JP2002028233A - Cap of instrument for hematocatharsis and instrument mounted with the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a cap of an instrument for hematocatharsis which facilitates an inventory management, improves mounting workability to a dialyzer and can be reduced in a manufacturing cost and the instrument mounted therewith. SOLUTION: This cap is made mountable to a blood side port by being fitted therein and is mounted to a dialyzer side port with liquid-tightness when the cap is fitted into this port from one end side. When the cap is fitted into the dialyzer side port from the other side end, the cap is mounted thereto with air permeability.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a blood purifier equipped with a blood-side port for introducing or withdrawing blood and a dialysate-side port for introducing or withdrawing dialysate. The present invention relates to a blood purifier cap and a blood purifier equipped with the same.

[0002]

2. Description of the Related Art A hollow fiber dialyzer (dialyzer) used for hemodialysis in a blood purification treatment is provided with a plurality of hollow fiber membranes in a cylindrical casing, thereby forming an inner cell of each hollow fiber membrane. A blood-side flow path formed, and a dialysate-side flow path formed between the outer peripheral surface of the hollow fiber membrane and the inner surface of the cylindrical casing and between adjacent hollow fiber membranes, At both ends of the flow path, a blood inlet port and a blood outlet port for introducing blood (collectively referred to as a blood-side port) are formed. A dialysate inlet and a dialysate outlet (to be collectively referred to as a dialysate side port) to be introduced are formed. The dialysate side port is EN1283,
It is formed based on standards such as DIN58352 and ISO8637. Regarding the blood side port shape, the slip-in type is the mainstream in Japan, but each shape, opening diameter, and outer diameter are changed so that if the circuit connection on the dialysate side and blood side is mistaken, it can not be connected .

[0003] Generally, in the case of a dry type dialyzer, the dialysate side port is left open without a cap attached thereto, while the blood side port is provided with an air permeable cap to prevent contamination. After being mounted, they were placed in a sterilization packaging bag and subjected to various sterilizations such as steam sterilization, γ-ray sterilization, and gas sterilization.

After using the dialyzer, the line connected to the dialysate-side port is disconnected, and a liquid-tight cap is provided to prevent the dialysate remaining in the dialysate-side flow path from leaking outside. It was attached and discarded. Conventionally, as such a liquid-tight cap, the cap attached to the blood port is inverted and attached (fitted from the other end).

That is, the cap is configured to be fitted with air permeability when fitted to the blood port from one end, and to be fitted with fluid tightness when fitted to the dialysate port from the other end. Was. Here, the blood side port and dialysate side port of a general dialyzer are:
The circuits to be connected to these ports are different in shape, opening diameter, and outer diameter so that the user does not mistake them, so the cap was matched from one end and matched from the other end. In each case, the cap and each port are configured to match while maintaining air permeability or liquid tightness.

Further, in the case of a general wet-type dialyzer, a liquid-tight cap is attached to both the blood port and the dialysate port in order to prevent leakage of the filling liquid.
Various sterilizations such as γ-ray sterilization and steam sterilization were performed, but even with the general cap attached here, it is attached to the blood side port due to the difference in shape and diameter between the blood side port and the dialysate side port. The shape differs between the one to be attached and the one attached to the dialysate side port.

[0007]

However, in the case of a cap to be attached to the above-mentioned wet type dialyzer, the shape and the material are different between those attached to the blood side port and those attached to the dialysate side port. It was necessary to prepare caps corresponding to each. On the other hand, in a dry-type dialyzer, when it is necessary to keep the inside of the sterilization packaging bag in a vacuum state until immediately before use (that is, in the case of vacuum packaging), the packaging bag comes into close contact with the dialyzer. Here, when the cap is not attached to the dialysate side, the packaging bag itself sinks into the opening of the dialysate port, and a very strong stress is applied to the packaging bag in this portion, and there is a problem that the packaging bag is torn. In order to solve this, it was necessary to prepare a separate cap and attach it to the dialysate-side port.

[0008] As described above, if it is necessary to prepare a plurality of types of caps, it is not easy to manage the stock of the caps, and the operator may be wondering how many types of caps need to be prepared in the cap mounting work. And there is a problem that workability may be deteriorated. Further, there is another problem that since a molding die for producing each cap is separately required, the production cost is deteriorated.

Further, in the case of the cap to be attached to the dry type dialyzer, the blood side port and the dialysate side port are also used, and although the problem of inventory management is somewhat solved, the cap on the dialysate side port is used. On the other hand, when mounted, it is only a liquid-tight one for the purpose of preventing leakage of dialysis fluid at the time of disposal, and requires a breathable cap for the purpose of preventing contamination during various sterilization described above. In such a case, there was a problem that a separate cap was required. Therefore, even a cap to be attached to a conventional dry-type dialyzer is insufficient for facilitating inventory management.

SUMMARY OF THE INVENTION The present invention has been made in view of the above circumstances, and has a blood purifier cap that can facilitate inventory control, improve the workability of mounting on a dialyzer, and reduce the manufacturing cost. It is to provide a blood purifier.

[0011]

According to the first aspect of the present invention,
In a blood purifier cap attached to each port of a blood purifier including a blood-side port for introducing or discharging blood, and a dialysate-side port for introducing or discharging a dialysate, the blood-side port and It is fitted to one of the dialysis fluid-side ports and can be attached to the port, and when fitted to the other port from one end, it is attached with liquid tightness and attached to the other port from the other end. It is characterized by being fitted with air permeability when fitted.

According to such a configuration, when fitting to one port and attaching it with air permeability or liquid tightness, and fitting it to the other port from one end side and attaching it with liquid tightness, It is also possible to fit one of the ports and attach it with air permeability or liquid tightness, and to fit the other port from the other end side and attach it with air permeability.

According to a second aspect of the present invention, in the blood purifier, a plurality of hollow fiber membranes are loaded in a cylindrical casing to form a blood-side flow path formed by inner vesicles of each hollow fiber membrane. A dialysate-side flow path formed between the outer peripheral surface of the hollow fiber membrane and the inner surface of the cylindrical casing and between adjacent hollow fiber membranes, wherein the blood-side port is a blood-side flow path. And the dialysate-side port is a port for dialysate introduction and discharge of a dialysate-side flow path.

The invention according to claim 3 is characterized in that the one port is the blood port and the other port is the dialysate port.

According to a fourth aspect of the present invention, the cap according to any one of the first to third aspects is mounted on the blood-side port and the dialysate-side port.

[0016]

Embodiments of the present invention will be specifically described below with reference to the drawings. The dialyzer to which the blood purifier cap according to the first embodiment of the present invention is attached has a cylindrical casing 1, a header 3, and a cap 8, as shown in FIGS. 5A and 5B, for example. It is a dry type element. The cap 8 as an embodiment according to the present invention includes a blood inlet 4 and a blood outlet 5 formed to extend from the header 3, and a dialysate outlet 6 and a dialysate formed to extend from the cylindrical casing 1. They are fitted and mounted on each of the liquid introduction ports 7 and will be described later in detail.

The cylindrical casing 1 forms a housing of the dialyzer 9, and is made of a transparent or translucent member in order to secure the internal visibility. At both ends,
A dialysate inlet 7 for flowing dialysate into the dialyzer 9 and a dialysate outlet 6 for discharging dialysate outside the hollow fiber blood purifier 13 in a direction orthogonal to the axis of the cylindrical casing 1. Are formed. The shapes of the dialysate inlet 7 and the dialysate outlet 6 are formed in accordance with DIN 58352.

The tubular casing 1 is filled with a plurality (usually several hundred to several tens of thousands) of hollow fiber membranes 2 inside the casing. A blood-side channel 2a (see FIG. 6) and a dialysate-side channel 2b are formed in the casing 1.

That is, the blood-side flow path 2a is formed by the inner vesicles (in the hollow portion) of a large number of hollow fiber membranes 2 whose openings at both ends communicate with the blood inlet 4 and the blood outlet 5, respectively. The dialysate-side flow path 2b communicates with the dialysate inlet 7 and the dialysate outlet 6, and is formed between the outer peripheral surface of the hollow fiber membrane 2 and the inner surface of the cylindrical casing 1 and between each adjacent hollow fiber membrane 2. Formed by a number of flow paths.

The hollow fiber membrane 2 loaded in the cylindrical casing 1 is integrated by the sealing portions 16 at both ends fixed with a sealing agent, and is sealed (liquid-tight) by an O-ring 17. Have been.

Headers 3 are screwed to both ends of the cylindrical casing 1, respectively, and blood is introduced into the blood-side flow path 2a in the axial direction of the cylindrical casing 1 at the protruding end of the header 3. A port 4 and a blood outlet 5 for discharging blood in the blood-side flow path 2a to the outside are formed.

The dialysate flows from the dialysate inlet 7 to the dialysate outlet 6 through the dialysate-side flow path 2b by a dialyser (not shown), and blood flows from the blood inlet 4 to the blood outlet 9. To the contrary, the blood flows in the blood channel 2a so as to face the dialysate. During passage through the blood-side flow path 2a, waste matter in the blood is dialyzed and removed to the dialysate side via the hollow fiber membrane.

Here, the blood inlet 4 and the blood outlet 5
The (blood side port), the dialysate outlet port 6 and the dialysate inlet port 7 (dialysate side port) have a shape, an opening diameter, and a circuit to be connected to these ports so that the user does not make a mistake.
And the diameter of the outer periphery is different (the blood-side port has a smaller opening diameter than the dialysate-side port), and the cap 8 can be fitted to each port while maintaining air permeability or liquid tightness. Is installed. Hereinafter, the cap 8 will be described in detail with reference to FIGS.

The cap 8 is made of a material such as ethylene propylene rubber, silicone rubber, thermoplastic elastomer, etc., in addition to general-purpose plastics such as polyethylene and polypropylene, and has one end 8a and the other end 8b.
And a flange 8c, and these parts are integrally formed.

The cap 8 is formed in a cylindrical shape as a whole, and a rib 11 extending in the axial direction of the cap 8 from four sides of the inner peripheral surface 10a toward the center thereof is protrudingly provided. A flange 12 is annularly protruded from an outer peripheral surface 10b in an outer peripheral direction to form a flange 8c. The flange 12 has an L-shaped cross section that is open downward, and four reinforcing ribs 12a extending in the outer peripheral direction from the outer peripheral surface 10b are formed on the lower surface thereof as shown in the figure. A portion where the reinforcing rib 12a is not formed is referred to as a ribless portion 12b.

Further, on the outer peripheral surface 10b extending from the flange 8c to the other end 8b, four grooves 13 extending in the axial direction of the cap 8 are formed at substantially equal intervals on the circumference. It continues to the open end (the other end B) of the end 8b. Cap 8
A concave portion 14 is formed in the vicinity of the central portion of the top portion (one end A), and a convex portion 15 projecting downward in the drawing is formed inside the cap 8 corresponding to the concave portion 14.

The outer diameter dimension s of the one end A is designed to be slightly smaller than the inner diameter of the dialysate-side port (6, 7), so that it can fit into the dialysate-side port (6, 7) from one end A side. Have been. On the other hand, the inner diameter t of the other end B is designed to be slightly larger than the outer diameter of the blood-side port (4, 5), and the outer diameter u is slightly larger than the inner diameter of the dialysate-side port (6, 7). Designed small, blood side port (4, 5)
And it is configured to be able to fit into the dialysate side port (6, 7) from the other end B side.

When the cap 8 is fitted to the blood side ports (4, 5) from the other end B side, the cap 8 is attached with air permeability as shown in FIG. That is, a gap is formed between the outer peripheral wall surface of the blood-side port (4, 5) and the inner peripheral surface 10a of the cap 8 by the protrusion size of the rib 11, while the inner diameter of the other end B side is changed to the blood-side port (4, 5). ), The cap 8 is formed such that a slight gap is formed between the outer peripheral surface and the inner peripheral surface 10a on the other end B side and the blood side port (4, 4). A gap is also formed between the outer peripheral wall surface and the outer peripheral wall surface of 5).
, And extend to an inner diameter smaller than the outer diameter of the blood-side port. Therefore, there are gaps also at the top, and the air is ventilated through these gaps as indicated by an arrow m.

When the cap 8 is fitted to the dialysate side port (6, 7) from one end A side, the cap 8
Is mounted with liquid tightness as shown in FIG. That is, one end 8a is inserted into the dialysate-side port (6, 7), and
The flange 8c shields the opening to prevent ventilation, and is configured to have liquid tightness.

Further, when the cap 8 is fitted to the dialysate-side port (6, 7) from the other end B side, the cap 8
Is mounted with air permeability as shown in FIG. That is, when the other end 8b is inserted into the dialysate-side port (6, 7), the recess formed by the groove 13 forms the dialysate-side port (6, 7).
While a gap is formed between the inner peripheral wall surface of 7) and the outer peripheral surface 10b of the cap 8, the inner diameter of the flange 8c is formed slightly larger than the outer diameter of the dialysate-side port (6, 7).
A gap is also formed between the inner peripheral surface of the flange portion 8c and the outer peripheral wall surface of the dialysate-side port (6, 7).
The end of the dialysate-side port abuts on a (FIG. 9).
However, there is a gap in the ribless portion 12b. It is configured to ventilate through these gaps as indicated by arrow n.

Next, the cap 8 is attached to the dialyzer 9.
A description will be given of an example of use in a case where the camera is mounted on each port.
FIG. 5 (a) shows a state in which the cap 8 is attached in a state in which the blood side ports (4, 5) are permeable, and the dialysis fluid side ports (6, 7) are also permeable. Shows dialyzer 9 with cap 8 attached.
That is, the cap 8 is fitted to the blood side port (4, 5) and the dialysate side port (6, 7) from the other end B side.

In this state, since each port has air permeability, for example, when performing sterilization such as steam sterilization or gas sterilization, the steam or gas used is supplied to the blood-side flow path 2a and the dialysate-side flow. When the dialyzer 9 enters the passage 2b and can be effectively sterilized, and the dialyzer 9 is vacuum-packed with the sterilization packaging bag before the sterilization, a part of the sterilization packaging bag is used as the dialysate-side port (6, 7). Can be prevented from being sucked into.

After the dialyzer 9 is used, the liquid tightness is improved by fitting the cap 8 to the dialysate side port (6, 7) from one end A side as shown in FIG. Since the cap 8 can be attached to the dialyser, the dialyzer 9 can be discarded while preventing the dialysate remaining in the dialysate-side flow path from leaking outside. In the blood side ports (4, 5), the blood circuit is discarded while being connected, so that it is not necessary to attach the cap 8.

Next, a second embodiment according to the present invention will be described. As shown in FIGS. 11 to 13, the cap for a blood purifier according to the present embodiment does not have the rib 11 formed in the first embodiment, and the other components are the same. Note that the same components as those in the first embodiment are denoted by the same reference numerals.

When the cap 8 'is fitted to the blood-side ports (4, 5) from the other end B side, as shown in FIG.
Inner peripheral surface 10a of cap 8 'and blood port (4, 5)
And the outer peripheral wall surface thereof is in close contact with the outer peripheral wall surface, thereby providing liquid tightness. On the other hand, the attachment to the dialysate-side ports (6, 7) is the same as in the first embodiment, and a description thereof will be omitted.

According to the caps 8 and 8 'according to the first and second embodiments, the blood side ports (4, 5) are fitted with air permeability or liquid tightness, and are fitted together. When fitted to the dialysate side port (6, 7) from one end A side, it is mounted with liquid tightness, and the dialysate side port (6, 7) is fitted.
7) from the other end B side, it is attached with air permeability, so it is possible to use blood caps (4, 5) with one type of cap.
And can be attached to the dialysate side port (6, 7),
In addition to facilitating inventory management, workability in mounting the cap 8 'to the dialyzer 9 can be improved. Further, since it is not necessary to prepare a plurality of types of caps, it is not necessary to prepare a plurality of types of molding dies, and the manufacturing cost can be reduced.

Although the present embodiment has been described above, the present invention is not limited to this. For example, instead of a dialyzer, another type of blood purifier (one having a blood-side port and another port) Limited to).

Further, the form of fitting to each port is not limited to that of the present embodiment, and it is possible to fit to one of the blood side port and the dialysate side port and mount it to the port. When fitted to the other port from one end side, it is mounted with liquid tightness, and when fitted to the other port from the other end side, it is fitted with air permeability. It may be a combined form.

[0039]

According to the present invention, the blood port and the dialysate port can be mounted in a single shape on the blood side port and the dialysate side port.
In addition to facilitating inventory control, improving workability in mounting to the dialyzer, manufacturing costs can be reduced.

[Brief description of the drawings]

FIG. 1 is a top view showing a cap according to a first embodiment of the present invention.

FIG. 2 is a bottom view showing the cap according to the first embodiment of the present invention.

FIG. 3 is a sectional view taken along line III-III in FIG. 2;

FIG. 4 is a sectional view taken along line IV-IV in FIG. 2;

FIG. 5 shows a state in which the cap according to the first embodiment of the present invention is attached to a dialyzer, and (a) a partial cross-section showing a state where the blood-side port and the dialysate-side port are fitted from the other end side. Figure, (b) Partial cross-sectional view showing a state fitted to the dialysate-side port from one end side

FIG. 6 is an enlarged view of a portion VI in FIG.

FIG. 7 is a partially enlarged view showing a state where the cap according to the first embodiment of the present invention is fitted to the blood port from the other end side.

FIG. 8 is a partially enlarged view showing a state where the cap according to the first embodiment of the present invention is fitted to the dialysate-side port from one end side.

FIG. 9 is a partially enlarged view showing a state in which the cap according to the first embodiment of the present invention is fitted to the dialysate-side port from the other end, and is a cross-sectional view taken along a reinforcing rib 12a.

FIG. 10 is a partially enlarged view showing a state in which the cap according to the first embodiment of the present invention is fitted to the dialysate-side port from the other end side, and is a cross-section at a position where there is no reinforcing rib 12a. Figure

FIG. 11 is a top view showing a cap according to a second embodiment of the present invention.

FIG. 12 is a side view showing a state in which a part of the cap according to the second embodiment of the present invention is partially cut away to show the inside;

FIG. 13 is a bottom view showing a cap according to a second embodiment of the present invention.

FIG. 14 is a partially enlarged view showing a state in which the cap according to the second embodiment of the present invention is fitted to the blood port from the other end side.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 ... Cylindrical casing 2 ... Hollow fiber membrane 3 ... Header 4 ... Blood introduction port (blood side port) 5 ... Blood outlet (blood side port) 6 ... Dialysate outlet (dialysate side port) 7 ... Dialysate introduction Mouth (dialysate side port) 8, 8 '... Cap 8a ... One end 8b ... Other end 8c ... Flange 9 ... Dialyzer 10a ... Inner peripheral surface 10b ... Outer peripheral surface 11 ... Rib 12 ... Rib 12a ... Reinforcing rib 12b ... Rib-less part 13 ... Groove 14 ... Concave part 15 ... Convex part 16 ... Sealing part 17 ... O-ring A ... One end B ... Other end

Claims (4)

[Claims] 1. A blood purifier cap mounted on each port of a blood purifier having a blood side port for introducing or discharging blood and a dialysate side port for introducing or discharging dialysate, Attached to one of the blood-side port and the dialysate-side port to be attachable to the port,
A blood purifier cap, wherein the cap is fitted with liquid tightness when fitted to the other port from one end, and is fitted with air permeability when fitted to the other port from the other end. 2. The blood purifier according to claim 1, wherein a plurality of hollow fiber membranes are loaded in a cylindrical casing to form a blood-side flow path formed by inner vesicles of each hollow fiber membrane and an outer periphery of the hollow fiber membrane. A dialysate-side flow path formed between the surface and the inner surface of the cylindrical casing and between adjacent hollow fiber membranes, wherein the blood-side port is for blood introduction and discharge of the blood-side flow path. And the dialysate-side port is
2. The blood purifier cap according to claim 1, wherein the port is a port for introducing and discharging a dialysate in the dialysate-side flow path. 3. The blood purifier cap according to claim 1, wherein said one port is said blood side port, and said other port is said dialysate side port. 4. A blood purifier wherein the cap according to any one of claims 1 to 3 is attached to the blood side port and the dialysate side port.