維がポリ乳酸系繊維
であることを特徴とする請求項１記載の医療用立体織編
物。3. The medical three-dimensional woven or knitted fabric according to claim 1, wherein the biodegradable fiber is a polylactic acid-based fiber.
JP2001269171A 2001-09-05 2001-09-05 Braided fabric Pending JP2003070799A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2001269171A JP2003070799A (en) 2001-09-05 2001-09-05 Braided fabric

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2001269171A JP2003070799A (en) 2001-09-05 2001-09-05 Braided fabric

Publications (1)

Publication Number Publication Date
JP2003070799A true JP2003070799A (en) 2003-03-11

Family

ID=19095036

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001269171A Pending JP2003070799A (en) 2001-09-05 2001-09-05 Braided fabric

Country Status (1)

Country Link
JP (1) JP2003070799A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005018698A1 (en) * 2003-08-20 2005-03-03 Bioretec Oy Porous medical device and method for its manufacture
WO2018052059A1 (en) * 2016-09-15 2018-03-22 国立大学法人神戸大学 Spacer for radiation therapy

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005018698A1 (en) * 2003-08-20 2005-03-03 Bioretec Oy Porous medical device and method for its manufacture
WO2018052059A1 (en) * 2016-09-15 2018-03-22 国立大学法人神戸大学 Spacer for radiation therapy

Similar Documents

Publication Publication Date Title
US20230218380A1 (en) Prosthesis Comprising a Three-Dimensional and Openworked Knit
US6737371B1 (en) Hernia implant, method for its manufacture and use in surgery
JP5405482B2 (en) Implants for parastomal hernia
EP2293752B1 (en) Wound dressing
EP2345430B1 (en) A reinforced absorbable multilayered fabric for use in medical devices and method of manufacture
CN102056634B (en) Quilted implantable graft
Zhang et al. Application of knitting structure textiles in medical areas
US9308068B2 (en) Implant for parastomal hernia
JP2011505220A5 (en)
JP5721379B2 (en) Suture reinforcement material for automatic suturing device containing hydrophilic polymer
BRPI0621587A2 (en) reinforced and absorbable multilayer fabric for use in medical devices and manufacturing method
CN101687057A (en) Reparation that is used to organize or regenerated composite device
JP2003070799A (en) Braided fabric
US20190144618A1 (en) Method for preparing a chitosan-based matrix comprising a fiber reinforcement member
Afzal et al. Fibres for medical textiles
AU2014203792B2 (en) Implant for parastomal hernia
JP7329384B2 (en) tissue regeneration substrate