ITTO990703A0 - PROCEDURE FOR THE PREPARATION OF INTERMEDIATE PRODUCTS IN THE SYNTHESIS OF LISINOPRIL. - Google Patents
PROCEDURE FOR THE PREPARATION OF INTERMEDIATE PRODUCTS IN THE SYNTHESIS OF LISINOPRIL.Info
- Publication number
- ITTO990703A0 ITTO990703A0 IT99TO000703A ITTO990703A ITTO990703A0 IT TO990703 A0 ITTO990703 A0 IT TO990703A0 IT 99TO000703 A IT99TO000703 A IT 99TO000703A IT TO990703 A ITTO990703 A IT TO990703A IT TO990703 A0 ITTO990703 A0 IT TO990703A0
- Authority
- IT
- Italy
- Prior art keywords
- lisinopril
- synthesis
- procedure
- preparation
- intermediate products
- Prior art date
Links
- 108010007859 Lisinopril Proteins 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000013067 intermediate product Substances 0.000 title 1
- RLAWWYSOJDYHDC-BZSNNMDCSA-N lisinopril Chemical compound C([C@H](N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(O)=O)C(O)=O)CC1=CC=CC=C1 RLAWWYSOJDYHDC-BZSNNMDCSA-N 0.000 title 1
- 229960002394 lisinopril Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/44—Two oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Control Of Vending Devices And Auxiliary Devices For Vending Devices (AREA)
- Farming Of Fish And Shellfish (AREA)
- Table Devices Or Equipment (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999TO000703A IT1307265B1 (en) | 1999-08-09 | 1999-08-09 | PROCEDURE FOR THE PREPARATION OF INTERMEDIATE PRODUCTS IN THE SYNTHESID OF LISINOPRIL. |
| AU72742/00A AU7274200A (en) | 1999-08-09 | 2000-08-09 | Process for the preparation of lysine-carboxyanhydride intermediates in the synthesis of lisinopril |
| PCT/EP2000/007743 WO2001010851A1 (en) | 1999-08-09 | 2000-08-09 | Process for the preparation of lysine-carboxyanhydride intermediates in the synthesis of lisinopril |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999TO000703A IT1307265B1 (en) | 1999-08-09 | 1999-08-09 | PROCEDURE FOR THE PREPARATION OF INTERMEDIATE PRODUCTS IN THE SYNTHESID OF LISINOPRIL. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITTO990703A0 true ITTO990703A0 (en) | 1999-08-09 |
| ITTO990703A1 ITTO990703A1 (en) | 2001-02-09 |
| IT1307265B1 IT1307265B1 (en) | 2001-10-30 |
Family
ID=11418023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT1999TO000703A IT1307265B1 (en) | 1999-08-09 | 1999-08-09 | PROCEDURE FOR THE PREPARATION OF INTERMEDIATE PRODUCTS IN THE SYNTHESID OF LISINOPRIL. |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU7274200A (en) |
| IT (1) | IT1307265B1 (en) |
| WO (1) | WO2001010851A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0102252B1 (en) | 2001-04-10 | 2013-10-22 | Angiotensin II AT1 Receptor Antagonist Controlled Release System, Pharmaceutical Composition and Use | |
| AU2002345522A1 (en) * | 2002-06-19 | 2004-01-06 | Eos Eczacibasi Ozgun Kimyasal Urunler Sanyi Ve Ti Caret A.S. | Process for the production of lisinopril |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5019521A (en) * | 1990-03-12 | 1991-05-28 | Photest Diagnostics, Inc. | Paired polypeptides |
| IT1299341B1 (en) * | 1998-02-09 | 2000-03-16 | Pfc Italiana Srl | PROCESS FOR THE PRODUCTION OF INTERMEDIATE ALKOXY CARBONYL DIPEPTIDES IN THE SYNTHESIS OF LISINOPRIL. |
-
1999
- 1999-08-09 IT IT1999TO000703A patent/IT1307265B1/en active
-
2000
- 2000-08-09 AU AU72742/00A patent/AU7274200A/en not_active Abandoned
- 2000-08-09 WO PCT/EP2000/007743 patent/WO2001010851A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001010851A1 (en) | 2001-02-15 |
| ITTO990703A1 (en) | 2001-02-09 |
| WO2001010851B1 (en) | 2001-06-21 |
| IT1307265B1 (en) | 2001-10-30 |
| AU7274200A (en) | 2001-03-05 |
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