JP2002531596A - Novel alkanolamide-free thickening latex - Google Patents

Abstract

  (57) [Summary] Oil phase, aqueous phase, at least one water-in-oil (W / O) emulsion, at least one oil-in-water (O / W) emulsion and 20 to 75% by weight, mainly 20 to 60% by weight A method for preparing a composition in the form of a reversed-phase latex, in particular comprising 30 to 45% by weight of a branched or crosslinked anionic polyelectrolyte, wherein the polymerization reaction is carried out at a pH of less than 5.5 and the emulsifier is an alkanol Not belonging to the amide family, the anionic polyelectrolyte comprises a strong acid functional group copolymerized with either a monomer containing a strong acid function or at least one monomer containing a weak acid function or at least one neutral monomer. A method characterized in that it is based on any of at least one monomer. The resulting composition and application to cosmetics.

Description

DETAILED DESCRIPTION OF THE INVENTION

The present application relates to a novel process for water-in-oil latexes and their use as thickeners and / or emulsifiers for skin care and hair care products or for the manufacture of cosmetics, skin preparations or formulation preparations Regarding the application of latex.

[0002] Among the various existing thickeners used for their purpose, in particular,
There is an inverse latex, a synthetic thickening polymer that exists in the form of a latex in which the continuous phase is oily. The latex dissolves extremely quickly. The polymer contained in the reverse phase latex is, for example, a sodium acrylamide / 2-acrylamido-2-methylpropanesulfonate copolymer. It is already neutralized and it is observed that the pH is generally greater than 6 when it is dissolved in water, for example to a concentration of 1%. Such reversed-phase latexes are disclosed in European patent applications published under EP0186361 and EP0503853. These latexes retain significant thickening ability even at pH 4.

However, methods for preparing such copolymers use surfactants of the alkanolamide family such as, for example, Witcamide® 511. Here, those compounds tend to decompose into compounds of the nitrosamine family, which are products known per se to be potentially carcinogenic. Thus, the simple implementation of the precautionary principle makes it unavoidable, in the short or long term, that the reversed-phase latex is banned for use in the preparation of cosmetics, dermatological or pharmaceutical products. Therefore, the Applicant has been interested in developing new methods for synthesizing reversed-phase latexes that do not have this disadvantage.

[0004] One subject of the invention is:-step (a) of preparing an aqueous solution comprising the monomers and optional additives,-preparation in step (a) in the presence of one or more water-in-oil emulsifiers (B) emulsifying the resulting aqueous phase in an organic phase, (c) polymerizing the monomers in the aqueous phase, initiated by adding a free radical initiator to the aqueous phase, and Continuously adding (d) one or more oil-in-water type emulsifiers at a temperature of less than 50 ° C., wherein at least one water-in-oil (W / O) emulsifier, One oil-in-water (O / W) emulsifier and from 20% by weight to 75%
A process for preparing a composition in the form of a reversed-phase latex comprising, by weight, mainly from 20% to 60% by weight, in particular from 30% to 45% by weight, of a branched or crosslinked anionic polyelectrolyte, -The polymerization reaction in step (c) is carried out at a pH of less than 5.5,-none of the emulsifiers belong to the alkanolamide family, and-the anionic polyelectrolyte is a monomer containing a strong acid function, or A method characterized by being based on either at least one monomer containing a strong acid functional group copolymerized with at least one monomer containing a weak acid functional group or with at least one neutral monomer.

According to one variant of this method, the reaction mixture obtained in step (b)
It is concentrated by distillation before carrying out c).

According to one preferred embodiment of the method as defined above, the polymerization reaction is carried out below 10 ° C., if desired, supplemented with a polymerization co-initiator such as, for example, azobis (isobutyronitrile) (AIBN). At a temperature of cumene hydroperoxide / sodium disulfite (N
a ₂ S ₂ O ₅ ) couple or cumene hydroperoxide / thionyl chloride (SO
Initiated by a redox couple that generates bisulfite ions (HSO ₃ ⁻ ), such as a Cl ₂ ) couple, then substantially adiabatically or controlling the temperature to temperatures above 50 ° C. It is performed either by the following.

[0007] The term "alkanolamide" refers to the product resulting from the reaction of an alkanolamine, such as, for example, mono- or diethanolamine, with an equimolar amount of a fatty acid.

[0008] The expression "water-in-oil emulsifier" has the name Hypermer (Hypermer;
Surfactant polymer sold under the trade name Montane (registered trademark) 80 or sorbitan monooleate sold by the company SEPPIC under the trade name Montane® 80 or SEPPI under the name Montene® 70, for example.
C represents an emulsifier having an HLB value low enough to give a water-in-oil emulsion such as a sorbitan extract (extract) such as sorbitan isostearate sold by C.

The expression “oil-in-water emulsifier” refers to an HLB high enough to give an oil-in-water emulsion such as an ethoxylated sorbitan ester such as sorbitan oleate ethoxylated with 20 moles of ethylene oxide. Represents an emulsifier having a value.

[0010] The term "branched polymer" refers to a non-linear chain that includes a pendant chain that results in a highly entangled state that results in very high viscosity at low shear when the polymer is dissolved in water. Represents a polymer.

The term “cross-linked polymer” refers to a non-linear polymer in the form of a three-dimensional network that is insoluble in water but swellable in water, thus producing a chemical gel. The composition obtained by the method as defined above may comprise a cross-linking part and / or a branch part.

The subject of the present invention is in particular that the anionic polyelectrolyte comprises 30% to 80%, preferably 30% to 60%, by mole ratio of monomeric moieties containing strong acid functions, in particular anionic polyelectrolytes. The method as defined above, wherein the electrolyte comprises 30% to 50% of a monomer containing a strong acid function and 70% to 50% of either a monomer containing a weak acid function or a neutral monomer.

The strong acid function in the monomer comprising a strong acid function is in particular a sulfonic acid function or a phosphonic acid function, said monomer preferably being 2-methyl-2-
[(1-oxo-2-propenyl) -amino] -1-propanesulfonic acid. The weak acid function in the monomer containing a weak acid function is in particular a carboxylic acid function, said monomer preferably being selected from acrylic acid, methacrylic acid, itaconic acid and maleic acid. Neutral monomers are in particular acrylamide, 2-hydroxyethyl acrylate, 2,3-dihydroxyethyl acrylate, 2-
1 to 20 EO for each of hydroxyethyl methacrylate, 2,3-dihydroxyethyl methacrylate or ethoxylated derivative ester
It is selected from ethoxylated derivatives having a number.

The subject of the invention is, in particular, that the anionic polyelectrolyte has a molar ratio of 30% to 50%.
% Of 2-methyl-2-[(1-oxo-) partially or fully salified in the form of an alkali metal salt, preferably the sodium salt, or in the form of an ammonium salt.
2-propenyl) amino] -1-propanesulfonic acid and 70% to 50% acrylamide.

The subject of the invention is in particular a cross-linking of the anionic polyelectrolyte with a molar ratio of 0.005% to 1%, preferably 0.01% to 0.1% of diethylene or polyethylene compounds relative to the monomers used. And / or branched, characterized in that the crosslinker and / or branching agent is chosen in particular from ethylene glycol methacrylate, sodium diallyloxyacetate, ethylene glycol diacrylate, diallyl urea, trimethylolpropane triacrylate and, in particular, methylenebisacrylamide. This is the method defined above.

The latex obtained by the process according to the invention generally comprises from 2.5% to 15% by weight, preferably from 4% to 9% by weight, of the emulsifier, in which the total amount of emulsifier present 20% to 50%, especially 25% to 40% by weight of water in oil (W /
O) type, 80% to 50%, especially 75% to 60% of the total weight of the emulsifier
% Are of the oil-in-water (O / W) type.

According to one particular aspect of the above defined method, the water-in-oil emulsifier consists essentially of sorbitan monooleate.

According to another particular aspect, the composition obtained by the method as defined above is characterized in that the oily phase is between 15% and 40%, preferably between 20% and 25% of its total weight. I do. This oil phase may be, for example, Exsol sold by Exxon (Ex
xsol) D 100 S or Marcol® 52
Including paraffinic, isoparaffinic or cycloparaffinic type hydrocarbons having a density at room temperature of 0.7 to 0.9 and a boiling point above 180 ° C., such as white mineral oil such as isohexadecane or isododecane sold by Bayer Consisting of any of the commercially available mineral oils, or vegetable oils, or synthetic oils, or several mixtures of these oils.

According to one preferred aspect of the present invention, the composition obtained by the method as defined above is characterized in that the oily phase consists essentially of isohexadecane or Marcol® 52. The isohexadecane identified in the chemical abstract by RN number = 93685-80-4 is a mixture of C ₁₂ , C ₁₆ and C ₂₀ isoparaffins containing at least 97% of C ₁₆ isoparaffins, wherein the major constituents are , 2,2,4,4.6,8,8-heptamethylnonane (RN =
4390-04-9). Marcol® 52 is a commercially available oil that complies with the French Codex definition of liquid petroleum. It is a white mineral oil according to FDA regulations 21 CFR 172.878 and CFR 178.3620 (a) and is registered in the United States Pharmacopeia as US XXIII (1995) and in the European Pharmacopoeia (1993).

The latex contains 20% to 50% water. The latex according to the invention can also be used as a complexing agent, a transfer agent.
agent) or a chain-limiting agent.
And various additives such as

The subject of the present invention is also the use of a composition obtained by a method as defined above for preparing a cosmetic, dermatological or pharmaceutical topical composition.

A topical composition according to the invention intended to be applied to the skin or mucous membranes of humans or animals consists of a topical emulsion comprising at least one aqueous phase and at least one oil phase. sell. This topical emulsion may be of the oil-in-water type. In particular, this topic (topic
al) Emulsions may consist of fluid emulsions such as emulsions or fluid gels. The oil phase of the topical emulsion may consist of a mixture of one or more oils.

The topical emulsions according to the invention can be used for preparing medical products intended for cosmetic use or for treating skin and mucous membrane disorders. In the latter case, the topical composition then comprises the active ingredient which may consist of, for example, an anti-inflammatory, muscle relaxant, fungicide or antibacterial agent.

When the topical composition is used as a cosmetic composition intended to be applied to the skin or mucous membranes, it may, for example, be a humectant, a sunscreen, a sunscreen, a wrinkle remover, a mucous agent, It may or may not contain active ingredients such as free radical scavengers, anti-acne or fungicides.

The topical compositions according to the invention usually contain from 0.1 to 10% by weight of a thickener as defined above. The pH of the topical composition is preferably 5 or more, more preferably 6
Or 12.

The topical composition may also include compounds conventionally included in this type of composition such as, for example, fragrances, preservatives, colorings, emollients or surfactants.

According to yet another aspect, the present invention relates to the use of a novel thickener according to the invention as described above for thickening and emulsifying a topical composition comprising at least one aqueous phase.

A cosmetic, dermatological or pharmaceutical composition as defined above generally comprises from 0.1% to 10% by weight, in particular from 0.5% to 5% by weight, of said reverse-phase latex. It is present in particular in the form of emulsions, lotions, gels, creams, cream gels, soaps, bubble baths, balms, shampoos or conditioners.

In general, the reversed-phase latex is advantageously sold by the applicant in cosmetics, skin preparations or pharmaceutical compositions under the name Sepigel® 305 or Sepigel® 501. Product. It also has good compatibility with other additives used for the preparation of formulations such as emulsions, lotions, creams, soaps, foaming baths, balms, shampoos and conditioners. It can also be used in combination with the Sepigel product.

It is especially mentioned in WO 92/06778, WO 95/04592, WO 9
Compatible with the concentrates disclosed in 5/13863, WO 98/47610 and FR 2 733 496 and the surfactants disclosed in WO 93/08204.

It is in particular the case of Montanov (registered trademark) 68, Montanov (
® 82, Montanov ® 202, and Sepipearl
perl®N compatible. It is also disclosed in the type of emulsions disclosed and claimed in EP 0 629 396 and for example W
It can also be used in cosmetically or physiologically acceptable aqueous dispersions with a polyorganosiloxane compound selected from those disclosed in WO 93/05762 or WO 93/21316. It is also described in WO 93/07856
Can also be used to form a cosmetically or physiologically acceptable aqueous gel at acidic pH such as those disclosed in US Pat. It is also, for example, EP0
EP0603019 in combination with, or instead of, nonionic cellulose to form a styling gel such as that disclosed in US Pat.
WO92 / 2, in combination with or instead of fatty acid esters of sugars to form compositions for treating hair or skin such as those disclosed in
Carbopo for forming a hair treatment product such as that disclosed in DE 195 23 596, or finally in a shampoo or conditioner disclosed and claimed in US Pat.
l; registered trademark). It is also compatible with many active ingredients, such as, for example, dihydroxyacetone (DHA) or acne, for example, self-tanning agents. It can therefore be introduced into self-tanning compositions such as those claimed in EP 0 715 845, EP 0 604 249, EP 0 576 188 or WO 93/07902. It can also be found in WO92 / 21318, WO94 / 2756
Also compatible with N-acyl amino acid derivatives which allow their use in sedative compositions, especially for sensitive skin, such as those disclosed and claimed in WO 98/09611. It also includes glycolic acid, lactic acid, salicylic acid, retinoids, phenoxyethanol, sugars, glyceraldehyde,
It is also compatible with xanthan, fruit acid and various polyols used in the manufacture of cosmetic formulations.

Thus, a subject of the invention is also the use of a reversed-phase latex as defined above for preparing a cosmetic, dermatological or pharmaceutical composition.

[0033] The examples described below are intended to illustrate the invention, but are not intended to limit the invention.

Example 1 Preparation of a Latex According to the Invention a) The following are placed in a beaker with stirring:-80 g of deionized water;-95.96 g of a 48% (by weight) aqueous sodium hydroxide solution;-246. 7 g of 2-methyl-2-[(1-oxo-2-propenyl) amino] -1-propanesulfonic acid, -253.8 g of 50% acrylamide, -0.45 g of sodium diethylenetriaminepentaacetate, -0.132 g Methylene bis (acrylamide).

The pH of the aqueous phase is adjusted to about 5.0 and the amount of the aqueous phase is made up to 682 g by adding deionized water. In parallel, the organic phase is prepared by continuously introducing the following into a stirred beaker: 220 g of isohexadecane, 21 g of Montene® 80 VG (sorbitan sold by SEPPIC Oleate), 0.2 g AIBN.

[0036] The aqueous phase is gradually introduced into the organic phase and then the ultra phase sold by IKA.
The mixture is subjected to strong mechanical agitation using an Ultra-Turrax® mixer.

Next, the obtained emulsion is transferred to a polymerization reactor. The emulsion is foamed with a strong stream of nitrogen to remove oxygen and cooled to about 5-6C.

Then, 5 ml of an isohexadecane solution containing 0.28% (by weight) cumene hydroperoxide is added.

After a sufficient time for good homogenization of the solution, an aqueous sodium disulfite solution (1
2.5 g) in 00 ml of water is then added at a rate of 0.5 ml / min. The addition is performed over about 60 minutes. During this addition, the temperature in the polymerization reactor is allowed to rise to the final polymerization temperature.

The reaction medium is then maintained at this temperature for about 90 minutes.

The mixture is cooled to a temperature of about 35 ° C. and 50 g of sorbitan oleate ethoxylated with 20 mol of ethylene oxide are slowly added.

The desired emulsion is obtained. Evaluation of properties Viscosity increase in water containing 2% latex (Brookfield RVT spindle 6, speed 20): 23450 mPa · s (Brookfield spindle 6, speed 5): η = 69000 mPa · s
.

B) The process described above in paragraph a) is repeated and isohexadecane is converted to Marcol® to prepare a latex based on white mineral oil.
Replace with 52.

The examples described below use any one of the emulsions prepared in Example 1.

Example 2: Care Cream Cyclomethicone: 10% Composition 1: 0.8% Montanov® 68: 2% Stearyl Alcohol: 1% Stealic alcohol: 0.5% Preservative : 0.65% Lysine: 0.025% EDTA (disodium salt): 0.05% Xanthan gum: 0.2% Glycerol: 3% Water: balance (qs) 100% Example 3: Care cream Cyclomethicone: 10 % Composition 1: 0.8% Montanov® 68: 2% Perfluoropolymethylisopropyl ether: 0.5% Stearyl alcohol: 1% Stearic alcohol: 0.5% Preservative: 0.65% Lysine: 0.025% EDTA (disodium salt): 0.05% Pemulen (registered trademark) R: 0.2% glycerol: 3% Water: balance 100% Example 4: After Shave Balm (Oil after shaving) Formulation composition A Composition 1: 1.5% Water: balance 100% B Micropearl (registered trademark) M100: 5.0% Sepicide® CI: 0.50% Fragrance: 0.20% 95 ° Ethanol: 10.0% Procedure Add B to A.

Example 5: Satin Body Emulsion Formulation Composition A Simulsol® 165: 5.0% Lanol® 1688: 8.50% Callite butter: 2% Liquid paraffin: 6.5% Lanol (registered) TM) 14M: 3% Lanol® S: 0.6% B Moisture: 66.2% C Micropearl® M100: 5% D Composition 1: 3% E Sepiside® CI: 0.3% Sepiside (registered trademark) HB: 0.5% Montein (registered trademark) CA: 1% Fragrance: 0.20% Vitamin E acetate: 0.20% Pyrrolidinone carboxylate sodium salt: 1% (humectant Procedure) Add C to B, emulsify B in A at 70 ° C, then add D at 60 ° C, then add E at 30 ° C.

Example 6: Body Emulsion Formulation Composition A Simulsol® 165: 5.0% Lanol® 1688: 12.0% Lanol® 14M: 2.0% Cetyl alcohol: 0.1% 3% Shellsemol (registered trademark) OP: 3% B Moisture: balance 100% C Composition 1: 0.35% D Sepiside (registered trademark) CI: 0.2% Sepiside (registered trademark) HB: 0.5 % Fragrance: 0.20% Procedure Emulsify B in A at about 75 ° C, add C at about 60 ° C, then add D at about 30 ° C.

Example 7: O / W cream Formulation composition A Simulsol® 165: 5.0% Lanol® 1688: 20.0% Lanol® P: 1.0% (stabilizing effect B Moisture: 100% balance C Composition 1: 2.50% D Sepiside (R) CI 0.20% Sepiside (R) HB 0.30% Procedure at about 75 ° C to A B is introduced. C is added at about 60 ° C, followed by D at about 45 ° C.

Example 8: Non-Grease Sunscreen Gel Formulation Composition A Composition 1: 3.00% Moisture: 30% B Sepiside® CI: 0.20% Sepiside® HB: 0.30% Fragrance: 0.10% C Colorant: appropriate amount Water: 30% D Micropearl (registered trademark) M100: 3.00% Water: balance 100% E Silicone oil: 2.0% Parsol (registered trademark) MCX: 5 0.000% Procedure Introduce B into A, add C, then D, then E.

Example 9: Sunscreen emulsion Formulation composition A Sepipearl® N: 3.0% Sesame oil: 5.0% Parsol® MCX: 5.0% λ Carrageenan: 0.10% B Water: Composition 100: 0.80% D Perfume: Appropriate amount Preservative: Appropriate amount Procedure Emulsify B in A at 75 ° C, then add C at about 60 ° C, then add about 30 ° C. Add D and, if necessary, adjust the pH.

Example 10: Massage Gel Formulation Composition A Composition 1: 3.5% Water: 20.0% B Colorant: 2 drops / 100 g Water: Suitable amount C Alcohol: 10% Menthol: 0.10% D Silicone Oil: 5.0% Procedure Add B to A, then add C to the mixture, followed by D.

Example 11: Massage Care Gel Formulation Composition A Composition 1: 3.00% Moisture: 30% B Sepiside® CI: 0.20% Sepiside® HB: 0.30% Fragrance: 0 0.05% C Colorant: Suitable amount Moisture: 100% balance D Micropearl® SQL: 5.00% Lanol® 1688: 2% Procedure A is prepared, B then C is added, followed by Add D.

Example 12: Facial Matting Gel Formulation Composition A Composition 14 4% Water: 30% B Elastin HPM: 5.0% C Micropearl® M100: 3% Water: 5% D Sepiside® ) CL: 0.2% Sepicide® HB: 0.3% Fragrance: 0.06% 50% Sodium pyrrolidinone carboxylate 1% Water: balance 100% Procedure A is prepared, B then C is added, followed by And add D.

Example 13: Body Emulsion Formulation Composition A Sepipearl® N: 3.0% Glyceryl triheptonate: 10.0% B Water: balance 100% C Composition 1: 1.0% D Fragrance: Appropriate amount Preservative: Appropriate amount Procedure Melt A at about 75 ° C. Emulsify B in A at 75 ° C and then at about 60 ° C
, Followed by D.

Example 14: Cosmetic removal emulsion containing sweet almond oil Formulation composition Montanov® 68: 5% Sweet almond oil: 5% Moisture: balance 100% Composition 1: 0.3% glycerol: 5% preservative Ingredient: 0.2% Fragrance: 0.3% Example 15: Moisturizing cream for greasy skin Formulation composition Montanoff® 68: 5% Cetylstearyl octanoate: 8% Octyl palmitate: 2% Moisture: Composition 1: 0.6% Micropearl® M100: 3.0% Mucopolysaccharide: 5% Sepiside® HB: 0.8% Fragrance: 0.3% Example 16: No alcohol Additive sedative aftershave balm Formulation composition Mixture of lauryl amino acids: 0.1% to 5% Magnesium aspartate Lithium: 0.002% to 0.5% Lanol® 99: 2% Sweet almond oil: 0.5% Water: 100% balance Composition 1: 3% Sepiside® HB: 0.3% Sepicide® CI: 0.2% Fragrance: 0.4% Example 17: Cream with AHA for sensitive skin Formulation composition Mixture of lauryl amino acids: 0.1% to 5% Potassium magnesium aspartate: 0.002% to 0.5% Lanol® 99: 2% Montanov® 68: 5.0% Moisture: 100% balance Composition 1: 1.50% Gluconic acid: 1.50% triethylamine : 0.9% Sepicide (registered trademark) HB: 0.3% Sepicide (registered trademark) CI: 0.2% Fragrance: 0.4% Example 18: Sedative after sunburn A Formulation composition Mixture of lauryl amino acids: 0.1% to 5% Magnesium potassium aspartate: 0.002% to 0.5% Lanol® 99: 10.0% Water: balance 100% Composition 1: 2.50% Sepiside (registered trademark) HB: 0.3% Sepiside (registered trademark) CI: 0.2% Fragrance: 0.4% Colorant: 0.03% Example 19: Emulsion for removing makeup Formulation composition Sepipearl ( (Registered trademark) N: 3% Primol (registered trademark) 352: 8.0% sweet almond oil: 2% water: balance 100% Composition 1: 0.8% preservative: 0.2% Example 20: body emulsion Formulation composition Sepipearl (registered trademark) N: 3.5% Lanol (registered trademark) 37T: 8.0% Soragam (registered trademark) L: 0.05% Water content: balance 100% Benzofu Non: 2.0% Dimethicone 350 cPs: 0.05% Composition 1: 0.8% Preservatives: 0.2% Fragrance: 0.4% Example 21: Fluid emulsion at alkaline pH Malcol® 82: 5 NaOH: 10.0% Moisture: 100% balance Composition 1: 1.5% Example 22: Fluid foundation Formulation composition Simulsol® 165: 5.0% Lanol® 84D: 8. 0% Lanol® 99: 5.0% Water: balance 100% Inorganic pigments and fillers: 10.0% Composition 1: 1.2% Preservatives: 0.2% Fragrance: 0.4% Example 23 : Sunscreen emulsion Formulation composition Sepipearl (registered trademark) N: 3.5% Lanol (registered trademark) 37T: 10.0% Parsol Knox (registered trademark): 5.0% Euzolex (registered trademark) Trademark) 4360: 2.0% Moisture: 100% balance Composition 1: 1.8% Preservative: 0.2% Fragrance: 0.4% Example 24: Eyelid cosmetic gel Formulation composition Composition 1: 2.0 Perfume: 0.06% Sodium pyrrolidinone carboxylate: 0.2% Dow Corning® 245 fluid: 2.0% Moisture: 100% balance Example 25: Leave on care composition Formulation composition Composition 1 : 1.5% Fragrance: proper amount Preservative: proper amount Dow Corning (R) X2 8360: 5.0% Dow Corning (R) Q2 1401: 15% Water: balance 100% Example 26: mucilage gel composition Material 1: 5% Ethanol: 30% Menthol: 0.1% Caffeine: 2.5% Ruscus extract: 2% Ivy extract: 2% Sepiside® HP : 1% Moisture: balance 100% Example 27: Alcohol-free aftershave balm for sedation Formulation composition A Lipaside (registered trademark) PVB: 1.0% Lanol (registered trademark) 99: 2.0% Sweet almond oil: 0.5 % B Composition 1: 3.5% C Moisture: balance 100% D Fragrance: 0.4% Sepiside (registered trademark) HB: 0.4% Sepiside (registered trademark) CI: 0.2% Example 28: Refreshing After Shave Gel Formulation Composition A Lipaside (registered trademark) PVB: 0.5% Lanol (registered trademark) 99: 5.0% Composition 1: 2.5% B Water: balance 100% C Micropearl (registered trademark) LM: 0.5% Fragrance: 0.2% Sepicide® HB: 0.3% Sepicide® CI: 0.2% Example 29: For oily skin A Product Formulation composition A Micropearl (registered trademark) M310: 1.0% Composition 1: 5.0% Octyl isononanoate: 4.0% B Water: 100% balance C Sepicontrol (registered trademark) A5: 4 0.0% Perfume: 0.1% Sepiside® HB: 0.3% Sepiside® CI: 0.2% Kapigel® 98: 0.5% Water: 10% Example 30: AHA A. Montanoff (registered trademark) 68: 5.0% Lipaside (registered trademark) PVB: 1.05% Lanol (registered trademark) 99: 10.0% B Water: balance 100% gluconic acid: 1. 5% TEA (triethylamine): 0.9% C Composition 1: 1.5% D Fragrance: 0.4% Sepiside® HB: 0.2% Sepiside® CI: Example 31: Non-greasy self-tanning agent for face and body Formulation composition A Lanol® 2681: 3.0% Composition 1: 2.5% B Moisture: balance 100% Dihydroxyacetone: 3 0.0% C Fragrance: 0.2% Sepicide (registered trademark) HB: 0.8% NaOH (sodium hydroxide): An appropriate amount so as to have a pH of 5 Example 32: Sunscreen emulsion containing Tahitian monoi (monoi) Formulation Composition A Tahitian monoi: 10% Lipaside (registered trademark) PVB: 0.5% Composition 1: 2.2% B Water: balance 100% C Fragrance: 0.1% Sepiside (registered trademark) HB: 0.3% Sepicide® CI: 0.1% Octyl methoxycinnamate: 4.0% Example 33: Sunscreen care for the face Formulation composition A Cyclomethicone and dimethicone Nol: 4.0% Composition 1: 3.5% B Moisture: balance 100% C Fragrance: 0.1% Sepiside (registered trademark) HB: 0.3% Sepiside (registered trademark) CI: 0.21% octyl Methoxycinnamate: 5.0% Titanium mica: 2.0% Lactic acid: an appropriate amount so as to have a pH of 6.5 Example 34: Self-tanning emulsion Formulation composition A Lanol (registered trademark) 99: 15% Montanov (registered trademark) ) 68: 5.0% octyl paramethoxycinnamate: 3.0% B Water: balance 100% Dihydroxyacetone: 5.0% monosodium phosphate: 0.2% C Composition 1: 0.5% D perfume : 0.3% Sepiside (registered trademark) HB: 0.8% NaOH: appropriate amount so that pH = 5 Montanov (registered trademark) 68 (cetearyl glucoside) is obtained from SEP A self-emulsifying composition disclosed in WO 92/06778 sold by PIC.

Micropearl® M100 is an ultrafine powder sold by Matsumo with an extremely soft feel and matte effect.

Sepiside® CI, imidazoline urea, is a SEPPIC
Preservative sold by the company.

[0058] Pemren® TR is an acrylic polymer sold by Goodrich.

Simulsol® 165 is a self-emulsifying glyceryl stearate sold by SEPPIC.

[0060] Lanol® 1688 is a non-greasy emollient ester sold by the company SEPPIC.

Lanol® 14M and Lanol® S are available from SEPPIC
Is a consistency factor sold by the company.

Sepicide® HB, which is a mixture of phenoxyethanol, methylparaben, ethylparaben, propylparaben and butylparaben, is
A preservative sold by IC Company.

Montane® CA is a humectant sold by SEPPIC.

Shellsemol® OP is a non-greasy emollient ester.

[0065] Lanol® P is a stabilizing additive sold by the company SEPPIC.

[0066] Parsol® MCX is octyl paramethoxy cinnamate sold by Givaudan.

Sepipearl® N is a nacreous agent sold by the company SEPPIC based on a mixture of alkyl polyglucosides such as those disclosed in WO 95/13863.

Micropearl® SQL is a mixture of microparticles containing squalane that is released by the action of a massage. It is sold by Matsumo.

[0069] Lanol® 99 is isononyl isononanoate sold by the company SEPPIC.

Ranol 37T is glyceryl triheptanoate sold by SEPPIC.

Soragam® L is a carrageenan sold by the company SEPPIC.

[0072] Marcol® 82 is a liquid paraffin sold by Esso.

Lanol® 84D is dioctyl malate (dioctyl malate) sold by SEPPIC.

[0074] Parsol Knox® is a sunscreen sold by Givaudan.

Euzolex® 4360 is a sunscreen sold by Merck.

[0076] Dow Corning® 245 Fluid is a cyclomethicone sold by Dow Corning.

[0077] Lipaside® PVB is a palmitoylated wheat protein hydrolyzate sold by the company SEPPIC.

Micropearl® LM is a mixture of squalane, polymethyl methacrylate and menthol sold by the company SEPPIC.

SepiControl® A5 is a SEPI control such as that disclosed in International Patent Application No. PCT / FR98 / 01313 filed on June 23, 1998.
It is a mixture of capryloyl glycine, sarcosine and extract of Cinnamon zylanicum sold by PPIC.

[0080] Kapigel® 98 is an acrylate copolymer sold by the company SEPPIC.

Lanol® 2681 is a mixture of caprylate and coconut caprylate sold by SEPPIC.

Montanov® 202 is available from WO 98 sold by the company SEPPIC.
/ 47610.

[Procedural Amendment] Submission of translation of Article 34 Amendment

[Submission date] December 8, 2000 (2000.12.8)

[Procedure amendment 1]

[Document name to be amended] Statement

[Correction target item name] Claims

[Correction method] Change

[Correction contents]

[Claims]

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI theme coat ゛ (Reference) A61K 7/02 A61K 7/02 A 7/021 7/021 7/032 7/032 7/42 7/42 7/48 7/48 C08F 220/56 C08F 220/56 // (C08F 220/56 (C08F 220/56 220: 54) C08F 220: 54) (72) Inventor Tabacy, Guy France, F-81100 Castre , Ryu Becquerel 11 F term (reference) 4C083 AA122 AA161 AB032 AB242 AB282 AC01 AC022 AC072 AC102 AC122 AC172 AC212 AC242 AC302 AC332 AC342 AC352 AC372 AC422 AC441 AC482 AC532 AC582 AC852 AD022 AD071 AD092 AD152 AD172 AD212 AD352 AD412 AD532 CC33 CC38 DD08 DD21 DD31 DD41 FF01 4J011 AA05 AA09 AB02 AB08 BA03 BB01 BB02 BB09 DA01 LA04 LA06 LA07 LB02 LB03 LB05 LB07 LB10 4J100 AM14Q AM15P BA56Q CA04 DA38 FA20 FA27 JA60 JA61

Claims (13)

[Claims] 1. A step (a) of preparing an aqueous solution containing a monomer and optional additives;-the aqueous phase prepared in step (a) in the presence of one or more water-in-oil emulsifiers (B) emulsifying in the organic phase, (c) initiating the free-radical initiator into the aqueous phase to polymerize the monomers in the aqueous phase, and (D) adding one or more oil-in-water emulsifiers at a temperature of at least one oil-phase, water-phase, water-in-oil (W / O) emulsifier, oil-in-water ( In the form of a reversed-phase latex comprising at least one emulsifier of the O / W) type and from 20 to 75% by weight, mainly from 20 to 60% by weight, in particular from 30 to 45% by weight, of branched or crosslinked anionic polyelectrolytes A method of preparing a composition, comprising: The polymerization reaction in step a) is carried out at a pH of less than 5.5,-none of the emulsifiers belong to the alkanolamide group,-the anionic polyelectrolyte comprises a monomer containing a strong acid function, or a weak acid function. A method characterized in that it is based on any of at least one monomer comprising a strong acid functional group copolymerized with either at least one monomer comprising or at least one neutral monomer. 2. The process according to claim 1, wherein the reaction mixture obtained from step (b) is concentrated by distillation before carrying out step (c). 3. The polymerization reaction, if desired, is azobis (isobutyronitrile).
Supplemented by a polymerization coinitiator such as (AIBN), at a temperature of 10 ° C. or less, a cumene hydroperoxide / sodium disulfite (Na ₂ S ₂ O ₅ ) couple or a cumene hydroperoxide / thionyl chloride (SOCl ₂ ) couple bisulfite ions such as (HSO ₃ ^-) the method of claim 1 or 2 starts with a redox couple for generating. 4. The monomer part contained in the anionic polyelectrolyte in a molar ratio of 30
% To 80%, preferably 30% to 60%, contain strong acid functions, in particular, the anionic polyelectrolyte contains 30% to 50% monomers containing strong acid functions and 70%
4. The method according to claim 1, wherein the method comprises any of a monomer containing from 1 to 50% of a weak acid function or a neutral monomer. 5. An anionic polyelectrolyte in a molar ratio of 30% to 50% of partially or totally salted alkali metal salts, preferably sodium or ammonium salts. 5. The method of claim 4 comprising methyl-2-[(1-oxo-2-propenyl) amino] -1-propanesulfonic acid and 70% to 50% acrylamide. 6. The anionic polyelectrolyte is crosslinked and / or crosslinked by a diethylene or polyethylene compound in a molar ratio to the monomers used of from 0.005% to 1%, preferably from 0.01% to 0.1%. 6. The method according to claim 1, wherein the method is branched. 7. The cross-linking and / or branching agent is selected from ethylene glycol methacrylate, sodium diallyloxyacetate, ethylene glycol diacrylate, diallyl urea, trimethylolpropane triacrylate, and especially methylene bis (acrylamide). 7. The method of claim 6, wherein: 8. The method according to claim 1, wherein the water-in-oil emulsifier used consists essentially of sorbitan monooleate. 9. The oily phase comprises from 15% to 40% of the total weight, preferably from 20% to 2%.
9. The method according to claim 1, wherein the amount is 5%. 10. The process as claimed in claim 1, wherein the oily phase comprises isohexadecane or white mineral oil. 11. Use of a composition obtained by the method according to any one of claims 1 to 10 for preparing a cosmetic, dermatological or pharmaceutical topical composition. 12. A cosmetic, dermatological or pharmaceutical composition comprising from 0.1 to 10% by weight of a reversed-phase latex obtained by the method according to any one of claims 1 to 10. 13. The composition according to claim 12, in the form of a lotion, gel, cream gel, cream, soap, foam bath, balm, shampoo or conditioner.