JO3333B1 - استعمال 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium أو ملح مقبول دوائيا منه للوقاية من السكري وعلاجه - Google Patents
استعمال 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium أو ملح مقبول دوائيا منه للوقاية من السكري وعلاجهInfo
- Publication number
- JO3333B1 JO3333B1 JOP/2014/0244A JOP20140244A JO3333B1 JO 3333 B1 JO3333 B1 JO 3333B1 JO P20140244 A JOP20140244 A JO P20140244A JO 3333 B1 JO3333 B1 JO 3333B1
- Authority
- JO
- Jordan
- Prior art keywords
- dimethylpropan
- aminium
- carboxy
- ethyl
- pharmaceutically acceptable
- Prior art date
Links
- ISMYCKWHOZKHNJ-UHFFFAOYSA-O 3-carboxypropyl-ethyl-dimethylazanium Chemical compound CC[N+](C)(C)CCCC(O)=O ISMYCKWHOZKHNJ-UHFFFAOYSA-O 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 230000037058 blood plasma level Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
يتعلق الاختراع الحالي باستخدام 3- كربوكسي -N- إيثيل -N، N- داي ميثيل بروبان -1- أمينيوم وأملاح مقبولة صيدلانياً منه لتقليل مستويات الأنسولين والجلوكوز في بلازما الدم.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13186201 | 2013-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO3333B1 true JO3333B1 (ar) | 2019-03-13 |
Family
ID=49231372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOP/2014/0244A JO3333B1 (ar) | 2013-09-26 | 2014-08-05 | استعمال 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium أو ملح مقبول دوائيا منه للوقاية من السكري وعلاجه |
Country Status (9)
| Country | Link |
|---|---|
| CN (1) | CN105530929B (ar) |
| AR (1) | AR099638A1 (ar) |
| BR (1) | BR112016004211B1 (ar) |
| CA (1) | CA2924682C (ar) |
| JO (1) | JO3333B1 (ar) |
| MX (1) | MX368505B (ar) |
| TN (1) | TN2016000064A1 (ar) |
| WO (1) | WO2015044828A1 (ar) |
| ZA (1) | ZA201600894B (ar) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2067474A1 (en) * | 2007-12-05 | 2009-06-10 | Grindeks, a joint stock company | Medical use of 3-(2,2,2-trimethylhydrazinium) propionate hydrogen fumarate |
| LV14345B (lv) | 2009-10-22 | 2011-07-20 | Grindeks, A/S | 4-[Etil(dimetil)amonija]butanoāts un tā izmantošana kardiovaskulāro slimību ārstēšanai |
| CN103608326B (zh) * | 2011-04-27 | 2016-01-20 | 格林代克斯联合股份公司 | 3-羧基-n-乙基-n,n-二甲基丙-1-铵盐在治疗心血管疾病中的用途 |
-
2014
- 2014-08-05 JO JOP/2014/0244A patent/JO3333B1/ar active
- 2014-08-13 AR ARP140103039A patent/AR099638A1/es unknown
- 2014-09-15 CN CN201480050485.3A patent/CN105530929B/zh active Active
- 2014-09-15 TN TN2016000064A patent/TN2016000064A1/en unknown
- 2014-09-15 MX MX2016003347A patent/MX368505B/es active IP Right Grant
- 2014-09-15 WO PCT/IB2014/064514 patent/WO2015044828A1/en not_active Ceased
- 2014-09-15 CA CA2924682A patent/CA2924682C/en active Active
- 2014-09-15 BR BR112016004211-5A patent/BR112016004211B1/pt active IP Right Grant
-
2016
- 2016-02-09 ZA ZA2016/00894A patent/ZA201600894B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TN2016000064A1 (en) | 2017-07-05 |
| CN105530929A (zh) | 2016-04-27 |
| MX2016003347A (es) | 2016-06-24 |
| MX368505B (es) | 2019-10-04 |
| CN105530929B (zh) | 2018-03-02 |
| BR112016004211A2 (ar) | 2017-08-01 |
| ZA201600894B (en) | 2017-05-31 |
| AR099638A1 (es) | 2016-08-10 |
| CA2924682A1 (en) | 2015-04-02 |
| BR112016004211B1 (pt) | 2022-09-06 |
| CA2924682C (en) | 2018-02-27 |
| WO2015044828A1 (en) | 2015-04-02 |
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