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The present invention pertains to a sized product, which contains a drug polyethylene oxide with a molecular weight of 2.000.000 or higher, and a specific size controlling agent for polyethylene oxide( substance with the appropriate plasticity and binding force) and wherein at least the above-mentioned specific size controlling agent is uniformly dispersed in the above –mentioned polyethylene oxide, a controlled – release pharmaceutical composition containing this sized product, and a method of manufacturing a controlled release pharmaceutical containing this sized product A controlled release pharmaceutical composition with good uniformity of content can be presented by using powder particles of polyethylene oxide with powder properties suitable for tableting, which is obtained by uniform dispersion of the specific size controlling agent for polyethylene oxide of the present invention
JO200425A2003-03-062004-03-07Pharmaceutical composition for controlled release of active substances and the manufacturing method thereof
JO2921B1
(en)
COMPOSITION AND METHOD FOR THE PREPARATION OF A NANOPARTICULATE cephalosporin, FOR THE TREATMENT OF BACTERIAL DISEASE AND FOR THE PREVENTION AND/OR TREATMENT OF OSTEOPOROSIS