JP2001333960A - Dissolution liquid injection device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a dissolution liquid injection device which is capable of mixing an arbitrary medicine and a dissolution liquid, and moreover is easy in handling without fear of contaminating the medicine inside. SOLUTION: This dissolution liquid injection device contains a cylindrical adapter 1 having an upper opening 11 and a lower opening 12, and a two headed needle 2 which is tightly held slidably along the upper inner wall inside an inner wall of this adapter 1. On a lower inner wall of the adapter 1 are mounted more than one bentable connecting arms 13 which are set inclining toward inside in the direction from a lower end to an upper end, and a connecting protruded plate 14 mounted at a specified spacing from an upper side of this connecting arm 13. When a window of the dissolution liquid container is inserted into the lower opening 12 of the adapter 1, the window of the dissolution liquid container is sandwiched and fixed between the connecting arm 13 and the connecting protruded plate 14.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for connecting a solution container to a drug container, injecting the solution in the solution container into the drug container, and mixing the solution with the drug in the drug container to form a solution. It relates to a suitable lysis solution injection device.

[0002]

2. Description of the Related Art Conventionally, when a solution is prepared by mixing a solution and a drug at the time of use, a method of connecting a solution container and a drug container using a double-ended needle has been frequently used. A needle in which a needle is integrated into a solution container or a drug container (Japanese Utility Model Application Laid-Open No. 59-41424, Japanese Utility Model Application Laid-Open No.
No. 5642, JP-A-3-77557, JP-A-9-202364, etc., a dissolving solution container, a drug container and a double-ended needle are integrally incorporated so that they can be prepared aseptically (JP-A-Hei. 2-1277, JP-A-5-277
176970, JP-A-6-14973, etc.) have been proposed.

However, in the case where the above-mentioned double-ended needle is integrally incorporated in a dissolving solution container and / or a drug container, the dissolving solution container and / or the drug container are limited, and any drug and a dissolving solution (liquid (Including drugs). On the other hand, using a double-ended needle only to connect the dissolving solution container and the drug container and transferring the dissolving solution from the dissolving solution container to the drug container to dissolve the drug is a cumbersome and time-consuming operation, and also in the open air. Since the operation to make a hole in the container containing the medicine is performed, there is a possibility that the medicine inside may be contaminated,
It is a problem.

DISCLOSURE OF THE INVENTION The present invention has been made in view of the above circumstances, and can mix an arbitrary drug and a dissolving solution, is simple in operation, and contaminates the drug therein. It is an object of the present invention to provide a dissolving solution injection device without fear.

[0004]

Means for Solving the Problems The inventors of the present invention have made intensive studies to solve the above-mentioned problems, and as a result, have adopted an adapter for accommodating and holding a double-ended needle slidably along the inner wall thereof. The present invention was completed by conceiving that it should be easily mountable on a medicine container or a solution container at the time of use and can be firmly fixed so as not to fall off or wobble. That is, the present invention provides a cylindrical adapter having an upper end opening and a lower end opening, and having a lower end inner wall provided with means for fixing to the mouth of the solution container, and an upper end inner wall of the adapter extending along the inner wall. A double-ended needle slidably engaged and held, wherein the fixing means comprises a plurality of flexible engagement arms provided inclined inward from the lower end toward the upper end, and It consists of an abutment plate provided on the upper end side at a predetermined distance, and when the mouth of the solution container is inserted into the lower end opening of the adapter, the port of the solution container is located between the engaging arm and the abutment plate. The present invention relates to a dissolving solution injection device in which a portion is pinched and fixed.

Here, the double-ended needle has a cylindrical skirt having an upper end and a lower end, a disk-shaped hub which is unevenly distributed on the lower end side of the skirt and vertically partitions an inner space of the skirt, and a shaft of the hub. Preferably, the skirt comprises a puncture needle provided through the hub and provided with an annular rib near the lower end of the skirt. A kickback preventing rib for preventing kickback of the double-ended needle may be provided at a predetermined distance from the abutment plate of the adapter at a predetermined distance, and is engaged with the annular rib near the upper end of the adapter. Alternatively, a double-headed needle locking rib for releasably locking the double-ended needle may be provided.
Further, it is desirable to provide a slit in the skirt below the hub of the double-ended needle. The upper end opening of the adapter may be closed by a cap.

[0006]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Next, embodiments of the present invention will be described with reference to the drawings. FIG. 1 is a longitudinal sectional view showing an embodiment of the present invention. FIGS. 2 and 3 are longitudinal sectional views of an adapter and a double-ended needle shown in FIG. 1, respectively. 1 shows an embodiment of a cap according to the present invention. FIG. 5 is a diagram illustrating a method of using the dissolving solution injection device of the present invention. As shown in FIG. 1, the dissolving solution injection device according to the present invention includes a cylindrical adapter 1 having an upper end opening 11 and a lower end opening 12 and an inner wall at an upper end of the adapter 1 slidably along the inner wall. And a double-ended needle 2 held together. A plurality of flexible engagement arms 13 are provided on the inner wall at the lower end of the adapter 1 inclining inward from the lower end toward the upper end, and are provided at a predetermined distance from the engagement arm 13 to the upper end side. When the mouth of the solution container is inserted into the lower end opening 12 of the adapter 1, the mouth of the solution container is inserted between the engagement arm 13 and the collision plate 14. It is pinched and fixed.

[0007] The adapter 1 is a cylindrical member formed of a flexible resin such as polyethylene, polypropylene, polyester, or ABS resin, and has an upper end opening 11 and a lower end opening 12 as shown in FIG. A fixing means for fixing to the mouth of the solution container is provided on the inner wall at the lower end. This fixing means comprises a plurality of flexible engaging arms 13 and one or more abutting protruding plates 14, and the engaging arms 13 are provided to be inclined inward from the lower end toward the upper end. I have. Here, “inwardly inclined” refers to a state in which the tip of the engagement arm 13 is farthest from the inner wall of the adapter 1. The abutment protruding plate 14 is provided on the upper end side of the engaging arm 13 at a predetermined distance, and when the mouth of the dissolution liquid container S as shown in FIG. And the engagement arm 1
3 and the mouth is sandwiched and fixed.
In this case, the entire mouth portion may be held by the fixing means. However, when the flange F as shown in FIG. 5 is provided, the stroke is small, and the flange F is held. It is desirable to do so. The one shown in FIG. 2 is for clamping a flange with a small gap between the engagement arm 13 and the abutment plate 14. The abutment plate 14 may be a plurality of annularly arranged protrusions or a single flange. In short, the mouth of the solution container S is inserted into the lower end opening 12 of the adapter 1. In this case, any shape may be used as long as the opening of the solution container S can be sandwiched and fixed between the engaging solution arm 13 and the engaging arm 13.

The adapter 1 may be provided with a kickback preventing rib 15 on the upper end side of the abutment plate 14. The kickback preventing rib 15 is engaged with an annular rib 233 described later of the double-ended needle 2 so that the double-ended needle 2 pierced through the rubber stopper at the mouth of the solution container returns to the upper end side, that is, kickback. The distance between the abutment plate 14 and the lower end 23 of the skirt 23 of the double-ended needle 2 described later is
2 to be equal to the distance from the annular rib 233. The adapter 1 also engages with the annular rib 233 of the double-ended needle 2 near the upper end 231 thereof.
May be provided with a double-headed needle locking rib 16 for releasably locking. The double-ended needle locking rib 16 is a low small annular rib that can be securely engaged with the annular rib 233 of the double-ended needle 2 to hold the double-ended needle 2 and that the annular rib 233 can easily get over. Usually, two of the annular ribs 233 are provided at an interval slightly larger than the width of the annular rib 233 so as not to move to the upper end side or the lower end side due to transportation or the like. Note that a cap mounting portion 17 for mounting the cap 3 as shown in FIG. 4 may be provided at the upper end of the adapter 1 if necessary.

The double-ended needle 2 is formed of the same flexible resin as the adapter 1, and as shown in FIG. 3, forms a cylindrical skirt 23 having an upper end 231 and a lower end 232, and an inner space of the skirt 23. It comprises a disk-shaped hub 22 which is divided into upper and lower parts, and a puncture needle 21 provided on the axis of the hub 22 and penetrating through the hub 22. As the double-ended needle 2, it is desirable that the hub 22 is provided unevenly on the lower end side of the skirt 23 and the annular rib 233 is provided near the lower end 232 of the skirt 23. Further, the skirt 23 below the hub 22 is provided with a slit 234 that allows the skirt 23 to expand,
The annular rib 233 is the double-ended needle locking rib 17 of the adapter 1.
It is desirable to make it easy to get over the kickback preventing ribs 16. Here, 211 and 212 are fluid passages.

Next, a method of using the dissolving solution injection device of the present invention will be described with reference to FIG. The dissolving solution injection device to be used is one in which the upper end opening 11 of the adapter 1 is closed by the cap 3. First, as shown in FIG. 5, the dissolving solution injecting device is placed on a desk or the like with the cap 3 down, and then, for example, a saline container S as a dissolving solution container is inserted from the lower end opening 12, and the saline bottle S As shown in FIG. 5, the flange F of the mouth P
And the abutment plate 14, and is firmly fixed to the adapter 1. Next, the cap 3 is removed (see FIG. 5), the adapter 1 is grasped by hand, and the upper end opening 11 is pressed down at once at the mouth of the vial V, as shown in FIG. The medicine bottle V and the raw food bottle S communicate with each other via the double-ended needle 2, and the saline of the raw food bottle S is injected into the medicine bottle V. If the medicine bottle V is shaken well and the physiological saline and the medicine in the medicine bottle V are mixed to make a liquid, and the medicine bottle V is removed, the raw food bottle S can be used as it is as an infusion container, and the liquid medicine is transferred to a syringe or the like. Can also be used.

[0011]

As is apparent from the above description, the use of the dissolving solution injecting device of the present invention makes it possible to mix an arbitrary drug with a dissolving solution. Also, since the operation is simple, the trouble of performing the co-injection operation can be saved. Furthermore, since the solution container and the medicine container can be communicated with one operation, there is no possibility that the medicine inside is contaminated by the outside air.

[Brief description of the drawings]

FIG. 1 is a longitudinal sectional view showing an embodiment of the present invention.

FIG. 2 is a longitudinal sectional view of the adapter shown in FIG.

FIG. 3 is a longitudinal sectional view of the double-ended needle shown in FIG. 1;

FIG. 4 is a longitudinal sectional view showing an example of a cap suitable for closing an upper end opening of the adapter shown in FIG. 2;

FIG. 5 is a diagram illustrating a method of using the solution injection device of the present invention.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Adapter 11 Upper end opening 12 Lower end opening 13 Engagement arm 14 Butt plate 15 Kickback prevention rib 16 Double-headed needle locking rib 17 Cap mounting part 2 Double-ended needle 21 Puncturing needle 211, 212 Fluid passage 22 Hub 23 Skirt 231 Upper end 232 Lower end 233 Annular rib 234 Slit 3 Cap S S Solution container (saline bottle) F Flange V Drug container (Medicine bottle)

 ────────────────────────────────────────────────── ─── Continued on the front page (72) Inventor Kazushi Saruta 2-62-5 Nihonbashi Hamacho, Chuo-ku, Tokyo Inside Fujirebio Corporation

Claims (6)

[Claims] 1. A cylindrical adapter having an upper end opening and a lower end opening, and having a lower end inner wall provided with means for fixing to a mouth of a solution container, and an upper end inner wall of the adapter extending along the inner wall. A double-ended needle slidably engaged and held.
The fixing means comprises a plurality of flexible engagement arms provided inclining inward from the lower end toward the upper end, and an abutment plate provided at a predetermined distance from the engagement arm at an upper end side, A dissolving solution injecting device in which the dissolving solution container mouth is held between the engagement arm and the abutment plate when the mouth of the dissolving solution container is inserted into the lower end opening of the adapter. 2. A double-ended needle having a cylindrical skirt having an upper end and a lower end, a disk-shaped hub eccentrically located at a lower end side of the skirt to vertically define an inner space of the skirt, and a shaft on the hub. The injection device according to claim 1, further comprising a puncture needle provided through the hub, wherein an annular rib is provided near a lower end of the skirt. 3. The injection device according to claim 2, wherein a kickback preventing rib for preventing kickback of the double-ended needle is provided at a predetermined distance from the abutment plate of the adapter at a predetermined distance. 4. The injection device according to claim 2, wherein a double-ended needle locking rib is provided near the upper end of the adapter to engage with the annular rib and releasably lock the double-ended needle. 5. The injection device according to claim 2, wherein a slit is provided in the skirt below the hub of the double-ended needle. 6. The injection device according to claim 1, wherein an upper end opening of the adapter is closed by a cap.