JO1814B1 - Therapeutic agents - Google Patents
Therapeutic agentsInfo
- Publication number
- JO1814B1 JO1814B1 JO19941814A JOP19941814A JO1814B1 JO 1814 B1 JO1814 B1 JO 1814B1 JO 19941814 A JO19941814 A JO 19941814A JO P19941814 A JOP19941814 A JO P19941814A JO 1814 B1 JO1814 B1 JO 1814B1
- Authority
- JO
- Jordan
- Prior art keywords
- alkyl
- optionally substituted
- alk
- alkoxy
- alkanoyl
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A compound of formula (I) having immunomodulatory activity or a pharmaceutically acceptable salt thereof, in which R1, R2 and R3 are hydrogen; halo; cyano; hydroxy(C1-6)-alkyl; C1-6 alkyl; C1-6 alkoxy; C2-6 alkanoyl; C2-6 alkoxycarbonyl; C2-6 alkoxycarbonyl-(C1-6) alkyl; carboxy; nitro; imidazolyl; carboxy(C1-6)-alkyl; C2-6 alkanoyl-(C1-6)alkyl; C1-6 alkoxy(C1-6)alkyl; NR21R22; R23R24N-(C1-6) alkyl; CONR25R26; R27R28NCO(C1-6)-alkyl; S(O)hR29; optionally substituted phenyl, phenoxy or benzyloxy groups; or R1 and R2 together with the phenyl group to which they are attached form a naphthyl group; or R1 together with X and the phenyl group to which they are attached form a tetrahydronaphthyl group; X is a bond, a sulphur atom, an oxygen atom, vinylene, carbonyl or -NHCO-; alk<1> and alk<2> represent a C1-6 alkylene chain optionally substituted by one or more C1-4 alkyl groups; b is 0 or 1; Y is a saturated 5 or 6 membered heterocyclic ring containing 1 or 2 nitrogen atoms, optionally substituted by C1-6 alkyl, hydroxy(C1-6)alkyl and (C1-6)alkoxy(C1-6)alkyl; R8 is hydrogen or C1-4alkyl; k is 0 or 1; Z is an optionally substituted aromatic heterocyclic ring system comprising imidazolyl, triazolyl and tetrazolyl, optionally having a benzene ring or a pyridine ring fused thereto, connected to alk<2> via a nitrogen atom. Pharmaceutical compositions, processes to make and uses of compounds (I) are claimed.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JO19941814A JO1814B1 (en) | 1994-12-13 | 1994-12-13 | Therapeutic agents |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JO19941814A JO1814B1 (en) | 1994-12-13 | 1994-12-13 | Therapeutic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
JO1814B1 true JO1814B1 (en) | 1995-07-05 |
Family
ID=48142178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JO19941814A JO1814B1 (en) | 1994-12-13 | 1994-12-13 | Therapeutic agents |
Country Status (1)
Country | Link |
---|---|
JO (1) | JO1814B1 (en) |
-
1994
- 1994-12-13 JO JO19941814A patent/JO1814B1/en active
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