JOP20180105A1 - Process for the preparation of (s)-n-(5-((r)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide and salts thereof - Google Patents

Process for the preparation of (s)-n-(5-((r)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide and salts thereof

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Publication number
JOP20180105A1
JOP20180105A1 JOP/2018/0105A JOP20180105A JOP20180105A1 JO P20180105 A1 JOP20180105 A1 JO P20180105A1 JO P20180105 A JOP20180105 A JO P20180105A JO P20180105 A1 JOP20180105 A1 JO P20180105A1
Authority
JO
Jordan
Prior art keywords
hydroxypyrrolidine
pyrazolo
difluorophenyl
pyrrolidin
pyrimidin
Prior art date
Application number
JOP/2018/0105A
Other languages
Arabic (ar)
Inventor
Bruno Hache
Steven W Andrews
Yutong Jiang
Stacey Spencer
Mark Reynolds
Julia Haas
Charles Todd Eary
Derrick Juengst
Original Assignee
Loxo Oncology Inc
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Loxo Oncology Inc, Array Biopharma Inc filed Critical Loxo Oncology Inc
Priority to JOP/2018/0105A priority Critical patent/JOP20180105B1/en
Publication of JOP20180105A1 publication Critical patent/JOP20180105A1/en
Application granted granted Critical
Publication of JOP20180105B1 publication Critical patent/JOP20180105B1/en

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Abstract

In some embodiments, provided herein is a process for preparing a compound of Formula I Formula I or a salt thereof, as disclosed herein.
JOP/2018/0105A 2018-11-15 2018-11-15 Preparation of (s)-n-(5-((r)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide JOP20180105B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JOP/2018/0105A JOP20180105B1 (en) 2018-11-15 2018-11-15 Preparation of (s)-n-(5-((r)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JOP/2018/0105A JOP20180105B1 (en) 2018-11-15 2018-11-15 Preparation of (s)-n-(5-((r)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

Publications (2)

Publication Number Publication Date
JOP20180105A1 true JOP20180105A1 (en) 2020-05-15
JOP20180105B1 JOP20180105B1 (en) 2022-03-14

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Application Number Title Priority Date Filing Date
JOP/2018/0105A JOP20180105B1 (en) 2018-11-15 2018-11-15 Preparation of (s)-n-(5-((r)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

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Country Link
JO (1) JOP20180105B1 (en)

Also Published As

Publication number Publication date
JOP20180105B1 (en) 2022-03-14

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