JP2002335964A5 - - Google Patents
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- JP2002335964A5 JP2002335964A5 JP2001131638A JP2001131638A JP2002335964A5 JP 2002335964 A5 JP2002335964 A5 JP 2002335964A5 JP 2001131638 A JP2001131638 A JP 2001131638A JP 2001131638 A JP2001131638 A JP 2001131638A JP 2002335964 A5 JP2002335964 A5 JP 2002335964A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- partial peptide
- amide
- ester
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000003839 salts Chemical class 0.000 description 13
- 239000011780 sodium chloride Substances 0.000 description 13
- 102000004169 proteins and genes Human genes 0.000 description 8
- 108090000623 proteins and genes Proteins 0.000 description 8
- 229920003013 deoxyribonucleic acid Polymers 0.000 description 7
- 150000001408 amides Chemical class 0.000 description 6
- 150000002148 esters Chemical class 0.000 description 6
- 102000004965 antibodies Human genes 0.000 description 3
- 108090001123 antibodies Proteins 0.000 description 3
- 125000003275 alpha amino acid group Chemical group 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000032 diagnostic agent Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
Description
【特許請求の範囲】
【請求項１】
配列番号：４で表されるアミノ酸配列と同一もしくは実質的に同一のアミノ酸配列を含有することを特徴とするタンパク質またはその塩。
【請求項２】
請求項１記載のタンパク質の部分ペプチドもしくはそのアミドもしくはそのエステルまたはその塩。
【請求項３】
請求項１記載のタンパク質をコードするＤＮＡを含有するＤＮＡ。
【請求項４】
配列番号：３で表わされる塩基配列を有する請求項３記載のＤＮＡ。
【請求項５】
請求項２記載の部分ペプチドをコードするＤＮＡを含有するＤＮＡ。
【請求項６】
請求項３または請求項５記載のＤＮＡを含有する組換えベクター。
【請求項７】
請求項６記載の組換えベクターで形質転換された形質転換体。
【請求項８】
請求項７記載の形質転換体を培養し、請求項１記載のタンパク質または請求項２記載の部分ペプチドを生成せしめることを特徴とする請求項１記載のタンパク質もしくはその塩、または請求項２記載の部分ペプチドもしくはそのアミドもしくはそのエステルまたはその塩の製造法。
【請求項９】
請求項１記載のタンパク質もしくはその塩、または請求項２記載の部分ペプチドもしくはそのアミドもしくはそのエステルまたはその塩に対する抗体。
【請求項１０】
請求項３もしくは請求項５記載のＤＮＡまたは請求項９記載の抗体を含有してなる診断剤。
【請求項１１】
請求項１記載のタンパク質もしくはその塩、または請求項２記載の部分ペプチドもしくはそのアミドもしくはそのエステルまたはその塩あるいは請求項９記載の抗体を含有してなる医薬。
【請求項１２】
癌の予防・治療剤である請求項１１記載の医薬。
【請求項１３】
請求項１記載のタンパク質もしくはその塩、または請求項２記載の部分ペプチドもしくはそのアミドもしくはそのエステルまたはその塩を含有してなる請求項１記載のタンパク質もしくはその塩、または請求項２記載の部分ペプチドもしくはそのアミドもしくはそのエステルまたはその塩の活性を促進または阻害する化合物またはその塩のスクリーニング用キット。
[Claims]
(1)
A protein or a salt thereof comprising an amino acid sequence identical or substantially identical to the amino acid sequence represented by SEQ ID NO: 4.
(2)
A partial peptide of the protein according to claim 1, or an amide or ester thereof, or a salt thereof.
(3)
A DNA containing the DNA encoding the protein according to claim 1.
(4)
4. The DNA according to claim 3, which has the base sequence represented by SEQ ID NO: 3.
(5)
A DNA containing a DNA encoding the partial peptide according to claim 2.
6.
A recombinant vector containing the DNA according to claim 3 or 5.
7.
A transformant transformed with the recombinant vector according to claim 6.
Claim 8.
The protein according to claim 1 or a salt thereof, or the salt according to claim 2, wherein the transformant according to claim 7 is cultured to produce the protein according to claim 1 or the partial peptide according to claim 2. A method for producing a partial peptide, an amide thereof, an ester thereof, or a salt thereof.
9.
An antibody against the protein according to claim 1 or a salt thereof, or the partial peptide according to claim 2 or an amide or ester thereof or a salt thereof.
10.
A diagnostic agent comprising the DNA according to claim 3 or 5, or the antibody according to claim 9.
11.
A pharmaceutical comprising the protein according to claim 1 or a salt thereof, the partial peptide according to claim 2, or an amide or ester thereof or a salt thereof, or the antibody according to claim 9.
12.
The medicament according to claim 11, which is an agent for preventing or treating cancer.
Claim 13
The protein according to claim 1, or a salt thereof, or the partial peptide according to claim 1, which comprises the partial peptide according to claim 2, an amide thereof, an ester thereof, or a salt thereof. Alternatively, a kit for screening a compound or a salt thereof that promotes or inhibits the activity of an amide or an ester or a salt thereof.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001131638A JP2002335964A (en) | 2000-04-27 | 2001-04-27 | New protein and application thereof |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000127547 | 2000-04-27 | ||
| JP2000-127547 | 2000-04-27 | ||
| JP2001064862 | 2001-03-08 | ||
| JP2001-64862 | 2001-03-08 | ||
| JP2001131638A JP2002335964A (en) | 2000-04-27 | 2001-04-27 | New protein and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002335964A JP2002335964A (en) | 2002-11-26 |
| JP2002335964A5 true JP2002335964A5 (en) | 2008-06-05 |
Family
ID=27343222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001131638A Pending JP2002335964A (en) | 2000-04-27 | 2001-04-27 | New protein and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2002335964A (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8555798A (en) * | 1997-08-01 | 1999-02-22 | Genset | 5' ests for secreted proteins expressed in muscle and other mesodermal tissues |
| WO1999031236A2 (en) * | 1997-12-17 | 1999-06-24 | Genset | EXTENDED cDNAs FOR SECRETED PROTEINS |
| CA2296792A1 (en) * | 1999-02-26 | 2000-08-26 | Genset S.A. | Expressed sequence tags and encoded human proteins |
| CA2391455A1 (en) * | 1999-12-01 | 2001-06-07 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
-
2001
- 2001-04-27 JP JP2001131638A patent/JP2002335964A/en active Pending
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