ITUA20163140A1 - Cellule caricate con nanoparticelle di oro per l'uso nella diagnosi e/o nel trattamento del melanoma - Google Patents

Cellule caricate con nanoparticelle di oro per l'uso nella diagnosi e/o nel trattamento del melanoma

Info

Publication number
ITUA20163140A1
ITUA20163140A1 ITUA2016A003140A ITUA20163140A ITUA20163140A1 IT UA20163140 A1 ITUA20163140 A1 IT UA20163140A1 IT UA2016A003140 A ITUA2016A003140 A IT UA2016A003140A IT UA20163140 A ITUA20163140 A IT UA20163140A IT UA20163140 A1 ITUA20163140 A1 IT UA20163140A1
Authority
IT
Italy
Prior art keywords
melanoma
diagnosis
treatment
gold nanoparticles
cells loaded
Prior art date
Application number
ITUA2016A003140A
Other languages
English (en)
Inventor
Rosso Mario Del
Anna Laurenzana
Gabriella Fibbi
Francesca Margheri
Anastasia Chilla'
Angela Zoppi
Giancarlo Margheri
Original Assignee
Univ Degli Studi Di Firenze
Consiglio Nazionale Ricerche
Plasma Diagnostics And Tech Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Di Firenze, Consiglio Nazionale Ricerche, Plasma Diagnostics And Tech Srl filed Critical Univ Degli Studi Di Firenze
Priority to ITUA2016A003140A priority Critical patent/ITUA20163140A1/it
Priority to JP2019510485A priority patent/JP2019519249A/ja
Priority to MX2018013435A priority patent/MX2018013435A/es
Priority to EP17733002.4A priority patent/EP3452099B1/en
Priority to US16/096,505 priority patent/US20190142980A1/en
Priority to DK17733002.4T priority patent/DK3452099T3/da
Priority to CN201780027927.6A priority patent/CN109219452B/zh
Priority to PCT/IB2017/052567 priority patent/WO2017191572A1/en
Publication of ITUA20163140A1 publication Critical patent/ITUA20163140A1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1203—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules in a form not provided for by groups A61K51/1206 - A61K51/1296, e.g. cells, cell fragments, viruses, virus capsides, ghosts, red blood cells, viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/242—Gold; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0065—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ITUA2016A003140A 2016-05-04 2016-05-04 Cellule caricate con nanoparticelle di oro per l'uso nella diagnosi e/o nel trattamento del melanoma ITUA20163140A1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ITUA2016A003140A ITUA20163140A1 (it) 2016-05-04 2016-05-04 Cellule caricate con nanoparticelle di oro per l'uso nella diagnosi e/o nel trattamento del melanoma
JP2019510485A JP2019519249A (ja) 2016-05-04 2017-05-03 黒色腫の診断及び／又は治療に使用される金ナノ粒子がロードされた細胞
MX2018013435A MX2018013435A (es) 2016-05-04 2017-05-03 Celulas cargadas con nanoparticulas de oro para su uso en el diagnostico y/o tratamiento del melanoma.
EP17733002.4A EP3452099B1 (en) 2016-05-04 2017-05-03 Cells loaded with gold nanoparticles for use in the diagnosis and/or treatment of melanoma
US16/096,505 US20190142980A1 (en) 2016-05-04 2017-05-03 Cells loaded with gold nanoparticles for use in the diagnosis and/or treatment of melanoma
DK17733002.4T DK3452099T3 (da) 2016-05-04 2017-05-03 Celler ladet med guldnanopartikler til anvendelse inden for diagnosen og/eller behandlingen af melanom
CN201780027927.6A CN109219452B (zh) 2016-05-04 2017-05-03 用于诊断和/或治疗黑素瘤的加载有金纳米颗粒的细胞
PCT/IB2017/052567 WO2017191572A1 (en) 2016-05-04 2017-05-03 Cells loaded with gold nanoparticles for use in the diagnosis and/or treatment of melanoma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUA2016A003140A ITUA20163140A1 (it) 2016-05-04 2016-05-04 Cellule caricate con nanoparticelle di oro per l'uso nella diagnosi e/o nel trattamento del melanoma

Publications (1)

Publication Number Publication Date
ITUA20163140A1 true ITUA20163140A1 (it) 2017-11-04

Family

ID=56894068

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUA2016A003140A ITUA20163140A1 (it) 2016-05-04 2016-05-04 Cellule caricate con nanoparticelle di oro per l'uso nella diagnosi e/o nel trattamento del melanoma

Country Status (8)

Country Link
US (1) US20190142980A1 (it)
EP (1) EP3452099B1 (it)
JP (1) JP2019519249A (it)
CN (1) CN109219452B (it)
DK (1) DK3452099T3 (it)
IT (1) ITUA20163140A1 (it)
MX (1) MX2018013435A (it)
WO (1) WO2017191572A1 (it)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5782029B2 (ja) * 2009-08-12 2015-09-24 デューク ユニバーシティーＤｕｋｅ Ｕｎｉｖｅｒｓｉｔｙ 細胞でコーティングされた移植可能デバイス

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
LAURENZANA ANNA ET AL: "Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme", ONCOTARGET, vol. 5, no. 11, June 2014 (2014-06-01), pages 3711 - 3727, XP002765711 *
MARGHERI GIANCARLO ET AL: "Tumor-tropic endothelial colony forming cells (ECFCs) loaded with near-infrared sensitive Au nanoparticles: A "cellular stove" approach to the photoablation of melanoma", ONCOTARGET, vol. 7, no. 26, June 2016 (2016-06-01), pages 39846 - 39860, XP002765712 *
SEOKYUNG KANG ET AL: "Mesenchymal Stem Cells Aggregate and Deliver Gold Nanoparticles to Tumors for Photothermal Therapy", ACS NANO, vol. 9, no. 10, 27 October 2015 (2015-10-27), US, pages 9678 - 9690, XP055333436, ISSN: 1936-0851, DOI: 10.1021/acsnano.5b02207 *
WANG H-H ET AL: "Fluorescent gold nanoclusters as a biocompatible marker for in vitro and in vivo tracking of endothelial cells", ACS NANO 20110628 AMERICAN CHEMICAL SOCIETY USA, vol. 5, no. 6, 28 June 2011 (2011-06-28), pages 4337 - 4344, XP002765709, DOI: 10.1021/NN102752A *

Also Published As

Publication number Publication date
DK3452099T3 (da) 2020-06-29
CN109219452B (zh) 2021-10-26
JP2019519249A (ja) 2019-07-11
EP3452099B1 (en) 2020-04-22
WO2017191572A1 (en) 2017-11-09
US20190142980A1 (en) 2019-05-16
EP3452099A1 (en) 2019-03-13
MX2018013435A (es) 2019-02-28
CN109219452A (zh) 2019-01-15

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