JP2000300583A - Denture stabilizer using fluorinated polymer - Google Patents

Abstract

PROBLEM TO BE SOLVED: To make a denture stabilizer usable continuously for several weeks to several months or for a much longer period by using a fluorinated polymer having good water resistance, oil resistance, pollution resistance and chemical stability as a denture stabilizer. SOLUTION: A denture stabilizer is prepared by using a fluorinated polymer having good water resistance, oil resistance, pollution resistance and chemical stability. Since is denture stabilizer does not contain a plasticizer, it is non- stimulative and can be used continuously for an extended period. The denture stabilizer may be prepared by dissolving a fluorinated polymer in an acrylic monomer, adding a polymerization initiator and then polymerizing and hardening the added monomer. The fluorinated polymer to be used may be a vinylidene fluoride copolymer, a fluoroalkene/olefin copolymer, a fluoro (alkylvinylether)/ olefin copolymer, or a fluorosilicone elastomer.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a denture stabilizer composition used for fixing a denture.

[0002]

2. Description of the Related Art A denture stabilizer is an agent for temporarily fixing an incompatible denture caused by absorption or deformation of a chin support with aging to an oral mucosa and supplementing its function. Currently marketed denture stabilizers are roughly classified into two types. One is the "adhesion type" in which a rubber paste-like preparation with cushions mainly composed of vinyl acetate and ethanol is buried in the gap between the denture base and the mucous membrane and the denture is vacuum-adsorbed to the mucous membrane. Close contact type is the mainstream of denture stabilizer. The other is karaya gum,
Natural substances such as gum arabic and tragacanth, and synthetic or semi-synthetic polymers such as sodium alginate, sodium carboxymethylcellulose, metal salts of polyacrylic acid, polyethylene oxide, and polyvinylpyrrolidone are used alone or in combination of two or more. It is a "adhesive type" that uses a polymer as the main agent and absorbs saliva in the mouth between the denture base and the mucous membrane to exhibit adhesiveness and sticks the denture to the mucous membrane.

[0003] In addition to the function of fixing the denture by being rubber-like, the close contact type functions as a cushioning material that relieves pain caused by irritation caused by the incompatibility of the denture in contact with the gingiva or mucous membrane during mastication. Also have. However, since this type contains vinyl acetate as a main base and ethanol as a plasticizer, it is irritating to mucous membranes and may be harmful to the human body. Furthermore, even if it can be used continuously for several days (2 to 3 days), since the components contain ethanol and water, the denture stabilizer is deteriorated due to elution. Furthermore, bacteria such as Candida bacteria in the oral cavity also easily proliferate, and the hygiene condition in the oral cavity tends to deteriorate.
In spite of the demand for long-term use, it is currently impossible to continue using for several days or more for the above reasons.
In addition, after the dissolution of ethanol as a plasticizer, strong adhesion between the denture and the denture stabilizer occurs, and its removal is extremely difficult.
There have been many studies to improve this. (JP-A-61-73648, JP-A-62-129210, JP-A-1-180807, JP-A-2-124808, JP-A-2-292207, JP-A-4-149110, JP-A-5-149110
-65210, JP-A-5-65210, JP-A-6-65
211, JP-A-11-253466)

[0004] The adhesive type cannot expect a cushioning effect like the close contact type in the form of a rubber paste, and the preparation elutes and is lost during use, so that the use period is limited to one day. In addition, it can be used for well-fitting dentures or light dentures with a small degree of non-conformity (the gap between the gingiva and denture is small), but it is difficult to use dentures with a large degree of non-conformity. Furthermore, there is a disadvantage that the user feels uncomfortable feeling and unpleasant taste such as sticky and sticky due to elution.

At present, there are three types of soft materials related to dentures: denture stabilizers, dental mucosal conditioners, and soft dental lining materials, all of which are used for purposes, methods, periods of use, and required properties. Etc. are different. The denture stabilizer is intended to be used by the patient himself and temporarily used for a very short period of one to several days. In contrast, mucosal conditioners,
All soft lining materials are treated by a dentist. The mucosal conditioner is used as a treatment for restoring the distorted oral mucosa to a normal state (JP-A-11-318946), and the soft lining material is a material for repairing a denture (JP-A-55-2).
1919, Japanese Patent Application Laid-Open No. 62-192153), so that it will be used for a long time after repair. Although the above three types of materials are denture-related materials, their classifications are clearly different depending on the purpose of use and required performance. In Japan, dentists have generally taken a critical stance on the close-fitting type with cushioning properties, which is the mainstream of denture stabilizers. The reason is that when a denture stabilizer of the close contact type is used, the chin support may be severely damaged, remarkable absorption occurs in the chin support in a short period of time, and the oral hygiene condition is significantly deteriorated. Therefore, at present, the denture wearer himself purchases and uses it directly, and its use is out of the control of the dentist in principle.

[0006] In Japan, the sales of denture stabilizers are about 8 billion yen per year, and in the United States 1996-1997.
Was more than $ 200 million. Despite the fact that many dentists are critical of their use, denture wearers are dissatisfied with the dentures they are using and are currently purchasing and performing the procedure. Given the aging society of Japan in recent years,
It is expected to be used by caregivers in nursing homes, nursing homes, or homes, and the demand is expected to increase in the future. In such a current situation, inventions have been awaited that can be used continuously and have no functional or hygienic problems beyond conventional common sense of denture stabilizers.

[0007]

A denture stabilizer which can be used only for one day to several days at present can be used continuously for a period of several weeks to several months or more, and it can function and be used well. It is to improve.

[0008]

Means for Solving the Problems The present inventors have made intensive studies to solve the above problems, and as a result, focused on the water resistance, oil resistance, stain resistance, and chemical stability of the fluoropolymer, By using this, it has been found that a denture stabilizer that is not irritating because it does not contain a plasticizer, is a conventional adhesive type, and can be used continuously for a long time can be obtained, and has completed the present invention. .

[0009]

BEST MODE FOR CARRYING OUT THE INVENTION The fluoropolymer used in the present invention includes, for example, vinylidene fluoride copolymer, fluoroalkene / olefin copolymer, fluoro (alkyl vinyl ether) Including olefin-based copolymers,
Fluorosilicone elastomers, fluorophosphazene elastomers and the like can be mentioned. As the above-mentioned fluoropolymer, a low molecular weight polymer having a molecular weight of 2,000 to 800,000 is desirable. The use of the fluoropolymer is not limited to one kind, and two or more kinds may be used in combination.

In the present invention, the fluorine-based polymer used in the present invention needs to be soluble in an acrylic monomer. For example, vinylidene fluoride / hexafluoropropylene, vinylidene fluoride / tetrafluoroethylene / hexaene can be used. Fluoropropylene-based,
Vinylidene fluoride-based copolymers such as vinylidene fluoride / chlorotrifluoroethylene-based copolymers may be mentioned, and among them, some of them have an iodine atom or a bromine atom bonded to the polymer chain, 53-125
No. 491, JP-B-53-4115, JP-A-59-20
No. 310) It is preferable in increasing the polymerization reactivity of the monomer. In the present invention of claim 2, the type of acrylic monomer is not limited, but mono- or polyfunctional ones are included, and one or more types are used, and the polyfunctional monomer is used in combination with the monofunctional monomer. It is preferable to use a small amount. Examples of these include methyl methacrylate (MM
A), ethyl methacrylate (EMA), butyl methacrylate (BMA) and the like. The monomer is added to adjust the flowability of the polymerized and cured product mainly, and the weight% of the polymerized and cured product is 2 to 2.
It is preferably about 20%, and the main ingredient of the denture stabilizer according to the present invention of claim 2 is a fluoropolymer. In the second aspect of the present invention, the fluoropolymer is sufficiently dissolved in the additional monomer, and then the additional monomer is polymerized and cured. There are no particular restrictions on the polymerization method, and heat, light, a chemical catalyst at room temperature, or the like can be used as the polymerization initiation source. Then, the obtained polymerized and cured product is used as a denture stabilizer.

[0010]

EXAMPLES The present invention will be described in more detail with reference to Examples, but the present invention is not limited to these Examples. Unless otherwise specified, "%" indicates weight "%".

Example 1: A copolymer of vinylidene fluoride and hexafluoropropylene (molecular weight: about 3000) as a fluoropolymer was directly used as a denture stabilizer. Upon mastication, appropriate fluidity was confirmed, and the subject also recognized an improvement in denture wearing feeling.

Example 2: 88% of a copolymer (molecular weight: about 3000) composed of vinylidene fluoride and hexafluoropropylene as a fluorine-based polymer, and C as a polymerization initiator
Q, (Camphorquinone), and DMAEMA (dimethylaminoethyl methacrylate) were adjusted to 12% as a monomer using ethyl methacrylate to which 1% was added, respectively, and left until the polymer was sufficiently dissolved in the monomer. Then, the visible light was sufficiently irradiated by a visible light irradiator to sufficiently polymerize and cure the monomer. This polymerized cured product was used as a denture stabilizer for non-conforming dentures of the subject, and was put on a commercially available denture cleaner at night before bedtime, so that it could be used continuously. Weekly continuous use was sufficiently possible.

Example 3: 88% of a copolymer (molecular weight: about 3000) composed of vinylidene fluoride and hexafluoropropylene as a fluorine-based polymer,
2% of a copolymer (molecular weight: about 50,000) in which iodine is bonded to hexafluoropropylene, and the polymerization initiator is Example 2
In the same manner as in Example 2, the amount of ethyl methacrylate added was adjusted to be 10% as a monomer, and a polymerized and cured product was produced in the same manner as in Example 2. This polymerized cured product was used as a denture stabilizer for non-conforming dentures of subjects, and was continuously used by putting it on a commercially available denture cleanser every night before going to bed, but there were no functional or sanitary problems. Weekly continuous use was sufficiently possible.

【The invention's effect】

The above-mentioned properties of the fluoropolymer such as water resistance, oil resistance, stain resistance and chemical stability are considered to be optimal in consideration of the oral environment. A conventional close contact type denture stabilizer uses ethanol as a plasticizer, but the product of the present invention does not contain a plasticizer at all, and it is easy to remove the denture stabilizer after use. In addition, it has become possible to continue using denture stabilizers that can only be used for a few days until now, exceeding common sense. The present invention, which focuses on fluoropolymers which have not been considered as a material for denture stabilizers at all, and has conceived its use, is an epoch-making.

Claims (2)

[Claims] 1. Use of a fluoropolymer as a denture stabilizer. 2. A denture stabilizer prepared by dissolving a fluorine-based polymer in an acrylic monomer, adding a polymerization initiator, and then polymerizing and curing the added monomer.