JOP20190038B1 - A composition of multivalent pneumococcal capsular polysaccharide-carrier protein conjugates and use thereof - Google Patents

A composition of multivalent pneumococcal capsular polysaccharide-carrier protein conjugates and use thereof

Info

Publication number
JOP20190038B1
JOP20190038B1 JOP/2019/0038A JOP20190038A JOP20190038B1 JO P20190038 B1 JOP20190038 B1 JO P20190038B1 JO P20190038 A JOP20190038 A JO P20190038A JO P20190038 B1 JOP20190038 B1 JO P20190038B1
Authority
JO
Jordan
Prior art keywords
carrier protein
capsular polysaccharide
composition
protein conjugates
pneumococcal capsular
Prior art date
Application number
JOP/2019/0038A
Other languages
Arabic (ar)
Inventor
Hoon Sung Jeh
Tae Hyun Kim
Original Assignee
Lg Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Chemical Ltd filed Critical Lg Chemical Ltd
Publication of JOP20190038A1 publication Critical patent/JOP20190038A1/en
Application granted granted Critical
Publication of JOP20190038B1 publication Critical patent/JOP20190038B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to a vaccine composition for preventing pneumococcal diseases and an immunogenic composition against Streptococcus pneumoniae, which contains 13 or 14 types of capsular polysaccharide-carrier protein conjugates.
JOP/2019/0038A 2016-09-06 2017-08-31 A composition of multivalent pneumococcal capsular polysaccharide-carrier protein conjugates and use thereof JOP20190038B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20160114591 2016-09-06
PCT/KR2017/009569 WO2018048141A1 (en) 2016-09-06 2017-08-31 Composition comprising multivalent capsular polysaccharide-transport protein and use thereof

Publications (2)

Publication Number Publication Date
JOP20190038A1 JOP20190038A1 (en) 2019-03-06
JOP20190038B1 true JOP20190038B1 (en) 2023-09-17

Family

ID=61561397

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2019/0038A JOP20190038B1 (en) 2016-09-06 2017-08-31 A composition of multivalent pneumococcal capsular polysaccharide-carrier protein conjugates and use thereof

Country Status (12)

Country Link
KR (1) KR101991457B1 (en)
BR (1) BR112019004303A2 (en)
EA (1) EA201990451A1 (en)
JO (1) JOP20190038B1 (en)
MA (1) MA45283B1 (en)
MX (1) MX2019002552A (en)
MY (1) MY192792A (en)
PH (1) PH12019500377A1 (en)
SA (1) SA519401232B1 (en)
TN (1) TN2019000064A1 (en)
WO (1) WO2018048141A1 (en)
ZA (1) ZA201901969B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111683678B (en) 2017-12-06 2024-01-26 默沙东有限责任公司 Compositions comprising Streptococcus pneumoniae polysaccharide protein conjugates and methods of use thereof
KR102486891B1 (en) 2018-02-05 2023-01-10 사노피 파스퇴르 인코포레이티드 Polyvalent pneumococcal polysaccharide-protein conjugate composition
CA3096358A1 (en) * 2018-04-18 2019-10-24 Sk Bioscience Co., Ltd. Streptococcus pneumoniae capsular polysaccharide and immunogenic conjugate thereof
TWI788610B (en) 2018-12-19 2023-01-01 美商默沙東有限責任公司 Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
WO2023218322A1 (en) * 2022-05-11 2023-11-16 Pfizer Inc. Process for producing of vaccine formulations with preservatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE254475T1 (en) * 1993-09-22 2003-12-15 Jackson H M Found Military Med METHOD FOR ACTIVATION OF SOLUBLE CARBOHYDRATES BY USING NEW CYANYLATION REAGENTS TO PRODUCE IMMUNOGENIC CONSTRUCTS
KR20150061019A (en) * 2005-04-08 2015-06-03 와이어쓰 엘엘씨 Multivalent pneumococcal polysaccharide-protein conjugate composition
HUE048398T2 (en) * 2010-06-04 2020-07-28 Wyeth Llc Vaccine formulations
KR102057217B1 (en) * 2012-06-20 2020-01-22 에스케이바이오사이언스 주식회사 Multivalent pneumococcal polysaccharide-protein conjugate composition
CN103893751B (en) * 2014-03-26 2016-04-20 天津康希诺生物技术有限公司 A kind of pneumococal polysaccharide Protein Conjugation vaccine and preparation method thereof
CN104069504B (en) * 2014-05-11 2019-09-24 江苏康泰生物医学技术有限公司 A method of enhancing polysaccharide protein conjugate immunogenicity

Also Published As

Publication number Publication date
EA201990451A1 (en) 2019-08-30
MY192792A (en) 2022-09-09
SA519401232B1 (en) 2022-10-23
MX2019002552A (en) 2019-07-01
MA45283B1 (en) 2021-05-31
ZA201901969B (en) 2019-12-18
TN2019000064A1 (en) 2020-07-15
MA45283A1 (en) 2019-06-28
KR101991457B1 (en) 2019-09-30
WO2018048141A1 (en) 2018-03-15
BR112019004303A2 (en) 2019-05-28
PH12019500377A1 (en) 2019-10-21
KR20180027353A (en) 2018-03-14
JOP20190038A1 (en) 2019-03-06

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