ITUA20164043A1 - Process for the preparation of 3β-hydroxy-17- (1H-benzimidazol-1-yl) androsta-5,16-diene - Google Patents

Process for the preparation of 3β-hydroxy-17- (1H-benzimidazol-1-yl) androsta-5,16-diene

Info

Publication number
ITUA20164043A1
ITUA20164043A1 ITUA2016A004043A ITUA20164043A ITUA20164043A1 IT UA20164043 A1 ITUA20164043 A1 IT UA20164043A1 IT UA2016A004043 A ITUA2016A004043 A IT UA2016A004043A IT UA20164043 A ITUA20164043 A IT UA20164043A IT UA20164043 A1 ITUA20164043 A1 IT UA20164043A1
Authority
IT
Italy
Prior art keywords
androsta
benzimidazol
diene
hydroxy
preparation
Prior art date
Application number
ITUA2016A004043A
Other languages
Italian (it)
Inventor
Francesco Barbieri
Roberto Lenna
Original Assignee
Ind Chimica Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind Chimica Srl filed Critical Ind Chimica Srl
Priority to ITUA2016A004043A priority Critical patent/ITUA20164043A1/en
Priority to PCT/IB2017/053147 priority patent/WO2017208132A1/en
Priority to ES201890072A priority patent/ES2697706R1/en
Priority to CH01484/18A priority patent/CH714035B1/en
Publication of ITUA20164043A1 publication Critical patent/ITUA20164043A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
ITUA2016A004043A 2016-06-01 2016-06-01 Process for the preparation of 3β-hydroxy-17- (1H-benzimidazol-1-yl) androsta-5,16-diene ITUA20164043A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ITUA2016A004043A ITUA20164043A1 (en) 2016-06-01 2016-06-01 Process for the preparation of 3β-hydroxy-17- (1H-benzimidazol-1-yl) androsta-5,16-diene
PCT/IB2017/053147 WO2017208132A1 (en) 2016-06-01 2017-05-29 Process for the preparation of galeterone
ES201890072A ES2697706R1 (en) 2016-06-01 2017-05-29 Process for the Preparation of Galeterone.
CH01484/18A CH714035B1 (en) 2016-06-01 2017-05-29 Process for the preparation of 3Beta-hydroxy-17- (1H-benzimidazol-1-yl) androsta-5,16-diene.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUA2016A004043A ITUA20164043A1 (en) 2016-06-01 2016-06-01 Process for the preparation of 3β-hydroxy-17- (1H-benzimidazol-1-yl) androsta-5,16-diene

Publications (1)

Publication Number Publication Date
ITUA20164043A1 true ITUA20164043A1 (en) 2017-12-01

Family

ID=57184596

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUA2016A004043A ITUA20164043A1 (en) 2016-06-01 2016-06-01 Process for the preparation of 3β-hydroxy-17- (1H-benzimidazol-1-yl) androsta-5,16-diene

Country Status (1)

Country Link
IT (1) ITUA20164043A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010091306A1 (en) * 2009-02-05 2010-08-12 Tokai Pharmaceuticals Novel prodrugs of steroidal cyp17 inhibitors/antiandrogens
US20110034428A1 (en) * 2009-08-07 2011-02-10 Tokai Pharmaceuticals, Inc. Treatment of Prostate Cancer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010091306A1 (en) * 2009-02-05 2010-08-12 Tokai Pharmaceuticals Novel prodrugs of steroidal cyp17 inhibitors/antiandrogens
US20110034428A1 (en) * 2009-08-07 2011-02-10 Tokai Pharmaceuticals, Inc. Treatment of Prostate Cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ANDERSON ET AL: "TOOLS FOR PURIFYING THE PRODUCT: COLUMN CHROMATOGRAPHY, CRYSTALLIZATION AND RESLURRYING", PRACTICAL PROCESS RESEARCH AND DEVELOPMENT, ACADEMIC PRESS, SAN DIEGO, US, 1 January 2000 (2000-01-01), pages 223 - 247, XP002382432 *
HANDRATTA VENKATESH D ET AL: "Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens: Synthesis, in Vitro Biological Activity, Pharmacokinetics, and Antitumor Activity in the LAPC4 Human Prostate Cancer Xenograft Model", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 48, no. 8, 25 March 2005 (2005-03-25), pages 2972 - 2984, XP002535274, ISSN: 0022-2623, DOI: 10.1021/JM040202W *

Similar Documents

Publication Publication Date Title
ES2964690T3 (en) Method for synthesizing 5' capped RNA
BR112016030694A2 (en) process for the preparation of ethylene glycol from sugars
EP3385305A4 (en) Method for producing protein solution
PT3397648T (en) Method for deacetylation of biopolymers
ZA201706795B (en) Process for the preparation of dicycloplatin
EP3393468A4 (en) Methods for treating immunodeficiency disease
IT201800009683A1 (en) PROCESS FOR THE PREPARATION OF 3A-HYDROXY-5A-PREGNAN-20-ONE (BREXANOLONE)
EP3395530A4 (en) Method for producing structure
GB201513098D0 (en) Catalytically active protein aggregates and methods for producing the same
EP3382031A4 (en) Method for producing fibroin-like protein
EP3284748A4 (en) Method for preparing deoxycholic acid
HRP20190403T1 (en) Process for the preparation of lacosamide
EP3296287A4 (en) Method for purifying 1,4-diaminobutane
ZA201801991B (en) Process for the preparation of monochloroacetic acid
EP3524957A4 (en) Tissue dividing jig
EP3519382A4 (en) An improved process for the preparation of lacosamide
EP3253772B8 (en) Process for the preparation of diosmin
ITUB20160480A1 (en) Method for the preparation of Metaraminol.
GB2561089B (en) Process for the preparation of 17beta-hydroxy-des-a-androst-9, 10-en-5-one
GB2564185B (en) Process for the preparation of derivatives of benzodioxole
EP3418535A4 (en) Method for producing blade structure
ITUA20161550A1 (en) Procedure for the production of RNA
ITUA20164793A1 (en) Process for the preparation of 3β-hydroxy-17- (1H-benzimidazol-1-yl) androsta-5,16-diene
ITUA20164043A1 (en) Process for the preparation of 3β-hydroxy-17- (1H-benzimidazol-1-yl) androsta-5,16-diene
IT201600121375A1 (en) PROCESS FOR THE PREPARATION OF 3ß-HYDROXY-17- (1H-BENZIMIDAZOL-1-IL) ANDROSTA-5,16-DIENE