JO2237B1 - Derivatives of monosaccharides as cell adhesion inhibitors - Google Patents
Derivatives of monosaccharides as cell adhesion inhibitorsInfo
- Publication number
- JO2237B1 JO2237B1 JO200046A JOP20000046A JO2237B1 JO 2237 B1 JO2237 B1 JO 2237B1 JO 200046 A JO200046 A JO 200046A JO P20000046 A JOP20000046 A JO P20000046A JO 2237 B1 JO2237 B1 JO 2237B1
- Authority
- JO
- Jordan
- Prior art keywords
- cell adhesion
- derivatives
- monosaccharides
- xylo
- isopropylidene
- Prior art date
Links
- 230000021164 cell adhesion Effects 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 150000002772 monosaccharides Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000007170 pathology Effects 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 230000017455 cell-cell adhesion Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 239000008196 pharmacological composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-O-isopropylidene-a-L-xylo-2-hexulofuranosonic acid. The compounds of this invention are useful, inter-alia, for the inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies, including inflammatory and autoimmune diseases, such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection and psoriasis. This invention also relates to pharmacological compositions containing derivatives of 2-3-O-isopropylidene-a-L-xylo-2-hexulofuranosonic acid and the methods of treating such pathologies as listed above.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JO200046A JO2237B1 (en) | 2000-04-11 | 2000-04-11 | Derivatives of monosaccharides as cell adhesion inhibitors |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JO200046A JO2237B1 (en) | 2000-04-11 | 2000-04-11 | Derivatives of monosaccharides as cell adhesion inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO2237B1 true JO2237B1 (en) | 2004-10-07 |
Family
ID=48052138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JO200046A JO2237B1 (en) | 2000-04-11 | 2000-04-11 | Derivatives of monosaccharides as cell adhesion inhibitors |
Country Status (1)
| Country | Link |
|---|---|
| JO (1) | JO2237B1 (en) |
-
2000
- 2000-04-11 JO JO200046A patent/JO2237B1/en active
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