JO2694B1 - Benzoimidazol-2-YL Pyrimidines And Pyrazines As Modulators Of The Histamine H4 Receptor - Google Patents
Benzoimidazol-2-YL Pyrimidines And Pyrazines As Modulators Of The Histamine H4 ReceptorInfo
- Publication number
- JO2694B1 JO2694B1 JO200785A JOP20070085A JO2694B1 JO 2694 B1 JO2694 B1 JO 2694B1 JO 200785 A JO200785 A JO 200785A JO P20070085 A JOP20070085 A JO P20070085A JO 2694 B1 JO2694 B1 JO 2694B1
- Authority
- JO
- Jordan
- Prior art keywords
- pyrazines
- pyrimidines
- receptor
- benzoimidazol
- histamine
- Prior art date
Links
- WTZRQYJHRXQWTK-UHFFFAOYSA-N 2-pyrimidin-2-yl-1h-benzimidazole Chemical class N=1C2=CC=CC=C2NC=1C1=NC=CC=N1 WTZRQYJHRXQWTK-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003216 pyrazines Chemical class 0.000 title abstract 2
- 102000004187 Histamine H4 receptors Human genes 0.000 title 1
- 108090000796 Histamine H4 receptors Proteins 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Benzimidazol-2-yl pyrimidines and pyrazines, pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, including allergy,asthma, autoimmune diseases, and pruritis.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19078806P | 2006-03-31 | 2006-03-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO2694B1 true JO2694B1 (en) | 2013-03-03 |
Family
ID=51301005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JO200785A JO2694B1 (en) | 2006-03-31 | 2007-03-26 | Benzoimidazol-2-YL Pyrimidines And Pyrazines As Modulators Of The Histamine H4 Receptor |
Country Status (1)
| Country | Link |
|---|---|
| JO (1) | JO2694B1 (en) |
-
2007
- 2007-03-26 JO JO200785A patent/JO2694B1/en active
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