JO2058B1 - New derivatives of echinocandine, their preparation process and their use as fungicides - Google Patents
New derivatives of echinocandine, their preparation process and their use as fungicidesInfo
- Publication number
- JO2058B1 JO2058B1 JO19982058A JOP19982058A JO2058B1 JO 2058 B1 JO2058 B1 JO 2058B1 JO 19982058 A JO19982058 A JO 19982058A JO P19982058 A JOP19982058 A JO P19982058A JO 2058 B1 JO2058 B1 JO 2058B1
- Authority
- JO
- Jordan
- Prior art keywords
- echinocandine
- fungicides
- preparation process
- new derivatives
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
Abstract
The invention concerns compounds of formula (I) in which: either R1 and R2 = H, OH, alkyl optionally substituted, or NR1 forms with the carbon bearing NR1R2 a double bond and R2 is Xra, X being O, NH or N-alkyl and Ra being H, alkyl optionally substituted; R = a chain containing up to 10 carbon atoms, optionally comprising one or several heteroatoms, one or several heterocycles, T = H, CH2, CH2CONH2, CH2CN, (CH2)2NH2; Y = H, OH, halogen; W = H, OH; Z = H OR CH3. The products have anti-fungal properties.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9715628A FR2772028B1 (en) | 1997-12-10 | 1997-12-10 | NOVEL ECHINOCANDIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS FUNGICIDES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO2058B1 true JO2058B1 (en) | 2000-05-21 |
Family
ID=9514412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JO19982058A JO2058B1 (en) | 1997-12-10 | 1998-11-29 | New derivatives of echinocandine, their preparation process and their use as fungicides |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN101333249A (en) |
| FR (1) | FR2772028B1 (en) |
| JO (1) | JO2058B1 (en) |
| ZA (1) | ZA9811158B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2464977B1 (en) * | 2009-08-14 | 2014-06-25 | Xellia Pharmaceuticals ApS | Method of detecting pneumocandin compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5516757A (en) * | 1994-09-16 | 1996-05-14 | Merck & Co., Inc. | Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use |
| US5516756A (en) * | 1994-10-31 | 1996-05-14 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
| WO1996022784A1 (en) * | 1995-01-26 | 1996-08-01 | Merck & Co., Inc. | Novel antifungal cyclohexapeptides |
-
1997
- 1997-12-10 FR FR9715628A patent/FR2772028B1/en not_active Expired - Fee Related
-
1998
- 1998-11-29 JO JO19982058A patent/JO2058B1/en active
- 1998-12-07 ZA ZA9811158A patent/ZA9811158B/en unknown
- 1998-12-09 CN CNA2008101305266A patent/CN101333249A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2772028A1 (en) | 1999-06-11 |
| FR2772028B1 (en) | 2000-02-04 |
| CN101333249A (en) | 2008-12-31 |
| ZA9811158B (en) | 1999-12-07 |
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