JP2001137279A - Tape for medical care - Google Patents
Tape for medical careInfo
- Publication number
- JP2001137279A JP2001137279A JP32566499A JP32566499A JP2001137279A JP 2001137279 A JP2001137279 A JP 2001137279A JP 32566499 A JP32566499 A JP 32566499A JP 32566499 A JP32566499 A JP 32566499A JP 2001137279 A JP2001137279 A JP 2001137279A
- Authority
- JP
- Japan
- Prior art keywords
- adhesive layer
- pressure
- tape
- sensitive adhesive
- medical care
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000010410 layer Substances 0.000 claims abstract description 19
- 239000003242 anti bacterial agent Substances 0.000 claims abstract description 16
- 239000012790 adhesive layer Substances 0.000 claims abstract description 12
- 239000000463 material Substances 0.000 claims description 6
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 5
- 239000004925 Acrylic resin Substances 0.000 abstract description 4
- 229920000178 Acrylic resin Polymers 0.000 abstract description 4
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 abstract 1
- 238000003475 lamination Methods 0.000 abstract 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 18
- 239000000853 adhesive Substances 0.000 description 6
- 230000001070 adhesive effect Effects 0.000 description 6
- 229920001817 Agar Polymers 0.000 description 4
- 239000008272 agar Substances 0.000 description 4
- 239000004744 fabric Substances 0.000 description 4
- 244000043261 Hevea brasiliensis Species 0.000 description 3
- 239000000645 desinfectant Substances 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 229920003052 natural elastomer Polymers 0.000 description 3
- 229920001194 natural rubber Polymers 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 239000004599 antimicrobial Substances 0.000 description 2
- FUWUEFKEXZQKKA-UHFFFAOYSA-N beta-thujaplicin Chemical compound CC(C)C=1C=CC=C(O)C(=O)C=1 FUWUEFKEXZQKKA-UHFFFAOYSA-N 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical compound C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 229920002334 Spandex Polymers 0.000 description 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical compound C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- TUFYVOCKVJOUIR-UHFFFAOYSA-N alpha-Thujaplicin Natural products CC(C)C=1C=CC=CC(=O)C=1O TUFYVOCKVJOUIR-UHFFFAOYSA-N 0.000 description 1
- 150000003931 anilides Chemical class 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 239000003431 cross linking reagent Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- 125000001475 halogen functional group Chemical group 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 150000002460 imidazoles Chemical class 0.000 description 1
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 description 1
- 239000012948 isocyanate Substances 0.000 description 1
- 150000002513 isocyanates Chemical class 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 150000008379 phenol ethers Chemical class 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 150000003233 pyrroles Chemical class 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 239000004759 spandex Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 150000003457 sulfones Chemical class 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- 239000004308 thiabendazole Substances 0.000 description 1
- WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 description 1
- 229960004546 thiabendazole Drugs 0.000 description 1
- 235000010296 thiabendazole Nutrition 0.000 description 1
- 150000003558 thiocarbamic acid derivatives Chemical class 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
- 229930007845 β-thujaplicin Natural products 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
Abstract
Description
【0001】[0001]
【発明の属する技術分野】本発明は、医療用テープに関
する。[0001] The present invention relates to a medical tape.
【0002】[0002]
【従来の技術】従来の医療用テープとしては、救急絆創
膏、サージカルバン、ドレッシングテープ等が製品とし
て知られている。これらの医療用テープは、通常、布や
軟質フィルム等からなる基材層の一面にアクリル系樹脂
製糊や天然ゴム系糊等からなる粘着剤層が設けられ、そ
のままロール状に巻回されたり、必要によりガーゼ等の
吸収体を部分的に積層した上で離型紙によって保護され
た構成とされている。2. Description of the Related Art Emergency bandages, surgical vans, dressing tapes and the like are known as conventional medical tapes. These medical tapes are usually provided with an adhesive layer made of an acrylic resin glue or a natural rubber glue on one surface of a base material layer made of a cloth, a soft film, or the like, and may be wound as a roll. If necessary, an absorbent such as gauze is partially laminated, and is protected by release paper.
【0003】このような医療用テープの粘着剤層におい
て、雑菌が増殖することにより、接触している人体の傷
口の治癒を遅らせたり、甚だしい場合は傷を悪化させる
ことがあった。In the pressure-sensitive adhesive layer of such a medical tape, the growth of bacteria may delay the healing of the wound of the contacting human body, or worsen the wound in severe cases.
【0004】[0004]
【発明が解決しようとする課題】本発明は、上記従来の
医療用テープの問題点に鑑み、抗菌性を有する粘着剤層
を備えた医療用テープを提供することを目的とする。SUMMARY OF THE INVENTION An object of the present invention is to provide a medical tape having an antimicrobial pressure-sensitive adhesive layer in view of the above-mentioned problems of the conventional medical tape.
【0005】[0005]
【課題を解決するための手段】本発明の医療用テープ
は、基材層と粘着剤層との積層構造を有してなるもので
ある。基材層は、特に限定されず、例えば、伸縮性のあ
る布や軟質フィルム等から構成される。粘着剤層を形成
する粘着剤としては、従来より当該分野で使用されてい
る公知のものを採用できる。例えば、アクリル系、シリ
コーン系、天然ゴム系、合成ゴム系、ビニルエーテル系
等の単独もしくは2種以上のポリマーを主体に、必要に
応じて架橋剤、粘着付与剤、軟化剤、可塑剤、酸化防止
剤等を配合した粘着剤を挙げることが出来、これらの内
で特に、アクリル系粘着剤や天然ゴム系粘着剤が、耐久
性や経済性等の理由から好ましく用いられる。The medical tape of the present invention has a laminated structure of a base material layer and an adhesive layer. The substrate layer is not particularly limited, and is made of, for example, an elastic cloth or a soft film. As the pressure-sensitive adhesive forming the pressure-sensitive adhesive layer, a known pressure-sensitive adhesive conventionally used in this field can be employed. For example, a single or two or more polymers such as acrylic, silicone, natural rubber, synthetic rubber, vinyl ether, etc. are used as a main component, and if necessary, a crosslinking agent, a tackifier, a softener, a plasticizer, and an antioxidant are used. Examples thereof include pressure-sensitive adhesives containing an adhesive and the like. Among them, acrylic pressure-sensitive adhesives and natural rubber-based pressure-sensitive adhesives are particularly preferably used for reasons such as durability and economy.
【0006】また、粘着剤層には抗菌剤が必須成分とし
て含有されてなる。本発明において用いられる抗菌剤と
しては、特に限定されず、有機系抗菌剤、無機系抗菌剤
のいずれも使用可能である。The pressure-sensitive adhesive layer contains an antibacterial agent as an essential component. The antibacterial agent used in the present invention is not particularly limited, and any of an organic antibacterial agent and an inorganic antibacterial agent can be used.
【0007】有機系抗菌剤の例としては、イミダゾール
誘導体、フェノールエーテル誘導体N−ハロアルキルチ
オ系化合物、スルホン誘導体、アニリド誘導体 、ピロ
ール誘導体、フェノール系殺菌剤、トリアジン系殺菌
剤、第四級アンモニウム塩、尿素系殺菌剤、ポリアミド
系抗菌剤、チオカルバミン酸誘導体、チアベンダゾー
ル、ヒノキチオール等が挙げられ、無機系抗菌剤の例と
しては、金属イオン、抗菌性ゼオライト、酸化亜鉛等が
挙げられ、また、他に有機スズ系殺菌剤、有機銅系殺菌
剤、有機水銀系殺菌剤等が挙げられる。Examples of organic antibacterial agents include imidazole derivatives, phenol ether derivatives N-haloalkylthio compounds, sulfone derivatives, anilide derivatives, pyrrole derivatives, phenol fungicides, triazine fungicides, quaternary ammonium salts, Urea-based germicides, polyamide-based antibacterial agents, thiocarbamic acid derivatives, thiabendazole, hinokitiol, and the like.Examples of inorganic antibacterial agents include metal ions, antibacterial zeolites, zinc oxide, and the like. Organic tin-based disinfectants, organic copper-based disinfectants, organic mercury-based disinfectants, and the like.
【0008】粘着剤層に含有される抗菌剤の割合は、
0.01〜5重量%である。0.01重量%未満では抗
菌作用を実質的に発現することが出来ず、一方、5重量
%を越えると粘着剤層の粘着性を低下させる度合いが大
きく、医療用テープが患部から剥がれたり、基材が粘着
剤層から剥がれたりする不都合があるからである。抗菌
剤は、適宜の担持体に担持して、粘着剤層に分散含有さ
せて用いても良い。The ratio of the antibacterial agent contained in the pressure-sensitive adhesive layer is as follows:
It is 0.01 to 5% by weight. If the amount is less than 0.01% by weight, the antibacterial effect cannot be substantially exhibited, while if it exceeds 5% by weight, the degree of decrease in the adhesiveness of the adhesive layer is large, and the medical tape is peeled off from the affected area, This is because there is a disadvantage that the base material is peeled off from the pressure-sensitive adhesive layer. The antibacterial agent may be supported on a suitable carrier and used by being dispersed and contained in the pressure-sensitive adhesive layer.
【0009】本発明の医療用テープは、通常、基材層に
隣接して、アクリル系樹脂製等の粘着剤層が設けられて
おり、その下面には、シリコーン等からなる離型剤が塗
布された離型紙が積層されて構成されている。粘着剤層
と離型紙との間にガーゼ等が貼着されていても良い。基
材層の厚みは特に限定されず、通常、20〜500μm
程度とされる。過度に薄い場合は腰が不足して取扱い性
が悪くなることがあり、逆に厚過ぎると人体に対するな
じみが劣るようになり違和感が強くなることがある。The medical tape of the present invention is usually provided with an adhesive layer made of an acrylic resin or the like adjacent to the base material layer, and a release agent made of silicone or the like is applied to the lower surface thereof. Release papers are laminated. Gauze or the like may be adhered between the pressure-sensitive adhesive layer and the release paper. The thickness of the substrate layer is not particularly limited, and is usually 20 to 500 μm.
Degree. If the thickness is excessively thin, the waist may be insufficient and handleability may be deteriorated. On the other hand, if the thickness is excessively thick, familiarity with a human body may be reduced, and a sense of discomfort may be increased.
【0010】(実施例1〜4及び比較例1〜3)アクリ
ル系樹脂製粘着剤層における粘着剤として、イソシアネ
ート系の架橋タイプの粘着剤(綜研化学社製、「SK1
720」)、抗菌剤として金属銀を使用した。金属銀は
同量の酸化チタンに担持させ、粘着剤中の濃度が、表1
記載の通りとなる様に配合して、抗菌剤の粘着剤に対す
る相溶性を確認した。(Examples 1 to 4 and Comparative Examples 1 to 3) As a pressure-sensitive adhesive in an acrylic resin pressure-sensitive adhesive layer, an isocyanate-based crosslinkable pressure-sensitive adhesive (“SK1” manufactured by Soken Chemical Co., Ltd.)
720 "), and metallic silver was used as an antibacterial agent. Metallic silver was supported on the same amount of titanium oxide, and the concentration in the adhesive was as shown in Table 1.
The compounds were blended as described, and the compatibility of the antibacterial agent with the adhesive was confirmed.
【0011】基材1として、縦方向にスパンデックス、
横方向に綿糸を用いた縦方向伸縮基布を用意する一方、
離型紙上に、上記抗菌剤入りの粘着剤を乾燥後の厚みが
40μmとなる様に塗工し、100℃の温度で乾燥させ
た後、前記基布にこの粘着剤を転写し、粘着テープ化し
てこれを試験片とした。As the substrate 1, spandex in the longitudinal direction,
While preparing a vertical stretch base fabric using cotton yarn in the horizontal direction,
On the release paper, the above-mentioned adhesive containing the antibacterial agent is applied so as to have a thickness of 40 μm after drying, dried at a temperature of 100 ° C., and then transferred to the above-mentioned base cloth. This was used as a test piece.
【0012】特性評価方法 〔相溶性〕抗菌剤を粘着剤に添加攪拌し、攪拌10分後
の状態を観察し、沈殿もしくは白濁の有無を目視で判断
した。 〔粘着性〕上記試験片の粘着力を、常態及び40℃×1
ケ月の経時において評価し、その結果を表1に示した。 Characteristics evaluation method [Compatibility] An antibacterial agent was added to the adhesive, and the mixture was stirred. The state after 10 minutes of stirring was observed, and the presence or absence of precipitation or cloudiness was visually judged. [Adhesiveness] The adhesive strength of the test piece was measured under normal conditions and at 40 ° C. × 1.
Evaluation was performed over a period of five months, and the results are shown in Table 1.
【0013】〔抗菌性〕 (1)大腸菌(Escherichia coli IFO12734)をニュート
リエント培地(Nutrient broth)中で一晩前培養し、Nu
trient brothで1000倍希釈して菌数約10 6 個/ml
の菌液を調製し、シャーレ中に置いた寒天培地(Nutrie
nt agar )に100μl塗布した。 (2)上記試験片を、粘着剤層がagarに接する様にNutr
ient agar 上に置いて、シャーレの蓋をし、35℃で一
晩培養して、ハローの直径を測定することにより評価
し、その結果を表1に示した。粘着剤層中の抗菌剤の含
有率は、相溶性及び粘着性の評価結果から5重量%以下
であることが要請され、抗菌性の評価結果から0.01
重量%以上であることが要請されることが明らかであ
る。[Antibacterial] (1) Escherichia coli IFO12734
Pre-culture overnight in reent medium (Nutrient broth)
Dilute 1000 times with trient broth and count about 10 bacteria 6Pieces / ml
Agar medium (Nutrie) placed in a Petri dish
nt agar). (2) Put the test piece on Nutr so that the adhesive layer is in contact with the agar.
Place on a gent agar, cover the Petri dish, and store at 35 ° C.
Incubate overnight and evaluate by measuring halo diameter
The results are shown in Table 1. Including antimicrobial agent in the adhesive layer
The percentage is 5% by weight or less based on the evaluation results of compatibility and tackiness.
It is required to be 0.01
It is clear that it is required to be at least
You.
【0014】[0014]
【表1】 [Table 1]
【0015】[0015]
【発明の効果】本発明の医療用テープは、基材層と粘着
剤層との積層構造を有してなる医療用テープの前記粘着
剤層に、抗菌剤が0.01〜5重量%含有されてなるの
で、粘着剤層の良好な粘着性と抗菌性とを兼ね備えた、
実用的な効果の大なるものである。According to the medical tape of the present invention, the pressure-sensitive adhesive layer of the medical tape having a laminated structure of a base material layer and a pressure-sensitive adhesive layer contains 0.01 to 5% by weight of an antibacterial agent. Since it is made, it has both good adhesiveness and antibacterial property of the adhesive layer,
This is a great practical effect.
Claims (1)
なり、粘着剤層に、抗菌剤が0.01〜5重量%含有さ
れていることを特徴とする医療用テープ。1. A medical tape having a laminated structure of a base material layer and an adhesive layer, wherein the adhesive layer contains 0.01 to 5% by weight of an antibacterial agent.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP32566499A JP2001137279A (en) | 1999-11-16 | 1999-11-16 | Tape for medical care |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP32566499A JP2001137279A (en) | 1999-11-16 | 1999-11-16 | Tape for medical care |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2001137279A true JP2001137279A (en) | 2001-05-22 |
Family
ID=18179350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP32566499A Pending JP2001137279A (en) | 1999-11-16 | 1999-11-16 | Tape for medical care |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2001137279A (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003024494A1 (en) * | 2001-09-18 | 2003-03-27 | Bio-Gate Bioinnovative Materials Gmbh | Antimicrobial adhesive and coating substance and method for the production thereof |
JP2005154602A (en) * | 2003-11-26 | 2005-06-16 | Lintec Corp | Antibacterial pressure-sensitive adhesive product |
JP2006297075A (en) * | 2005-03-25 | 2006-11-02 | Nippon Shokubai Co Ltd | Adhesive material for skin and its manufacturing method |
JP2008136656A (en) * | 2006-12-01 | 2008-06-19 | Bando Chem Ind Ltd | Air permeable adhesive tape |
EP2165845A1 (en) | 2008-09-16 | 2010-03-24 | Ricoh Co., Ltd. | Thermosensitive recording medium with antibacterial property |
WO2010106004A1 (en) * | 2009-03-17 | 2010-09-23 | Sicurmatica Di Massimiliano Delli | Firm-hold acrylic-based adhesive for bonding hair prostheses to the skin |
JP2010215925A (en) * | 2010-06-21 | 2010-09-30 | Lintec Corp | Antibacterial adhesive product |
JP2011224396A (en) * | 2005-03-25 | 2011-11-10 | Nippon Shokubai Co Ltd | Skin adhesive material and method for manufacturing the same |
JP2014193818A (en) * | 2013-03-28 | 2014-10-09 | Dainippon Printing Co Ltd | Medical adhesive product |
-
1999
- 1999-11-16 JP JP32566499A patent/JP2001137279A/en active Pending
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003024494A1 (en) * | 2001-09-18 | 2003-03-27 | Bio-Gate Bioinnovative Materials Gmbh | Antimicrobial adhesive and coating substance and method for the production thereof |
US7476698B2 (en) | 2001-09-18 | 2009-01-13 | Bio-Gate Ag | Antimicrobial adhesive and coating substance and method for the production thereof |
JP2005154602A (en) * | 2003-11-26 | 2005-06-16 | Lintec Corp | Antibacterial pressure-sensitive adhesive product |
JP4567320B2 (en) * | 2003-11-26 | 2010-10-20 | リンテック株式会社 | Antibacterial adhesive products |
JP2006297075A (en) * | 2005-03-25 | 2006-11-02 | Nippon Shokubai Co Ltd | Adhesive material for skin and its manufacturing method |
JP2011224396A (en) * | 2005-03-25 | 2011-11-10 | Nippon Shokubai Co Ltd | Skin adhesive material and method for manufacturing the same |
JP2008136656A (en) * | 2006-12-01 | 2008-06-19 | Bando Chem Ind Ltd | Air permeable adhesive tape |
EP2165845A1 (en) | 2008-09-16 | 2010-03-24 | Ricoh Co., Ltd. | Thermosensitive recording medium with antibacterial property |
US8367581B2 (en) | 2008-09-16 | 2013-02-05 | Ricoh Company, Ltd. | Thermosensitive recording medium with antibacterial property |
WO2010106004A1 (en) * | 2009-03-17 | 2010-09-23 | Sicurmatica Di Massimiliano Delli | Firm-hold acrylic-based adhesive for bonding hair prostheses to the skin |
JP2010215925A (en) * | 2010-06-21 | 2010-09-30 | Lintec Corp | Antibacterial adhesive product |
JP2014193818A (en) * | 2013-03-28 | 2014-10-09 | Dainippon Printing Co Ltd | Medical adhesive product |
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