JO2467B1 - New indole derivatives as factor Xa inhibitors - Google Patents

New indole derivatives as factor Xa inhibitors

Info

Publication number
JO2467B1
JO2467B1 JO200339A JOP20030039A JO2467B1 JO 2467 B1 JO2467 B1 JO 2467B1 JO 200339 A JO200339 A JO 200339A JO P20030039 A JOP20030039 A JO P20030039A JO 2467 B1 JO2467 B1 JO 2467B1
Authority
JO
Jordan
Prior art keywords
factor
compounds
formula
inhibitors
factor viia
Prior art date
Application number
JO200339A
Other languages
Arabic (ar)
Inventor
ديفيد ويليام ويل د.
هانز ماتر د.
كيرت ريتر د.
مارك نازادي د.
فولكمار ويهنر د.
إسريتش ميلاني
Original Assignee
سانوفي- افانتس دوتشلاند جي ام بي اتش
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by سانوفي- افانتس دوتشلاند جي ام بي اتش filed Critical سانوفي- افانتس دوتشلاند جي ام بي اتش
Priority to JO200339A priority Critical patent/JO2467B1/en
Application granted granted Critical
Publication of JO2467B1 publication Critical patent/JO2467B1/en

Links

Abstract

The present invention relates to compounds of the formula I, in which R0;R1;R2 ;R3 ; R4 ; R5; R6;R7;Q; V; G and M have the meanings indicated in the claims. The compounds of the formula I are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses. They are reversible inhibitors of the blood clotting enzymes factor Xa (FXa) and/or factor VIIa (FVIIa), and can in general be applied in conditions in which an undesired activity of factor Xa and/or factor VIIa is present or for the cure or prevention of which an inhibition of factor Xa and/or factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of the formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them
JO200339A 2003-04-08 2003-04-08 New indole derivatives as factor Xa inhibitors JO2467B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JO200339A JO2467B1 (en) 2003-04-08 2003-04-08 New indole derivatives as factor Xa inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JO200339A JO2467B1 (en) 2003-04-08 2003-04-08 New indole derivatives as factor Xa inhibitors

Publications (1)

Publication Number Publication Date
JO2467B1 true JO2467B1 (en) 2009-01-20

Family

ID=48040990

Family Applications (1)

Application Number Title Priority Date Filing Date
JO200339A JO2467B1 (en) 2003-04-08 2003-04-08 New indole derivatives as factor Xa inhibitors

Country Status (1)

Country Link
JO (1) JO2467B1 (en)

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