JP2002255709A - Fungicide for controlling infectious disease and downy mildew - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a fungicide which exhibits excellent control effects on infectious diseases and downy mildew. SOLUTION: This fungicide for controlling infectious diseases and downy mildew is characterized by containing N-(2-chloro-4-nitrophenyl)-3- trifluoromethylbenzenesulfonamide compound. The compound exhibits excellent control effects, when used against infectious diseases and downy mildew.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a novel fungicide for controlling plague and downy mildew.

[0002]

2. Description of the Related Art Conventionally, one of the major obstacles in crop cultivation is one.
One is crop diseases. Among the diseases, plague and downy mildew are among the most difficult to control. The reason for this is that the generation of resistant bacteria has been observed with a drug having a high control effect (phenylamide-based drug), and the control effect of the drug has been reduced. The occurrence of resistant bacteria results in an increase in the amount of drug and an increase in the burden on the environment. In order to prevent the occurrence of resistant bacteria and maintain a high control effect, attempts have been made by means of developing a mixed agent by combining existing agents having different actions, and limiting the number of times the agent itself is used.

[0003] Many sulfonamide compounds have been synthesized for a long time, and many studies have been made on their physiological activities. In the agricultural field, research is being conducted on pesticides as well as herbicides and fungicides. For example, as herbicides, there are JP-B-39-29571 and JP-B-40-19199.
No. 9304, JP-B-45-6836, JP-B-46-6797, JP-B-47-15119, JP-A-57-31655, JP-A-58-118558 and JP-A-58 -219159 and the like. As insecticides, US Patent 3,034,95
No. 5 gazette.

[0004] Among sulfonamide compounds,
N- (2-chloro-4-nitrophenyl) -3-trifluoromethylbenzenesulfonamide compound (hereinafter abbreviated as fursulfamide) is disclosed in Japanese Patent Publication No. Hei 6-27113, the clubroot disease of cruciferous vegetables and potato soybean. It is described that it shows an excellent control effect on scab, potato powder scab and various Aphanomyces fungi. However, there is no mention or suggestion of application to other diseases.

[0005]

SUMMARY OF THE INVENTION The present invention relates to a novel plague,
It is an object to provide a fungicide for controlling downy mildew.

[0006]

DISCLOSURE OF THE INVENTION The present inventors have found that flusulfamide has high physiological activity against plague and downy mildew, which are diseases that cannot be predicted at all from known literatures, and does not cause phytotoxicity on crops. The present inventors have found that the above problem has been solved.

That is, the present invention relates to N- (2-chloro-4-
A fungicide for controlling plague and downy mildew, which is a composition containing (nitrophenyl) -3-trifluoromethylbenzenesulfonamide.

[0008]

BEST MODE FOR CARRYING OUT THE INVENTION The N- (2-chloro-4) according to the present invention
-Nitrophenyl) -3-trifluoromethylbenzenesulfonamide compound (flusulfamide) is a compound known per se, and can be produced by a known production method.

When the composition containing flusulfamide is used as an agent for controlling plague and downy mildew, the drug substance may be used as it is for the plant to be treated, but generally an inert liquid carrier, It is mixed with a solid carrier and a surfactant and used in the form of powders, wettable powders, granules, flowables, emulsions and other commonly used forms which are usually used. If necessary for the preparation, an auxiliary agent can be added.

[0010] The carrier used herein is a synthetic or natural inorganic or organic substance incorporated to assist in reaching the active ingredient to the site to be treated and to facilitate storage, transport and handling of the active ingredient compound. Means As the carrier, any solid or liquid carrier can be used as long as it is generally used for agricultural and horticultural medicines, and it is not limited to a specific carrier. For example, as a solid carrier,
Viscosity such as montmorillonite, kaolinite, diatomaceous earth,
Inorganic substances such as clay, talc, vermiculite, calcium carbonate, silica gel, ammonium sulfate, etc., vegetable organic substances such as flour, soy flour, starch, crystalline cellulose, petroleum resins, polymer compounds such as polyalkylene glycol, urea, waxes, etc. can give. As a liquid carrier, toluene,
Aromatic hydrocarbons such as xylene and cumene, kerosene,
Paraffinic hydrocarbons such as mineral oil, ketones such as acetone, methyl ethyl ketone and dicyclohexanone, ethers such as dioxane and diethylene glycol dimethyl ether, methanol, ethanol, propanol,
Examples include alcohols such as ethylene glycol, aprotic solvents such as dimethylformamide and dimethylsulfoxide, and water.

Further, the following auxiliaries can be added singly or in combination according to the purpose in consideration of the dosage form of the preparation, the application scene, and the like. Examples of the auxiliary include commonly used surfactants and binders (eg, ligninsulfonic acid, alginic acid, polyvinyl alcohol,
Gum arabic, sodium CMC, etc.) stabilizers (eg,
A phenol compound, a thiol compound, a higher fatty acid ester, or the like for antioxidation, a phosphate as a pH regulator, or a light stabilizer may be used alone or in combination as necessary. Further, depending on the case, an industrial bactericide, a bactericidal / antifungal agent or the like may be added for bactericidal / fungicidal purposes.

The surfactant which can be used in the fungicide of the present invention is a compound used for the purpose of emulsification, dispersion, spreading, wetting, binding, stabilization, etc., for example, lignin sulfonate, alkylbenzene sulfone Acid salt, alkyl sulfate salt, polyoxyalkylene alkyl sulfate,
Anionic surfactant such as polyoxyalkylene alkyl phosphate ester salt, polyoxyalkylene alkyl ether, polyoxyalkylene alkyl aryl ether, polyoxyalkylene alkylamine, polyoxyalkylene alkylamide, polyoxyalkylene alkylamide, polyoxyalkylene Lubrication of nonionic surfactants such as alkylthioethers, polyoxyalkylene fatty acid esters, glycerin fatty acid esters, sorbitan fatty acid esters, polyoxyalkylene sorbitan fatty acid esters, polyoxypropylene polyoxyethylene block polymers, stearic acid, calcium, wax, etc. Agents, stabilizers such as isopropylhydrodiene phosphate, phosphatidylethanolamine, phosphatidyl Phosphorus, phosphatidyl glycerol, natural or synthetic phospholipids of the cephalin or lecithin type such as lysolecithin, other cellulose, carboxymethyl cellulose, casein, gum arabic and the like. However, these components are not limited to those described above.

The active ingredient in the form of various preparations is usually a powder,
The wettable powder, granule, and flowable are desirably 0.1 to 80% by weight.

The content of the adjuvant is 0 to 80% by weight, and the content of the carrier is 100% by weight minus the content of the active ingredient compound and the adjuvant.

[0015] As a method of applying the composition containing flusulfamide, foliage application is most effective.

The application rate and application concentration vary depending on the target crop, the degree of disease occurrence, the compound dosage form, the application method and various environmental conditions. When spraying, 0.1 to 10 kg of the active ingredient is treated per hectare. And preferably 0.5 to 5 kg per hectare. When using wettable powders, flowables or emulsions,
It may be used after dilution with water.

When using a composition containing flusulfamide, at the same time other pesticides such as insecticides, fungicides,
Not only can they be used in combination with miticides, nematicides, antiviral agents, herbicides, and plant regulators, but also mixed preparations with these can be used.

[0018]

EXAMPLES Next, examples of the preparation of a bactericide containing a composition containing flusulfamide as an active ingredient are shown, but the types and mixing ratios of the additives are not limited thereto.
Parts in the preparation examples represent parts by weight.

Formulation Example 1 Flowable agent Flusulfamide 5 parts, propylene glycol 3 parts, sodium ligninsulfonate 14 parts, gum arabic 1 part,
77 parts of water was mixed and pulverized with a sand grinder to obtain a flowable agent.

Formulation Example 2 Flowable agent Flusulfamide 10 parts, polyethylene sorbitan monooleate 3 parts, carboxymethyl cellulose 5 parts and water
82 parts were mixed and pulverized with a sand grinder to obtain a flowable agent.

Formulation Example 3 Wettable powder 5 parts of Flusulfamide, 15 parts of Solpol (surfactant manufactured by Toho Chemical Co., Ltd.) and 80 parts of Radiolite (calcined diatomaceous earth manufactured by Showa Chemical Co., Ltd.) are uniformly pulverized and mixed. A sum was obtained.

Formulation Example 4 Wettable powder Flusulfamide 5 parts, Carplex No. 80 (white carbon manufactured by Shionogi & Co., Ltd.) 15 parts, Emar 10
10 parts (surfactant manufactured by Kao Corporation) and 70 parts of clay were uniformly mixed and pulverized to obtain a wettable powder.

Test Example 1 Test for Preventive Effect on Tomato Blight Disease Tomato (variety: world's best) grown in a greenhouse in a plastic pot having a diameter of 7.5 cm up to the 5th leaf stage has a predetermined concentration of a flowable prepared according to Formulation Example 1. And sprayed 50 ml per 4 pots. After the drug dries, the zoospores are washed off with water from the disease-producing fungus cultured on the potato slices, and the zoospores are emerged after cooling on ice (1 × 10 ⁵ / m).
Spray inoculation in l). For a greenhouse with a temperature of 18 ° C and a humidity of 95% or more
After keeping for 5 days, the area occupied by the disease spot of the plague was investigated according to the following index to determine the degree of disease occurrence, and the control value was calculated according to the following formula. The results are shown in Table 1 (Table 1). The average value of each treated section and the untreated section was defined as the disease severity.

Control value = (1−Degree of disease in treated plot /
Degree of disease in untreated area) x 100

[0025]

[Table 1]

Test Example 2 Test for Preventive Effect of Cucumber Downy Mildew A flowable agent prepared according to Formulation Example 2 on a cucumber (variety: Sagami Hanshiro) grown in a greenhouse in a plastic pot having a diameter of 7.5 cm until the 1.5 leaf stage. Is diluted to a predetermined concentration, and 4
50 ml was sprayed per pot. After the drug was dried, a spore suspension of cucumber downy mildew (1 × 10 ⁵ cells / ml) was spray-inoculated. After being kept in a greenhouse at a temperature of 25 ° C. and a humidity of 95% or more for 7 days, the area occupied by mildew spots was investigated according to the following index to determine the degree of onset, and the control value was calculated according to the following formula. The results are shown in Table 2 (Table 2). The average value of each treated section and the untreated section was defined as the disease severity.

Control value = (1−Severity of treated plot /
Degree of disease in untreated area) x 100

[0028]

[Table 2]

Test Example 3 Tomato Blight Field Test A five-leaf tomato seedling (variety: the best in the world) was planted at intervals of 50 cm by two-row planting in a field having a ridge width of 1.2 m. Formulation Example 3 2 weeks after planting
Dilute the wettable powder prepared according to
It was sprayed on the foliage of tomato with a liquid amount equivalent to 0a. After the drug dries, the zoospores are washed off with water and the spore suspension (1 × 10 ⁵ cells / ml) from which the zoospores emerge is washed with water from the disease-causing fungus cultured on the potato slices. Was spray-inoculated with a liquid amount equivalent to 45 L / 10a. In order to promote the onset of the disease, watering was performed until the foliage was sprayed wet using a watering tube. Seven days after the chemical treatment, the area occupied by the disease spot of the plague which appeared on the tomato foliage was investigated according to the same index as in Test Example 1 to determine the degree of disease onset.
The control value was calculated according to the formula described in Test Example 1. The results are shown in Table 3 (Table 3).

[0030]

[Table 3]

Test Example 4 Potato Blight Field Test A potato seed potato (variety: baron) was planted at intervals of 50 cm by two-row planting in a field having a ridge width of 1.2 m. Two months after planting, the wettable powder prepared according to Formulation Example 4 was diluted to a predetermined concentration,
It was sprayed on the foliage of potatoes with a liquid volume equivalent to 50 L / 10 a.
After the drug dries, the zoospores are washed off with water and the spore suspension (1 × 10 ⁵ cells / ml) from which the zoospores emerge is washed with water from the disease-causing fungus cultured on the potato slices. Was spray-inoculated with a liquid amount equivalent to 45 L / 10a. In order to promote the onset of the disease, watering was performed until the foliage was sprayed wet using a watering tube. Seven days after the chemical treatment, the area occupied by the plague lesions appearing on the potato foliage was examined according to the same index as in Test Example 1 to determine the degree of onset, and the control value was calculated according to the formula described in Test Example 1. The results are shown in Table 4 (Table 4).

[0032]

[Table 4]

[0033]

As is clear from the results of the above test examples,
The composition containing flusulfamide shows an excellent control effect against plague and downy mildew, and is of great value in crop production.

 ────────────────────────────────────────────────── ─── Continued on the front page (72) Inventor Hideo Kawashima 1144 Togo, Mobara-shi, Chiba F-term (reference) 4H011 AA01 BA01 BB07 BC03 BC06 BC20 BC22 DA02 DA15 DC01 DC05 DD03 DE15

Claims (1)

[Claims] 1. N- (2-chloro-4-nitrophenyl)-
A fungicide for controlling plague and downy mildew, comprising 3-trifluoromethylbenzenesulfonamide.