JP2002325845A - Drug solution injector suitable for small volume of drug solution dosing - Google Patents

Drug solution injector suitable for small volume of drug solution dosing

Info

Publication number
JP2002325845A
JP2002325845A JP2001135913A JP2001135913A JP2002325845A JP 2002325845 A JP2002325845 A JP 2002325845A JP 2001135913 A JP2001135913 A JP 2001135913A JP 2001135913 A JP2001135913 A JP 2001135913A JP 2002325845 A JP2002325845 A JP 2002325845A
Authority
JP
Japan
Prior art keywords
gasket
drug solution
cylindrical body
outlet
inlet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001135913A
Other languages
Japanese (ja)
Other versions
JP3973854B2 (en
Inventor
Mitsuru Hasegawa
長谷川  満
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nipro Corp
Fujifilm RI Pharma Co Ltd
Original Assignee
Nipro Corp
Fujifilm RI Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nipro Corp, Fujifilm RI Pharma Co Ltd filed Critical Nipro Corp
Priority to JP2001135913A priority Critical patent/JP3973854B2/en
Priority to US10/097,485 priority patent/US6929620B2/en
Priority to EP20020005392 priority patent/EP1243280B1/en
Priority to DE60232388T priority patent/DE60232388D1/en
Publication of JP2002325845A publication Critical patent/JP2002325845A/en
Priority to US11/142,442 priority patent/US7351229B2/en
Application granted granted Critical
Publication of JP3973854B2 publication Critical patent/JP3973854B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Abstract

PROBLEM TO BE SOLVED: To provide a drug solution injector which is easily operable and can dose a small volume of other drug solution midway drug solution dosing. SOLUTION: The inlet 13 and the outlet 14 are equipped on both sides mutually opposite with respect to the longitudinal axis on the cylindrical body 1. Gaskets 2, 3 are tightly in contact with each other and a drug solution chamber 5 is equipped in between gaskets 3, 4. On the base end of the gasket 2, both ends of the gasket 3, and the tip end of the gasket 4, cylindrical projections 21, 31, 32, 41 with outer diameters smaller than the inner diameter of the cylindrical body 1 are equipped. The gasket 2 is movable from a position to communicate the inlet 13 with the outlet 14 for drug solution to the tip end 11 of the cylindrical body 1 via the cylindrical projection parts 21, 31. The inlet 13 for drug solution is opened to the lumen of the cylindrical body 1 to the tip end side than the outlet 14 so that the inlet 13 and the outlet 14 for drug solution communicate with each other via the cylindrical projection parts 32, 41 when the gasket 2 is moved to the tip end 11 of the cylindrical body 1.

Description

【発明の詳細な説明】DETAILED DESCRIPTION OF THE INVENTION

【0001】[0001]

【発明の属する技術分野】本発明は、プライミング操作
から連続した操作で少量の薬液を投与するのに好適な薬
液注入器に関する。本発明の薬液注入記は、薬液投与の
途中で別の薬液を投与する場合や、抗癌剤など混注操作
に際して操作者が汚染される虞のある薬剤の投与に好適
である。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a liquid injector suitable for administering a small amount of liquid by a continuous operation from a priming operation. The drug solution injection according to the present invention is suitable for the case where another drug solution is administered in the middle of the drug solution administration, or for the administration of a drug such as an anticancer drug which may contaminate the operator during a co-injection operation.

【0002】[0002]

【従来の技術】輸液セットやカテーテルを使用して行う
薬液投与に際して、薬液投与の途中で別の薬液の投与を
必要とすることがよくある。例えば、造影剤や、ホルモ
ン製剤、ペプチド製剤、抗癌剤、ビタミン剤等の場合で
あり、薬液が予め充填された注射器、所謂プレフィルド
シリンジを使用して行われることが多い。従来、このよ
うな混注を必要とする場合、三方活栓やY字管を使用し
て流路を切り換えることにより行っていた。
2. Description of the Related Art When administering a drug solution using an infusion set or a catheter, it is often necessary to administer another drug solution during the administration of the drug solution. For example, it is a case of a contrast agent, a hormone preparation, a peptide preparation, an anticancer drug, a vitamin preparation, etc., and is often performed using a syringe filled with a drug solution in advance, a so-called pre-filled syringe. Conventionally, when such co-injection is required, it has been performed by switching the flow path using a three-way cock or a Y-tube.

【0003】しかしながら、このような三方活栓やY字
管を使用した混注の場合、プレフィルドシリンジの接続
操作やプライミングの際に、中に収容された薬液が外部
に漏れる虞があり、特に抗癌剤など発ガン性の高い製剤
を混注する場合には、操作者の健康上問題がある。ま
た、高価な薬液を少量投与する場合、操作が煩雑であ
り、他の薬液と混合して濃度が希薄になり効果的な投与
が出来なかったり、残液があるなどの問題もあった。
However, in the case of such co-injection using a three-way cock or a Y-shaped tube, there is a risk that the drug solution contained therein may leak to the outside during the connection operation or priming of the pre-filled syringe, and in particular, the release of an anticancer agent or the like. In the case of co-injecting a preparation having a high cancer-causing property, there is a problem in operator's health. In addition, when a small amount of an expensive drug solution is administered, the operation is complicated, and the solution is mixed with another drug solution, so that the concentration becomes diluted, so that there is a problem that an effective administration cannot be performed or there is a residual solution.

【0004】[0004]

【発明が解決しようとする課題】本発明は、如上の事情
に鑑みてなされたもので、操作が簡単で、薬液投与の途
中で少量の別の薬液を連続的に投与することが出来る薬
液注入器を提供することを目的とする。
DISCLOSURE OF THE INVENTION The present invention has been made in view of the above circumstances, and is simple in operation and capable of continuously administering a small amount of another chemical during the administration of the chemical. The purpose is to provide a vessel.

【0005】[0005]

【課題を解決するための手段】本発明者は上記課題を解
決するために、鋭意検討の結果、押し子を押し続けると
いう単一の操作で投薬モードを変更できるプレフィルド
シリンジを採用することにより上記課題を解決できるこ
とに想到し、本発明を完成した。すなわち本発明は、両
端が開放された筒状体と、この筒状体の内腔に所定距離
隔てて液密かつ内壁に沿って摺動可能に挿着された、先
端側の第1のガスケットと中間の第2のガスケットおよ
び基端側の第3のガスケットを含んでなり、前記筒状体
には、長手軸に関して反対側の側壁に薬液の入口と出口
が設けられており、第2のガスケットと第3のガスケッ
トの間は薬液が充填された薬液室になっており、前記第
1のガスケットの基端と第2のガスケットの先端は密接
しており、この密接する第1のガスケットの基端と第2
のガスケットの先端の少なくとも一方、および前記薬液
室に面する第2のガスケットの基端と第3のガスケット
の先端の少なくとも一方には、前記筒状体の内径より小
さな外径を有する円柱状の突起が設けられており、前記
第1のガスケットは、第2のガスケットと密接した状態
で、前記第1のガスケットと第2のガスケットの間の円
柱状突起部分を介して前記薬液の入口と出口が連通する
位置から前記筒状体の先端まで移動可能であり、前記薬
液の入口は出口より先端側で前記筒状体の内腔に開口し
ており、前記第1のガスケットを筒状体の先端まで移動
させたときに、前記第2のガスケットの基端と第3のガ
スケットの先端が密接し、該密接した第2のガスケット
と第3のガスケットの間の円柱状突起部分を介して薬液
の出口と入口が連通するようにされてなる薬液注入器に
関する。ここで、筒状体の基端には第3のガスケットを
先端方向に移動させる押し子を設けてもよい。
Means for Solving the Problems In order to solve the above-mentioned problems, the present inventor has made intensive studies and, as a result, has adopted a pre-filled syringe which can change the medication mode by a single operation of keeping the pusher pressed. Having conceived of solving the problem, the present invention has been completed. That is, the present invention provides a cylindrical body having both open ends, and a first gasket on the distal end side which is slidably inserted along the inner wall of the cylindrical body at a predetermined distance with a predetermined distance therebetween. And an intermediate second gasket and a proximal third gasket, wherein the cylindrical body is provided with an inlet and an outlet for a chemical solution on a side wall opposite to the longitudinal axis. A space between the gasket and the third gasket is a liquid medicine chamber filled with a liquid medicine. A base end of the first gasket and a front end of the second gasket are in close contact with each other. Proximal and second
At least one of the distal end of the gasket and the proximal end of the second gasket facing the chemical solution chamber and at least one of the distal ends of the third gasket have a cylindrical shape having an outer diameter smaller than the inner diameter of the cylindrical body. A projection is provided, and the first gasket is in close contact with the second gasket, and has an inlet and an outlet of the chemical solution through a cylindrical projection between the first gasket and the second gasket. Can be moved from the position where is communicated to the distal end of the cylindrical body, the inlet of the chemical solution is open to the lumen of the cylindrical body at the distal end side from the outlet, and the first gasket is When moved to the distal end, the base end of the second gasket and the distal end of the third gasket come into close contact with each other, and the chemical solution passes through the cylindrical projection between the close-contacted second gasket and the third gasket. Exit and entrance About chemical injector comprising adapted to. Here, a pusher for moving the third gasket in the distal direction may be provided at the base end of the tubular body.

【0006】本発明の薬液注入器は、シリンジと接続し
て、心筋シンチグラフィーのために行う造影剤の血管注
入や、腎性貧血の治療のために行う透析回路へのホルモ
ン製剤の混注、骨粗鬆症の治療のためのペプチド製剤の
混注、抗癌剤の混注などに使用できるほか、輸液バック
やボトルにチューブを介して接続して、メイラード反応
を防止するために高カロリー輸液の開始直前にビタミン
剤を注入する場合などに使用できる。
The liquid injector according to the present invention is connected to a syringe to inject a contrast medium into blood vessels for myocardial scintigraphy, to co-inject hormonal preparations into a dialysis circuit for treating renal anemia, and to prevent osteoporosis. It can be used for co-infusion of peptide preparations and anti-cancer drugs for the treatment of cancer, and is connected to an infusion bag or bottle via a tube to inject vitamin preparations immediately before starting high-calorie infusion to prevent Maillard reaction It can be used when doing so.

【0007】[0007]

【発明の実施の形態】次に、本発明の実施例を図面に基
づいて説明する。図1は本発明の一実施例に係る縦断面
図であり、図2〜図4は本発明の薬液注入器の使用状態
を説明するための図である。図1に示すように、本発明
の薬液注入器は、筒状体1と、この筒状体1に挿着され
た3つのガスケット2、3、4を含んでなる。筒状体1
には、長手軸に関して反対側の側壁に薬液の入口13と
出口14が設けられており、2つのガスケット3、4の
間は薬液室5になっている。第1のガスケット2の基端
と第2のガスケット3の先端は密接しており、第1のガ
スケット2の基端と第2のガスケット3の両端および第
3のガスケット4の先端には、夫々筒状体1の内径より
小さな外径を有する円柱状の突起21、31、32、4
1が設けられている。第1のガスケット2は、第2のガ
スケット3と密接した状態で、円柱状突起21、31部
分を介して薬液の入口13、と出口14が連通する位置
から筒状体1の先端11まで移動可能である。薬液の入
口13は出口14より先端側で筒状体1の内腔に開口し
ており、第1のガスケット2を筒状体1の先端まで移動
させたときに、円柱状突起32、41部分を介して薬液
の出口13と入口14が連通するようになっている。
Next, an embodiment of the present invention will be described with reference to the drawings. FIG. 1 is a longitudinal sectional view according to an embodiment of the present invention, and FIGS. 2 to 4 are views for explaining a use state of the drug solution injector of the present invention. As shown in FIG. 1, the liquid injector according to the present invention includes a tubular body 1 and three gaskets 2, 3, and 4 inserted into the tubular body 1. Tubular body 1
Are provided with a chemical solution inlet 13 and an outlet 14 on the side wall opposite to the longitudinal axis, and a chemical solution chamber 5 is provided between the two gaskets 3 and 4. The proximal end of the first gasket 2 and the distal end of the second gasket 3 are in close contact, and the proximal end of the first gasket 2, both ends of the second gasket 3, and the distal end of the third gasket 4, respectively. Cylindrical projections 21, 31, 32, 4 having an outer diameter smaller than the inner diameter of the cylindrical body 1;
1 is provided. The first gasket 2 moves from the position where the inlet 13 and the outlet 14 of the chemical liquid communicate with each other through the columnar projections 21 and 31 to the tip 11 of the cylindrical body 1 in a state of being in close contact with the second gasket 3. It is possible. The inlet 13 for the chemical solution is open to the lumen of the cylindrical body 1 on the distal end side from the outlet 14, and when the first gasket 2 is moved to the distal end of the cylindrical body 1, the cylindrical projections 32 and 41 are formed. The outlet 13 and the inlet 14 of the chemical solution communicate with each other via the.

【0008】筒状体1は、両端11、12が開放されて
おり、その長手軸に関して反対側の側壁には薬液の入口
13と出口14が設けられ、薬液の入口13は出口14
より先端11側で筒状体1の内腔に開口している。筒状
体1の内腔には3つのガスケット2、3、4が液密かつ
その内壁に沿って摺動可能に挿着されており、第1のガ
スケット2と第2のガスケット3は密接しており、第2
のガスケット3と第3のガスケット4の間は所定距離隔
てられて薬液室5になっている。薬液室5には薬液(省
略されている)が充填されている。図中15はガスケッ
ト2の移動を停止するための環状突起である。
The cylindrical body 1 has both ends 11 and 12 open, and a chemical liquid inlet 13 and an outlet 14 are provided on the side wall opposite to the longitudinal axis.
It is open to the inner cavity of the tubular body 1 on the tip 11 side. Three gaskets 2, 3, and 4 are liquid-tightly and slidably inserted along the inner wall of the cylindrical body 1, and the first gasket 2 and the second gasket 3 are in close contact with each other. And the second
The gasket 3 and the third gasket 4 are separated by a predetermined distance to form a chemical solution chamber 5. The chemical solution chamber 5 is filled with a chemical solution (omitted). In the figure, reference numeral 15 denotes an annular projection for stopping the movement of the gasket 2.

【0009】先端11側の第1のガスケット2の基端と
中間の第2のガスケット3の先端には、筒状体1の内径
より小さな外径を有する円柱状の突起21、31が設け
られており、第1のガスケット2は、突起21、31を
介して筒状体1の薬液の入口13と出口14が連通する
位置から筒状体1の先端11まで摺動可能である。突起
21、31は両方にではなくどちらか一方に設けてもよ
い。従って、第2のガスケット3に突起31を設けた場
合、第1のガスケット2は、従来のもの、または従来の
ものに突起21を設けたものであってもよい。中間の第
2のガスケット3の基端と基端側の第3のガスケット4
の先端には、筒状体1の内径より小さな外径を有する円
柱状の突起32、41が設けられており、3つのガスケ
ット2、3、4を先端11方向に移動させた時、第1の
ガスケット2は、薬液の出口14から薬液が注出される
位置、すなわち薬液室5が突起32を介して薬液の出口
14と連通し入口13とは連通しない位置で自動的に停
止する。突起32、41は両方にではなくどちらか一方
に設けてもよい。従って、例えば第2のガスケット3に
突起32を設けた場合、第3のガスケット4は、従来の
もの、または従来のものに突起41を設けたものであっ
てもよい。薬液室5の薬液が無くなると、第2のガスケ
ット3と第3のガスケット4が密接し、3つのガスケッ
ト2、3、4が一緒に移動して第1のガスケット2が先
端11に達したときに停止する。このとき、薬液の入口
13と薬液の出口14は円柱状突起32、41部分を介
して連通する。
[0009] At the base end of the first gasket 2 on the side of the front end 11 and at the front end of the second gasket 3 in the middle, columnar projections 21 and 31 having an outer diameter smaller than the inner diameter of the tubular body 1 are provided. The first gasket 2 is slidable from a position where the inlet 13 and the outlet 14 of the chemical solution of the tubular body 1 communicate with each other via the projections 21 and 31 to the tip 11 of the tubular body 1. The projections 21 and 31 may be provided on one or the other instead of both. Therefore, when the projection 31 is provided on the second gasket 3, the first gasket 2 may be a conventional gasket or a conventional gasket provided with the projection 21. The base end of the intermediate second gasket 3 and the third gasket 4 on the base end side
Are provided with cylindrical projections 32 and 41 having an outer diameter smaller than the inner diameter of the cylindrical body 1. When the three gaskets 2, 3 and 4 are moved in the direction of the tip 11, the first The gasket 2 automatically stops at a position where the chemical solution is poured from the chemical solution outlet 14, that is, at a position where the chemical solution chamber 5 communicates with the chemical solution outlet 14 via the projection 32 and does not communicate with the inlet 13. The projections 32 and 41 may be provided on one or the other instead of both. Therefore, for example, when the projection 32 is provided on the second gasket 3, the third gasket 4 may be a conventional gasket or a conventional gasket provided with the projection 41. When the chemical liquid in the chemical liquid chamber 5 is exhausted, the second gasket 3 and the third gasket 4 come into close contact, and the three gaskets 2, 3, and 4 move together and the first gasket 2 reaches the tip end 11. To stop. At this time, the liquid medicine inlet 13 and the liquid medicine outlet 14 communicate with each other via the cylindrical projections 32 and 41.

【0010】筒状体1の基端には第3のガスケット4を
先端11方向に移動させる押し子6を設けてもよい。押
し子6としては、特に限定するものではないが、例えば
図1に示すような、筒状体1の外壁と係合し、容易に先
端11方向に移動させることが出来るキャップ状のもの
が好ましく採用される。図中、61は係合部、62は押
圧部であり、押し子6は、筒状体1の環状溝16と係合
部61の環状リブ611が係合する位置から、筒状体1
の段部17と環状リブ611が係合する位置まで移動可
能になっている。
A pusher 6 for moving the third gasket 4 in the direction of the distal end 11 may be provided at the base end of the tubular body 1. The pusher 6 is not particularly limited, but is preferably a cap-shaped pusher which engages with the outer wall of the tubular body 1 and can be easily moved in the direction of the tip 11 as shown in FIG. Adopted. In the figure, reference numeral 61 denotes an engaging portion, 62 denotes a pressing portion, and the pusher 6 moves the cylindrical member 1 from a position where the annular groove 16 of the cylindrical member 1 and the annular rib 611 of the engaging portion 61 engage.
Is movable to a position where the stepped portion 17 and the annular rib 611 are engaged.

【0011】次に、本発明の薬液注入器の使用について
図面を用いて説明する。図2〜図4は血管に造影剤を注
入する場合の使用例である。先ず、薬液室5に造影剤
(図示していない)の充填された薬液注入器Iを用意
し、その薬液の出口14に例えば翼状針(図示していな
い)を接続する。この時、第1のガスケット2は薬液の
入口13と出口14が突起21、31を介して連通する
位置にある。次に、図2に示すように、薬液注入器Iの
薬液の入口13に、生理食塩水(図示していない、以
下、生食という)を充填したシリンジSのチップ7を挿
着し、プランジャ8を押すと、シリンジSの生食は薬液
の入口13、突起21、31部分、出口14および翼状
針を通って流れ、造影剤の流路が洗浄される(プライミ
ングという)。
Next, the use of the liquid injector according to the present invention will be described with reference to the drawings. 2 to 4 show an example of use when a contrast agent is injected into a blood vessel. First, a drug solution injector I filled with a contrast agent (not shown) is prepared in the drug solution chamber 5, and a wing needle (not shown) is connected to the outlet 14 of the drug solution. At this time, the first gasket 2 is at a position where the inlet 13 and the outlet 14 of the chemical solution communicate with each other via the projections 21 and 31. Next, as shown in FIG. 2, a tip 7 of a syringe S filled with a physiological saline (not shown, hereinafter, referred to as raw food) is inserted into the inlet 13 of the liquid medicine injector I, and the plunger 8 is inserted. When the is pressed, the raw eclipse of the syringe S flows through the inlet 13, the projections 21 and 31, the outlet 14, and the wing needle of the liquid medicine, and the flow path of the contrast agent is washed (called priming).

【0012】プライミングが終了したら、翼状針の針を
患者の血管に刺入して血管を確保する。次に、薬液注入
器Iの押し子6を押すと、第3のガスケット4と薬液室
5および第2のガスケット3、第1のガスケット2が先
端方向に移動し、薬液室5が円柱状突起32部分を介し
て薬液の出口14に連通し入口13に連通しない位置で
停止する。このとき、薬液室5の造影剤は薬液の出口1
4から翼状針を介して血管に注入される(図3参照)。
薬剤室5の造影剤が空になると、2つのガスケット3、
4が密接して、3つのガスケット2、3、4が第1のガ
スケット2が先端11に達する位置まで一体的に移動す
る。この時、円柱状突起32、41部分を介して薬液の
入口13と出口14が連通する。次に、シリンジSのプ
ランジャ8を押すと、生食が薬液の入口13、円柱状突
起32、41部分、薬液の出口14および翼状針を通っ
て流れ、このとき、円柱状突起32、41部分、薬液の
出口14および翼状針の中に残っている造影剤が血管内
に流し込まれる(図4参照)。
After the priming is completed, a winged needle is inserted into a patient's blood vessel to secure the blood vessel. Next, when the pusher 6 of the drug solution injector I is pressed, the third gasket 4 and the drug solution chamber 5 and the second gasket 3 and the first gasket 2 move in the distal direction, and the drug solution chamber 5 is moved into a cylindrical projection. It stops at a position where it communicates with the outlet 14 of the chemical solution via the 32 portion and not with the inlet 13. At this time, the contrast agent in the drug solution chamber 5 is supplied to the outlet 1 of the drug solution.
4 is injected into the blood vessel via the winged needle (see FIG. 3).
When the contrast agent in the medicine room 5 becomes empty, two gaskets 3
4, the three gaskets 2, 3, 4 move integrally to a position where the first gasket 2 reaches the tip 11. At this time, the inlet 13 and the outlet 14 of the chemical solution communicate with each other via the cylindrical projections 32 and 41. Next, when the plunger 8 of the syringe S is pushed, the raw food flows through the inlet 13 of the drug solution, the columnar projections 32 and 41, the outlet 14 of the drug solution and the wing needle, and at this time, the columnar projections 32 and 41, The contrast agent remaining in the drug solution outlet 14 and the wing needle flows into the blood vessel (see FIG. 4).

【0013】[0013]

【発明の効果】以上述べたことから明らかなように、本
発明によれば、以下のような効果が期待できる。押し子
を押し続けるだけの単純な操作で投薬モードを変更でき
るので、操作が簡単である。また、投薬の途中で別の薬
液を連続して投与できるので、高価な薬液を少量投与す
る場合に便利であり、この場合、他の薬液と混合するよ
うに投与するものではないので濃度が希薄になることも
無く、効果的な投与が出来る。高価な薬液の投与後再び
安価な薬液を投与することにより、高価な薬液の残液を
流し込むことが出来るので、高価な薬液を無駄にしない
で済む。
As is apparent from the above description, according to the present invention, the following effects can be expected. Since the medication mode can be changed by a simple operation of simply holding down the pusher, the operation is simple. In addition, another medicinal solution can be continuously administered during the administration, which is convenient for administering a small amount of an expensive medicinal solution. In this case, the concentration is low because the medicinal solution is not administered so as to be mixed with another medicinal solution. And can be administered effectively. By administering the inexpensive liquid medicine again after the administration of the expensive liquid medicine, the remaining liquid of the expensive liquid medicine can be poured, so that the expensive liquid medicine is not wasted.

【図面の簡単な説明】[Brief description of the drawings]

【図1】本発明の一実施例に係る縦断面図である。FIG. 1 is a longitudinal sectional view according to an embodiment of the present invention.

【図2】本発明の薬液注入器の使用状態を説明するため
の図である。
FIG. 2 is a diagram for explaining a use state of the drug solution injector according to the present invention.

【図3】本発明の薬液注入器の使用状態を説明するため
の図である。
FIG. 3 is a diagram for explaining a use state of the drug solution injector according to the present invention.

【図4】本発明の薬液注入器の使用状態を説明するため
の図である。
FIG. 4 is a diagram for explaining a use state of the drug solution injector according to the present invention.

【符号の説明】[Explanation of symbols]

1 筒状体 11 先端 12 基端 13 薬液の入口 14 薬液の出口 15 環状突起 16 環状溝 17 段部 2 第1のガスケット 21 突起 3 第2のガスケット 31 突起 32 突起 4 第3のガスケット 41 突起 5 薬液室 6 押し子 61 係合部 611 環状リブ 62 押圧部 7 チップ 8 プランジャ S シリンジ I 薬液注入器 DESCRIPTION OF SYMBOLS 1 Cylindrical body 11 Tip 12 Base end 13 Chemical liquid inlet 14 Chemical liquid outlet 15 Annular projection 16 Annular groove 17 Stepped part 2 First gasket 21 Projection 3 Second gasket 31 Projection 32 Projection 4 Third gasket 41 Projection 5 Chemical solution chamber 6 Pusher 61 Engagement part 611 Annular rib 62 Pressing part 7 Tip 8 Plunger S Syringe I Chemical solution injector

Claims (2)

【特許請求の範囲】[Claims] 【請求項1】 両端が開放された筒状体と、該筒状体の
内腔に所定距離隔てて液密かつ内壁に沿って摺動可能に
挿着された、先端側の第1のガスケットと中間の第2の
ガスケットおよび基端側の第3のガスケットを含んでな
り、前記筒状体には、長手軸に関して反対側の側壁に薬
液の入口と出口が設けられており、第2のガスケットと
第3のガスケットの間は薬液が充填された薬液室になっ
ており、前記第1のガスケットの基端と第2のガスケッ
トの先端は密接しており、該密接する第1のガスケット
の基端と第2のガスケットの先端の少なくとも一方、お
よび前記薬液室に面する第2のガスケットの基端と第3
のガスケットの先端の少なくとも一方には、前記筒状体
の内径より小さな外径を有する円柱状の突起が設けられ
ており、前記第1のガスケットは、第2のガスケットと
密接した状態で、前記第1のガスケットと第2のガスケ
ットの間の円柱状突起部分を介して前記薬液の入口と出
口が連通する位置から前記筒状体の先端まで移動可能で
あり、前記薬液の入口は出口より先端側で前記筒状体の
内腔に開口しており、前記第1のガスケットを筒状体の
先端まで移動させたときに、前記第2のガスケットの基
端と第3のガスケットの先端が密接し、該密接した第2
のガスケットと第3のガスケットの間の円柱状突起部分
を介して薬液の出口と入口が連通するようにされてなる
薬液注入器。
1. A cylindrical body having both ends open, and a first gasket on a distal end side, which is slidably inserted along an inner wall of the cylindrical body at a predetermined distance with a predetermined distance therebetween. And an intermediate second gasket and a proximal third gasket, wherein the cylindrical body is provided with an inlet and an outlet for a chemical solution on a side wall opposite to the longitudinal axis. A space between the gasket and the third gasket is a liquid medicine chamber filled with a liquid medicine. The base end of the first gasket and the front end of the second gasket are in close contact with each other. At least one of a proximal end and a distal end of the second gasket, and a proximal end and a third end of the second gasket facing the chemical solution chamber.
At least one of the ends of the gasket is provided with a columnar projection having an outer diameter smaller than the inner diameter of the cylindrical body, and the first gasket is in close contact with the second gasket, The liquid medicine can be moved from a position where the inlet and the outlet of the chemical liquid communicate with each other to a tip end of the cylindrical body through a columnar projection between the first gasket and the second gasket, and the inlet of the chemical liquid is more distal than the outlet. The first gasket is moved to the distal end of the cylindrical body, and the proximal end of the second gasket and the distal end of the third gasket are in close contact with each other. And the close second
A liquid injector in which an outlet and an inlet of the liquid medicine communicate with each other via a columnar projection between the gasket and the third gasket.
【請求項2】 筒状体の基端に第3のガスケットを先端
方向に移動させる押し子を設けてなる請求項1に記載の
薬液注入器。
2. The liquid injector according to claim 1, wherein a pusher for moving the third gasket in a distal direction is provided at a base end of the cylindrical body.
JP2001135913A 2001-03-21 2001-05-07 Chemical solution injector suitable for small doses Expired - Fee Related JP3973854B2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2001135913A JP3973854B2 (en) 2001-05-07 2001-05-07 Chemical solution injector suitable for small doses
US10/097,485 US6929620B2 (en) 2001-03-21 2002-03-15 Injector for liquid medicine
EP20020005392 EP1243280B1 (en) 2001-03-21 2002-03-15 Injector for liquid medicine
DE60232388T DE60232388D1 (en) 2001-03-21 2002-03-15 Injector for liquid medication
US11/142,442 US7351229B2 (en) 2001-03-21 2005-06-02 Injector for liquid medicine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2001135913A JP3973854B2 (en) 2001-05-07 2001-05-07 Chemical solution injector suitable for small doses

Publications (2)

Publication Number Publication Date
JP2002325845A true JP2002325845A (en) 2002-11-12
JP3973854B2 JP3973854B2 (en) 2007-09-12

Family

ID=18983297

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001135913A Expired - Fee Related JP3973854B2 (en) 2001-03-21 2001-05-07 Chemical solution injector suitable for small doses

Country Status (1)

Country Link
JP (1) JP3973854B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009102868A1 (en) * 2008-02-12 2009-08-20 Celonova Biosciences, Inc. Delivery systems and related methods for convenient preparation of particles for in vivo administration

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009102868A1 (en) * 2008-02-12 2009-08-20 Celonova Biosciences, Inc. Delivery systems and related methods for convenient preparation of particles for in vivo administration

Also Published As

Publication number Publication date
JP3973854B2 (en) 2007-09-12

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