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Preparation Of Compounds By Using Micro-Organisms
(AREA)
Abstract
The present invention relates to a process for the isolation of mevinolin by dissolving the active ingredient from the biomass into the fermentation liquor and subsequently separating it from the filtered fermentation liquor, which comprises carrying out the dissolution at a pH value between 7.5 and 10.0, preferably between 8.0 and 9.0, separating the active ingredient from the filtered liquor at a pH value between 4.5 and 1.0, preferably between 2.2 and 2.0, filtering and purifying it by methods known per se, preferably by recrystallization.
JO19931778A1993-12-011993-12-01Process for the isolation and purification of mevinolin
JO1778B1
(en)