ITUB20160256A1 - ESTERIFIED WATER-BASED HYDRO-PERSONS DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF TOLVAPTAN - Google Patents
ESTERIFIED WATER-BASED HYDRO-PERSONS DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF TOLVAPTANInfo
- Publication number
- ITUB20160256A1 ITUB20160256A1 ITUB2016A000256A ITUB20160256A ITUB20160256A1 IT UB20160256 A1 ITUB20160256 A1 IT UB20160256A1 IT UB2016A000256 A ITUB2016A000256 A IT UB2016A000256A IT UB20160256 A ITUB20160256 A IT UB20160256A IT UB20160256 A1 ITUB20160256 A1 IT UB20160256A1
- Authority
- IT
- Italy
- Prior art keywords
- tolvaptan
- persons
- synthesis
- derivatives
- esterified water
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- GYHCTFXIZSNGJT-UHFFFAOYSA-N tolvaptan Chemical compound CC1=CC=CC=C1C(=O)NC(C=C1C)=CC=C1C(=O)N1C2=CC=C(Cl)C=C2C(O)CCC1 GYHCTFXIZSNGJT-UHFFFAOYSA-N 0.000 title 1
- 229960001256 tolvaptan Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITUB2016A000256A ITUB20160256A1 (en) | 2016-01-15 | 2016-01-15 | ESTERIFIED WATER-BASED HYDRO-PERSONS DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF TOLVAPTAN |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITUB2016A000256A ITUB20160256A1 (en) | 2016-01-15 | 2016-01-15 | ESTERIFIED WATER-BASED HYDRO-PERSONS DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF TOLVAPTAN |
Publications (1)
Publication Number | Publication Date |
---|---|
ITUB20160256A1 true ITUB20160256A1 (en) | 2017-07-15 |
Family
ID=55860965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITUB2016A000256A ITUB20160256A1 (en) | 2016-01-15 | 2016-01-15 | ESTERIFIED WATER-BASED HYDRO-PERSONS DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF TOLVAPTAN |
Country Status (1)
Country | Link |
---|---|
IT (1) | ITUB20160256A1 (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2867187A1 (en) * | 2004-03-02 | 2005-09-09 | Centre Nat Rech Scient | PROCESS FOR THE PREPARATION OF BENZAZEPINES AND DERIVATIVES THEREOF |
WO2007026971A2 (en) * | 2005-09-02 | 2007-03-08 | Otsuka Pharmaceutical Co., Ltd. | Process for preparing benzazepine compounds or salts thereof |
-
2016
- 2016-01-15 IT ITUB2016A000256A patent/ITUB20160256A1/en unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2867187A1 (en) * | 2004-03-02 | 2005-09-09 | Centre Nat Rech Scient | PROCESS FOR THE PREPARATION OF BENZAZEPINES AND DERIVATIVES THEREOF |
WO2007026971A2 (en) * | 2005-09-02 | 2007-03-08 | Otsuka Pharmaceutical Co., Ltd. | Process for preparing benzazepine compounds or salts thereof |
Non-Patent Citations (1)
Title |
---|
CORDERO-VARGAS A ET AL: "A flexible approach for the preparation of substituted benzazepines: Application to the synthesis of tolvaptan", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB, vol. 14, no. 18, 15 September 2006 (2006-09-15), pages 6165 - 6173, XP027992895, ISSN: 0968-0896, [retrieved on 20060915] * |
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